Recombinant human bone morphogenetic protein 2 in augmentation procedures: case reports.
Identifieur interne : 000796 ( PubMed/Corpus ); précédent : 000795; suivant : 000797Recombinant human bone morphogenetic protein 2 in augmentation procedures: case reports.
Auteurs : Jaques Luiz ; Luis Eduardo Marques Padovan ; Marcela ClaudinoSource :
- The International journal of oral & maxillofacial implants [ 1942-4434 ]
English descriptors
- KwdEn :
- Adult, Aged, Bone Morphogenetic Protein 2 (therapeutic use), Bone Regeneration (drug effects), Bone Substitutes (therapeutic use), Collagen, Dental Implantation, Endosseous (methods), Dental Implants, Dental Prosthesis, Implant-Supported, Denture, Complete, Upper, Female, Follow-Up Studies, Gelatin Sponge, Absorbable (therapeutic use), Humans, Male, Maxilla (surgery), Maxillary Sinus (surgery), Membranes, Artificial, Middle Aged, Minerals (therapeutic use), Recombinant Proteins (therapeutic use), Sinus Floor Augmentation (methods), Surgical Mesh, Titanium (chemistry), Transforming Growth Factor beta (therapeutic use).
- MESH :
- chemical , chemistry : Titanium.
- chemical , therapeutic use : Bone Morphogenetic Protein 2, Bone Substitutes, Minerals, Recombinant Proteins, Transforming Growth Factor beta.
- drug effects : Bone Regeneration.
- methods : Dental Implantation, Endosseous, Sinus Floor Augmentation.
- surgery : Maxilla, Maxillary Sinus.
- therapeutic use : Gelatin Sponge, Absorbable.
- Adult, Aged, Collagen, Dental Implants, Dental Prosthesis, Implant-Supported, Denture, Complete, Upper, Female, Follow-Up Studies, Humans, Male, Membranes, Artificial, Middle Aged, Surgical Mesh.
Abstract
To successfully rehabilitate edentulous patients using endosseous implants, there must be enough available bone. Several techniques have been proposed for augmentation of sites with insufficient bone volume. Although autogenous bone has long been considered the gold standard for such procedures, the limited availability of graft material and a high morbidity rate are potential disadvantages of this type of graft. An alternative is to use recombinant human bone morphogenetic protein 2 (rhBMP-2), which is able to support bone regeneration in the oral environment. These cases demonstrate the applicability of rhBMP-2 in maxillary sinus elevation and augmentation procedures in the maxilla to enable dental implant placement. The use of rhBMP-2 in alveolar augmentation procedures had several clinical benefits for these patients.
PubMed: 25216148
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Several techniques have been proposed for augmentation of sites with insufficient bone volume. Although autogenous bone has long been considered the gold standard for such procedures, the limited availability of graft material and a high morbidity rate are potential disadvantages of this type of graft. An alternative is to use recombinant human bone morphogenetic protein 2 (rhBMP-2), which is able to support bone regeneration in the oral environment. These cases demonstrate the applicability of rhBMP-2 in maxillary sinus elevation and augmentation procedures in the maxilla to enable dental implant placement. The use of rhBMP-2 in alveolar augmentation procedures had several clinical benefits for these patients.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">25216148</PMID><DateCompleted><Year>2015</Year><Month>05</Month><Day>18</Day></DateCompleted><DateRevised><Year>2014</Year><Month>09</Month><Day>13</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1942-4434</ISSN><JournalIssue CitedMedium="Internet"><Volume>29</Volume><Issue>5</Issue><PubDate><MedlineDate>2014 Sep-Oct</MedlineDate></PubDate></JournalIssue><Title>The International journal of oral & maxillofacial implants</Title><ISOAbbreviation>Int J Oral Maxillofac Implants</ISOAbbreviation></Journal><ArticleTitle>Recombinant human bone morphogenetic protein 2 in augmentation procedures: case reports.</ArticleTitle><Pagination><MedlinePgn>1198-203</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.11607/jomi.3543</ELocationID><Abstract><AbstractText>To successfully rehabilitate edentulous patients using endosseous implants, there must be enough available bone. Several techniques have been proposed for augmentation of sites with insufficient bone volume. Although autogenous bone has long been considered the gold standard for such procedures, the limited availability of graft material and a high morbidity rate are potential disadvantages of this type of graft. An alternative is to use recombinant human bone morphogenetic protein 2 (rhBMP-2), which is able to support bone regeneration in the oral environment. These cases demonstrate the applicability of rhBMP-2 in maxillary sinus elevation and augmentation procedures in the maxilla to enable dental implant placement. 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