Recombinant human bone morphogenetic protein 2 in augmentation procedures: case reports.
Identifieur interne : 001213 ( Ncbi/Curation ); précédent : 001212; suivant : 001214Recombinant human bone morphogenetic protein 2 in augmentation procedures: case reports.
Auteurs : Jaques Luiz ; Luis Eduardo Marques Padovan ; Marcela ClaudinoSource :
- The International journal of oral & maxillofacial implants [ 1942-4434 ]
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Collagène, Facteur de croissance transformant bêta (usage thérapeutique), Femelle, Filet chirurgical, Humains, Implants dentaires, Maxillaire (), Membrane artificielle, Minéraux (usage thérapeutique), Mâle, Pose d'implant dentaire endo-osseux (), Prothèse dentaire complète supérieure, Prothèse dentaire implanto-portée, Protéine morphogénétique osseuse de type 2 (usage thérapeutique), Protéines recombinantes (usage thérapeutique), Rehaussement du plancher du sinus (), Régénération osseuse (), Sinus maxillaire (), Substituts osseux (usage thérapeutique), Sujet âgé, Titane (), Éponge de gélatine résorbable (usage thérapeutique), Études de suivi.
- MESH :
- usage thérapeutique : Facteur de croissance transformant bêta, Minéraux, Protéine morphogénétique osseuse de type 2, Protéines recombinantes, Substituts osseux, Éponge de gélatine résorbable.
- Adulte, Adulte d'âge moyen, Collagène, Femelle, Filet chirurgical, Humains, Implants dentaires, Maxillaire, Membrane artificielle, Mâle, Pose d'implant dentaire endo-osseux, Prothèse dentaire complète supérieure, Prothèse dentaire implanto-portée, Rehaussement du plancher du sinus, Régénération osseuse, Sinus maxillaire, Sujet âgé, Titane, Études de suivi.
English descriptors
- KwdEn :
- Adult, Aged, Bone Morphogenetic Protein 2 (therapeutic use), Bone Regeneration (drug effects), Bone Substitutes (therapeutic use), Collagen, Dental Implantation, Endosseous (methods), Dental Implants, Dental Prosthesis, Implant-Supported, Denture, Complete, Upper, Female, Follow-Up Studies, Gelatin Sponge, Absorbable (therapeutic use), Humans, Male, Maxilla (surgery), Maxillary Sinus (surgery), Membranes, Artificial, Middle Aged, Minerals (therapeutic use), Recombinant Proteins (therapeutic use), Sinus Floor Augmentation (methods), Surgical Mesh, Titanium (chemistry), Transforming Growth Factor beta (therapeutic use).
- MESH :
- chemical , chemistry : Titanium.
- chemical , therapeutic use : Bone Morphogenetic Protein 2, Bone Substitutes, Minerals, Recombinant Proteins, Transforming Growth Factor beta.
- drug effects : Bone Regeneration.
- methods : Dental Implantation, Endosseous, Sinus Floor Augmentation.
- surgery : Maxilla, Maxillary Sinus.
- therapeutic use : Gelatin Sponge, Absorbable.
- Adult, Aged, Collagen, Dental Implants, Dental Prosthesis, Implant-Supported, Denture, Complete, Upper, Female, Follow-Up Studies, Humans, Male, Membranes, Artificial, Middle Aged, Surgical Mesh.
Abstract
To successfully rehabilitate edentulous patients using endosseous implants, there must be enough available bone. Several techniques have been proposed for augmentation of sites with insufficient bone volume. Although autogenous bone has long been considered the gold standard for such procedures, the limited availability of graft material and a high morbidity rate are potential disadvantages of this type of graft. An alternative is to use recombinant human bone morphogenetic protein 2 (rhBMP-2), which is able to support bone regeneration in the oral environment. These cases demonstrate the applicability of rhBMP-2 in maxillary sinus elevation and augmentation procedures in the maxilla to enable dental implant placement. The use of rhBMP-2 in alveolar augmentation procedures had several clinical benefits for these patients.
