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Inflammatory mechanisms linking periodontal diseases to cardiovascular diseases

Identifieur interne : 007171 ( Istex/Corpus ); précédent : 007170; suivant : 007172

Inflammatory mechanisms linking periodontal diseases to cardiovascular diseases

Auteurs : Harvey A. Schenkein ; Bruno G. Loos

Source :

RBID : ISTEX:E4D4B3F2D316D5171279036C0AF2E7C46B8F1450

English descriptors

Abstract

In this article, inflammatory mechanisms that link periodontal diseases to cardiovascular diseases are reviewed.

Url:
DOI: 10.1111/jcpe.12060

Links to Exploration step

ISTEX:E4D4B3F2D316D5171279036C0AF2E7C46B8F1450

Le document en format XML

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<p>Studies in the literature implicate a number of possible mechanisms that could be responsible for increased inflammatory responses in atheromatous lesions due to periodontal infections. These include increased systemic levels of inflammatory mediators stimulated by bacteria and their products at sites distant from the oral cavity, elevated thrombotic and hemostatic markers that promote a prothrombotic state and inflammation, cross‐reactive systemic antibodies that promote inflammation and interact with the atheroma, promotion of dyslipidemia with consequent increases in pro‐inflammatory lipid classes and subclasses, and common genetic susceptibility factors present in both disease leading to increased inflammatory responses.</p>
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