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Guided Bone Regeneration Using Cyanoacrylate-Combined Calcium Phosphate in a Dehiscence Defect: A Histologic Study in Dogs

Identifieur interne : 000052 ( PascalFrancis/Corpus ); précédent : 000051; suivant : 000053

Guided Bone Regeneration Using Cyanoacrylate-Combined Calcium Phosphate in a Dehiscence Defect: A Histologic Study in Dogs

Auteurs : Jung-Seok Lee ; Seung-Hee Ko ; Young-Taek Kim ; Ui-Won Jung ; Seong-Ho Choi

Source :

RBID : Pascal:12-0354869

Descripteurs français

English descriptors

Abstract

Purpose: This study evaluated the effects of cyanoacrylate-combined calcium phosphate (CCP) as a candidate for a barrier membrane substitute in guided bone regeneration and the space maintenance capability of CCP placed in a dehiscence defect model. Materials and Methods: Six standardized dehiscence defects (5 × 3 mm, height × width) around dental implants were created on unilateral edentulous ridges in 5 dogs, where each defect was treated with sham surgery, biphasic calcium phosphate (BCP), CCP, barrier membrane (MEM), BCP + MEM, and CCP + MEM. The animals were sacrificed after an 8-week healing interval for histologic and histometric analyses. Results: The BCP and CCP sites showed increased bone formation compared with the control sites, although incomplete defect resolution occurred; bone regeneration heights (area) averaged 3.52 ± 0.69 mm (4.94 ± 2.59 mm2), 3.51 ± 0.16 mm (4.10 ± 1.99 mm2), and 1.53 ± 0.42 mm (1.01 ± 0.74 mm2) for the BCP, CCP, and control sites, respectively. All the MEM sites showed more bone formation compared with the sites that received the same biomaterials without a MEM, and the BCP + MEM and CCP + MEM sites showed extensive bone formation within the defect and on top of the implant; the bone regeneration heights (area) averaged 3.96 ± 2.86 mm (12.46 ± 11.61 mm2), 5.45 ± 0.25 mm (11.63 ± 1.97 mm2), and 2.62 ± 0.27 mm (3.43 ± 0.98 mm2) for the BCP + MEM, CCP + MEM, and MEM sites, respectively. Conclusions: CCP can be a good scaffold for supporting an MEM as opposed to acting as a substitute for the MEM in guided bone regeneration.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0278-2391
A02 01      @0 JOMSDA
A03   1    @0 J. oral maxillofac. surg.
A05       @2 70
A06       @2 9
A08 01  1  ENG  @1 Guided Bone Regeneration Using Cyanoacrylate-Combined Calcium Phosphate in a Dehiscence Defect: A Histologic Study in Dogs
A11 01  1    @1 LEE (Jung-Seok)
A11 02  1    @1 KO (Seung-Hee)
A11 03  1    @1 KIM (Young-Taek)
A11 04  1    @1 JUNG (Ui-Won)
A11 05  1    @1 CHOI (Seong-Ho)
A14 01      @1 Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University @2 Seoul @3 KOR @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 4 aut. @Z 5 aut.
A20       @1 2070-2079
A21       @1 2012
A23 01      @0 ENG
A43 01      @1 INIST @2 3005 @5 354000504462940100
A44       @0 0000 @1 © 2012 INIST-CNRS. All rights reserved.
A45       @0 39 ref.
A47 01  1    @0 12-0354869
A60       @1 P
A61       @0 A
A64 01  1    @0 Journal of oral and maxillofacial surgery
A66 01      @0 USA
