Inhibition by monensin of human cytomegalovirus DNA replication
Identifieur interne : 000184 ( Pmc/Corpus ); précédent : 000183; suivant : 000185Inhibition by monensin of human cytomegalovirus DNA replication
Auteurs : C. J. Kaiser ; K. RadsakSource :
- Archives of Virology [ 0304-8608 ] ; 1987.
Abstract
Monensin, at concentrations which depended on the multiplicity of infection, was found to prevent DNA replication of human cytomegalovirus (HCMV) as well as production of viral progeny in human foreskin fibroblasts. The drug did not affect DNA replication of herpes simplex virus. Inhibition of consecutive HCMV DNA synthesis was also observed following delayed addition of the drug within 12–24 hours postinfection, but was fully reversible upon its removal. Viral replication proceeded, however, without impairment in cultures treated with monensin prior to infection. Induction of viral DNA polymerase activity was not impeded by the inhibitor. Analysis of protein- and glycoprotein synthesis revealed that monensin interfered with the production of a number of HCMV-specific polypeptides. Furthermore, evidence was obtained that the drug may hinder intracellular transport of a 135 kd glycopolypeptide.
Url:
DOI: 10.1007/BF01310716
PubMed: 3034210
PubMed Central: 7086728
Links to Exploration step
PMC:7086728Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Inhibition by monensin of human cytomegalovirus DNA replication</title><author><name sortKey="Kaiser, C J" sort="Kaiser, C J" uniqKey="Kaiser C" first="C. J." last="Kaiser">C. J. Kaiser</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Radsak, K" sort="Radsak, K" uniqKey="Radsak K" first="K." last="Radsak">K. Radsak</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">3034210</idno><idno type="pmc">7086728</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086728</idno><idno type="RBID">PMC:7086728</idno><idno type="doi">10.1007/BF01310716</idno><date when="1987">1987</date><idno type="wicri:Area/Pmc/Corpus">000184</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000184</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Inhibition by monensin of human cytomegalovirus DNA replication</title><author><name sortKey="Kaiser, C J" sort="Kaiser, C J" uniqKey="Kaiser C" first="C. J." last="Kaiser">C. J. Kaiser</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Radsak, K" sort="Radsak, K" uniqKey="Radsak K" first="K." last="Radsak">K. Radsak</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author></analytic><series><title level="j">Archives of Virology</title><idno type="ISSN">0304-8608</idno><idno type="eISSN">1432-8798</idno><imprint><date when="1987">1987</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Summary</title><p>Monensin, at concentrations which depended on the multiplicity of infection, was found to prevent DNA replication of human cytomegalovirus (HCMV) as well as production of viral progeny in human foreskin fibroblasts. The drug did not affect DNA replication of herpes simplex virus. Inhibition of consecutive HCMV DNA synthesis was also observed following delayed addition of the drug within 12–24 hours postinfection, but was fully reversible upon its removal. Viral replication proceeded, however, without impairment in cultures treated with monensin prior to infection. Induction of viral DNA polymerase activity was not impeded by the inhibitor. Analysis of protein- and glycoprotein synthesis revealed that monensin interfered with the production of a number of HCMV-specific polypeptides. Furthermore, evidence was obtained that the drug may hinder intracellular transport of a 135 kd glycopolypeptide.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Bonner, Wm" uniqKey="Bonner W">WM Bonner</name></author><author><name sortKey="Laskey, Ra" uniqKey="Laskey R">RA Laskey</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Britt, Wj" uniqKey="Britt W">WJ Britt</name></author><author><name sortKey="Auger, D" uniqKey="Auger D">D Auger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Demarchi, J" uniqKey="Demarchi J">J Demarchi</name></author><author><name sortKey="Kaplan, As" uniqKey="Kaplan A">AS Kaplan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fioretti, A" uniqKey="Fioretti A">A Fioretti</name></author><author><name sortKey="Furukawa, T" uniqKey="Furukawa T">T Furukawa</name></author><author><name sortKey="Santoli, D" uniqKey="Santoli D">D Santoli</name></author><author><name sortKey="Plotkin, S" uniqKey="Plotkin S">S Plotkin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Furukawa, T" uniqKey="Furukawa T">T Furukawa</name></author><author><name sortKey="Fioretti, A" uniqKey="Fioretti A">A Fioretti</name></author><author><name sortKey="Plotkin, S" uniqKey="Plotkin S">S Plotkin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Furukawa, T" uniqKey="Furukawa T">T Furukawa</name></author><author><name sortKey="Gonczol, E" uniqKey="Gonczol E">E Gönczöl</name></author><author><name sortKey="Starr, S" uniqKey="Starr S">S Starr</name></author><author><name sortKey="Tolpin, Md" uniqKey="Tolpin M">MD Tolpin</name></author><author><name sortKey="Arbeter, A" uniqKey="Arbeter A">A Arbeter</name></author><author><name