Helicobacter pylori in human oral cavity and stomach
Identifieur interne : 004E53 ( Istex/Corpus ); précédent : 004E52; suivant : 004E54Helicobacter pylori in human oral cavity and stomach
Auteurs : Ralf Bürgers ; Wulf Schneider-Brachert ; Udo Reischl ; Anke Behr ; Karl-Anton Hiller ; Norbert Lehn ; Gottfried Schmalz ; Stefan RuhlSource :
- European Journal of Oral Sciences [ 0909-8836 ] ; 2008-08.
English descriptors
- KwdEn :
- Amplicons, Assay, Clin, Clin microbiol, Colonization, Dental plaque, Detection limits, Gastric, Gastric biopsies, Helicobacter, Helicobacter pylori, Helicobacter pylori infection, Lightcycler, Microbiol, Oral cavity, Oral samples, Periodontal, Plaque, Polymerase, Polymerase chain reaction, Positive control, Present study, Primer, Primer sets, Pylori organisms, Pylorus, Sequencing, Subgingival.
- Teeft :
- Amplicons, Assay, Clin, Clin microbiol, Colonization, Dental plaque, Detection limits, Gastric, Gastric biopsies, Helicobacter, Helicobacter pylori, Helicobacter pylori infection, Lightcycler, Microbiol, Oral cavity, Oral samples, Periodontal, Plaque, Polymerase, Polymerase chain reaction, Positive control, Present study, Primer, Primer sets, Pylori organisms, Pylorus, Sequencing, Subgingival.
Abstract
The oral cavity has been suspected as an extra‐gastroduodenal reservoir for Helicobacter pylori infection and transmission, but conflicting evidence exists regarding the occurrence of H. pylori in the mouth, independently of stomach colonization. Ninety‐four gastric biopsy patients were analysed for the concurrent presence of H. pylori in the mouth and stomach. Samples were collected from different areas within the mouth and H. pylori DNA was amplified by the polymerase chain reaction (PCR) and verified by sequencing. Helicobacter pylori‐specific serology was performed, and stomach colonization was determined by culture. In addition, relevant dental and periodontal parameters, as well as general health parameters, were recorded. Helicobacter pylori was found in the stomach of 29 patients and in the oral cavity of 16 patients. In only six patients was the bacterium detected simultaneously in the stomach and mouth. Notably, the 10 patients in whom the bacterium was found solely in the mouth did not have serum antibodies to H. pylori. The occurrence of H. pylori in the mouth was found to be correlated neither to any general or oral health parameters, nor to any particular site of collection. This study shows that H. pylori can occur in the oral cavity independently of stomach colonization.
Url:
DOI: 10.1111/j.1600-0722.2008.00543.x
Links to Exploration step
ISTEX:9CDAF30C64C4D80B8CA76A5719F9648A6308173BLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Helicobacter pylori in human oral cavity and stomach</title><author><name sortKey="Burgers, Ralf" sort="Burgers, Ralf" uniqKey="Burgers R" first="Ralf" last="Bürgers">Ralf Bürgers</name><affiliation><mods:affiliation>Department of Operative Dentistry and Periodontology, Dental School</mods:affiliation></affiliation></author><author><name sortKey="Schneider Rachert, Wulf" sort="Schneider Rachert, Wulf" uniqKey="Schneider Rachert W" first="Wulf" last="Schneider-Brachert">Wulf Schneider-Brachert</name><affiliation><mods:affiliation>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Reischl, Udo" sort="Reischl, Udo" uniqKey="Reischl U" first="Udo" last="Reischl">Udo Reischl</name><affiliation><mods:affiliation>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Behr, Anke" sort="Behr, Anke" uniqKey="Behr A" first="Anke" last="Behr">Anke Behr</name><affiliation><mods:affiliation>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Hiller, Karl Nton" sort="Hiller, Karl Nton" uniqKey="Hiller K" first="Karl-Anton" last="Hiller">Karl-Anton Hiller</name><affiliation><mods:affiliation>Department of Operative Dentistry and Periodontology, Dental School</mods:affiliation></affiliation></author><author><name sortKey="Lehn, Norbert" sort="Lehn, Norbert" uniqKey="Lehn N" first="Norbert" last="Lehn">Norbert Lehn</name><affiliation><mods:affiliation>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Schmalz, Gottfried" sort="Schmalz, Gottfried" uniqKey="Schmalz G" first="Gottfried" last="Schmalz">Gottfried Schmalz</name><affiliation><mods:affiliation>Department of Operative Dentistry and Periodontology, Dental School</mods:affiliation></affiliation></author><author><name sortKey="Ruhl, Stefan" sort="Ruhl, Stefan" uniqKey="Ruhl S" first="Stefan" last="Ruhl">Stefan