Clinical Similarities and Histological Diversity Comparing Fresh Frozen Onlay Bone Blocks Allografts and Autografts in Human Maxillary Reconstruction
Identifieur interne : 000239 ( Istex/Corpus ); précédent : 000238; suivant : 000240Clinical Similarities and Histological Diversity Comparing Fresh Frozen Onlay Bone Blocks Allografts and Autografts in Human Maxillary Reconstruction
Auteurs : Rubens Spin-Neto ; Ricardo Andrés Landazuri Del Barrio ; Luis Antonio Violin Dias Pereira ; Rosemary Adriana Chiérici Marcantonio ; Elcio Marcantonio ; Elcio Marcantonio JrSource :
- Clinical Implant Dentistry and Related Research [ 1523-0899 ] ; 2013-08.
English descriptors
- KwdEn :
- Allograft, Allograft bone, Alveolar ridge width, American association, Araraquara, Associate professor, Banking, Biopsy, Biopsy area, Bone, Bone allograft, Bone allografts, Bone allografts group, Bone graft, Bone grafts, Bone regeneration, Bone transplantation, Bone volume, Cell tissue bank, Clin, Clin orthop relat, Clinical implant dentistry, Dent, Dental implants, Disease transmission, Donor sites, Elcio marcantonio, Empty osteocytes lacunae, Energy agency, Estadual paulista, Exuberant osteocytes, Freshfrozen bone allografts, Full biopsy view, Graft, Graft blocks, Grafted, Grafted bone, Grafted material, Haversian canals, Histological, Histological analysis, Host bone, Host bone site, Host site, Human maxilla, Human maxillary reconstruction, Iaea, Iliac bone, Implant, Implant dent, Implant placement, Implants placement, Leica microsystems, Macroscopic analysis, Mandibular, Mandibular reconstruction, Maxilla, Maxillary, Maxillary reconstruction, Maxillary ridge augmentation, Maxillofac, Microscopic analysis, Morales pedraza, Morphometric evaluation, Native bone, Native bone areas, Necrotic, Necrotic bone, Oral maxillofac implants, Oral maxillofac surg, Orthop, Osseointegrated implant, Osteoinductive properties, Paulo, Pedraza, Preliminary report, Primary bone, Process chronology, Prosthet dent, Residual bone, Resorbed maxillae, Retrospective study, Small frame, Stereomicroscopy analysis, Surg, Surgical procedure, Threedimensional bone interface, Tissue banking, Tissue banks, Titanium implants, Unesp univ, Unremodeled bone.
- Teeft :
- Allograft, Allograft bone, Alveolar ridge width, American association, Araraquara, Associate professor, Banking, Biopsy, Biopsy area, Bone, Bone allograft, Bone allografts, Bone allografts group, Bone graft, Bone grafts, Bone regeneration, Bone transplantation, Bone volume, Cell tissue bank, Clin, Clin orthop relat, Clinical implant dentistry, Dent, Dental implants, Disease transmission, Donor sites, Elcio marcantonio, Empty osteocytes lacunae, Energy agency, Estadual paulista, Exuberant osteocytes, Freshfrozen bone allografts, Full biopsy view, Graft, Graft blocks, Grafted, Grafted bone, Grafted material, Haversian canals, Histological, Histological analysis, Host bone, Host bone site, Host site, Human maxilla, Human maxillary reconstruction, Iaea, Iliac bone, Implant, Implant dent, Implant placement, Implants placement, Leica microsystems, Macroscopic analysis, Mandibular, Mandibular reconstruction, Maxilla, Maxillary, Maxillary reconstruction, Maxillary ridge augmentation, Maxillofac, Microscopic analysis, Morales pedraza, Morphometric evaluation, Native bone, Native bone areas, Necrotic, Necrotic bone, Oral maxillofac implants, Oral maxillofac surg, Orthop, Osseointegrated implant, Osteoinductive properties, Paulo, Pedraza, Preliminary report, Primary bone, Process chronology, Prosthet dent, Residual bone, Resorbed maxillae, Retrospective study, Small frame, Stereomicroscopy analysis, Surg, Surgical procedure, Threedimensional bone interface, Tissue banking, Tissue banks, Titanium implants, Unesp univ, Unremodeled bone.
Abstract
Background: In the absence of autologous bone for harvesting, fresh‐frozen bone allografts turned into an alternative for bone reconstruction procedures.