C01 01    ENG  @0 Purpose: This study evaluated the effects of cyanoacrylate-combined calcium phosphate (CCP) as a candidate for a barrier membrane substitute in guided bone regeneration and the space maintenance capability of CCP placed in a dehiscence defect model. Materials and Methods: Six standardized dehiscence defects (5 × 3 mm, height × width) around dental implants were created on unilateral edentulous ridges in 5 dogs, where each defect was treated with sham surgery, biphasic calcium phosphate (BCP), CCP, barrier membrane (MEM), BCP + MEM, and CCP + MEM. The animals were sacrificed after an 8-week healing interval for histologic and histometric analyses. Results: The BCP and CCP sites showed increased bone formation compared with the control sites, although incomplete defect resolution occurred; bone regeneration heights (area) averaged 3.52 ± 0.69 mm (4.94 ± 2.59 mm2), 3.51 ± 0.16 mm (4.10 ± 1.99 mm2), and 1.53 ± 0.42 mm (1.01 ± 0.74 mm2) for the BCP, CCP, and control sites, respectively. All the MEM sites showed more bone formation compared with the sites that received the same biomaterials without a MEM, and the BCP + MEM and CCP + MEM sites showed extensive bone formation within the defect and on top of the implant; the bone regeneration heights (area) averaged 3.96 ± 2.86 mm (12.46 ± 11.61 mm2), 5.45 ± 0.25 mm (11.63 ± 1.97 mm2), and 2.62 ± 0.27 mm (3.43 ± 0.98 mm2) for the BCP + MEM, CCP + MEM, and MEM sites, respectively. Conclusions: CCP can be a good scaffold for supporting an MEM as opposed to acting as a substitute for the MEM in guided bone regeneration.
C02 01  X    @0 002B10
C03 01  X  FRE  @0 Chirurgie @5 04
C03 01  X  ENG  @0 Surgery @5 04
C03 01  X  SPA  @0 Cirugía @5 04
C03 02  X  FRE  @0 Guidage @5 07
C03 02  X  ENG  @0 Guidance @5 07
C03 02  X  SPA  @0 Guiado @5 07
C03 03  X  FRE  @0 Os @5 08
C03 03  X  ENG  @0 Bone @5 08
C03 03  X  SPA  @0 Hueso @5 08
C03 04  X  FRE  @0 Régénération @5 09
C03 04  X  ENG  @0 Regeneration @5 09
C03 04  X  SPA  @0 Regeneración @5 09
C03 05  X  FRE  @0 Phosphate de calcium @5 13
C03 05  X  ENG  @0 Calcium phosphate @5 13
C03 05  X  SPA  @0 Calcio fosfato @5 13
C03 06  X  FRE  @0 Déhiscence @5 14
C03 06  X  ENG  @0 Dehiscence @5 14
C03 06  X  SPA  @0 Dehiscencia @5 14
C03 07  X  FRE  @0 Animal @5 15
C03 07  X  ENG  @0 Animal @5 15
C03 07  X  SPA  @0 Animal @5 15
C03 08  X  FRE  @0 Chien @5 16
C03 08  X  ENG  @0 Dog @5 16
C03 08  X  SPA  @0 Perro @5 16
C03 09  X  FRE  @0 Stomatologie @5 17
C03 09  X  ENG  @0 Stomatology @5 17
C03 09  X  SPA  @0 Estomatología @5 17
C03 10  X  FRE  @0 Traitement @5 30
C03 10  X  ENG  @0 Treatment @5 30
C03 10  X  SPA  @0 Tratamiento @5 30
C07 01  X  FRE  @0 Fissipedia @2 NS
C07 01  X  ENG  @0 Fissipedia @2 NS
C07 01  X  SPA  @0 Fissipedia @2 NS
C07 02  X  FRE  @0 Carnivora @2 NS
C07 02  X  ENG  @0 Carnivora @2 NS
C07 02  X  SPA  @0 Carnivora @2 NS
C07 03  X  FRE  @0 Mammalia @2 NS
C07 03  X  ENG  @0 Mammalia @2 NS
C07 03  X  SPA  @0 Mammalia @2 NS
C07 04  X  FRE  @0 Vertebrata @2 NS
C07 04  X  ENG  @0 Vertebrata @2 NS
C07 04  X  SPA  @0 Vertebrata @2 NS
N21       @1 275
N44 01      @1 OTO
N82       @1 OTO

Format Inist (serveur)