sortKey="Plotkin, S" uniqKey="Plotkin S">S Plotkin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Furukawa, T" uniqKey="Furukawa T">T Furukawa</name></author><author><name sortKey="Tanaka, S" uniqKey="Tanaka S">S Tanaka</name></author><author><name sortKey="Plotkin, S" uniqKey="Plotkin S">S Plotkin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gallwitz, D" uniqKey="Gallwitz D">D Gallwitz</name></author><author><name sortKey="Bos, E" uniqKey="Bos E">E Bos</name></author><author><name sortKey="Stahl, H" uniqKey="Stahl H">H Stahl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Giles, Kw" uniqKey="Giles K">KW Giles</name></author><author><name sortKey="Myers, A" uniqKey="Myers A">A Myers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hirai, K" uniqKey="Hirai K">K Hirai</name></author><author><name sortKey="Watanabe, Y" uniqKey="Watanabe Y">Y Watanabe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Iwasaki, Y" uniqKey="Iwasaki Y">Y Iwasaki</name></author><author><name sortKey="Furukawa, T" uniqKey="Furukawa T">T Furukawa</name></author><author><name sortKey="Plotkin, S" uniqKey="Plotkin S">S Plotkin</name></author><author><name sortKey="Koprowski, H" uniqKey="Koprowski H">H Koprowski</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Johnson, Dc" uniqKey="Johnson D">DC Johnson</name></author><author><name sortKey="Schlesinger, Mj" uniqKey="Schlesinger M">MJ Schlesinger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Johnson, Dc" uniqKey="Johnson D">DC Johnson</name></author><author><name sortKey="Spear, Pg" uniqKey="Spear P">PG Spear</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kerr, Cl" uniqKey="Kerr C">CL Kerr</name></author><author><name sortKey="Pennington, Th" uniqKey="Pennington T">TH Pennington</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="K Ri Inen, L" uniqKey="K Ri Inen L">L Kääriäinen</name></author><author><name sortKey="Hashimoto, K" uniqKey="Hashimoto K">K Hashimoto</name></author><author><name sortKey="Saraste, J" uniqKey="Saraste J">J Saraste</name></author><author><name sortKey="Virtanen, I" uniqKey="Virtanen I">I Virtanen</name></author><author><name sortKey="Penttinen, K" uniqKey="Penttinen K">K Penttinen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="L Mmli, Uk" uniqKey="L Mmli U">UK Lämmli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lowry, Oh" uniqKey="Lowry O">OH Lowry</name></author><author><name sortKey="Rosebrough, Nj" uniqKey="Rosebrough N">NJ Rosebrough</name></author><author><name sortKey="Farr, Al" uniqKey="Farr A">AL Farr</name></author><author><name sortKey="Randall, Rj" uniqKey="Randall R">RJ Randall</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ludwig, H" uniqKey="Ludwig H">H Ludwig</name></author><author><name sortKey="Rott, R" uniqKey="Rott R">R Rott</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Luuokonen, A" uniqKey="Luuokonen A">A Luuokonen</name></author><author><name sortKey="Gahmberg, Cg" uniqKey="Gahmberg C">CG Gahmberg</name></author><author><name sortKey="Renkonen, O" uniqKey="Renkonen O">O Renkonen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Musiani, M" uniqKey="Musiani M">M Musiani</name></author><author><name sortKey="Zerbini, M" uniqKey="Zerbini M">M Zerbini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Niemann, H" uniqKey="Niemann H">H Niemann</name></author><author><name sortKey="Boschek, B" uniqKey="Boschek B">B Boschek</name></author><author><name sortKey="Evans, E" uniqKey="Evans E">E Evans</name></author><author><name sortKey="Rosing, M" uniqKey="Rosing M">M Rosing</name></author><author><name sortKey="Tamura, T" uniqKey="Tamura T">T Tamura</name></author><author><name sortKey="Klenk, Hd" uniqKey="Klenk H">HD Klenk</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Norrild, B" uniqKey="Norrild B">B Norrild</name></author><author><name sortKey="Virtanen, I" uniqKey="Virtanen I">I Virtanen</name></author><author><name sortKey="Pedersen, B" uniqKey="Pedersen B">B Pedersen</name></author><author><name sortKey="Pereira, L" uniqKey="Pereira L">L Pereira</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nowak, B" uniqKey="Nowak B">B Nowak</name></author><author><name sortKey="Sullivan, C" uniqKey="Sullivan C">C Sullivan</name></author><author><name sortKey="Sarnow, P" uniqKey="Sarnow P">P Sarnow</name></author><author><name sortKey="Thomas, R" uniqKey="Thomas R">R Thomas</name></author><author><name sortKey="Bricout, F" uniqKey="Bricout F">F Bricout</name></author><author><name sortKey="Nicolas, Jc" uniqKey="Nicolas J">JC Nicolas</name></author><author><name sortKey="Fleckenstein, B" uniqKey="Fleckenstein B">B Fleckenstein</name></author><author><name sortKey="Levine, Aj" uniqKey="Levine A">AJ Levine</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Payne, Lg" uniqKey="Payne L">LG Payne</name></author><author><name sortKey="Kristensson, K" uniqKey="Kristensson K">K Kristensson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pereira, L" uniqKey="Pereira L">L Pereira</name></author><author><name sortKey="Hoffman, M" uniqKey="Hoffman M">M Hoffman</name></author><author><name sortKey="Tatsuno, M" uniqKey="Tatsuno M">M Tatsuno</name></author><author><name sortKey="Dondero, D" uniqKey="Dondero