Url:
DOI: 10.1111/j.1708-8208.2011.00382.x
Links to Exploration step
ISTEX:412D1A8B0FECED5F40C49C072A9379657D4E2A93Le document en format XML
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Estadual Paulista, Araraquara Dental School, Department of Periodontology, Araraquara, São Paulo, Brazil</json:string></affiliations></json:item><json:item><name>Ricardo Andrés Landazuri Del Barrio DDS, MSc</name><affiliations><json:string>PhD student, UNESP – Univ. Estadual Paulista, Araraquara Dental School, Department of Periodontology, Araraquara, São Paulo, Brazil</json:string></affiliations></json:item><json:item><name>Luis Antonio Violin Dias Pereira MD, PhD</name><affiliations><json:string>associate professor, UNICAMP – State University of Campinas, Institute of Biology, Department of Histology and Embryology, Campinas, São Paulo, Brazil</json:string></affiliations></json:item><json:item><name>Rosemary Adriana Chiérici Marcantonio MSc, PhD</name><affiliations><json:string>associate professor, UNESP – Univ. Estadual Paulista, Araraquara Dental School, Department of Periodontology, Araraquara, São Paulo, Brazil</json:string></affiliations></json:item><json:item><name>Elcio Marcantonio MSc, PhD</name><affiliations><json:string>professor, UNESP – Univ. Estadual Paulista, Araraquara Dental School, Department of Bucco‐Maxillo‐Facial Surgery, Araraquara, São Paulo, Brazil</json:string></affiliations></json:item><json:item><name>Elcio Marcantonio Jr MSc, PhD</name><affiliations><json:string>professor, UNESP – Univ. 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science</json:string><json:string>2 - dentistry, oral surgery & medicine</json:string></wos><scienceMetrix><json:string>1 - health sciences</json:string><json:string>2 - clinical medicine</json:string><json:string>3 - dentistry</json:string></scienceMetrix><scopus><json:string>1 - Health Sciences</json:string><json:string>2 - Dentistry</json:string><json:string>3 - General Dentistry</json:string><json:string>1 - Health Sciences</json:string><json:string>2 - Dentistry</json:string><json:string>3 - Oral Surgery</json:string></scopus></categories><publicationDate>2013</publicationDate><copyrightDate>2013</copyrightDate><doi><json:string>10.1111/j.1708-8208.2011.00382.x</json:string></doi><id>412D1A8B0FECED5F40C49C072A9379657D4E2A93</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/412D1A8B0FECED5F40C49C072A9379657D4E2A93/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/412D1A8B0FECED5F40C49C072A9379657D4E2A93/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/412D1A8B0FECED5F40C49C072A9379657D4E2A93/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main">Clinical Similarities and Histological Diversity Comparing Fresh Frozen Onlay Bone Blocks Allografts and Autografts in Human Maxillary Reconstruction</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><availability><licence>© 2011 Wiley Periodicals, Inc.</licence></availability><date type="published" when="2013-08"></date></publicationStmt><notesStmt><note type="content-type" subtype="article" source="article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="article"><analytic><title level="a" type="main">Clinical Similarities and Histological Diversity Comparing Fresh Frozen Onlay Bone Blocks Allografts and Autografts in Human Maxillary Reconstruction</title><title level="a" type="short">Allografts in Human Maxillary Reconstruction</title><author xml:id="author-0000"><persName><forename type="first">Rubens</forename><surname>Spin‐Neto</surname><roleName type="degree">DDS, MSc</roleName></persName><affiliation>PhD student, UNESP – Univ. Estadual Paulista, Araraquara Dental School, Department of Periodontology, Araraquara, São Paulo, Brazil<address><country key="BR"></country></address></affiliation></author><author xml:id="author-0001"><persName><forename type="first">Ricardo Andrés</forename><surname>Landazuri Del Barrio</surname><roleName type="degree">DDS, MSc</roleName></persName><affiliation>PhD student, UNESP – Univ. Estadual Paulista, Araraquara Dental School, Department of Periodontology, Araraquara, São Paulo, Brazil<address><country key="BR"></country></address></affiliation></author><author xml:id="author-0002"><persName><forename type="first">Luis Antonio Violin Dias</forename><surname>Pereira</surname><roleName type="degree">MD, PhD</roleName></persName><affiliation>associate professor, UNICAMP – State University of Campinas, Institute of Biology, Department of Histology and Embryology, Campinas, São Paulo, Brazil<address><country