PubMed: 25216148
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pubmed:25216148Le document en format XML
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<term>Aged</term>
<term>Bone Morphogenetic Protein 2 (therapeutic use)</term>
<term>Bone Regeneration (drug effects)</term>
<term>Bone Substitutes (therapeutic use)</term>
<term>Collagen</term>
<term>Dental Implantation, Endosseous (methods)</term>
<term>Dental Implants</term>
<term>Dental Prosthesis, Implant-Supported</term>
<term>Denture, Complete, Upper</term>
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<term>Gelatin Sponge, Absorbable (therapeutic use)</term>
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<term>Adulte d'âge moyen</term>
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<term>Facteur de croissance transformant bêta (usage thérapeutique)</term>
<term>Femelle</term>
<term>Filet chirurgical</term>
<term>Humains</term>
<term>Implants dentaires</term>
<term>Maxillaire ()</term>
<term>Membrane artificielle</term>
<term>Minéraux (usage thérapeutique)</term>
<term>Mâle</term>
<term>Pose d'implant dentaire endo-osseux ()</term>
<term>Prothèse dentaire complète supérieure</term>
<term>Prothèse dentaire implanto-portée</term>
<term>Protéine morphogénétique osseuse de type 2 (usage thérapeutique)</term>
<term>Protéines recombinantes (usage thérapeutique)</term>
<term>Rehaussement du plancher du sinus ()</term>
<term>Régénération osseuse ()</term>
<term>Sinus maxillaire ()</term>
<term>Substituts osseux (usage thérapeutique)</term>
<term>Sujet âgé</term>
<term>Titane ()</term>
<term>Éponge de gélatine résorbable (usage thérapeutique)</term>
<term>Études de suivi</term>
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<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Bone Morphogenetic Protein 2</term>
<term>Bone Substitutes</term>
<term>Minerals</term>
<term>Recombinant Proteins</term>
<term>Transforming Growth Factor beta</term>
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<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Bone Regeneration</term>
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<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Dental Implantation, Endosseous</term>
<term>Sinus Floor Augmentation</term>
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<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Maxilla</term>
<term>Maxillary Sinus</term>
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</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Facteur de croissance transformant bêta</term>
<term>Minéraux</term>
<term>Protéine morphogénétique osseuse de type 2</term>
<term>Protéines recombinantes</term>
<term>Substituts osseux</term>
<term>Éponge de gélatine résorbable</term>
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<term>Aged</term>
<term>Collagen</term>
<term>Dental Implants</term>
<term>Dental Prosthesis, Implant-Supported</term>
<term>Denture, Complete, Upper</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Male</term>
<term>Membranes, Artificial</term>
<term>Middle Aged</term>
<term>Surgical Mesh</term>
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<term>Adulte d'âge moyen</term>
<term>Collagène</term>
<term>Femelle</term>
<term>Filet chirurgical</term>
<term>Humains</term>
<term>Implants dentaires</term>
<term>Maxillaire</term>
<term>Membrane artificielle</term>
<term>Mâle</term>
<term>Pose d'implant dentaire endo-osseux</term>
<term>Prothèse dentaire complète supérieure</term>
<term>Prothèse dentaire implanto-portée</term>
<term>Rehaussement du plancher du sinus</term>
<term>Régénération osseuse</term>
<term>Sinus maxillaire</term>
<term>Sujet âgé</term>
<term>Titane</term>
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<front><div type="abstract" xml:lang="en">To successfully rehabilitate edentulous patients using endosseous implants, there must be enough available bone. Several techniques have been proposed for augmentation of sites with insufficient bone volume. Although autogenous bone has long been considered the gold standard for such procedures, the limited availability of graft material and a high morbidity rate are potential disadvantages of this type of graft. An alternative is to use recombinant human bone morphogenetic protein 2 (rhBMP-2), which is able to support bone regeneration in the oral environment. These cases demonstrate the applicability of rhBMP-2 in maxillary sinus elevation and augmentation procedures in the maxilla to enable dental implant placement. The use of rhBMP-2 in alveolar augmentation procedures had several clinical benefits for these patients.</div>
</front>
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