D">D Dondero</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Radsak, K" uniqKey="Radsak K">K Radsak</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Radsak, K" uniqKey="Radsak K">K Radsak</name></author><author><name sortKey="Furukawa, T" uniqKey="Furukawa T">T Furukawa</name></author><author><name sortKey="Plotkin, S" uniqKey="Plotkin S">S Plotkin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Radsak, K" uniqKey="Radsak K">K Radsak</name></author><author><name sortKey="Weder, D" uniqKey="Weder D">D Weder</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Radsak, K" uniqKey="Radsak K">K Radsak</name></author><author><name sortKey="Mertensmeier, I" uniqKey="Mertensmeier I">I Mertensmeier</name></author><author><name sortKey="Kaiser, C" uniqKey="Kaiser C">C Kaiser</name></author><author><name sortKey="Wagner, C" uniqKey="Wagner C">C Wagner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Radsak, K" uniqKey="Radsak K">K Radsak</name></author><author><name sortKey="Wiegandt, H" uniqKey="Wiegandt H">H Wiegandt</name></author><author><name sortKey="Unterdorfer, U" uniqKey="Unterdorfer U">U Unterdörfer</name></author><author><name sortKey="Wagner, C" uniqKey="Wagner C">C Wagner</name></author><author><name sortKey="Kaiser, Cj" uniqKey="Kaiser C">CJ Kaiser</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Radsak, K" uniqKey="Radsak K">K Radsak</name></author><author><name sortKey="Schmitz, B" uniqKey="Schmitz B">B Schmitz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rasmussen, L" uniqKey="Rasmussen L">L Rasmussen</name></author><author><name sortKey="Mullenax, J" uniqKey="Mullenax J">J Mullenax</name></author><author><name sortKey="Nelson, R" uniqKey="Nelson R">R Nelson</name></author><author><name sortKey="Merigan, Tc" uniqKey="Merigan T">TC Merigan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Saito, M" uniqKey="Saito M">M Saito</name></author><author><name sortKey="Saito, M" uniqKey="Saito M">M Saito</name></author><author><name sortKey="Rosenberg, A" uniqKey="Rosenberg A">A Rosenberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Scholtissek, C" uniqKey="Scholtissek C">C Scholtissek</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stinski, M" uniqKey="Stinski M">M Stinski</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tartakoff, Am" uniqKey="Tartakoff A">AM Tartakoff</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Towbin, H" uniqKey="Towbin H">H Towbin</name></author><author><name sortKey="Staehelin, T" uniqKey="Staehelin T">T Staehelin</name></author><author><name sortKey="Gordon, J" uniqKey="Gordon J">J Gordon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Drunen, Little" uniqKey="Van Drunen L">Little Van Drunen</name></author><author><name sortKey="Van Den Hurk, S" uniqKey="Van Den Hurk S">S Van den Hurk</name></author><author><name sortKey="Babiuk, La" uniqKey="Babiuk L">LA Babiuk</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Weder, D" uniqKey="Weder D">D Weder</name></author><author><name sortKey="Radsak, K" uniqKey="Radsak K">K Radsak</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Weiner, D" uniqKey="Weiner D">D Weiner</name></author><author><name sortKey="Gibson, W" uniqKey="Gibson W">W Gibson</name></author><author><name sortKey="Fields, Kl" uniqKey="Fields K">KL Fields</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Weissbach, A" uniqKey="Weissbach A">A Weissbach</name></author><author><name sortKey="Hong, S" uniqKey="Hong S">S Hong</name></author><author><name sortKey="Aucker, J" uniqKey="Aucker J">J Aucker</name></author><author><name sortKey="Muller, R" uniqKey="Muller R">R Muller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wenske, Ea" uniqKey="Wenske E">EA Wenske</name></author><author><name sortKey="Bratton, Mw" uniqKey="Bratton M">MW Bratton</name></author><author><name sortKey="Courtney, Rj" uniqKey="Courtney R">RJ Courtney</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Arch Virol</journal-id><journal-id journal-id-type="iso-abbrev">Arch. Virol</journal-id><journal-title-group><journal-title>Archives of Virology</journal-title></journal-title-group><issn pub-type="ppub">0304-8608</issn><issn pub-type="epub">1432-8798</issn><publisher><publisher-name>Springer-Verlag</publisher-name><publisher-loc>Vienna</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">3034210</article-id><article-id pub-id-type="pmc">7086728</article-id><article-id pub-id-type="publisher-id">BF01310716</article-id><article-id pub-id-type="doi">10.1007/BF01310716</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Papers</subject></subj-group></article-categories><title-group><article-title>Inhibition by monensin of human cytomegalovirus DNA replication</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Kaiser</surname><given-names>C. J.</given-names></name><xref ref-type="aff" rid="Aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Radsak</surname><given-names>K.