EdenteV2, Main, Exploration, bibRecord, 008830

Treatment of peri‐implantitis by local delivery of tetracycline

Identifieur interne : 008830 ( Main/Exploration ); précédent : 008829; suivant : 008831

Treatment of peri‐implantitis by local delivery of tetracycline

Auteurs : Andrea Mombelli ; Andreas Feloutzis [Suisse] ; Urs Br Gger [Suisse] ; Niklaus P. Lang [Suisse]

Source :

Clinical Oral Implants Research [ 0905-7161 ] ; 2001-08.

RBID : ISTEX:88A2FE878CD6992FEAC118E763CE944D1151BD61

Descripteurs français

Wicri :
- topic : Médecine dentaire, Micro-organisme.

English descriptors

Abstract

Abstract: The purpose of this study was to investigate the clinical, microbiological and radiological effects of peri‐implantitis therapy by local delivery of tetracycline. In 25 partially edentulous patients, 30 implants with radiographic evidence of circumferential bone loss, and peri‐implant probing depths ≥5 mm were treated with polymeric tetracycline HCl‐containing fibers. Clinical and microbial parameters were recorded at baseline, and 1, 3, 6, and 12 months (M) after treatment. Standardized radiographs were obtained at baseline, M3, and one year after treatment. Two patients were discontinued from the study after 180 days because of persisting active peri‐implantitis with pus formation. The remaining subjects showed a significant decrease of mean peri‐implant probing depth from 6.0 to 4.1 mm (M1, P<0.001), which was maintained over 12 months. In comparison to baseline, the bleeding tendency was significantly reduced after one month, and thereafter (P<0.001). No significant recession of the mucosal margin was noted. The radiologically determined distance from the shoulder of the implant to the bottom of the bony defect decreased slightly, but not significantly, from 5.2 to 4.9 mm. At M1, M3 and M6, mean total anaerobic cultivable bacterial counts were significantly lower than at baseline (P<0.001). A significant decrease in frequency of detection was noted for Prevotella intermedia/nigrescens, Fusobacterium sp., Bacteroides forsythus, and Campylobacter rectus (P<0.01). Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, and Eikenella corrodens had very low baseline frequencies that could not be significantly suppressed further.

Url:

https://api.istex.fr/document/88A2FE878CD6992FEAC118E763CE944D1151BD61/fulltext/pdf

DOI: 10.1034/j.1600-0501.2001.012004287.x

Affiliations:

