Identification of Leukotoxin and other vaccine candidate proteins in a Mannheimia haemolytica commercial antigen
Identifieur interne : 000643 ( Ncbi/Curation ); précédent : 000642; suivant : 000644Identification of Leukotoxin and other vaccine candidate proteins in a Mannheimia haemolytica commercial antigen
Auteurs : Paula Tucci [Uruguay] ; Ver Nica Estevez [Uruguay] ; Lorena Becco [Uruguay] ; Florencia Cabrera-Cabrera [Uruguay] ; Germán Grotiuz [Uruguay] ; Eduardo Reolon [Uruguay] ; M Nica Marín [Uruguay]Source :
- Heliyon [ 2405-8440 ] ; 2016.
Abstract
Bovine Respiratory Disease is the most costly disease that affects beef and dairy cattle industry. Its etiology is multifactorial, arising from predisposing environmental stress conditions as well as the action of several different respiratory pathogens. This situation has hindered the development of effective control strategies. Although different type of vaccines are available, many currently marketed vaccines are based on inactivated cultures of the main viral and bacterial agents involved in this pathology. The molecular composition of commercial veterinary vaccines is a critical issue. The present work aims to define at the proteomic level the most relevant valence of a line of commercial respiratory vaccines widely used in Central and South America. Since
Url:
DOI: 10.1016/j.heliyon.2016.e00158
PubMed: 27699279
PubMed Central: 5035357
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000874
- to stream Pmc, to step Curation: Pour aller vers cette notice dans l'étape Curation :000874
- to stream Pmc, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000477
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :000643
Links to Exploration step
PMC:5035357Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Identification of Leukotoxin and other vaccine candidate proteins in a <italic>Mannheimia haemolytica</italic>
commercial antigen</title>
<author><name sortKey="Tucci, Paula" sort="Tucci, Paula" uniqKey="Tucci P" first="Paula" last="Tucci">Paula Tucci</name>
<affiliation wicri:level="1"><nlm:aff id="aff0005">Biotechnology Division, Laboratorios Celsius, S.A. Avenida Italia 6201, Montevideo, Uruguay</nlm:aff>
<country xml:lang="fr">Uruguay</country>
<wicri:regionArea>Biotechnology Division, Laboratorios Celsius, S.A. Avenida Italia 6201, Montevideo</wicri:regionArea>
<wicri:noRegion>Montevideo</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff0010">Biochemistry-Molecular Biology Section, Faculty of Sciences, Universidad de la República, Iguá 4225, Montevideo, Uruguay</nlm:aff>
<country xml:lang="fr">Uruguay</country>
<wicri:regionArea>Biochemistry-Molecular Biology Section, Faculty of Sciences, Universidad de la República, Iguá 4225, Montevideo</wicri:regionArea>
<wicri:noRegion>Montevideo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Estevez, Ver Nica" sort="Estevez, Ver Nica" uniqKey="Estevez V" first="Ver Nica" last="Estevez">Ver Nica Estevez</name>
<affiliation wicri:level="1"><nlm:aff id="aff0005">Biotechnology Division, Laboratorios Celsius, S.A. Avenida Italia 6201, Montevideo, Uruguay</nlm:aff>
<country xml:lang="fr">Uruguay</country>
<wicri:regionArea>Biotechnology Division, Laboratorios Celsius, S.A. Avenida Italia 6201, Montevideo</wicri:regionArea>
<wicri:noRegion>Montevideo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Becco, Lorena" sort="Becco, Lorena" uniqKey="Becco L" first="Lorena" last="Becco">Lorena Becco</name>
<affiliation wicri:level="1"><nlm:aff id="aff0005">Biotechnology Division, Laboratorios Celsius, S.A. Avenida Italia 6201, Montevideo, Uruguay</nlm:aff>