</given-names></name><xref ref-type="aff" rid="Aff1"></xref></contrib><aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.10253.35</institution-id><institution-id institution-id-type="ISNI">0000000419369756</institution-id><institution>Zentrum für Hygiene und Medizinische Mikrobiologie,</institution><institution>Institut für Virologie der Philipps-Universität,</institution></institution-wrap>Marburg, Germany</aff></contrib-group><pub-date pub-type="ppub"><year>1987</year></pub-date><volume>94</volume><issue>3</issue><fpage>229</fpage><lpage>245</lpage><history><date date-type="accepted"><day>18</day><month>11</month><year>1986</year></date></history><permissions><copyright-statement>© Springer-Verlag 1987</copyright-statement><license><license-p>This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.</license-p></license></permissions><abstract id="Abs1"><title>Summary</title><p>Monensin, at concentrations which depended on the multiplicity of infection, was found to prevent DNA replication of human cytomegalovirus (HCMV) as well as production of viral progeny in human foreskin fibroblasts. The drug did not affect DNA replication of herpes simplex virus. Inhibition of consecutive HCMV DNA synthesis was also observed following delayed addition of the drug within 12–24 hours postinfection, but was fully reversible upon its removal. Viral replication proceeded, however, without impairment in cultures treated with monensin prior to infection. Induction of viral DNA polymerase activity was not impeded by the inhibitor. Analysis of protein- and glycoprotein synthesis revealed that monensin interfered with the production of a number of HCMV-specific polypeptides. Furthermore, evidence was obtained that the drug may hinder intracellular transport of a 135 kd glycopolypeptide.</p></abstract><kwd-group xml:lang="en"><title>Keywords</title><kwd>Infectious Disease</kwd><kwd>Polypeptide</kwd><kwd>Herpes Simplex</kwd><kwd>Viral Replication</kwd><kwd>Polymerase Activity</kwd></kwd-group><custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name><meta-value>© Springer-Verlag 1987</meta-value></custom-meta></custom-meta-group></article-meta></front><back><fn-group><fn><p>With 6 Figures</p></fn></fn-group><ref-list id="Bib1"><title>References</title><ref id="CR1"><label>1.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Bonner</surname><given-names>WM</given-names></name><name><surname>Laskey</surname><given-names>RA</given-names></name></person-group><article-title>A film detection method for tritium-labeled proteins and nucleic acids in polyacrylamide gels</article-title><source>Eur J Biochem</source><year>1974</year><volume>46</volume><fpage>83</fpage><lpage>88</lpage><pub-id pub-id-type="pmid">4850204</pub-id></element-citation></ref><ref id="CR2"><label>2.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Britt</surname><given-names>WJ</given-names></name><name><surname>Auger</surname><given-names>D</given-names></name></person-group><article-title>Synthesis and processing of the envelope gp 55–116 complex of human cytomegalovirus</article-title><source>J Virol</source><year>1986</year><volume>58</volume><fpage>185</fpage><lpage>191</lpage><pub-id pub-id-type="pmid">3005648</pub-id></element-citation></ref><ref id="CR3"><label>3.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Demarchi</surname><given-names>J</given-names></name><name><surname>Kaplan</surname><given-names>AS</given-names></name></person-group><article-title>Physiological state of embryonic human lung cells affect their response to human cytomegalovirus</article-title><source>J Virol</source><year>1977</year><volume>23</volume><fpage>126</fpage><lpage>132</lpage><pub-id pub-id-type="pmid">196097</pub-id></element-citation></ref><ref id="CR4"><label>4.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Fioretti</surname><given-names>A</given-names></name><name><surname>Furukawa</surname><given-names>T</given-names></name><name><surname>Santoli</surname><given-names>D</given-names></name><name><surname>Plotkin</surname><given-names>S</given-names></name></person-group><article-title>Nonproductive infection of guinea pig cells with human cytomegalovirus</article-title><source>J Virol</source><year>1973</year><volume>11</volume><fpage>998</fpage><lpage>1003</lpage><pub-id pub-id-type="pmid">4351465</pub-id></element-citation></ref><ref id="CR5"><label>5.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Furukawa</surname><given-names>T</given-names></name><name><surname>Fioretti</surname><given-names>A</given-names></name><name><surname>Plotkin</surname><given-names>S</given-names></name></person-group><article-title>Growth characteristics of cytomegalovirus in human fibroblasts with the demonstration of protein synthesis early in viral replication</article-title><source>J Virol</source><year>1973</year><volume>11</volume><fpage>991</fpage><lpage>997</lpage><pub-id pub-id-type="pmid">4351464</pub-id></element-citation></ref><ref id="CR6"><label>6.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Furukawa</surname><given-names>T</given-names></name><name><surname>Gönczöl</surname><given-names>E</given-names></name><name><surname>Starr</surname><given-names>S</given-names></name><name><surname>Tolpin</surname><given-names>MD</given-names></name><name><surname>Arbeter</surname><given-names>A</given-names></name><name><surname>Plotkin</surname><given-names>S</given-names></name></person-group><article-title>HCMV envelope antigens induce both humoral and cellular immunity in guinea pig</article-title><source>Proc Soc Exp Biol Med</source><year>1984</year><volume>175</volume><fpage>243</fpage><lpage>250</lpage><pub-id pub-id-type="pmid">6320210</pub-id></element-citation></ref><ref id="CR7"><label>7.