Recurrent aphthous ulcers in Fanconi's anaemia: a case report
Identifieur interne : 006144 ( Istex/Corpus ); précédent : 006143; suivant : 006145Recurrent aphthous ulcers in Fanconi's anaemia: a case report
Auteurs : Feyza Otan ; Gokhan Açikgöz ; Umur Sakallio Lu ; Burcu ÖzkanSource :
- International Journal of Paediatric Dentistry [ 0960-7439 ] ; 2004-05.
English descriptors
- KwdEn :
- Abnormality, Aggressive periodontitis, American journal, Anaemia, Anemia, Aphthous, Aphthous lesion, Aphthous lesions, Aphthous ulcerations, Aplastic, Aplastic anaemia, Aplastic anemia, Apthous stomatitis, Autosomal recessive disorder, Blood counts, Bspd, Case report, Congenital malformations, Dentistry, Fanconi, Fanconi anemia, Growth retardation, Iapd, Implant surgery, International journal, Last blood transfusion, Lesion, Malformation, Malignancy, Ndings, Oral mucosa, Oral ulcerations, Paediatric, Paediatric dentistry, Pediatric, Periodontal, Periodontal examination, Periodontology, Peripheral blood smear, Pfapa, Pfapa syndrome, Physical abnormalities, Physical examination, Recurrent aphthous ulcers, Severe anaemia, Short stature, Squamous cell carcinoma, Transfusion, Ulceration.
- Teeft :
- Abnormality, Aggressive periodontitis, American journal, Anaemia, Anemia, Aphthous, Aphthous lesion, Aphthous lesions, Aphthous ulcerations, Aplastic, Aplastic anaemia, Aplastic anemia, Apthous stomatitis, Autosomal recessive disorder, Blood counts, Bspd, Case report, Congenital malformations, Dentistry, Fanconi, Fanconi anemia, Growth retardation, Iapd, Implant surgery, International journal, Last blood transfusion, Lesion, Malformation, Malignancy, Ndings, Oral mucosa, Oral ulcerations, Paediatric, Paediatric dentistry, Pediatric, Periodontal, Periodontal examination, Periodontology, Peripheral blood smear, Pfapa, Pfapa syndrome, Physical abnormalities, Physical examination, Recurrent aphthous ulcers, Severe anaemia, Short stature, Squamous cell carcinoma, Transfusion, Ulceration.
Abstract
Summary. Fanconi's anaemia (FA) is an autosomal recessive disorder that is clinically characterized by aplastic anaemia, congenital malformations of the renal, cardiac, skeletal and skin structures, and an increased predisposition to malignancies. Patients with FA often present with bleeding and infection, which are symptoms related to thrombocytopenia and neutropenia. There are few reports of the oral manifestations of FA. We describe oral aphthous ulcerations in two siblings with FA. There was a rapid improvement and healing of ulcers after blood transfusions and increased haemoglobin levels. This may support the role of severe anaemia in oral ulcerations.
Url:
DOI: 10.1111/j.1365-263X.2004.00549.x
Links to Exploration step
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<front><div type="abstract">Summary. Fanconi's anaemia (FA) is an autosomal recessive disorder that is clinically characterized by aplastic anaemia, congenital malformations of the renal, cardiac, skeletal and skin structures, and an increased predisposition to malignancies. Patients with FA often present with bleeding and infection, which are symptoms related to thrombocytopenia and neutropenia. There are few reports of the oral manifestations of FA. We describe oral aphthous ulcerations in two siblings with FA. There was a rapid improvement and healing of ulcers after blood transfusions and increased haemoglobin levels. This may support the role of severe anaemia in oral ulcerations.</div>
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Fanconi's anaemia (FA) is an autosomal recessive disorder that is clinically characterized by aplastic anaemia, congenital malformations of the renal, cardiac, skeletal and skin structures, and an increased predisposition to malignancies. Patients with FA often present with bleeding and infection, which are symptoms related to thrombocytopenia and neutropenia. There are few reports of the oral manifestations of FA. We describe oral aphthous ulcerations in two siblings with FA. There was a rapid improvement and healing of ulcers after blood transfusions and increased haemoglobin levels. This may support the role of severe anaemia in oral ulcerations.</p>
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<correspondenceTo> G. Açikgöz, Ondokuz Mayis University, Faculty of Dentistry, Department of Periodontology, 55139 Kurupelit‐Samsun, Turkey. E‐mail: <email>gacikgoz@omu.edu.tr</email>
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<titleGroup><title type="main">Recurrent aphthous ulcers in Fanconi's anaemia: a case report</title>
<title type="shortAuthors"><i>F. Otan</i>
et al.</title>
<title type="short"><i>Recurrent aphthous ulcers in Fanconi's anaemia</i>
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Fanconi's anaemia (FA) is an autosomal recessive disorder that is clinically characterized by aplastic anaemia, congenital malformations of the renal, cardiac, skeletal and skin structures, and an increased predisposition to malignancies. Patients with FA often present with bleeding and infection, which are symptoms related to thrombocytopenia and neutropenia. There are few reports of the oral manifestations of FA. We describe oral aphthous ulcerations in two siblings with FA. There was a rapid improvement and healing of ulcers after blood transfusions and increased haemoglobin levels. This may support the role of severe anaemia in oral ulcerations.</p>
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