Ruhl</name><affiliation><mods:affiliation>Department of Operative Dentistry and Periodontology, Dental School</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:9CDAF30C64C4D80B8CA76A5719F9648A6308173B</idno><date when="2008" year="2008">2008</date><idno type="doi">10.1111/j.1600-0722.2008.00543.x</idno><idno type="url">https://api.istex.fr/document/9CDAF30C64C4D80B8CA76A5719F9648A6308173B/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">004E53</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">004E53</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main"><hi rend="italic">Helicobacter pylori</hi> in human oral cavity and stomach</title><author><name sortKey="Burgers, Ralf" sort="Burgers, Ralf" uniqKey="Burgers R" first="Ralf" last="Bürgers">Ralf Bürgers</name><affiliation><mods:affiliation>Department of Operative Dentistry and Periodontology, Dental School</mods:affiliation></affiliation></author><author><name sortKey="Schneider Rachert, Wulf" sort="Schneider Rachert, Wulf" uniqKey="Schneider Rachert W" first="Wulf" last="Schneider-Brachert">Wulf Schneider-Brachert</name><affiliation><mods:affiliation>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Reischl, Udo" sort="Reischl, Udo" uniqKey="Reischl U" first="Udo" last="Reischl">Udo Reischl</name><affiliation><mods:affiliation>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Behr, Anke" sort="Behr, Anke" uniqKey="Behr A" first="Anke" last="Behr">Anke Behr</name><affiliation><mods:affiliation>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Hiller, Karl Nton" sort="Hiller, Karl Nton" uniqKey="Hiller K" first="Karl-Anton" last="Hiller">Karl-Anton Hiller</name><affiliation><mods:affiliation>Department of Operative Dentistry and Periodontology, Dental School</mods:affiliation></affiliation></author><author><name sortKey="Lehn, Norbert" sort="Lehn, Norbert" uniqKey="Lehn N" first="Norbert" last="Lehn">Norbert Lehn</name><affiliation><mods:affiliation>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany</mods:affiliation></affiliation></author><author><name sortKey="Schmalz, Gottfried" sort="Schmalz, Gottfried" uniqKey="Schmalz G" first="Gottfried" last="Schmalz">Gottfried Schmalz</name><affiliation><mods:affiliation>Department of Operative Dentistry and Periodontology, Dental School</mods:affiliation></affiliation></author><author><name sortKey="Ruhl, Stefan" sort="Ruhl, Stefan" uniqKey="Ruhl S" first="Stefan" last="Ruhl">Stefan Ruhl</name><affiliation><mods:affiliation>Department of Operative Dentistry and Periodontology, Dental School</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">European Journal of Oral Sciences</title><title level="j" type="alt">EUROPEAN JOURNAL OF ORAL SCIENCES</title><idno type="ISSN">0909-8836</idno><idno type="eISSN">1600-0722</idno><imprint><biblScope unit="vol">116</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="297">297</biblScope><biblScope unit="page" to="304">304</biblScope><biblScope unit="page-count">8</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2008-08">2008-08</date></imprint><idno type="ISSN">0909-8836</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0909-8836</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Amplicons</term><term>Assay</term><term>Clin</term><term>Clin microbiol</term><term>Colonization</term><term>Dental plaque</term><term>Detection limits</term><term>Gastric</term><term>Gastric biopsies</term><term>Helicobacter</term><term>Helicobacter pylori</term><term>Helicobacter pylori infection</term><term>Lightcycler</term><term>Microbiol</term><term>Oral cavity</term><term>Oral samples</term><term>Periodontal</term><term>Plaque</term><term>Polymerase</term><term>Polymerase chain reaction</term><term>Positive control</term><term>Present study</term><term>Primer</term><term>Primer sets</term><term>Pylori organisms</term><term>Pylorus</term><term>Sequencing</term><term>Subgingival</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Amplicons</term><term>Assay</term><term>Clin</term><term>Clin microbiol</term><term>Colonization</term><term>Dental plaque</term><term>Detection limits</term><term>Gastric</term><term>Gastric biopsies</term><term>Helicobacter</term><term>Helicobacter pylori</term><term>Helicobacter pylori infection</term><term>Lightcycler</term><term>Microbiol</term><term>Oral cavity</term><term>Oral samples</term><term>Periodontal</term><term>Plaque</term><term>Polymerase</term><term>Polymerase chain reaction</term><term>Positive