<country xml:lang="fr">Uruguay</country>
<wicri:regionArea>Biotechnology Division, Laboratorios Celsius, S.A. Avenida Italia 6201, Montevideo</wicri:regionArea>
<wicri:noRegion>Montevideo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Cabrera Cabrera, Florencia" sort="Cabrera Cabrera, Florencia" uniqKey="Cabrera Cabrera F" first="Florencia" last="Cabrera-Cabrera">Florencia Cabrera-Cabrera</name>
<affiliation wicri:level="1"><nlm:aff id="aff0010">Biochemistry-Molecular Biology Section, Faculty of Sciences, Universidad de la República, Iguá 4225, Montevideo, Uruguay</nlm:aff>
<country xml:lang="fr">Uruguay</country>
<wicri:regionArea>Biochemistry-Molecular Biology Section, Faculty of Sciences, Universidad de la República, Iguá 4225, Montevideo</wicri:regionArea>
<wicri:noRegion>Montevideo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Grotiuz, German" sort="Grotiuz, German" uniqKey="Grotiuz G" first="Germán" last="Grotiuz">Germán Grotiuz</name>
<affiliation wicri:level="1"><nlm:aff id="aff0015">Virbac Uruguay, S.A. Avda. Millán 4175, Montevideo, Uruguay</nlm:aff>
<country xml:lang="fr">Uruguay</country>
<wicri:regionArea>Virbac Uruguay, S.A. Avda. Millán 4175, Montevideo</wicri:regionArea>
<wicri:noRegion>Montevideo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Reolon, Eduardo" sort="Reolon, Eduardo" uniqKey="Reolon E" first="Eduardo" last="Reolon">Eduardo Reolon</name>
<affiliation wicri:level="1"><nlm:aff id="aff0015">Virbac Uruguay, S.A. Avda. Millán 4175, Montevideo, Uruguay</nlm:aff>
<country xml:lang="fr">Uruguay</country>
<wicri:regionArea>Virbac Uruguay, S.A. Avda. Millán 4175, Montevideo</wicri:regionArea>
<wicri:noRegion>Montevideo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Marin, M Nica" sort="Marin, M Nica" uniqKey="Marin M" first="M Nica" last="Marín">M Nica Marín</name>
<affiliation wicri:level="1"><nlm:aff id="aff0010">Biochemistry-Molecular Biology Section, Faculty of Sciences, Universidad de la República, Iguá 4225, Montevideo, Uruguay</nlm:aff>
<country xml:lang="fr">Uruguay</country>
<wicri:regionArea>Biochemistry-Molecular Biology Section, Faculty of Sciences, Universidad de la República, Iguá 4225, Montevideo</wicri:regionArea>
<wicri:noRegion>Montevideo</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">27699279</idno>
<idno type="pmc">5035357</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035357</idno>
<idno type="RBID">PMC:5035357</idno>
<idno type="doi">10.1016/j.heliyon.2016.e00158</idno>
<date when="2016">2016</date>
<idno type="wicri:Area/Pmc/Corpus">000874</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000874</idno>
<idno type="wicri:Area/Pmc/Curation">000874</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000874</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000477</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000477</idno>
<idno type="wicri:Area/Ncbi/Merge">000643</idno>
<idno type="wicri:Area/Ncbi/Curation">000643</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Identification of Leukotoxin and other vaccine candidate proteins in a <italic>Mannheimia haemolytica</italic>
commercial antigen</title>
<author><name sortKey="Tucci, Paula" sort="Tucci, Paula" uniqKey="Tucci P" first="Paula" last="Tucci">Paula Tucci</name>
<affiliation wicri:level="1"><nlm:aff id="aff0005">Biotechnology Division, Laboratorios Celsius, S.A. Avenida Italia 6201, Montevideo, Uruguay</nlm:aff>
<country xml:lang="fr">Uruguay</country>
<wicri:regionArea>Biotechnology Division, Laboratorios Celsius, S.A. Avenida Italia 6201, Montevideo</wicri:regionArea>
