Effects of bisphosphonates on tooth eruption in children with osteogenesis imperfecta
Identifieur interne : 000181 ( France/Analysis ); précédent : 000180; suivant : 000182Effects of bisphosphonates on tooth eruption in children with osteogenesis imperfecta
Auteurs : Agnès Kamoun-Goldrat [France] ; Danielle Ginisty [France] ; Martine Le Merrer [France]Source :
- European Journal of Oral Sciences [ 0909-8836 ] ; 2008-06.
English descriptors
- KwdEn :
- Acellular cementum, Association francophone belge, Biol, Bisphosphonate, Bisphosphonate therapy, Bisphosphonate therapy delays tooth eruption, Bisphosphonates, Bone fragility, Bone miner, Bone resorption, Calcif tissue, Clinical examination, Craniofac genet, Dental development, Dental maturity, Dentinogenesis imperfecta, Eruption, Imperfecta, Journal compilation, Normal rats, Oral pathol, Oral surg, Osteoclast, Osteogenesis, Osteogenesis imperfecta, Osteogenesis imperfecta patients, Osteopetrotic rodents, Permanent dentition, Permanent teeth, Previous study, Primary teeth, Protein prenylation, Resorb bone, Resorption, Scanning electron microscopy, Teeth eruption, Tooth counts, Tooth emergence, Tooth eruption.
- Teeft :
- Acellular cementum, Association francophone belge, Biol, Bisphosphonate, Bisphosphonate therapy, Bisphosphonate therapy delays tooth eruption, Bisphosphonates, Bone fragility, Bone miner, Bone resorption, Calcif tissue, Clinical examination, Craniofac genet, Dental development, Dental maturity, Dentinogenesis imperfecta, Eruption, Imperfecta, Journal compilation, Normal rats, Oral pathol, Oral surg, Osteoclast, Osteogenesis, Osteogenesis imperfecta, Osteogenesis imperfecta patients, Osteopetrotic rodents, Permanent dentition, Permanent teeth, Previous study, Primary teeth, Protein prenylation, Resorb bone, Resorption, Scanning electron microscopy, Teeth eruption, Tooth counts, Tooth emergence, Tooth eruption.
Abstract
Bisphosphonates are currently used in the therapy of osteogenesis imperfecta (OI) to decrease the bone fragility observed in OI patients. Bisphosphonate therapy delays tooth eruption in rats. The aim of this study was to determine whether or not bisphosphonate therapy delays tooth eruption in children. The clinical emergence of teeth was observed and the calculated dental age and the number of delayed teeth were determined for 33 OI patients treated with bisphosphonates and for strictly gender‐ and age‐matched controls. There were significant differences between bisphosphonate‐treated patients and controls for calculated dental age and number of delayed teeth. Bisphosphonate therapy was associated with a mean delay of 1.67 yr in tooth eruption in children with OI.
Url:
DOI: 10.1111/j.1600-0722.2008.00529.x
Affiliations:
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patients</term><term>Osteopetrotic rodents</term><term>Permanent dentition</term><term>Permanent teeth</term><term>Previous study</term><term>Primary teeth</term><term>Protein prenylation</term><term>Resorb bone</term><term>Resorption</term><term>Scanning electron microscopy</term><term>Teeth eruption</term><term>Tooth counts</term><term>Tooth emergence</term><term>Tooth eruption</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Acellular cementum</term><term>Association francophone belge</term><term>Biol</term><term>Bisphosphonate</term><term>Bisphosphonate therapy</term><term>Bisphosphonate therapy delays tooth eruption</term><term>Bisphosphonates</term><term>Bone fragility</term><term>Bone miner</term><term>Bone resorption</term><term>Calcif tissue</term><term>Clinical examination</term><term>Craniofac genet</term><term>Dental development</term><term>Dental maturity</term><term>Dentinogenesis imperfecta</term><term>Eruption</term><term>Imperfecta</term><term>Journal 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Bisphosphonate therapy delays tooth eruption in rats. The aim of this study was to determine whether or not bisphosphonate therapy delays tooth eruption in children. The clinical emergence of teeth was observed and the calculated dental age and the number of delayed teeth were determined for 33 OI patients treated with bisphosphonates and for strictly gender‐ and age‐matched controls. There were significant differences between bisphosphonate‐treated patients and controls for calculated dental age and number of delayed teeth. Bisphosphonate therapy was associated with a mean delay of 1.67 yr in tooth eruption in children with OI.</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Île-de-France</li></region><settlement><li>Paris</li></settlement></list><tree><country name="France"><region name="Île-de-France"><name sortKey="Kamoun Oldrat, Agnes" sort="Kamoun Oldrat, Agnes" uniqKey="Kamoun Oldrat A" first="Agnès" last="Kamoun-Goldrat">Agnès Kamoun-Goldrat</name></region><name sortKey="Ginisty, Danielle" sort="Ginisty, Danielle" uniqKey="Ginisty D" first="Danielle" last="Ginisty">Danielle Ginisty</name><name sortKey="Merrer, Martine Le" sort="Merrer, Martine Le" uniqKey="Merrer M" first="Martine Le" last="Merrer">Martine Le Merrer</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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