key="BR"></country></address></affiliation></author><author xml:id="author-0003"><persName><forename type="first">Rosemary Adriana Chiérici</forename><surname>Marcantonio</surname><roleName type="degree">MSc, PhD</roleName></persName><affiliation>associate professor, UNESP – Univ. Estadual Paulista, Araraquara Dental School, Department of Periodontology, Araraquara, São Paulo, Brazil<address><country key="BR"></country></address></affiliation></author><author xml:id="author-0004"><persName><forename type="first">Elcio</forename><surname>Marcantonio</surname><roleName type="degree">MSc, PhD</roleName></persName><affiliation>professor, UNESP – Univ. Estadual Paulista, Araraquara Dental School, Department of Bucco‐Maxillo‐Facial Surgery, Araraquara, São Paulo, Brazil<address><country key="BR"></country></address></affiliation></author><author xml:id="author-0005" role="corresp"><persName><forename type="first">Elcio</forename><surname>Marcantonio Jr</surname><roleName type="degree">MSc, PhD</roleName></persName><affiliation>professor, UNESP – Univ. Estadual Paulista, Araraquara Dental School, Department of Periodontology, Araraquara, São Paulo, Brazil<address><country key="BR"></country></address></affiliation><affiliation>Professor Elcio Marcantonio Junior, Department of Periodontology, UNESP – Univ. Estadual Paulista, Rua Humaitá, 1680 – CEP, 14801‐903‐Araraquara‐SP, Brazil; e‐mail: elciojr@foar.unesp.br</affiliation></author><idno type="istex">412D1A8B0FECED5F40C49C072A9379657D4E2A93</idno><idno type="ark">ark:/67375/WNG-C7GW2MCS-4</idno><idno type="DOI">10.1111/j.1708-8208.2011.00382.x</idno><idno type="unit">CID382</idno><idno type="toTypesetVersion">file:CID.CID382.pdf</idno></analytic><monogr><title level="j" type="main">Clinical Implant Dentistry and Related Research</title><title level="j" type="alt">CLINICAL IMPLANT DENTISTRY RELATED RESEARCH</title><idno type="pISSN">1523-0899</idno><idno type="eISSN">1708-8208</idno><idno type="book-DOI">10.1111/(ISSN)1708-8208</idno><idno type="book-part-DOI">10.1111/cid.2013.15.issue-4</idno><idno type="product">CID</idno><idno type="publisherDivision">ST</idno><imprint><biblScope unit="vol">15</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="490">490</biblScope><biblScope unit="page" to="497">497</biblScope><biblScope unit="page-count">8</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2013-08"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><abstract xml:lang="en" style="main"><head>ABSTRACT</head><p><hi rend="bold">Background:</hi> In the absence of autologous bone for harvesting, fresh‐frozen bone allografts turned into an alternative for bone reconstruction procedures.</p><p><hi rend="bold">Purpose:</hi> The purpose of this study was to make a histological analysis of fresh‐frozen onlay bone allografts (ALs), compared with autografts, in patients who needed maxillary reconstruction prior to dental implants placement.</p><p><hi rend="bold">Materials and Methods:</hi> Twelve patients with bone deficiencies (width inferior to 4 mm) in the sites where the implants were planned were enrolled in the study. From these, six were elected to be treated with autogenous (AT) bone grafts and six with fresh‐frozen bone AL. This last group included the patients who had absence of a convenient amount of bone in donor sites. Each patient received from one to six graft blocks, totalling to 12 ATs and 17 ALs. Seven months after grafting procedures, biopsies of the grafts were made using 2‐mm internal diameter trephine burs, and processed for histological analysis. One biopsy was retrieved from each patient.</p><p><hi rend="bold">Results:</hi> Clinically, all grafts were found to be firm in consistency and well‐incorporated to the receptor bed. Histological analysis showed a large amount of necrotic bone surrounded by few spots of new‐formed bone in the AL group, suggesting low rate of graft remodeling. In the AT group, an advanced stage of bone remodeling was seen.</p><p><hi rend="bold">Conclusions:</hi> Human fresh‐frozen bone block AL showed clinical compatibility for grafting procedures, although associated to slow remodeling process. Further studies are needed to define, at long term, the remodeling process chronology the clinical longitudinal results for fresh‐frozen bone AL.