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Osteonecrosis of the jaws in periodontal patients with a history of bisphosphonates treatment

Identifieur interne : 002F17 ( Istex/Checkpoint ); précédent : 002F16; suivant : 002F18

Osteonecrosis of the jaws in periodontal patients with a history of bisphosphonates treatment

Auteurs : G. Ficarra ; F. Beninati ; I. Rubino ; A. Vannucchi ; G. Longo ; P. Tonelli ; G. Pini Prato [Italie]

Source :

RBID : ISTEX:CB6094CCD43FA6D433786540130DB5654FB2BE3A

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English descriptors

Abstract

Background/Aim: Osteonecrosis of the jaws is being increasingly reported in patients with bone metastasis from a variety of solid tumours and disseminated multiple myeloma receiving intra‐venous bisphosphonates. The signs and symptoms that may occur before the appearance of clinical evident osteonecrosis include changes in the health of periodontal tissues, non‐healing mucosal ulcers, loose teeth and unexplained soft‐tissue infection. A series of nine periodontally involving patients showing osteonecrosis of the jaws that appeared following the intra‐venous use of bisphosphonates is reported.

Url:
DOI: 10.1111/j.1600-051X.2005.00842.x


Affiliations:


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ISTEX:CB6094CCD43FA6D433786540130DB5654FB2BE3A

Le document en format XML

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<name sortKey="Longo, G" sort="Longo, G" uniqKey="Longo G" first="G." last="Longo">G. Longo</name>
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<name sortKey="Tonelli, P" sort="Tonelli, P" uniqKey="Tonelli P" first="P." last="Tonelli">P. Tonelli</name>
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<wicri:regionArea>Department of Periodontology, University of Florence and Azienda Ospedaliera‐Universitaria Careggi, Florence</wicri:regionArea>
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<title level="j" type="main">Journal of Clinical Periodontology</title>
<title level="j" type="alt">JOURNAL OF CLINICAL PERIODONTOLOGY</title>
<idno type="ISSN">0303-6979</idno>
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<term>Bisphosphonate</term>
<term>Bisphosphonate treatment</term>
<term>Bisphosphonates</term>
<term>Bisphosphonates therapy</term>
<term>Bone metastasis</term>
<term>Bone necrosis</term>
<term>Bone sequestra</term>
<term>Breast cancer</term>
<term>Cancer chemotherapy</term>
<term>Clinical oncology</term>
<term>Consecutive patients</term>
<term>Conservative debridement</term>
<term>Cyclic</term>
<term>Debridement</term>
<term>England journal</term>
<term>Haematological neoplasms</term>
<term>Intravenous bisphosphonates</term>
<term>Lesion</term>
<term>Local irrigation</term>
<term>Loose teeth</term>
<term>Mandible</term>
<term>Maxillofacial</term>
<term>Maxillofacial surgery</term>
<term>Metastasis</term>
<term>Metastatic</term>
<term>Metastatic bone disease</term>
<term>Migliorati</term>
<term>Mucosal ulcers</term>
<term>Multiple myeloma</term>
<term>Myeloma</term>
<term>Osteonecrosis</term>
<term>Pamidronate</term>
<term>Periodontal</term>
<term>Periodontal patients</term>
<term>Periodontal tissues</term>
<term>Ruggiero</term>
<term>Sequestrum</term>
<term>Tooth extraction</term>
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<term>Zoledronate</term>
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<term>American society</term>
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<term>Bisphosphonates</term>
<term>Bisphosphonates therapy</term>
<term>Bone metastasis</term>
<term>Bone necrosis</term>
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<term>Breast cancer</term>
<term>Cancer chemotherapy</term>
<term>Clinical oncology</term>
<term>Consecutive patients</term>
<term>Conservative debridement</term>
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<term>England journal</term>
<term>Haematological neoplasms</term>
<term>Intravenous bisphosphonates</term>
<term>Lesion</term>
<term>Local irrigation</term>
<term>Loose teeth</term>
<term>Mandible</term>
<term>Maxillofacial</term>
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<term>Multiple myeloma</term>
<term>Myeloma</term>
<term>Osteonecrosis</term>
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<div type="abstract">Background/Aim: Osteonecrosis of the jaws is being increasingly reported in patients with bone metastasis from a variety of solid tumours and disseminated multiple myeloma receiving intra‐venous bisphosphonates. The signs and symptoms that may occur before the appearance of clinical evident osteonecrosis include changes in the health of periodontal tissues, non‐healing mucosal ulcers, loose teeth and unexplained soft‐tissue infection. A series of nine periodontally involving patients showing osteonecrosis of the jaws that appeared following the intra‐venous use of bisphosphonates is reported.</div>
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<name sortKey="Longo, G" sort="Longo, G" uniqKey="Longo G" first="G." last="Longo">G. Longo</name>
<name sortKey="Rubino, I" sort="Rubino, I" uniqKey="Rubino I" first="I." last="Rubino">I. Rubino</name>
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