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Furukawa</surname><given-names>T</given-names></name><name><surname>Tanaka</surname><given-names>S</given-names></name><name><surname>Plotkin</surname><given-names>S</given-names></name></person-group><article-title>Restricted growth of human cytomegalovirus in UV-irradiated WI-38 human fibroblasts</article-title><source>Proc Soc Exp Biol Med</source><year>1975</year><volume>148</volume><fpage>1249</fpage><lpage>1251</lpage><pub-id pub-id-type="pmid">165545</pub-id></element-citation></ref><ref id="CR8"><label>8.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Gallwitz</surname><given-names>D</given-names></name><name><surname>Bos</surname><given-names>E</given-names></name><name><surname>Stahl</surname><given-names>H</given-names></name></person-group><article-title>Translation of HeLa cell histone messenger RNA in cell-free protein synthesizing systems from rabbit reticulocytes, HeLa cells and wheat germ</article-title><source>Methods Cell Biol</source><year>1978</year><volume>19</volume><fpage>197</fpage><lpage>213</lpage><pub-id pub-id-type="pmid">692416</pub-id></element-citation></ref><ref id="CR9"><label>9.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Giles</surname><given-names>KW</given-names></name><name><surname>Myers</surname><given-names>A</given-names></name></person-group><article-title>An improved diphenylamine method for the estimation of deoxyribonucleic acid</article-title><source>Nature</source><year>1965</year><volume>206</volume><fpage>93</fpage><pub-id pub-id-type="pmid">14334364</pub-id></element-citation></ref><ref id="CR10"><label>10.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Hirai</surname><given-names>K</given-names></name><name><surname>Watanabe</surname><given-names>Y</given-names></name></person-group><article-title>Induction of alpha-type DNA polymerases in human cytomegalovirus-infected Wi-38 cells</article-title><source>Biochim Biophys Acta</source><year>1976</year><volume>447</volume><fpage>328</fpage><lpage>339</lpage><pub-id pub-id-type="pmid">184838</pub-id></element-citation></ref><ref id="CR11"><label>11.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Iwasaki</surname><given-names>Y</given-names></name><name><surname>Furukawa</surname><given-names>T</given-names></name><name><surname>Plotkin</surname><given-names>S</given-names></name><name><surname>Koprowski</surname><given-names>H</given-names></name></person-group><article-title>Ultrastructural study on the sequence of human cytomegalovirus infection in human diploid cells</article-title><source>Arch Virol</source><year>1973</year><volume>40</volume><fpage>311</fpage><lpage>324</lpage></element-citation></ref><ref id="CR12"><label>12.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Johnson</surname><given-names>DC</given-names></name><name><surname>Schlesinger</surname><given-names>MJ</given-names></name></person-group><article-title>Vesicular stomatitis virus and sindbis virus glycoprotein transport to the cell surface is inhibited by ionophores</article-title><source>Virology</source><year>1980</year><volume>103</volume><fpage>407</fpage><lpage>424</lpage><pub-id pub-id-type="pmid">6247822</pub-id></element-citation></ref><ref id="CR13"><label>13.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Johnson</surname><given-names>DC</given-names></name><name><surname>Spear</surname><given-names>PG</given-names></name></person-group><article-title>Monensin inhibits the processing of herpes simplex virus glycoproteins, their transport to the cell surface, and the egress of virions from infected cells</article-title><source>J Virol</source><year>1982</year><volume>43</volume><fpage>1102</fpage><lpage>1112</lpage><pub-id pub-id-type="pmid">6292453</pub-id></element-citation></ref><ref id="CR14"><label>14.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kerr</surname><given-names>CL</given-names></name><name><surname>Pennington</surname><given-names>TH</given-names></name></person-group><article-title>The effect of monensin on virion production and protein secretion in pseudorabies virus-infected cells</article-title><source>J Gen Virol</source><year>1984</year><volume>65</volume><fpage>1033</fpage><lpage>1041</lpage><pub-id pub-id-type="pmid">6327890</pub-id></element-citation></ref><ref id="CR15"><label>15.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kääriäinen</surname><given-names>L</given-names></name><name><surname>Hashimoto</surname><given-names>K</given-names></name><name><surname>Saraste</surname><given-names>J</given-names></name><name><surname>Virtanen</surname><given-names>I</given-names></name><name><surname>Penttinen</surname><given-names>K</given-names></name></person-group><article-title>Monensin and FCCP inhibit the intracellular transport of alphavirus membrane glycoproteins</article-title><source>J Cell Biol</source><year>1980</year><volume>87</volume><fpage>783</fpage><lpage>791</lpage><pub-id pub-id-type="pmid">6257729</pub-id></element-citation></ref><ref id="CR16"><label>16.