control</term><term>Present study</term><term>Primer</term><term>Primer sets</term><term>Pylori organisms</term><term>Pylorus</term><term>Sequencing</term><term>Subgingival</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The oral cavity has been suspected as an extra‐gastroduodenal reservoir for Helicobacter pylori infection and transmission, but conflicting evidence exists regarding the occurrence of H. pylori in the mouth, independently of stomach colonization. Ninety‐four gastric biopsy patients were analysed for the concurrent presence of H. pylori in the mouth and stomach. Samples were collected from different areas within the mouth and H. pylori DNA was amplified by the polymerase chain reaction (PCR) and verified by sequencing. Helicobacter pylori‐specific serology was performed, and stomach colonization was determined by culture. In addition, relevant dental and periodontal parameters, as well as general health parameters, were recorded. Helicobacter pylori was found in the stomach of 29 patients and in the oral cavity of 16 patients. In only six patients was the bacterium detected simultaneously in the stomach and mouth. Notably, the 10 patients in whom the bacterium was found solely in the mouth did not have serum antibodies to H. pylori. The occurrence of H. pylori in the mouth was found to be correlated neither to any general or oral health parameters, nor to any particular site of collection. This study shows that H. pylori can occur in the oral cavity independently of stomach colonization.</div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>pylorus</json:string><json:string>helicobacter</json:string><json:string>oral cavity</json:string><json:string>helicobacter pylori</json:string><json:string>lightcycler</json:string><json:string>gastric</json:string><json:string>polymerase</json:string><json:string>primer</json:string><json:string>dental plaque</json:string><json:string>sequencing</json:string><json:string>colonization</json:string><json:string>subgingival</json:string><json:string>clin</json:string><json:string>helicobacter pylori infection</json:string><json:string>amplicons</json:string><json:string>periodontal</json:string><json:string>detection limits</json:string><json:string>polymerase chain reaction</json:string><json:string>microbiol</json:string><json:string>present study</json:string><json:string>plaque</json:string><json:string>oral samples</json:string><json:string>clin microbiol</json:string><json:string>positive control</json:string><json:string>gastric biopsies</json:string><json:string>pylori organisms</json:string><json:string>primer sets</json:string><json:string>assay</json:string><json:string>body mass index</json:string><json:string>subgingival plaque</json:string><json:string>oral cavities</json:string><json:string>coccoid forms</json:string><json:string>pure organisms</json:string><json:string>pylori antibodies</json:string><json:string>pylori infection</json:string><json:string>high prevalence</json:string><json:string>stomach colonization</json:string><json:string>clin pathol</json:string><json:string>biopsy</json:string></teeft></keywords><author><json:item><name>Ralf Bürgers</name><affiliations><json:string>Department of Operative Dentistry and Periodontology, Dental School</json:string></affiliations></json:item><json:item><name>Wulf Schneider‐Brachert</name><affiliations><json:string>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany</json:string></affiliations></json:item><json:item><name>Udo Reischl</name><affiliations><json:string>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany</json:string></affiliations></json:item><json:item><name>Anke Behr</name><affiliations><json:string>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany</json:string></affiliations></json:item><json:item><name>Karl‐Anton Hiller</name><affiliations><json:string>Department of Operative Dentistry and Periodontology, Dental School</json:string></affiliations></json:item><json:item><name>Norbert Lehn</name><affiliations><json:string>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany</json:string></affiliations></json:item><json:item><name>Gottfried Schmalz</name><affiliations><json:string>Department of Operative Dentistry and Periodontology, Dental School</json:string></affiliations></json:item><json:item><name>Stefan Ruhl</name><affiliations><json:string>Department of Operative Dentistry and Periodontology, Dental School</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Helicobacter