<wicri:noRegion>Montevideo</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff0010">Biochemistry-Molecular Biology Section, Faculty of Sciences, Universidad de la República, Iguá 4225, Montevideo, Uruguay</nlm:aff>
<country xml:lang="fr">Uruguay</country>
<wicri:regionArea>Biochemistry-Molecular Biology Section, Faculty of Sciences, Universidad de la República, Iguá 4225, Montevideo</wicri:regionArea>
<wicri:noRegion>Montevideo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Estevez, Ver Nica" sort="Estevez, Ver Nica" uniqKey="Estevez V" first="Ver Nica" last="Estevez">Ver Nica Estevez</name>
<affiliation wicri:level="1"><nlm:aff id="aff0005">Biotechnology Division, Laboratorios Celsius, S.A. Avenida Italia 6201, Montevideo, Uruguay</nlm:aff>
<country xml:lang="fr">Uruguay</country>
<wicri:regionArea>Biotechnology Division, Laboratorios Celsius, S.A. Avenida Italia 6201, Montevideo</wicri:regionArea>
<wicri:noRegion>Montevideo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Becco, Lorena" sort="Becco, Lorena" uniqKey="Becco L" first="Lorena" last="Becco">Lorena Becco</name>
<affiliation wicri:level="1"><nlm:aff id="aff0005">Biotechnology Division, Laboratorios Celsius, S.A. Avenida Italia 6201, Montevideo, Uruguay</nlm:aff>
<country xml:lang="fr">Uruguay</country>
<wicri:regionArea>Biotechnology Division, Laboratorios Celsius, S.A. Avenida Italia 6201, Montevideo</wicri:regionArea>
<wicri:noRegion>Montevideo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Cabrera Cabrera, Florencia" sort="Cabrera Cabrera, Florencia" uniqKey="Cabrera Cabrera F" first="Florencia" last="Cabrera-Cabrera">Florencia Cabrera-Cabrera</name>
<affiliation wicri:level="1"><nlm:aff id="aff0010">Biochemistry-Molecular Biology Section, Faculty of Sciences, Universidad de la República, Iguá 4225, Montevideo, Uruguay</nlm:aff>
<country xml:lang="fr">Uruguay</country>
<wicri:regionArea>Biochemistry-Molecular Biology Section, Faculty of Sciences, Universidad de la República, Iguá 4225, Montevideo</wicri:regionArea>
<wicri:noRegion>Montevideo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Grotiuz, German" sort="Grotiuz, German" uniqKey="Grotiuz G" first="Germán" last="Grotiuz">Germán Grotiuz</name>
<affiliation wicri:level="1"><nlm:aff id="aff0015">Virbac Uruguay, S.A. Avda. Millán 4175, Montevideo, Uruguay</nlm:aff>
<country xml:lang="fr">Uruguay</country>
<wicri:regionArea>Virbac Uruguay, S.A. Avda. Millán 4175, Montevideo</wicri:regionArea>
<wicri:noRegion>Montevideo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Reolon, Eduardo" sort="Reolon, Eduardo" uniqKey="Reolon E" first="Eduardo" last="Reolon">Eduardo Reolon</name>
<affiliation wicri:level="1"><nlm:aff id="aff0015">Virbac Uruguay, S.A. Avda. Millán 4175, Montevideo, Uruguay</nlm:aff>
<country xml:lang="fr">Uruguay</country>
<wicri:regionArea>Virbac Uruguay, S.A. Avda. Millán 4175, Montevideo</wicri:regionArea>
<wicri:noRegion>Montevideo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Marin, M Nica" sort="Marin, M Nica" uniqKey="Marin M" first="M Nica" last="Marín">M Nica Marín</name>
<affiliation wicri:level="1"><nlm:aff id="aff0010">Biochemistry-Molecular Biology Section, Faculty of Sciences, Universidad de la República, Iguá 4225, Montevideo, Uruguay</nlm:aff>
<country xml:lang="fr">Uruguay</country>
<wicri:regionArea>Biochemistry-Molecular Biology Section, Faculty of Sciences, Universidad de la República, Iguá 4225, Montevideo</wicri:regionArea>
<wicri:noRegion>Montevideo</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Heliyon</title>
<idno type="eISSN">2405-8440</idno>