</p></abstract><textClass><keywords xml:lang="en"><term xml:id="k1">atrophic maxillae</term><term xml:id="k2">bone allograft</term><term xml:id="k3">histological analysis</term></keywords><keywords rend="tocHeading1"><term>ARTICLES</term></keywords><keywords rend="articleCategory"><term>ARTICLE</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/412D1A8B0FECED5F40C49C072A9379657D4E2A93/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Publishing Ltd</publisherName><publisherLoc>Oxford, UK</publisherLoc></publisherInfo><doi origin="wiley" registered="yes">10.1111/(ISSN)1708-8208</doi><issn type="print">1523-0899</issn><issn type="electronic">1708-8208</issn><idGroup><id type="product" value="CID"></id><id type="publisherDivision" value="ST"></id></idGroup><titleGroup><title type="main" sort="CLINICAL IMPLANT DENTISTRY RELATED RESEARCH">Clinical Implant Dentistry and Related Research</title></titleGroup></publicationMeta><publicationMeta level="part" position="08104"><doi>10.1111/cid.2013.15.issue-4</doi><copyright ownership="publisher">Copyright © 2013 Wiley Periodicals, Inc.</copyright><numberingGroup><numbering number="15" type="journalVolume">15</numbering><numbering type="journalIssue">4</numbering></numberingGroup><coverDate startDate="2013-08">August 2013</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="30" status="forIssue"><doi origin="wiley">10.1111/j.1708-8208.2011.00382.x</doi><idGroup><id type="unit" value="CID382"></id></idGroup><countGroup><count type="pageTotal" number="8"></count></countGroup><titleGroup><title type="tocHeading1">ARTICLES</title><title type="articleCategory">ARTICLE</title></titleGroup><copyright>© 2011 Wiley Periodicals, Inc.</copyright><eventGroup><event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:3.2.3 mode:FullText" date="2013-07-28"></event><event date="2013-07-29" type="xmlCorrected"></event><event type="publishedOnlineEarlyUnpaginated" date="2011-08-11"></event><event type="firstOnline" date="2011-08-11"></event><event type="publishedOnlineFinalForm" date="2013-08-01"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-15"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.6.4 mode:FullText" date="2015-10-01"></event></eventGroup><numberingGroup><numbering type="pageFirst">490</numbering><numbering type="pageLast">497</numbering></numberingGroup><correspondenceTo>Professor Elcio Marcantonio Junior, Department of Periodontology, UNESP – Univ. Estadual Paulista, Rua Humaitá, 1680 – CEP, 14801‐903‐Araraquara‐SP, Brazil; e‐mail: <email>elciojr@foar.unesp.br</email></correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:CID.CID382.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="7"></count><count type="tableTotal" number="0"></count><count type="formulaTotal" number="0"></count><count type="referenceTotal" number="58"></count><count type="wordTotal" number="4768"></count><count type="linksPubMed" number="0"></count><count type="linksCrossRef" number="0"></count></countGroup><titleGroup><title type="main">Clinical Similarities and Histological Diversity Comparing Fresh Frozen Onlay Bone Blocks Allografts and Autografts in Human Maxillary Reconstruction</title><title type="shortAuthors">Clinical Implant Dentistry and Related Research, Volume *, Number *, 2011</title><title type="short">Allografts in Human Maxillary Reconstruction</title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1"><personName><givenNames>Rubens</givenNames><familyName>Spin‐Neto</familyName><degrees>DDS, MSc</degrees></personName></creator><creator creatorRole="author" xml:id="cr2" affiliationRef="#a1"><personName><givenNames>Ricardo Andrés</givenNames><familyName>Landazuri Del Barrio</familyName><degrees>DDS, MSc</degrees></personName></creator><creator creatorRole="author" xml:id="cr3" affiliationRef="#a2"><personName><givenNames>Luis Antonio Violin Dias</givenNames><familyName>Pereira</familyName><degrees>MD, PhD</degrees></personName></creator><creator creatorRole="author" xml:id="cr4" affiliationRef="#a3"><personName><givenNames>Rosemary Adriana Chiérici</givenNames><familyName>Marcantonio</familyName><degrees>MSc, PhD</degrees></personName></creator><creator creatorRole="author" xml:id="cr5" affiliationRef="#a4"><personName><givenNames>Elcio</givenNames><familyName>Marcantonio</familyName><degrees>MSc, PhD</degrees></personName></creator><creator creatorRole="author" xml:id="cr6" affiliationRef="#a5" corresponding="yes"><personName><givenNames>Elcio</givenNames><familyName>Marcantonio Jr</familyName><degrees>MSc, PhD</degrees></personName></creator></creators><affiliationGroup><affiliation xml:id="a1" countryCode="BR"><unparsedAffiliation>PhD student, UNESP – Univ. Estadual Paulista, Araraquara Dental School, Department of Periodontology, Araraquara, São Paulo, Brazil</unparsedAffiliation></affiliation><affiliation