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Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report

Identifieur interne : 005845 ( Istex/Corpus ); précédent : 005844; suivant : 005846

Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report

Auteurs : Kunaal Dhingra ; Shobha Prakash

Source :

RBID : ISTEX:B1228A8C955C63C5C87B5A2587B0D19AF4D74C11

English descriptors

Abstract

doi: 10.1111/j.1741‐2358.2012.00624.x

Url:
DOI: 10.1111/j.1741-2358.2012.00624.x

Links to Exploration step

ISTEX:B1228A8C955C63C5C87B5A2587B0D19AF4D74C11

Le document en format XML

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<hi rend="italic">doi: 10.1111/j.1741‐2358.2012.00624.x</hi>
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<hi rend="bold">Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report</hi>
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<p>
<hi rend="bold">Background: </hi>
Drug‐influenced gingival overgrowth is an unaesthetic overgrowth of gingiva principally associated with intake of drugs like phenytoin, cyclosporin A and nifedipine. Its occurrence in both dentate and edentulous regions of oral cavity is poorly understood.</p>
<p>
<hi rend="bold">Objectives: </hi>
This report highlights clinical and histological description, aetiology and management of gingival overgrowth in a partially edentulous (non‐denture wearer) 60‐year‐old female patient with epilepsy on phenytoin and phenobarbital drugs from past 7 years.</p>
<p>
<hi rend="bold">Materials and methods: </hi>
Patient’s intraoral examination revealed lobulated and fibrotic consistency gingival overgrowth around teeth and on partially edentulous ridges of upper and lower arches along with generalised tooth mobility. Under medical consultation, full mouth extraction, surgical excision of overgrowth followed by complete denture rehabilitation and replacement of combination drugs with sodium valproate were accomplished.</p>
<p>
<hi rend="bold">Results: </hi>
Histologically, the lesion showed fibro‐epithelial hyperplasia. Clinical results after 6 months demonstrated almost complete resolution of gingival overgrowth.</p>
<p>
<hi rend="bold">Conclusion: </hi>
The findings of present case suggest that gingival overgrowth can occur even in partially edentulous ridges (not exposed to denture wear) that could be due to persistence of gingival overgrowth, which may not resolve completely following tooth extraction or occurs because of incorporation of specific subpopulation of gingival fibroblasts in alveolar ridge mucosa.</p>
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<i>Case Reports</i>
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<copyright>© 2012 The Gerodontology Society and John Wiley & Sons A/S</copyright>
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<correspondenceTo>Dr Kunaal Dhingra, Assistant Professor, Department of Periodontics, N.S.V.K Sri Venkateshwara Dental College, Bangalore, Karnataka, India. 
Tel.: +91 80 27803522 
Fax: +91 80 27828842 
E‐mail:
<email>kunaaldhingra@yahoo.co.in</email>
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<title type="main">Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report</title>
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<i>K. Dhingra, S. Prakash</i>
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<i>Gingival overgrowth in partially edentulous ridge</i>
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<keyword xml:id="k1">gingival overgrowth</keyword>
<keyword xml:id="k2">epilepsy</keyword>
<keyword xml:id="k3">partially edentulous</keyword>
<keyword xml:id="k4">phenytoin</keyword>
<keyword xml:id="k5">phenobarbital</keyword>
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<i>doi: 10.1111/j.1741‐2358.2012.00624.x</i>
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<b>Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report</b>
</p>
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<b>Background: </b>
Drug‐influenced gingival overgrowth is an unaesthetic overgrowth of gingiva principally associated with intake of drugs like phenytoin, cyclosporin A and nifedipine. Its occurrence in both dentate and edentulous regions of oral cavity is poorly understood.</p>
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<b>Objectives: </b>
This report highlights clinical and histological description, aetiology and management of gingival overgrowth in a partially edentulous (non‐denture wearer) 60‐year‐old female patient with epilepsy on phenytoin and phenobarbital drugs from past 7 years.</p>
<p>
<b>Materials and methods: </b>
Patient’s intraoral examination revealed lobulated and fibrotic consistency gingival overgrowth around teeth and on partially edentulous ridges of upper and lower arches along with generalised tooth mobility. Under medical consultation, full mouth extraction, surgical excision of overgrowth followed by complete denture rehabilitation and replacement of combination drugs with sodium valproate were accomplished.</p>
<p>
<b>Results: </b>
Histologically, the lesion showed fibro‐epithelial hyperplasia. Clinical results after 6 months demonstrated almost complete resolution of gingival overgrowth.</p>
<p>
<b>Conclusion: </b>
The findings of present case suggest that gingival overgrowth can occur even in partially edentulous ridges (not exposed to denture wear) that could be due to persistence of gingival overgrowth, which may not resolve completely following tooth extraction or occurs because of incorporation of specific subpopulation of gingival fibroblasts in alveolar ridge mucosa.</p>
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<abstract>Background:  Drug‐influenced gingival overgrowth is an unaesthetic overgrowth of gingiva principally associated with intake of drugs like phenytoin, cyclosporin A and nifedipine. Its occurrence in both dentate and edentulous regions of oral cavity is poorly understood.</abstract>
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<abstract>Materials and methods:  Patient’s intraoral examination revealed lobulated and fibrotic consistency gingival overgrowth around teeth and on partially edentulous ridges of upper and lower arches along with generalised tooth mobility. Under medical consultation, full mouth extraction, surgical excision of overgrowth followed by complete denture rehabilitation and replacement of combination drugs with sodium valproate were accomplished.</abstract>
<abstract>Results:  Histologically, the lesion showed fibro‐epithelial hyperplasia. Clinical results after 6 months demonstrated almost complete resolution of gingival overgrowth.</abstract>
<abstract>Conclusion:  The findings of present case suggest that gingival overgrowth can occur even in partially edentulous ridges (not exposed to denture wear) that could be due to persistence of gingival overgrowth, which may not resolve completely following tooth extraction or occurs because of incorporation of specific subpopulation of gingival fibroblasts in alveolar ridge mucosa.</abstract>
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