<imprint><date when="2016">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Bovine Respiratory Disease is the most costly disease that affects beef and dairy cattle industry. Its etiology is multifactorial, arising from predisposing environmental stress conditions as well as the action of several different respiratory pathogens. This situation has hindered the development of effective control strategies. Although different type of vaccines are available, many currently marketed vaccines are based on inactivated cultures of the main viral and bacterial agents involved in this pathology. The molecular composition of commercial veterinary vaccines is a critical issue. The present work aims to define at the proteomic level the most relevant valence of a line of commercial respiratory vaccines widely used in Central and South America. Since <italic>Mannheimia haemolytica</italic>
is responsible for most of the disease associated morbid-mortality, we focused on the main proteins secreted by this pathogen, in particular Leukotoxin A, its main virulence factor. By Western blot analysis and mass spectrometry, Leukotoxin A was identified as a major component of <italic>M. haemolytica</italic>
culture supernatants. We also identified other ten <italic>M. haemolytica</italic>
proteins, including outer membrane proteins, periplasmic transmembrane solute transporters and iron binding proteins, which are relevant to achieve protective immunity against the pathogen. This work allowed a detailed molecular characterization of this vaccine component, providing evidence of its quality and efficacy. Furthermore, our results contributed to the identification of several proteins of interest as subunit vaccine candidates.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Al Ghamdi, G M" uniqKey="Al Ghamdi G">G.M. Al-Ghamdi</name>
</author>
<author><name sortKey="Ames, T R" uniqKey="Ames T">T.R. Ames</name>
</author>
<author><name sortKey="Baker, J C" uniqKey="Baker J">J.C. Baker</name>
</author>
<author><name sortKey="Walker, R" uniqKey="Walker R">R. Walker</name>
</author>
<author><name sortKey="Chase, C C" uniqKey="Chase C">C.C. Chase</name>
</author>
<author><name sortKey="Frank, G H" uniqKey="Frank G">G.H. Frank</name>
</author>
<author><name sortKey="Maheswaran, S K" uniqKey="Maheswaran S">S.K. Maheswaran</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Alvarez, A H" uniqKey="Alvarez A">A.H. Alvarez</name>
</author>
<author><name sortKey="Gutierrez Ortega, A" uniqKey="Gutierrez Ortega A">A. Gutierrez-Ortega</name>
</author>
<author><name sortKey="Hernandez Gutierrez, R" uniqKey="Hernandez Gutierrez R">R. Hernandez-Gutierrez</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ausubel, F M" uniqKey="Ausubel F">F.M. Ausubel</name>
</author>
<author><name sortKey="Brent, R" uniqKey="Brent R">R. Brent</name>
</author>
<author><name sortKey="Kingston, R E" uniqKey="Kingston R">R.E. Kingston</name>
</author>
<author><name sortKey="Moore, D D" uniqKey="Moore D">D.D. Moore</name>
</author>
<author><name sortKey="Seidman, J G" uniqKey="Seidman J">J.G. Seidman</name>
</author>
<author><name sortKey="Smith, J A" uniqKey="Smith J">J.A. Smith</name>
</author>
<author><name sortKey="Struhl, K" uniqKey="Struhl K">K. Struhl</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Autio, T" uniqKey="Autio T">T. Autio</name>
</author>
<author><name sortKey="Pohjanvirta, T" uniqKey="Pohjanvirta T">T. Pohjanvirta</name>
</author>
<author><name sortKey="Holopainen, R" uniqKey="Holopainen R">R. Holopainen</name>
</author>
<author><name sortKey="Rikula, U" uniqKey="Rikula U">U. Rikula</name>
</author>