pylori</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>nested PCR</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>oral cavity</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>stomach</value></json:item></subject><articleId><json:string>EOS543</json:string></articleId><arkIstex>ark:/67375/WNG-V1S94L1H-P</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>The oral cavity has been suspected as an extra‐gastroduodenal reservoir for Helicobacter pylori infection and transmission, but conflicting evidence exists regarding the occurrence of H. pylori in the mouth, independently of stomach colonization. Ninety‐four gastric biopsy patients were analysed for the concurrent presence of H. pylori in the mouth and stomach. Samples were collected from different areas within the mouth and H. pylori DNA was amplified by the polymerase chain reaction (PCR) and verified by sequencing. Helicobacter pylori‐specific serology was performed, and stomach colonization was determined by culture. In addition, relevant dental and periodontal parameters, as well as general health parameters, were recorded. Helicobacter pylori was found in the stomach of 29 patients and in the oral cavity of 16 patients. In only six patients was the bacterium detected simultaneously in the stomach and mouth. Notably, the 10 patients in whom the bacterium was found solely in the mouth did not have serum antibodies to H. pylori. The occurrence of H. pylori in the mouth was found to be correlated neither to any general or oral health parameters, nor to any particular site of collection. This study shows that H. pylori can occur in the oral cavity independently of stomach colonization.</abstract><qualityIndicators><score>9.304</score><pdfWordCount>5646</pdfWordCount><pdfCharCount>34941</pdfCharCount><pdfVersion>1.3</pdfVersion><pdfPageCount>8</pdfPageCount><pdfPageSize>595.276 x 799.37 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractWordCount>192</abstractWordCount><abstractCharCount>1307</abstractCharCount><keywordCount>4</keywordCount></qualityIndicators><title>Helicobacter pylori in human oral cavity and stomach</title><pmid><json:string>18705796</json:string></pmid><genre><json:string>article</json:string></genre><host><title>European Journal of Oral Sciences</title><language><json:string>unknown</json:string></language><doi><json:string>10.1111/(ISSN)1600-0722</json:string></doi><issn><json:string>0909-8836</json:string></issn><eissn><json:string>1600-0722</json:string></eissn><publisherId><json:string>EOS</json:string></publisherId><volume>116</volume><issue>4</issue><pages><first>297</first><last>304</last><total>8</total></pages><genre><json:string>journal</json:string></genre></host><namedEntities><unitex><date><json:string>16S</json:string><json:string>2008</json:string><json:string>1980s</json:string></date><geogName></geogName><orgName><json:string>Roche Diagnostics, Mannheim, Germany</json:string><json:string>Umea University, Sweden</json:string><json:string>Qiagen</json:string><json:string>Germany Stefan Ruhl, Department of Oral Biology, School of Dental Medicine, State University</json:string><json:string>Gastroenterology</json:string><json:string>Institute of Medical Microbiology and Hygiene</json:string><json:string>University of Regensburg</json:string></orgName><orgName_funder></orgName_funder><orgName_provider></orgName_provider><persName><json:string>Stomach</json:string><json:string>Wulf SchneiderBrachert</json:string><json:string>R. Kellner</json:string><json:string>H. Worliczek</json:string><json:string>Holger Melzl</json:string><json:string>Foster Hall</json:string><json:string>Thomas Boren</json:string><json:string>Karl-Anton Hiller</json:string><json:string>Stefan Ruhl</json:string><json:string>Informed</json:string><json:string>S. Weidenhiller</json:string><json:string>Frank Scannapieco</json:string><json:string>Dr</json:string><json:string>A. Occurrence</json:string><json:string>Markus Bollwein</json:string><json:string>Ethics Boards</json:string><json:string>Norbert Lehn</json:string><json:string>Steven Gill</json:string></persName><placeName><json:string>IL</json:string><json:string>Buffalo</json:string><json:string>Berlin</json:string><json:string>Foster