xml:id="a2" countryCode="BR"><unparsedAffiliation>associate professor, UNICAMP – State University of Campinas, Institute of Biology, Department of Histology and Embryology, Campinas, São Paulo, Brazil</unparsedAffiliation></affiliation><affiliation xml:id="a3" countryCode="BR"><unparsedAffiliation>associate professor, UNESP – Univ. Estadual Paulista, Araraquara Dental School, Department of Periodontology, Araraquara, São Paulo, Brazil</unparsedAffiliation></affiliation><affiliation xml:id="a4" countryCode="BR"><unparsedAffiliation>professor, UNESP – Univ. Estadual Paulista, Araraquara Dental School, Department of Bucco‐Maxillo‐Facial Surgery, Araraquara, São Paulo, Brazil</unparsedAffiliation></affiliation><affiliation xml:id="a5" countryCode="BR"><unparsedAffiliation>professor, UNESP – Univ. Estadual Paulista, Araraquara Dental School, Department of Periodontology, Araraquara, São Paulo, Brazil</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en"><keyword xml:id="k1">atrophic maxillae</keyword><keyword xml:id="k2">bone allograft</keyword><keyword xml:id="k3">histological analysis</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">ABSTRACT</title><p><b>Background:</b> In the absence of autologous bone for harvesting, fresh‐frozen bone allografts turned into an alternative for bone reconstruction procedures.</p><p><b>Purpose:</b> The purpose of this study was to make a histological analysis of fresh‐frozen onlay bone allografts (ALs), compared with autografts, in patients who needed maxillary reconstruction prior to dental implants placement.</p><p><b>Materials and Methods:</b> Twelve patients with bone deficiencies (width inferior to 4 mm) in the sites where the implants were planned were enrolled in the study. From these, six were elected to be treated with autogenous (AT) bone grafts and six with fresh‐frozen bone AL. This last group included the patients who had absence of a convenient amount of bone in donor sites. Each patient received from one to six graft blocks, totalling to 12 ATs and 17 ALs. Seven months after grafting procedures, biopsies of the grafts were made using 2‐mm internal diameter trephine burs, and processed for histological analysis. One biopsy was retrieved from each patient.</p><p><b>Results:</b> Clinically, all grafts were found to be firm in consistency and well‐incorporated to the receptor bed. Histological analysis showed a large amount of necrotic bone surrounded by few spots of new‐formed bone in the AL group, suggesting low rate of graft remodeling. In the AT group, an advanced stage of bone remodeling was seen.</p><p><b>Conclusions:</b> Human fresh‐frozen bone block AL showed clinical compatibility for grafting procedures, although associated to slow remodeling process. Further studies are needed to define, at long term, the remodeling process chronology the clinical longitudinal results for fresh‐frozen bone AL.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Clinical Similarities and Histological Diversity Comparing Fresh Frozen Onlay Bone Blocks Allografts and Autografts in Human Maxillary Reconstruction</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Allografts in Human Maxillary Reconstruction</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Clinical Similarities and Histological Diversity Comparing Fresh Frozen Onlay Bone Blocks Allografts and Autografts in Human Maxillary Reconstruction</title></titleInfo><name type="personal"><namePart type="given">Rubens</namePart><namePart type="family">Spin‐Neto</namePart><namePart type="termsOfAddress">DDS, MSc</namePart><affiliation>PhD student, UNESP – Univ. Estadual Paulista, Araraquara Dental School, Department of Periodontology, Araraquara, São Paulo, Brazil</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ricardo Andrés</namePart><namePart type="family">Landazuri Del Barrio</namePart><namePart type="termsOfAddress">DDS, MSc</namePart><affiliation>PhD student, UNESP – Univ. Estadual Paulista, Araraquara Dental School, Department of Periodontology, Araraquara, São Paulo, Brazil</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Luis Antonio Violin Dias</namePart><namePart type="family">Pereira</namePart><namePart type="termsOfAddress">MD, PhD</namePart><affiliation>associate professor, UNICAMP – State University of Campinas, Institute of Biology, Department of Histology and Embryology, Campinas, São Paulo, Brazil</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Rosemary Adriana Chiérici</namePart><namePart type="family">Marcantonio</namePart><namePart