<author><name sortKey="Pentikainen, J" uniqKey="Pentikainen J">J. Pentikainen</name>
</author>
<author><name sortKey="Huovilainen, A" uniqKey="Huovilainen A">A. Huovilainen</name>
</author>
<author><name sortKey="Rusanen, H" uniqKey="Rusanen H">H. Rusanen</name>
</author>
<author><name sortKey="Soveri, T" uniqKey="Soveri T">T. Soveri</name>
</author>
<author><name sortKey="Sihvonen, L" uniqKey="Sihvonen L">L. Sihvonen</name>
</author>
<author><name sortKey="Pelkonen, S" uniqKey="Pelkonen S">S. Pelkonen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ayalew, S" uniqKey="Ayalew S">S. Ayalew</name>
</author>
<author><name sortKey="Confer, A W" uniqKey="Confer A">A.W. Confer</name>
</author>
<author><name sortKey="Hartson, S D" uniqKey="Hartson S">S.D. Hartson</name>
</author>
<author><name sortKey="Shrestha, B" uniqKey="Shrestha B">B. Shrestha</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ayalew, S" uniqKey="Ayalew S">S. Ayalew</name>
</author>
<author><name sortKey="Shrestha, B" uniqKey="Shrestha B">B. Shrestha</name>
</author>
<author><name sortKey="Montelongo, M" uniqKey="Montelongo M">M. Montelongo</name>
</author>
<author><name sortKey="Wilson, A E" uniqKey="Wilson A">A.E. Wilson</name>
</author>
<author><name sortKey="Confer, A W" uniqKey="Confer A">A.W. Confer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Confer, A W" uniqKey="Confer A">A.W. Confer</name>
</author>
<author><name sortKey="Ayalew, S" uniqKey="Ayalew S">S. Ayalew</name>
</author>
<author><name sortKey="Montelongo, M" uniqKey="Montelongo M">M. Montelongo</name>
</author>
<author><name sortKey="Step, D L" uniqKey="Step D">D.L. Step</name>
</author>
<author><name sortKey="Wray, J H" uniqKey="Wray J">J.H. Wray</name>
</author>
<author><name sortKey="Hansen, R D" uniqKey="Hansen R">R.D. Hansen</name>
</author>
<author><name sortKey="Panciera, R J" uniqKey="Panciera R">R.J. Panciera</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Confer, A W" uniqKey="Confer A">A.W. Confer</name>
</author>
<author><name sortKey="Mccraw, R D" uniqKey="Mccraw R">R.D. McCraw</name>
</author>
<author><name sortKey="Durham, J A" uniqKey="Durham J">J.A. Durham</name>
</author>
<author><name sortKey="Morton, R J" uniqKey="Morton R">R.J. Morton</name>
</author>
<author><name sortKey="Panciera, R J" uniqKey="Panciera R">R.J. Panciera</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Conlon, J A" uniqKey="Conlon J">J.A. Conlon</name>
</author>
<author><name sortKey="Shewen, P E" uniqKey="Shewen P">P.E. Shewen</name>
</author>
<author><name sortKey="Lo, R Y" uniqKey="Lo R">R.Y. Lo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Corbeil, L B" uniqKey="Corbeil L">L.B. Corbeil</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chang, Y F" uniqKey="Chang Y">Y.F. Chang</name>
</author>
<author><name sortKey="Young, R" uniqKey="Young R">R. Young</name>
</author>
<author><name sortKey="Post, D" uniqKey="Post D">D. Post</name>
</author>
<author><name sortKey="Struck, D K" uniqKey="Struck D">D.K. Struck</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Dabo, S M" uniqKey="Dabo S">S.M. Dabo</name>
</author>
<author><name sortKey="Taylor, J D" uniqKey="Taylor J">J.D. Taylor</name>
</author>
<author><name sortKey="Confer, A W" uniqKey="Confer A">A.W. Confer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Derzelle, S" uniqKey="Derzelle S">S. Derzelle</name>
</author>
<author><name sortKey="Bolotin, A" uniqKey="Bolotin A">A. Bolotin</name>
</author>
<author><name sortKey="Mistou, M Y" uniqKey="Mistou M">M.Y. Mistou</name>
</author>