City</json:string><json:string>Columbia</json:string><json:string>Germany</json:string><json:string>Munich</json:string><json:string>NY</json:string><json:string>Heidelberg</json:string><json:string>UK</json:string><json:string>Regensburg</json:string><json:string>Eppendorf</json:string><json:string>Hamburg</json:string><json:string>USA</json:string><json:string>Chicago</json:string><json:string>CA</json:string><json:string>France</json:string></placeName><ref_url></ref_url><ref_bibl></ref_bibl><bibl></bibl></unitex></namedEntities><ark><json:string>ark:/67375/WNG-V1S94L1H-P</json:string></ark><categories><wos><json:string>1 - science</json:string><json:string>2 - dentistry, oral surgery & medicine</json:string></wos><scienceMetrix><json:string>1 - health sciences</json:string><json:string>2 - clinical medicine</json:string><json:string>3 - dentistry</json:string></scienceMetrix><scopus><json:string>1 - Health Sciences</json:string><json:string>2 - Dentistry</json:string><json:string>3 - General Dentistry</json:string></scopus><inist><json:string>1 - sciences appliquees, technologies et medecines</json:string><json:string>2 - sciences biologiques et medicales</json:string><json:string>3 - sciences medicales</json:string></inist></categories><publicationDate>2008</publicationDate><copyrightDate>2008</copyrightDate><doi><json:string>10.1111/j.1600-0722.2008.00543.x</json:string></doi><id>9CDAF30C64C4D80B8CA76A5719F9648A6308173B</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/9CDAF30C64C4D80B8CA76A5719F9648A6308173B/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/9CDAF30C64C4D80B8CA76A5719F9648A6308173B/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/9CDAF30C64C4D80B8CA76A5719F9648A6308173B/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main"><hi rend="italic">Helicobacter pylori</hi> in human oral cavity and stomach</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><availability><licence>© 2008 The Authors. Journal compilation © 2008 Eur J Oral Sci</licence></availability><date type="published" when="2008-08"></date></publicationStmt><notesStmt><note type="content-type" subtype="article" source="article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="article"><analytic><title level="a" type="main"><hi rend="italic">Helicobacter pylori</hi> in human oral cavity and stomach</title><title level="a" type="short">Helicobacter pylori in mouth and stomach</title><author xml:id="author-0000"><persName><forename type="first">Ralf</forename><surname>Bürgers</surname></persName><affiliation>Department of Operative Dentistry and Periodontology, Dental School</affiliation></author><author xml:id="author-0001"><persName><forename type="first">Wulf</forename><surname>Schneider‐Brachert</surname></persName><affiliation>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany<address><country key="DE"></country></address></affiliation></author><author xml:id="author-0002"><persName><forename type="first">Udo</forename><surname>Reischl</surname></persName><affiliation>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany<address><country key="DE"></country></address></affiliation></author><author xml:id="author-0003"><persName><forename type="first">Anke</forename><surname>Behr</surname></persName><affiliation>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany<address><country key="DE"></country></address></affiliation></author><author xml:id="author-0004"><persName><forename type="first">Karl‐Anton</forename><surname>Hiller</surname></persName><affiliation>Department of Operative Dentistry and Periodontology, Dental School</affiliation></author><author xml:id="author-0005"><persName><forename type="first">Norbert</forename><surname>Lehn</surname></persName><affiliation>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany<address><country key="DE"></country></address></affiliation></author><author xml:id="author-0006"><persName><forename type="first">Gottfried</forename><surname>Schmalz</surname></persName><affiliation>Department of Operative Dentistry and Periodontology, Dental School</affiliation></author><author xml:id="author-0007"><persName><forename type="first">Stefan</forename><surname>Ruhl</surname></persName><affiliation>Department of Operative Dentistry and Periodontology, Dental School</affiliation></author><idno type="istex">9CDAF30C64C4D80B8CA76A5719F9648A6308173B</idno><idno type="ark">ark:/67375/WNG-V1S94L1H-P</idno><idno type="DOI">10.1111/j.1600-0722.2008.00543.x</idno><idno type="unit">EOS543</idno><idno type="toTypesetVersion">file:EOS.EOS543.pdf</idno></analytic><monogr><title level="j" type="main">European Journal of Oral Sciences</title><title level="j" type="alt">EUROPEAN JOURNAL OF ORAL SCIENCES</title><idno