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Le document en format XML

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<author><name sortKey="Br Gger, Urs" sort="Br Gger, Urs" uniqKey="Br Gger U" first="Urs" last="Br Gger">Urs Br Gger</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Actinobacillus actinomycetemcomitans</term>
<term>Actinomyces naeslundii</term>
<term>Actinomycetemcomitans</term>
<term>Anaerobic</term>
<term>Anaerobic rods</term>
<term>Bacterial contamination</term>
<term>Bacterial morphotypes</term>
<term>Bacteroides forsythus</term>
<term>Baseline</term>
<term>Bone density</term>
<term>Campylobacter rectus</term>
<term>Clin</term>
<term>Clinical outcome</term>
<term>Clinical parameters</term>
<term>Corrodens</term>
<term>Cultivable counts</term>
<term>Deepest site</term>
<term>Densitometric image analysis</term>
<term>Dental medicine</term>
<term>Digital image processing</term>
<term>Direct contact</term>
<term>Edentulous patients</term>
<term>Eikenella corrodens</term>
<term>Forsythus</term>
<term>Full body screws</term>
<term>Gingivalis</term>
<term>Impl</term>
<term>Implant</term>
<term>Implant score</term>
<term>Implant shoulder</term>
<term>Implant surface</term>
<term>Implant surfaces</term>
<term>Implants research</term>
<term>Lang</term>
<term>Liberation locale</term>
<term>Local delivery</term>
<term>Longitudinal</term>
<term>Longitudinal changes</term>
<term>Longitudinal development</term>
<term>Metres cliniques</term>
<term>Microbiological</term>
<term>Microbiological parameters</term>
<term>Microbiological procedures</term>
<term>Microorganism</term>
<term>Mombelli</term>
<term>Mpli</term>
<term>Oral impl</term>
<term>Other subjects</term>
<term>Periimplantitis</term>
<term>Periodontal</term>
<term>Periodontal research</term>
<term>Plaque index</term>
<term>Pocket depth</term>
<term>Polymeric tetracycline</term>
<term>Porphyromonas gingivalis</term>
<term>Positive effect</term>
<term>Positive values</term>
<term>Present study</term>
<term>Radiograph</term>
<term>Radiographic evidence</term>
<term>Radiological effects</term>
<term>Radiological results</term>
<term>Rectus</term>
<term>Target microorganisms</term>
<term>Tetracycline</term>
<term>Total cultivable counts</term>
<term>Vertical dimensions</term>
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<keywords scheme="Teeft" xml:lang="en"><term>Actinobacillus actinomycetemcomitans</term>
<term>Actinomyces naeslundii</term>
<term>Actinomycetemcomitans</term>
<term>Anaerobic</term>
<term>Anaerobic rods</term>
<term>Bacterial contamination</term>
<term>Bacterial morphotypes</term>
<term>Bacteroides forsythus</term>
<term>Baseline</term>
<term>Bone density</term>
<term>Campylobacter rectus</term>
<term>Clin</term>
<term>Clinical outcome</term>
<term>Clinical parameters</term>
<term>Corrodens</term>
<term>Cultivable counts</term>
<term>Deepest site</term>
<term>Densitometric image analysis</term>
<term>Dental medicine</term>
<term>Digital image processing</term>
<term>Direct contact</term>
<term>Edentulous patients</term>
<term>Eikenella corrodens</term>
<term>Forsythus</term>
<term>Full body screws</term>
<term>Gingivalis</term>
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<term>Implant</term>
<term>Implant score</term>
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<term>Implant surfaces</term>
<term>Implants research</term>
<term>Lang</term>
<term>Liberation locale</term>
<term>Local delivery</term>
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<term>Longitudinal development</term>
<term>Metres cliniques</term>
<term>Microbiological</term>
<term>Microbiological parameters</term>
<term>Microbiological procedures</term>
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<term>Mombelli</term>
<term>Mpli</term>
<term>Oral impl</term>
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<term>Periodontal</term>
<term>Periodontal research</term>
<term>Plaque index</term>
<term>Pocket depth</term>
<term>Polymeric tetracycline</term>
<term>Porphyromonas gingivalis</term>
<term>Positive effect</term>
<term>Positive values</term>
<term>Present study</term>
<term>Radiograph</term>
<term>Radiographic evidence</term>
<term>Radiological effects</term>
<term>Radiological results</term>
<term>Rectus</term>
<term>Target microorganisms</term>
<term>Tetracycline</term>
<term>Total cultivable counts</term>
<term>Vertical dimensions</term>
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<front><div type="abstract">Abstract: The purpose of this study was to investigate the clinical, microbiological and radiological effects of peri‐implantitis therapy by local delivery of tetracycline. In 25 partially edentulous patients, 30 implants with radiographic evidence of circumferential bone loss, and peri‐implant probing depths ≥5 mm were treated with polymeric tetracycline HCl‐containing fibers. Clinical and microbial parameters were recorded at baseline, and 1, 3, 6, and 12 months (M) after treatment. Standardized radiographs were obtained at baseline, M3, and one year after treatment. Two patients were discontinued from the study after 180 days because of persisting active peri‐implantitis with pus formation. The remaining subjects showed a significant decrease of mean peri‐implant probing depth from 6.0 to 4.1 mm (M1, P<0.001), which was maintained over 12 months. In comparison to baseline, the bleeding tendency was significantly reduced after one month, and thereafter (P<0.001). No significant recession of the mucosal margin was noted. The radiologically determined distance from the shoulder of the implant to the bottom of the bony defect decreased slightly, but not significantly, from 5.2 to 4.9 mm. At M1, M3 and M6, mean total anaerobic cultivable bacterial counts were significantly lower than at baseline (P<0.001). A significant decrease in frequency of detection was noted for Prevotella intermedia/nigrescens, Fusobacterium sp., Bacteroides forsythus, and Campylobacter rectus (P<0.01). Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, and Eikenella corrodens had very low baseline frequencies that could not be significantly suppressed further.</div>
</front>
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Treatment of peri‐implantitis by local delivery of tetracycline

Treatment of peri‐implantitis by local delivery of tetracycline

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri