Osteonecrosis of the Jaw in the Absence of Antiresorptive or Antiangiogenic Exposure: A Series of 6 Cases
Identifieur interne : 000632 ( Main/Exploration ); précédent : 000631; suivant : 000633Osteonecrosis of the Jaw in the Absence of Antiresorptive or Antiangiogenic Exposure: A Series of 6 Cases
Auteurs : Tara L. Aghaloo ; Sotirios TetradisSource :
- Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons [ 0278-2391 ] ; 2016.
Abstract
Medication-related osteonecrosis of the jaws (MRONJ) is a well-described complication of anti-resorptive and antiangiogenic medications. Although osteonecrosis can be associated with other inciting events and medications, such as trauma, infection, steroids, chemotherapy, and coagulation disorders, these are rarely reported in the literature.
This is a six case series of MRONJ associated with medications other than anti-resorptive or antiangiogenic drugs.
Patient demographics, incitingevent, location, stage, imaging findings, and outcome are reported.
With the continued development and clinical use of new biologic medications for diseases such as cancer and rheumatoid arthritis, it is important to continue to evaluate their effects on the oral cavity. The degree of risk for osteonecrosis in patients taking these new classes of drugs is uncertain but warrants awareness and monitoring.
Url:
DOI: 10.1016/j.joms.2016.07.019
PubMed: 27569557
PubMed Central: 5527276
Affiliations:
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