type="pISSN">0909-8836</idno><idno type="eISSN">1600-0722</idno><idno type="book-DOI">10.1111/(ISSN)1600-0722</idno><idno type="book-part-DOI">10.1111/eos.2008.116.issue-4</idno><idno type="product">EOS</idno><idno type="publisherDivision">ST</idno><imprint><biblScope unit="vol">116</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="297">297</biblScope><biblScope unit="page" to="304">304</biblScope><biblScope unit="page-count">8</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2008-08"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><abstract xml:lang="en" style="main"><p>The oral cavity has been suspected as an extra‐gastroduodenal reservoir for <hi rend="italic">Helicobacter pylori</hi> infection and transmission, but conflicting evidence exists regarding the occurrence of <hi rend="italic">H. pylori</hi> in the mouth, independently of stomach colonization. Ninety‐four gastric biopsy patients were analysed for the concurrent presence of <hi rend="italic">H. pylori</hi> in the mouth and stomach. Samples were collected from different areas within the mouth and <hi rend="italic">H. pylori</hi> DNA was amplified by the polymerase chain reaction (PCR) and verified by sequencing. <hi rend="italic">Helicobacter pylori</hi>‐specific serology was performed, and stomach colonization was determined by culture. In addition, relevant dental and periodontal parameters, as well as general health parameters, were recorded. <hi rend="italic">Helicobacter pylori</hi> was found in the stomach of 29 patients and in the oral cavity of 16 patients. In only six patients was the bacterium detected simultaneously in the stomach and mouth. Notably, the 10 patients in whom the bacterium was found solely in the mouth did not have serum antibodies to <hi rend="italic">H. pylori</hi>. The occurrence of <hi rend="italic">H. pylori</hi> in the mouth was found to be correlated neither to any general or oral health parameters, nor to any particular site of collection. This study shows that <hi rend="italic">H. pylori</hi> can occur in the oral cavity independently of stomach colonization.</p></abstract><textClass><keywords xml:lang="en"><term xml:id="k1"><hi rend="italic">Helicobacter pylori</hi></term><term xml:id="k2">nested PCR</term><term xml:id="k3">oral cavity</term><term xml:id="k4">stomach</term></keywords><keywords rend="tocHeading1"><term>Original articles</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/9CDAF30C64C4D80B8CA76A5719F9648A6308173B/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Publishing Ltd</publisherName><publisherLoc>Oxford, UK</publisherLoc></publisherInfo><doi origin="wiley" registered="yes">10.1111/(ISSN)1600-0722</doi><issn type="print">0909-8836</issn><issn type="electronic">1600-0722</issn><idGroup><id type="product" value="EOS"></id><id type="publisherDivision" value="ST"></id></idGroup><titleGroup><title type="main" sort="EUROPEAN JOURNAL OF ORAL SCIENCES">European Journal of Oral Sciences</title></titleGroup></publicationMeta><publicationMeta level="part" position="08004"><doi origin="wiley">10.1111/eos.2008.116.issue-4</doi><numberingGroup><numbering type="journalVolume" number="116">116</numbering><numbering type="journalIssue" number="4">4</numbering></numberingGroup><coverDate startDate="2008-08">August 2008</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="2" status="forIssue"><doi origin="wiley">10.1111/j.1600-0722.2008.00543.x</doi><idGroup><id type="unit" value="EOS543"></id></idGroup><countGroup><count type="pageTotal" number="8"></count></countGroup><titleGroup><title type="tocHeading1">Original articles</title></titleGroup><copyright>© 2008 The Authors. Journal compilation © 2008 Eur J Oral Sci</copyright><eventGroup><event type="firstOnline" date="2008-07-09"></event><event type="publishedOnlineFinalForm" date="2008-07-09"></event><event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:2.3.2 mode:FullText source:FullText result:FullText" date="2010-03-06"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-24"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-16"></event></eventGroup><numberingGroup><numbering type="pageFirst" number="297">297</numbering><numbering type="pageLast" number="304">304</numbering></numberingGroup><correspondenceTo>Stefan Ruhl, Department of Oral Biology, School of Dental Medicine, State University at Buffalo, 3435 Main Street, Foster Hall, Room 213A, Buffalo, NY 14214‐3092, USA Telefax: +1–716–8293942