type="termsOfAddress">MSc, PhD</namePart><affiliation>associate professor, UNESP – Univ. Estadual Paulista, Araraquara Dental School, Department of Periodontology, Araraquara, São Paulo, Brazil</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Elcio</namePart><namePart type="family">Marcantonio</namePart><namePart type="termsOfAddress">MSc, PhD</namePart><affiliation>professor, UNESP – Univ. Estadual Paulista, Araraquara Dental School, Department of Bucco‐Maxillo‐Facial Surgery, Araraquara, São Paulo, Brazil</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Elcio</namePart><namePart type="family">Marcantonio Jr</namePart><namePart type="termsOfAddress">MSc, PhD</namePart><affiliation>professor, UNESP – Univ. Estadual Paulista, Araraquara Dental School, Department of Periodontology, Araraquara, São Paulo, Brazil</affiliation><affiliation>E-mail: elciojr@foar.unesp.br</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">2013-08</dateIssued><copyrightDate encoding="w3cdtf">2013</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="figures">7</extent><extent unit="tables">0</extent><extent unit="formulas">0</extent><extent unit="references">58</extent><extent unit="linksCrossRef">0</extent><extent unit="words">4768</extent></physicalDescription><abstract>Background: In the absence of autologous bone for harvesting, fresh‐frozen bone allografts turned into an alternative for bone reconstruction procedures.</abstract><abstract>Purpose: The purpose of this study was to make a histological analysis of fresh‐frozen onlay bone allografts (ALs), compared with autografts, in patients who needed maxillary reconstruction prior to dental implants placement.</abstract><abstract>Materials and Methods: Twelve patients with bone deficiencies (width inferior to 4 mm) in the sites where the implants were planned were enrolled in the study. From these, six were elected to be treated with autogenous (AT) bone grafts and six with fresh‐frozen bone AL. This last group included the patients who had absence of a convenient amount of bone in donor sites. Each patient received from one to six graft blocks, totalling to 12 ATs and 17 ALs. Seven months after grafting procedures, biopsies of the grafts were made using 2‐mm internal diameter trephine burs, and processed for histological analysis. One biopsy was retrieved from each patient.</abstract><abstract>Results: Clinically, all grafts were found to be firm in consistency and well‐incorporated to the receptor bed. Histological analysis showed a large amount of necrotic bone surrounded by few spots of new‐formed bone in the AL group, suggesting low rate of graft remodeling. In the AT group, an advanced stage of bone remodeling was seen.</abstract><abstract>Conclusions: Human fresh‐frozen bone block AL showed clinical compatibility for grafting procedures, although associated to slow remodeling process. Further studies are needed to define, at long term, the remodeling process chronology the clinical longitudinal results for fresh‐frozen bone AL.</abstract><subject lang="en"><genre>keywords</genre><topic>atrophic maxillae</topic><topic>bone allograft</topic><topic>histological analysis</topic></subject><relatedItem type="host"><titleInfo><title>Clinical Implant Dentistry and Related Research</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><subject><genre>article-category</genre><topic>ARTICLE</topic></subject><identifier type="ISSN">1523-0899</identifier><identifier type="eISSN">1708-8208</identifier><identifier type="DOI">10.1111/(ISSN)1708-8208</identifier><identifier type="PublisherID">CID</identifier><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>15</number></detail><detail type="issue"><caption>no.</caption><number>4</number></detail><extent unit="pages"><start>490</start><end>497</end><total>8</total></extent></part></relatedItem><identifier type="istex">412D1A8B0FECED5F40C49C072A9379657D4E2A93</identifier><identifier type="ark">ark:/67375/WNG-C7GW2MCS-4</identifier><identifier type="DOI">10.1111/j.1708-8208.2011.00382.x</identifier><identifier type="ArticleID">CID382</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2013 Wiley Periodicals, Inc.© 2011 Wiley Periodicals, Inc.</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-L0C46X92-X">wiley</recordContentSource><recordOrigin>Blackwell Publishing Ltd</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/document/412D1A8B0FECED5F40C49C072A9379657D4E2A93/metadata/json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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