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Lämmli</surname><given-names>UK</given-names></name></person-group><article-title>Cleavage of structural proteins during the assembly of the head of bacteriophage T 4</article-title><source>Nature</source><year>1970</year><volume>227</volume><fpage>680</fpage><lpage>685</lpage><pub-id pub-id-type="pmid">5432063</pub-id></element-citation></ref><ref id="CR17"><label>17.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Lowry</surname><given-names>OH</given-names></name><name><surname>Rosebrough</surname><given-names>NJ</given-names></name><name><surname>Farr</surname><given-names>AL</given-names></name><name><surname>Randall</surname><given-names>RJ</given-names></name></person-group><article-title>Protein measurement with the Folin phenol reagent</article-title><source>J Biol Chem</source><year>1951</year><volume>193</volume><fpage>265</fpage><lpage>275</lpage><pub-id pub-id-type="pmid">14907713</pub-id></element-citation></ref><ref id="CR18"><label>18.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ludwig</surname><given-names>H</given-names></name><name><surname>Rott</surname><given-names>R</given-names></name></person-group><article-title>Effect of 2-deoxy-D-glucose on herpesvirus-induced inhibition of cellular DNA synthesis</article-title><source>J Virol</source><year>1975</year><volume>26</volume><fpage>281</fpage><lpage>290</lpage></element-citation></ref><ref id="CR19"><label>19.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Luuokonen</surname><given-names>A</given-names></name><name><surname>Gahmberg</surname><given-names>CG</given-names></name><name><surname>Renkonen</surname><given-names>O</given-names></name></person-group><article-title>Surface labelling of Semliki forest virus glycoproteins using galactose oxidase</article-title><source>Virology</source><year>1977</year><volume>76</volume><fpage>55</fpage><lpage>59</lpage><pub-id pub-id-type="pmid">835244</pub-id></element-citation></ref><ref id="CR20"><label>20.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Musiani</surname><given-names>M</given-names></name><name><surname>Zerbini</surname><given-names>M</given-names></name></person-group><article-title>Influence of cell cycle on the efficiency of transfection with purified human cytomegalovirus DNA</article-title><source>Arch Virol</source><year>1984</year><volume>78</volume><fpage>287</fpage><lpage>292</lpage></element-citation></ref><ref id="CR21"><label>21.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Niemann</surname><given-names>H</given-names></name><name><surname>Boschek</surname><given-names>B</given-names></name><name><surname>Evans</surname><given-names>E</given-names></name><name><surname>Rosing</surname><given-names>M</given-names></name><name><surname>Tamura</surname><given-names>T</given-names></name><name><surname>Klenk</surname><given-names>HD</given-names></name></person-group><article-title>Post-translational glycosylation of corona-virus glycoprotein E 1: inhibition by monensin</article-title><source>EMBO J</source><year>1982</year><volume>1</volume><fpage>1499</fpage><lpage>1504</lpage><pub-id pub-id-type="pmid">6327272</pub-id></element-citation></ref><ref id="CR22"><label>22.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Norrild</surname><given-names>B</given-names></name><name><surname>Virtanen</surname><given-names>I</given-names></name><name><surname>Pedersen</surname><given-names>B</given-names></name><name><surname>Pereira</surname><given-names>L</given-names></name></person-group><article-title>Requirements for transport of HSV-1 glycoproteins to the cell surface membrane of human fibroblasts and vero cells</article-title><source>Arch Virol</source><year>1983</year><volume>77</volume><fpage>155</fpage><lpage>166</lpage><pub-id pub-id-type="pmid">6314934</pub-id></element-citation></ref><ref id="CR23"><label>23.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Nowak</surname><given-names>B</given-names></name><name><surname>Sullivan</surname><given-names>C</given-names></name><name><surname>Sarnow</surname><given-names>P</given-names></name><name><surname>Thomas</surname><given-names>R</given-names></name><name><surname>Bricout</surname><given-names>F</given-names></name><name><surname>Nicolas</surname><given-names>JC</given-names></name><name><surname>Fleckenstein</surname><given-names>B</given-names></name><name><surname>Levine</surname><given-names>AJ</given-names></name></person-group><article-title>Characterisation of monoclonal antibodies and polyclonal immune sera directed against human cytomegalovirus virion proteins</article-title><source>Virology</source><year>1984</year><volume>132</volume><fpage>325</fpage><lpage>338</lpage><pub-id pub-id-type="pmid">6322416</pub-id></element-citation></ref><ref id="CR24"><label>24.