E‐mail: <email>shruhl@buffalo.edu</email></correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:EOS.EOS543.pdf"></link></linkGroup></publicationMeta><contentMeta><unparsedEditorialHistory>Accepted for publication April 2008</unparsedEditorialHistory><countGroup><count type="figureTotal" number="1"></count><count type="tableTotal" number="3"></count></countGroup><titleGroup><title type="main"><i>Helicobacter pylori</i> in human oral cavity and stomach</title><title type="shortAuthors"><i>Bürgers</i> et al.</title><title type="short">Helicobacter pylori <i>in mouth and stomach</i></title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1"><personName><givenNames>Ralf</givenNames><familyName>Bürgers</familyName></personName></creator><creator creatorRole="author" xml:id="cr2" affiliationRef="#a2"><personName><givenNames>Wulf</givenNames><familyName>Schneider‐Brachert</familyName></personName></creator><creator creatorRole="author" xml:id="cr3" affiliationRef="#a2"><personName><givenNames>Udo</givenNames><familyName>Reischl</familyName></personName></creator><creator creatorRole="author" xml:id="cr4" affiliationRef="#a2"><personName><givenNames>Anke</givenNames><familyName>Behr</familyName></personName></creator><creator creatorRole="author" xml:id="cr5" affiliationRef="#a1"><personName><givenNames>Karl‐Anton</givenNames><familyName>Hiller</familyName></personName></creator><creator creatorRole="author" xml:id="cr6" affiliationRef="#a2"><personName><givenNames>Norbert</givenNames><familyName>Lehn</familyName></personName></creator><creator creatorRole="author" xml:id="cr7" affiliationRef="#a1"><personName><givenNames>Gottfried</givenNames><familyName>Schmalz</familyName></personName></creator><creator creatorRole="author" xml:id="cr8" affiliationRef="#a1"><personName><givenNames>Stefan</givenNames><familyName>Ruhl</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="a1"><unparsedAffiliation>Department of Operative Dentistry and Periodontology, Dental School</unparsedAffiliation></affiliation><affiliation xml:id="a2" countryCode="DE"><unparsedAffiliation>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en"><keyword xml:id="k1"><i>Helicobacter pylori</i></keyword><keyword xml:id="k2">nested PCR</keyword><keyword xml:id="k3">oral cavity</keyword><keyword xml:id="k4">stomach</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><!--
Bürgers R, Schneider-Brachert W, Reischl U, Behr A, Hiller K-A, Lehn N, Schmalz G, Ruhl S. Helicobacter pylori in human oral cavity and stomach. Eur J Oral Sci 2008; 116: 297–304. © 2008 The Authors. Journal compilation © 2008 Eur J Oral Sci
--><p>The oral cavity has been suspected as an extra‐gastroduodenal reservoir for <i>Helicobacter pylori</i> infection and transmission, but conflicting evidence exists regarding the occurrence of <i>H. pylori</i> in the mouth, independently of stomach colonization. Ninety‐four gastric biopsy patients were analysed for the concurrent presence of <i>H. pylori</i> in the mouth and stomach. Samples were collected from different areas within the mouth and <i>H. pylori</i> DNA was amplified by the polymerase chain reaction (PCR) and verified by sequencing. <i>Helicobacter pylori</i>‐specific serology was performed, and stomach colonization was determined by culture. In addition, relevant dental and periodontal parameters, as well as general health parameters, were recorded. <i>Helicobacter pylori</i> was found in the stomach of 29 patients and in the oral cavity of 16 patients. In only six patients was the bacterium detected simultaneously in the stomach and mouth. Notably, the 10 patients in whom the bacterium was found solely in the mouth did not have serum antibodies to <i>H. pylori</i>. The occurrence of <i>H. pylori</i> in the mouth was found to be correlated neither to any general or oral health parameters, nor to any particular site of collection. This study shows that <i>H. pylori</i> can occur in the oral cavity independently of stomach colonization.