NO : PASCAL 12-0354869 INIST
ET : Guided Bone Regeneration Using Cyanoacrylate-Combined Calcium Phosphate in a Dehiscence Defect: A Histologic Study in Dogs
AU : LEE (Jung-Seok); KO (Seung-Hee); KIM (Young-Taek); JUNG (Ui-Won); CHOI (Seong-Ho)
AF : Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University/Seoul/Corée, République de (1 aut., 2 aut., 3 aut., 4 aut., 5 aut.)
DT : Publication en série; Niveau analytique
SO : Journal of oral and maxillofacial surgery; ISSN 0278-2391; Coden JOMSDA; Etats-Unis; Da. 2012; Vol. 70; No. 9; Pp. 2070-2079; Bibl. 39 ref.
LA : Anglais
EA : Purpose: This study evaluated the effects of cyanoacrylate-combined calcium phosphate (CCP) as a candidate for a barrier membrane substitute in guided bone regeneration and the space maintenance capability of CCP placed in a dehiscence defect model. Materials and Methods: Six standardized dehiscence defects (5 × 3 mm, height × width) around dental implants were created on unilateral edentulous ridges in 5 dogs, where each defect was treated with sham surgery, biphasic calcium phosphate (BCP), CCP, barrier membrane (MEM), BCP + MEM, and CCP + MEM. The animals were sacrificed after an 8-week healing interval for histologic and histometric analyses. Results: The BCP and CCP sites showed increased bone formation compared with the control sites, although incomplete defect resolution occurred; bone regeneration heights (area) averaged 3.52 ± 0.69 mm (4.94 ± 2.59 mm2), 3.51 ± 0.16 mm (4.10 ± 1.99 mm2), and 1.53 ± 0.42 mm (1.01 ± 0.74 mm2) for the BCP, CCP, and control sites, respectively. All the MEM sites showed more bone formation compared with the sites that received the same biomaterials without a MEM, and the BCP + MEM and CCP + MEM sites showed extensive bone formation within the defect and on top of the implant; the bone regeneration heights (area) averaged 3.96 ± 2.86 mm (12.46 ± 11.61 mm2), 5.45 ± 0.25 mm (11.63 ± 1.97 mm2), and 2.62 ± 0.27 mm (3.43 ± 0.98 mm2) for the BCP + MEM, CCP + MEM, and MEM sites, respectively. Conclusions: CCP can be a good scaffold for supporting an MEM as opposed to acting as a substitute for the MEM in guided bone regeneration.
CC : 002B10
FD : Chirurgie; Guidage; Os; Régénération; Phosphate de calcium; Déhiscence; Animal; Chien; Stomatologie; Traitement
FG : Fissipedia; Carnivora; Mammalia; Vertebrata
ED : Surgery; Guidance; Bone; Regeneration; Calcium phosphate; Dehiscence; Animal; Dog; Stomatology; Treatment
EG : Fissipedia; Carnivora; Mammalia; Vertebrata
SD : Cirugía; Guiado; Hueso; Regeneración; Calcio fosfato; Dehiscencia; Animal; Perro; Estomatología; Tratamiento
LO : INIST-3005.354000504462940100
ID : 12-0354869