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Payne</surname><given-names>LG</given-names></name><name><surname>Kristensson</surname><given-names>K</given-names></name></person-group><article-title>The effect of cytochalasin D and monensin on enveloped vaccinia virus release</article-title><source>Arch Virol</source><year>1982</year><volume>74</volume><fpage>11</fpage><lpage>20</lpage><pub-id pub-id-type="pmid">6891579</pub-id></element-citation></ref><ref id="CR25"><label>25.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Pereira</surname><given-names>L</given-names></name><name><surname>Hoffman</surname><given-names>M</given-names></name><name><surname>Tatsuno</surname><given-names>M</given-names></name><name><surname>Dondero</surname><given-names>D</given-names></name></person-group><article-title>Polymorphism of human cytomegalovirus glycoproteins characterized by monoclonal antibodies</article-title><source>Virology</source><year>1984</year><volume>139</volume><fpage>73</fpage><lpage>86</lpage><pub-id pub-id-type="pmid">6208685</pub-id></element-citation></ref><ref id="CR26"><label>26.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Radsak</surname><given-names>K</given-names></name></person-group><article-title>Effect of herpes simplex virus type 1 infection on the cellular DNA polymerase activities of mouse cell cultures</article-title><source>J Gen Virol</source><year>1978</year><volume>41</volume><fpage>479</fpage><lpage>491</lpage><pub-id pub-id-type="pmid">217947</pub-id></element-citation></ref><ref id="CR27"><label>27.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Radsak</surname><given-names>K</given-names></name><name><surname>Furukawa</surname><given-names>T</given-names></name><name><surname>Plotkin</surname><given-names>S</given-names></name></person-group><article-title>DNA synthesis in chromatin preparations from human fibroblasts infected by cytomegalovirus</article-title><source>Arch Virol</source><year>1980</year><volume>65</volume><fpage>45</fpage><lpage>54</lpage><pub-id pub-id-type="pmid">6252865</pub-id></element-citation></ref><ref id="CR28"><label>28.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Radsak</surname><given-names>K</given-names></name><name><surname>Weder</surname><given-names>D</given-names></name></person-group><article-title>Effect of 2-deoxy-D-glucose on cytomegalovirus-induced DNA synthesis in human fibroblasts</article-title><source>J Gen Virol</source><year>1981</year><volume>57</volume><fpage>33</fpage><lpage>42</lpage><pub-id pub-id-type="pmid">6275020</pub-id></element-citation></ref><ref id="CR29"><label>29.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Radsak</surname><given-names>K</given-names></name><name><surname>Mertensmeier</surname><given-names>I</given-names></name><name><surname>Kaiser</surname><given-names>C</given-names></name><name><surname>Wagner</surname><given-names>C</given-names></name></person-group><article-title>Distinction of viral and host-derived glycopolypeptides induced by “early” functions of human cytomegalovirus</article-title><source>Arch Virol</source><year>1985</year><volume>85</volume><fpage>217</fpage><lpage>230</lpage><pub-id pub-id-type="pmid">2992419</pub-id></element-citation></ref><ref id="CR30"><label>30.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Radsak</surname><given-names>K</given-names></name><name><surname>Wiegandt</surname><given-names>H</given-names></name><name><surname>Unterdörfer</surname><given-names>U</given-names></name><name><surname>Wagner</surname><given-names>C</given-names></name><name><surname>Kaiser</surname><given-names>CJ</given-names></name></person-group><article-title>Sodium butyrate selectivly inhibits host cell glycoprotein synthesis in human fibroblasts infected with cytomegalovirus</article-title><source>Biosci Rep</source><year>1985</year><volume>5</volume><fpage>589</fpage><lpage>599</lpage><pub-id pub-id-type="pmid">2994773</pub-id></element-citation></ref><ref id="CR31"><label>31.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Radsak</surname><given-names>K</given-names></name><name><surname>Schmitz</surname><given-names>B</given-names></name></person-group><article-title>Unimpaired histon synthesis in human fibroblasts infected by human cytomegalovirus</article-title><source>Med Microbiol Immunol (Berl)</source><year>1980</year><volume>168</volume><fpage>63</fpage><lpage>72</lpage><pub-id pub-id-type="pmid">6247630</pub-id></element-citation></ref><ref id="CR32"><label>32.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Rasmussen</surname><given-names>L</given-names></name><name><surname>Mullenax</surname><given-names>J</given-names></name><name><surname>Nelson</surname><given-names>R</given-names></name><name><surname>Merigan</surname><given-names>TC</given-names></name></person-group><article-title>Viral polypeptides detected by a complement-dependent neutralizing murine monoclonal antibody to human cytomegalovirus</article-title><source>J Virol</source><year>1985</year><volume>55</volume><fpage>274</fpage><lpage>280</lpage><pub-id pub-id-type="pmid">2410626</pub-id></element-citation></ref><ref id="CR33"><label>33.