<author><name sortKey="Rul, F" uniqKey="Rul F">F. Rul</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Edwards, T A" uniqKey="Edwards T">T.A. Edwards</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Eidam, C" uniqKey="Eidam C">C. Eidam</name>
</author>
<author><name sortKey="Poehlein, A" uniqKey="Poehlein A">A. Poehlein</name>
</author>
<author><name sortKey="Brenner Michael, G" uniqKey="Brenner Michael G">G. Brenner Michael</name>
</author>
<author><name sortKey="Kadlec, K" uniqKey="Kadlec K">K. Kadlec</name>
</author>
<author><name sortKey="Liesegang, H" uniqKey="Liesegang H">H. Liesegang</name>
</author>
<author><name sortKey="Brzuszkiewicz, E" uniqKey="Brzuszkiewicz E">E. Brzuszkiewicz</name>
</author>
<author><name sortKey="Daniel, R" uniqKey="Daniel R">R. Daniel</name>
</author>
<author><name sortKey="Sweeney, M T" uniqKey="Sweeney M">M.T. Sweeney</name>
</author>
<author><name sortKey="Murray, R W" uniqKey="Murray R">R.W. Murray</name>
</author>
<author><name sortKey="Watts, J L" uniqKey="Watts J">J.L. Watts</name>
</author>
<author><name sortKey="Schwarz, S" uniqKey="Schwarz S">S. Schwarz</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Fulton, R W" uniqKey="Fulton R">R.W. Fulton</name>
</author>
<author><name sortKey="Purdy, C W" uniqKey="Purdy C">C.W. Purdy</name>
</author>
<author><name sortKey="Confer, A W" uniqKey="Confer A">A.W. Confer</name>
</author>
<author><name sortKey="Saliki, J T" uniqKey="Saliki J">J.T. Saliki</name>
</author>
<author><name sortKey="Loan, R W" uniqKey="Loan R">R.W. Loan</name>
</author>
<author><name sortKey="Briggs, R E" uniqKey="Briggs R">R.E. Briggs</name>
</author>
<author><name sortKey="Burge, L J" uniqKey="Burge L">L.J. Burge</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Garmory, H S" uniqKey="Garmory H">H.S. Garmory</name>
</author>
<author><name sortKey="Titball, R W" uniqKey="Titball R">R.W. Titball</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gershwin, L J" uniqKey="Gershwin L">L.J. Gershwin</name>
</author>
<author><name sortKey="Gunther, R A" uniqKey="Gunther R">R.A. Gunther</name>
</author>
<author><name sortKey="Anderson, M L" uniqKey="Anderson M">M.L. Anderson</name>
</author>
<author><name sortKey="Woolums, A R" uniqKey="Woolums A">A.R. Woolums</name>
</author>
<author><name sortKey="Mcarthur Vaughan, K" uniqKey="Mcarthur Vaughan K">K. McArthur-Vaughan</name>
</author>
<author><name sortKey="Randel, K E" uniqKey="Randel K">K.E. Randel</name>
</author>
<author><name sortKey="Boyle, G A" uniqKey="Boyle G">G.A. Boyle</name>
</author>
<author><name sortKey="Friebertshauser, K E" uniqKey="Friebertshauser K">K.E. Friebertshauser</name>
</author>
<author><name sortKey="Mcinturff, P S" uniqKey="Mcinturff P">P.S. McInturff</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Guzman Brambila, C" uniqKey="Guzman Brambila C">C. Guzman-Brambila</name>
</author>
<author><name sortKey="Quintero Fabian, S" uniqKey="Quintero Fabian S">S. Quintero-Fabian</name>
</author>
<author><name sortKey="Gonzalez Castillo, C" uniqKey="Gonzalez Castillo C">C. Gonzalez-Castillo</name>
</author>
<author><name sortKey="De Obeso Fernandez Del Valle, A" uniqKey="De Obeso Fernandez Del Valle A">A. de Obeso-Fernandez del Valle</name>
</author>
<author><name sortKey="Flores Samaniego, B" uniqKey="Flores Samaniego B">B. Flores-Samaniego</name>
</author>
<author><name sortKey="De La Mora, G" uniqKey="De La Mora G">G. de la Mora</name>
</author>
<author><name sortKey="Rojas Mayorquin, A E" uniqKey="Rojas Mayorquin A">A.E. Rojas-Mayorquin</name>
</author>
<author><name sortKey="Ortuno Sahagun, D" uniqKey="Ortuno Sahagun D">D. Ortuno-Sahagun</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Harhay, G P" uniqKey="Harhay G">G.P. Harhay</name>