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Pascal:12-0354869

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<div type="abstract" xml:lang="en">Purpose: This study evaluated the effects of cyanoacrylate-combined calcium phosphate (CCP) as a candidate for a barrier membrane substitute in guided bone regeneration and the space maintenance capability of CCP placed in a dehiscence defect model. Materials and Methods: Six standardized dehiscence defects (5 × 3 mm, height × width) around dental implants were created on unilateral edentulous ridges in 5 dogs, where each defect was treated with sham surgery, biphasic calcium phosphate (BCP), CCP, barrier membrane (MEM), BCP + MEM, and CCP + MEM. The animals were sacrificed after an 8-week healing interval for histologic and histometric analyses. Results: The BCP and CCP sites showed increased bone formation compared with the control sites, although incomplete defect resolution occurred; bone regeneration heights (area) averaged 3.52 ± 0.69 mm (4.94 ± 2.59 mm
<sup>2</sup>
), 3.51 ± 0.16 mm (4.10 ± 1.99 mm
<sup>2</sup>
), and 1.53 ± 0.42 mm (1.01 ± 0.74 mm
<sup>2</sup>
) for the BCP, CCP, and control sites, respectively. All the MEM sites showed more bone formation compared with the sites that received the same biomaterials without a MEM, and the BCP + MEM and CCP + MEM sites showed extensive bone formation within the defect and on top of the implant; the bone regeneration heights (area) averaged 3.96 ± 2.86 mm (12.46 ± 11.61 mm
<sup>2</sup>
), 5.45 ± 0.25 mm (11.63 ± 1.97 mm
<sup>2</sup>
), and 2.62 ± 0.27 mm (3.43 ± 0.98 mm
<sup>2</sup>
) for the BCP + MEM, CCP + MEM, and MEM sites, respectively. Conclusions: CCP can be a good scaffold for supporting an MEM as opposed to acting as a substitute for the MEM in guided bone regeneration.</div>
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<s0>Purpose: This study evaluated the effects of cyanoacrylate-combined calcium phosphate (CCP) as a candidate for a barrier membrane substitute in guided bone regeneration and the space maintenance capability of CCP placed in a dehiscence defect model. Materials and Methods: Six standardized dehiscence defects (5 × 3 mm, height × width) around dental implants were created on unilateral edentulous ridges in 5 dogs, where each defect was treated with sham surgery, biphasic calcium phosphate (BCP), CCP, barrier membrane (MEM), BCP + MEM, and CCP + MEM. The animals were sacrificed after an 8-week healing interval for histologic and histometric analyses. Results: The BCP and CCP sites showed increased bone formation compared with the control sites, although incomplete defect resolution occurred; bone regeneration heights (area) averaged 3.52 ± 0.69 mm (4.94 ± 2.59 mm
<sup>2</sup>
), 3.51 ± 0.16 mm (4.10 ± 1.99 mm
<sup>2</sup>
), and 1.53 ± 0.42 mm (1.01 ± 0.74 mm
<sup>2</sup>
) for the BCP, CCP, and control sites, respectively. All the MEM sites showed more bone formation compared with the sites that received the same biomaterials without a MEM, and the BCP + MEM and CCP + MEM sites showed extensive bone formation within the defect and on top of the implant; the bone regeneration heights (area) averaged 3.96 ± 2.86 mm (12.46 ± 11.61 mm
<sup>2</sup>
), 5.45 ± 0.25 mm (11.63 ± 1.97 mm
<sup>2</sup>
), and 2.62 ± 0.27 mm (3.43 ± 0.98 mm
<sup>2</sup>
) for the BCP + MEM, CCP + MEM, and MEM sites, respectively. Conclusions: CCP can be a good scaffold for supporting an MEM as opposed to acting as a substitute for the MEM in guided bone regeneration.</s0>
</fC01>
<fC02 i1="01" i2="X">
<s0>002B10</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE">
<s0>Chirurgie</s0>
<s5>04</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG">
<s0>Surgery</s0>
<s5>04</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA">
<s0>Cirugía</s0>
<s5>04</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE">
<s0>Guidage</s0>
<s5>07</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG">
<s0>Guidance</s0>
<s5>07</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA">
<s0>Guiado</s0>
<s5>07</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE">
<s0>Os</s0>
<s5>08</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG">
<s0>Bone</s0>
<s5>08</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA">
<s0>Hueso</s0>
<s5>08</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE">
<s0>Régénération</s0>
<s5>09</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG">
<s0>Regeneration</s0>
<s5>09</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA">
<s0>Regeneración</s0>
<s5>09</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE">
<s0>Phosphate de calcium</s0>
<s5>13</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG">
<s0>Calcium phosphate</s0>
<s5>13</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA">
<s0>Calcio fosfato</s0>
<s5>13</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE">
<s0>Déhiscence</s0>
