Plasma cell mucositis with gingival enlargement and severe periodontitis
Identifieur interne : 001815 ( Main/Exploration ); précédent : 001814; suivant : 001816Plasma cell mucositis with gingival enlargement and severe periodontitis
Auteurs : Shalini R. Gupta ; Rajiva Gupta ; Ravindra K. Saran ; Sriram KrishnanSource :
- Journal of Indian Society of Periodontology [ 0972-124X ] ; 2014.
Abstract
Plasma cell mucositis (PCM) is a very rare, chronic, multifocal, idiopathic, non-neoplastic plasma cell proliferative disorder of the upper aerodigestive tract. The classic clinical presentation is an intensely erythematous mucosa with surface changes described variously as papillomatous, cobblestone, nodular or velvety. It is a very rare condition <50 cases reported in literature. A 72-year-old male patient complained of sore throat, stomatodynia, dysphagia, multiple oral ulcers, enlarged swollen bleeding gums and mobile teeth. There was chronic inflammatory enlargement of the gingiva and palate with severe periodontitis. Histopathological examination revealed a hyperplastic epithelium with a dense infiltrate of mature polyclonal plasma cells in the superficial layer of the lamina propria. PCM is a diagnosis of exclusion, to be differentiated from other infective, reactive, autoimmune, allergic and neoplastic disorders with plasma cell infiltrates. Management with surgical and immunosuppressive therapy is mostly ineffective with short remissions and frequent relapses.
Url:
DOI: 10.4103/0972-124X.134583
PubMed: 25024555
PubMed Central: 4095634
Affiliations:
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Gupta</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Gupta, Rajiva" sort="Gupta, Rajiva" uniqKey="Gupta R" first="Rajiva" last="Gupta">Rajiva Gupta</name><affiliation><nlm:aff id="aff2"><italic>Department of Rheumatology and Clinical Immunology, Medanta Medicity, Gurgaon, Haryana, India</italic></nlm:aff></affiliation></author><author><name sortKey="Saran, Ravindra K" sort="Saran, Ravindra K" uniqKey="Saran R" first="Ravindra K." last="Saran">Ravindra K. 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The classic clinical presentation is an intensely erythematous mucosa with surface changes described variously as papillomatous, cobblestone, nodular or velvety. It is a very rare condition <50 cases reported in literature. A 72-year-old male patient complained of sore throat, stomatodynia, dysphagia, multiple oral ulcers, enlarged swollen bleeding gums and mobile teeth. There was chronic inflammatory enlargement of the gingiva and palate with severe periodontitis. Histopathological examination revealed a hyperplastic epithelium with a dense infiltrate of mature polyclonal plasma cells in the superficial layer of the lamina propria. PCM is a diagnosis of exclusion, to be differentiated from other infective, reactive, autoimmune, allergic and neoplastic disorders with plasma cell infiltrates. 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Gupta</name><name sortKey="Krishnan, Sriram" sort="Krishnan, Sriram" uniqKey="Krishnan S" first="Sriram" last="Krishnan">Sriram Krishnan</name><name sortKey="Saran, Ravindra K" sort="Saran, Ravindra K" uniqKey="Saran R" first="Ravindra K." last="Saran">Ravindra K. Saran</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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