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Helicobacter pylori in human oral cavity and stomach</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Helicobacter pylori in mouth and stomach</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Helicobacter pylori in human oral cavity and stomach</title></titleInfo><name type="personal"><namePart type="given">Ralf</namePart><namePart type="family">Bürgers</namePart><affiliation>Department of Operative Dentistry and Periodontology, Dental School</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Wulf</namePart><namePart type="family">Schneider‐Brachert</namePart><affiliation>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Udo</namePart><namePart type="family">Reischl</namePart><affiliation>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Anke</namePart><namePart type="family">Behr</namePart><affiliation>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Karl‐Anton</namePart><namePart type="family">Hiller</namePart><affiliation>Department of Operative Dentistry and Periodontology, Dental School</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Norbert</namePart><namePart type="family">Lehn</namePart><affiliation>Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Gottfried</namePart><namePart type="family">Schmalz</namePart><affiliation>Department of Operative Dentistry and Periodontology, Dental School</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Stefan</namePart><namePart type="family">Ruhl</namePart><affiliation>Department of Operative Dentistry and Periodontology, Dental School</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">2008-08</dateIssued><edition>Accepted for publication April 2008</edition><copyrightDate encoding="w3cdtf">2008</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="figures">1</extent><extent unit="tables">3</extent></physicalDescription><abstract lang="en">The oral cavity has been suspected as an extra‐gastroduodenal reservoir for Helicobacter pylori infection and transmission, but conflicting evidence exists regarding the occurrence of H. pylori in the mouth, independently of stomach colonization. Ninety‐four gastric biopsy patients were analysed for the concurrent presence of H. pylori in the mouth and stomach. Samples were collected from different areas within the mouth and H. pylori DNA was amplified by the polymerase chain reaction (PCR) and verified by sequencing. Helicobacter pylori‐specific serology was performed, and stomach colonization was determined by culture. In addition, relevant dental and periodontal parameters, as well as general health parameters, were recorded. Helicobacter pylori was found in the stomach of 29 patients and in the oral cavity of 16 patients. In only six patients was the bacterium detected simultaneously in the stomach and mouth. Notably, the 10 patients in whom the bacterium was found solely in the mouth did not have serum antibodies to H. pylori. The occurrence of H. pylori in the mouth was found to be correlated neither to any general or oral health parameters, nor to any particular site of collection. This study shows that H. pylori can occur in the oral cavity independently of stomach colonization.</abstract><subject lang="en"><genre>keywords</genre><topic>Helicobacter pylori</topic><topic>nested PCR</topic><topic>oral cavity</topic><topic>stomach</topic></subject><relatedItem type="host"><titleInfo><title>European Journal of Oral Sciences</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><identifier type="ISSN">0909-8836</identifier><identifier type="eISSN">1600-0722</identifier><identifier type="DOI">10.1111/(ISSN)1600-0722</identifier><identifier type="PublisherID">EOS</identifier><part><date>2008</date><detail type="volume"><caption>vol.</caption><number>116</number></detail><detail type="issue"><caption>no.</caption><number>4</number></detail><extent unit="pages"><start>297</start><end>304</end><total>8</total></extent></part></relatedItem><identifier type="istex">9CDAF30C64C4D80B8CA76A5719F9648A6308173B</identifier><identifier type="ark">ark:/67375/WNG-V1S94L1H-P</identifier><identifier type="DOI">10.1111/j.1600-0722.2008.00543.x</identifier><identifier type="ArticleID">EOS543</identifier><accessCondition type="use and reproduction" contentType="copyright">© 2008 The Authors. Journal compilation © 2008 Eur J Oral Sci</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-L0C46X92-X">wiley</recordContentSource><recordOrigin>Blackwell Publishing Ltd</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/document/9CDAF30C64C4D80B8CA76A5719F9648A6308173B/metadata/json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004E53 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 004E53 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= EdenteV2
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:9CDAF30C64C4D80B8CA76A5719F9648A6308173B
|texte= Helicobacter pylori in human oral cavity and stomach
}}
| This area was generated with Dilib version V0.6.32. |  |