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Saito</surname><given-names>M</given-names></name><name><surname>Saito</surname><given-names>M</given-names></name><name><surname>Rosenberg</surname><given-names>A</given-names></name></person-group><article-title>Action of monensin, a monovalent cationophore, on cultured human fibroblasts: evidence that it induces high cellular accumulation of glucosyl- and lactosylceramide (gluco- and lactocerebroside)</article-title><source>Biochemistry</source><year>1984</year><volume>23</volume><fpage>1043</fpage><lpage>1046</lpage><pub-id pub-id-type="pmid">6712936</pub-id></element-citation></ref><ref id="CR34"><label>34.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Scholtissek</surname><given-names>C</given-names></name></person-group><article-title>Inhibition of multiplication of enveloped viruses by glucose derivatives</article-title><source>Curr Top Microbiol Immunol</source><year>1975</year><volume>70</volume><fpage>101</fpage><lpage>119</lpage><pub-id pub-id-type="pmid">808397</pub-id></element-citation></ref><ref id="CR35"><label>35.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Stinski</surname><given-names>M</given-names></name></person-group><article-title>synthesis of proteins and glycoproteins in cells infected with human cytomegalovirus</article-title><source>J Virol</source><year>1977</year><volume>23</volume><fpage>1023</fpage><lpage>1034</lpage></element-citation></ref><ref id="CR36"><label>36.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Tartakoff</surname><given-names>AM</given-names></name></person-group><article-title>Pertubation of vesicular traffic with the carboxylic ionophore monensin</article-title><source>Cell</source><year>1983</year><volume>32</volume><fpage>1026</fpage><lpage>1028</lpage><pub-id pub-id-type="pmid">6340834</pub-id></element-citation></ref><ref id="CR37"><label>37.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Towbin</surname><given-names>H</given-names></name><name><surname>Staehelin</surname><given-names>T</given-names></name><name><surname>Gordon</surname><given-names>J</given-names></name></person-group><article-title>Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications</article-title><source>Proc Natl Acad Sci USA</source><year>1979</year><volume>76</volume><fpage>4350</fpage><lpage>4354</lpage><pub-id pub-id-type="pmid">388439</pub-id></element-citation></ref><ref id="CR38"><label>38.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Van Drunen</surname><given-names>Little</given-names></name><name><surname>Van den Hurk</surname><given-names>S</given-names></name><name><surname>Babiuk</surname><given-names>LA</given-names></name></person-group><article-title>Effect of tunicamycin and monensin on biosynthesis, transport and maturation of bovine herpesvirus type 1 glycoproteins</article-title><source>Virology</source><year>1985</year><volume>143</volume><fpage>104</fpage><lpage>118</lpage><pub-id pub-id-type="pmid">2997997</pub-id></element-citation></ref><ref id="CR39"><label>39.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Weder</surname><given-names>D</given-names></name><name><surname>Radsak</surname><given-names>K</given-names></name></person-group><article-title>Induction of a host-specific chromatin-associated glycopolypeptide by human cytomegalovirus</article-title><source>J Gen Virol</source><year>1983</year><volume>64</volume><fpage>2749</fpage><lpage>2761</lpage><pub-id pub-id-type="pmid">6319557</pub-id></element-citation></ref><ref id="CR40"><label>40.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Weiner</surname><given-names>D</given-names></name><name><surname>Gibson</surname><given-names>W</given-names></name><name><surname>Fields</surname><given-names>KL</given-names></name></person-group><article-title>Anti-complement immunofluorescence establishes nuclear localisation of human cytomegalovirus matrix protein</article-title><source>Virology</source><year>1985</year><volume>147</volume><fpage>19</fpage><lpage>28</lpage><pub-id pub-id-type="pmid">2998062</pub-id></element-citation></ref><ref id="CR41"><label>41.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Weissbach</surname><given-names>A</given-names></name><name><surname>Hong</surname><given-names>S</given-names></name><name><surname>Aucker</surname><given-names>J</given-names></name><name><surname>Muller</surname><given-names>R</given-names></name></person-group><article-title>Characterization of herpes simplex virus induced deoxyribonucleic acid polymerase</article-title><source>J Biol Chem</source><year>1973</year><volume>248</volume><fpage>6270</fpage><lpage>6277</lpage><pub-id pub-id-type="pmid">4354205</pub-id></element-citation></ref><ref id="CR42"><label>42.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Wenske</surname><given-names>EA</given-names></name><name><surname>Bratton</surname><given-names>MW</given-names></name><name><surname>Courtney</surname><given-names>RJ</given-names></name></person-group><article-title>Endo-β-N-acetylglucosaminidase H sensitivity of precursor to herpes simplex virus type 1 glycoproteins gB and gC</article-title><source>J Virol</source><year>1982</year><volume>44</volume><fpage>241</fpage><lpage>248</lpage><pub-id pub-id-type="pmid">6292487</pub-id></element-citation></ref></ref-list></back></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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