Molecular characterization of Candida spp. isolated from the oral cavities of patients from diverse clinical settings
Identifieur interne : 000A37 ( Istex/Curation ); précédent : 000A36; suivant : 000A38Molecular characterization of Candida spp. isolated from the oral cavities of patients from diverse clinical settings
Auteurs : Z. M. Al-Karaawi ; M. Manfredi ; A. C. W. Waugh ; M. J. Mccullough [Australie] ; J. Jorge ; C. Scully ; S. R. PorterSource :
- Oral Microbiology and Immunology [ 0902-0055 ] ; 2002-02.
English descriptors
- KwdEn :
- Albicans, Albicans genotypes, Candida, Candida albicans, Clin, Clin microbiol, Cohort, Colonization, Dentate, Denture, Denture status, Diverse settings, Dubliniensis, Genotype, Genotypic, Genotypic distribution, Human virus, Lichen, Lichen planus, Microbiol, Molecular characterization, Molecular methods, Mucosal, Mucosal abnormalities, Nonmucosal disorders, Oral candida, Oral cavities, Oral cavity, Oral lichen planus, Oral medicine patients, Oral pathol, Oral yeast, Orthodontic appliances, Orthodontic patients, Partial dentate, Planus, Present study, Previous research, Previous studies, Previous study, Recurrent aphthous stomatitis, Species level, Subgroup, Yeast.
- Teeft :
- Albicans, Albicans genotypes, Candida, Candida albicans, Clin, Clin microbiol, Cohort, Colonization, Dentate, Denture, Denture status, Diverse settings, Dubliniensis, Genotype, Genotypic, Genotypic distribution, Human virus, Lichen, Lichen planus, Microbiol, Molecular characterization, Molecular methods, Mucosal, Mucosal abnormalities, Nonmucosal disorders, Oral candida, Oral cavities, Oral cavity, Oral lichen planus, Oral medicine patients, Oral pathol, Oral yeast, Orthodontic appliances, Orthodontic patients, Partial dentate, Planus, Present study, Previous research, Previous studies, Previous study, Recurrent aphthous stomatitis, Species level, Subgroup, Yeast.
Abstract
Infections by Candida spp. have increased in medical importance over the past few decades. Our understanding of species identification, commensalisms, pathogenicity, person‐to‐person spread, and the development of antifungal resistance within specific strains has been greatly enhanced by the utilization of molecular epidemiological methodology. The aim of the current research was to assess the quantity, species and molecular characterization of oral yeast isolates from well‐defined cohorts of immunocompetent patients from a diverse range of clinical settings. Oral rinse samples were assessed for the growth of yeast and degree of colonization. Isolates were defined to the species level by both phenotypic and molecular methods and strains were further genotypically subtyped. Significant variation was shown to exist in the number, species and genotypic subgroups of yeast isolated from the oral cavity in different patient groups. This variation could be attributed to the local oral conditions unique to these patient groups.
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DOI: 10.1046/j.0902-0055.2001.00081.x
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Z. M. Al-Karaawi<affiliation><mods:affiliation>Oral Medicine Department, Eastman Dental Institute for Oral Health Care Sciences, University College London, 256 Grays Inn Road, London WC1 9LD, UK,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><mods:affiliation>Dipartimento di Scienze‐Otorino‐Odonto Oftalmologiche e Cervico facciali, Sezione di Odontostomatologia, Università di Parma, Viale Gramsci 14, 43100 Parma, Italy,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><mods:affiliation>Oral Medicine Department, Eastman Dental Institute for Oral Health Care Sciences, University College London, 256 Grays Inn Road, London WC1 9LD, UK,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><mods:affiliation>Oral Medicine Department, Eastman Dental Institute for Oral Health Care Sciences, University College London, 256 Grays Inn Road, London WC1 9LD, UK,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><mods:affiliation>Oral Medicine Department, Eastman Dental Institute for Oral Health Care Sciences, University College London, 256 Grays Inn Road, London WC1 9LD, UK,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><mods:affiliation>Oral Medicine Department, Eastman Dental Institute for Oral Health Care Sciences, University College London, 256 Grays Inn Road, London WC1 9LD, UK,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation>Le document en format XML
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Our understanding of species identification, commensalisms, pathogenicity, person‐to‐person spread, and the development of antifungal resistance within specific strains has been greatly enhanced by the utilization of molecular epidemiological methodology. The aim of the current research was to assess the quantity, species and molecular characterization of oral yeast isolates from well‐defined cohorts of immunocompetent patients from a diverse range of clinical settings. Oral rinse samples were assessed for the growth of yeast and degree of colonization. Isolates were defined to the species level by both phenotypic and molecular methods and strains were further genotypically subtyped. Significant variation was shown to exist in the number, species and genotypic subgroups of yeast isolated from the oral cavity in different patient groups. This variation could be attributed to the local oral conditions unique to these patient groups.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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