<s5>14</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG">
<s0>Dehiscence</s0>
<s5>14</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA">
<s0>Dehiscencia</s0>
<s5>14</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE">
<s0>Animal</s0>
<s5>15</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG">
<s0>Animal</s0>
<s5>15</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA">
<s0>Animal</s0>
<s5>15</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE">
<s0>Chien</s0>
<s5>16</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG">
<s0>Dog</s0>
<s5>16</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA">
<s0>Perro</s0>
<s5>16</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE">
<s0>Stomatologie</s0>
<s5>17</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG">
<s0>Stomatology</s0>
<s5>17</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA">
<s0>Estomatología</s0>
<s5>17</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE">
<s0>Traitement</s0>
<s5>30</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG">
<s0>Treatment</s0>
<s5>30</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA">
<s0>Tratamiento</s0>
<s5>30</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Fissipedia</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Fissipedia</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Fissipedia</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Carnivora</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Carnivora</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Carnivora</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Mammalia</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Mammalia</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Mammalia</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Vertebrata</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Vertebrata</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Vertebrata</s0>
<s2>NS</s2>
</fC07>
<fN21>
<s1>275</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
<server>
<NO>PASCAL 12-0354869 INIST</NO>
<ET>Guided Bone Regeneration Using Cyanoacrylate-Combined Calcium Phosphate in a Dehiscence Defect: A Histologic Study in Dogs</ET>
<AU>LEE (Jung-Seok); KO (Seung-Hee); KIM (Young-Taek); JUNG (Ui-Won); CHOI (Seong-Ho)</AU>
<AF>Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University/Seoul/Corée, République de (1 aut., 2 aut., 3 aut., 4 aut., 5 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Journal of oral and maxillofacial surgery; ISSN 0278-2391; Coden JOMSDA; Etats-Unis; Da. 2012; Vol. 70; No. 9; Pp. 2070-2079; Bibl. 39 ref.</SO>
<LA>Anglais</LA>
<EA>Purpose: This study evaluated the effects of cyanoacrylate-combined calcium phosphate (CCP) as a candidate for a barrier membrane substitute in guided bone regeneration and the space maintenance capability of CCP placed in a dehiscence defect model. Materials and Methods: Six standardized dehiscence defects (5 × 3 mm, height × width) around dental implants were created on unilateral edentulous ridges in 5 dogs, where each defect was treated with sham surgery, biphasic calcium phosphate (BCP), CCP, barrier membrane (MEM), BCP + MEM, and CCP + MEM. The animals were sacrificed after an 8-week healing interval for histologic and histometric analyses. Results: The BCP and CCP sites showed increased bone formation compared with the control sites, although incomplete defect resolution occurred; bone regeneration heights (area) averaged 3.52 ± 0.69 mm (4.94 ± 2.59 mm
<sup>2</sup>
), 3.51 ± 0.16 mm (4.10 ± 1.99 mm
<sup>2</sup>
), and 1.53 ± 0.42 mm (1.01 ± 0.74 mm
<sup>2</sup>
) for the BCP, CCP, and control sites, respectively. All the MEM sites showed more bone formation compared with the sites that received the same biomaterials without a MEM, and the BCP + MEM and CCP + MEM sites showed extensive bone formation within the defect and on top of the implant; the bone regeneration heights (area) averaged 3.96 ± 2.86 mm (12.46 ± 11.61 mm
<sup>2</sup>
), 5.45 ± 0.25 mm (11.63 ± 1.97 mm
<sup>2</sup>
), and 2.62 ± 0.27 mm (3.43 ± 0.98 mm
<sup>2</sup>
) for the BCP + MEM, CCP + MEM, and MEM sites, respectively. Conclusions: CCP can be a good scaffold for supporting an MEM as opposed to acting as a substitute for the MEM in guided bone regeneration.</EA>
<CC>002B10</CC>
<FD>Chirurgie; Guidage; Os; Régénération; Phosphate de calcium; Déhiscence; Animal; Chien; Stomatologie; Traitement</FD>
<FG>Fissipedia; Carnivora; Mammalia; Vertebrata</FG>
<ED>Surgery; Guidance; Bone; Regeneration; Calcium phosphate; Dehiscence; Animal; Dog; Stomatology; Treatment</ED>
<EG>Fissipedia; Carnivora; Mammalia; Vertebrata</EG>
<SD>Cirugía; Guiado; Hueso; Regeneración; Calcio fosfato; Dehiscencia; Animal; Perro; Estomatología; Tratamiento</SD>
<LO>INIST-3005.354000504462940100</LO>
<ID>12-0354869</ID>
</server>
</inist>
</record>

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