</author>
<author><name sortKey="Koren, S" uniqKey="Koren S">S. Koren</name>
</author>
<author><name sortKey="Phillippy, A M" uniqKey="Phillippy A">A.M. Phillippy</name>
</author>
<author><name sortKey="Mcvey, D S" uniqKey="Mcvey D">D.S. McVey</name>
</author>
<author><name sortKey="Kuszak, J" uniqKey="Kuszak J">J. Kuszak</name>
</author>
<author><name sortKey="Clawson, M L" uniqKey="Clawson M">M.L. Clawson</name>
</author>
<author><name sortKey="Harhay, D M" uniqKey="Harhay D">D.M. Harhay</name>
</author>
<author><name sortKey="Heaton, M P" uniqKey="Heaton M">M.P. Heaton</name>
</author>
<author><name sortKey="Chitko Mckown, C G" uniqKey="Chitko Mckown C">C.G. Chitko-McKown</name>
</author>
<author><name sortKey="Smith, T P" uniqKey="Smith T">T.P. Smith</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hauglund, M J" uniqKey="Hauglund M">M.J. Hauglund</name>
</author>
<author><name sortKey="Tatum, F M" uniqKey="Tatum F">F.M. Tatum</name>
</author>
<author><name sortKey="Bayles, D O" uniqKey="Bayles D">D.O. Bayles</name>
</author>
<author><name sortKey="Maheswaran, S K" uniqKey="Maheswaran S">S.K. Maheswaran</name>
</author>
<author><name sortKey="Briggs, R E" uniqKey="Briggs R">R.E. Briggs</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Klockenbusch, C" uniqKey="Klockenbusch C">C. Klockenbusch</name>
</author>
<author><name sortKey="Kast, J" uniqKey="Kast J">J. Kast</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lainson, F A" uniqKey="Lainson F">F.A. Lainson</name>
</author>
<author><name sortKey="Murray, J" uniqKey="Murray J">J. Murray</name>
</author>
<author><name sortKey="Davies, R C" uniqKey="Davies R">R.C. Davies</name>
</author>
<author><name sortKey="Donachie, W" uniqKey="Donachie W">W. Donachie</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Larsen, J E" uniqKey="Larsen J">J.E. Larsen</name>
</author>
<author><name sortKey="Lund, O" uniqKey="Lund O">O. Lund</name>
</author>
<author><name sortKey="Nielsen, M" uniqKey="Nielsen M">M. Nielsen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lawrence, P K" uniqKey="Lawrence P">P.K. Lawrence</name>
</author>
<author><name sortKey="Kittichotirat, W" uniqKey="Kittichotirat W">W. Kittichotirat</name>
</author>
<author><name sortKey="Bumgarner, R E" uniqKey="Bumgarner R">R.E. Bumgarner</name>
</author>
<author><name sortKey="Mcdermott, J E" uniqKey="Mcdermott J">J.E. McDermott</name>
</author>
<author><name sortKey="Herndon, D R" uniqKey="Herndon D">D.R. Herndon</name>
</author>
<author><name sortKey="Knowles, D P" uniqKey="Knowles D">D.P. Knowles</name>
</author>
<author><name sortKey="Srikumaran, S" uniqKey="Srikumaran S">S. Srikumaran</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lee, R W" uniqKey="Lee R">R.W. Lee</name>
</author>
<author><name sortKey="Strommer, J" uniqKey="Strommer J">J. Strommer</name>
</author>
<author><name sortKey="Hodgins, D" uniqKey="Hodgins D">D. Hodgins</name>
</author>
<author><name sortKey="Shewen, P E" uniqKey="Shewen P">P.E. Shewen</name>
</author>
<author><name sortKey="Niu, Y" uniqKey="Niu Y">Y. Niu</name>
</author>
<author><name sortKey="Lo, R Y" uniqKey="Lo R">R.Y. Lo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lima, A" uniqKey="Lima A">A. Lima</name>
</author>
<author><name sortKey="Duran, R" uniqKey="Duran R">R. Duran</name>
</author>
<author><name sortKey="Schujman, G E" uniqKey="Schujman G">G.E. Schujman</name>
</author>
<author><name sortKey="Marchissio, M J" uniqKey="Marchissio M">M.J. Marchissio</name>
</author>
<author><name sortKey="Portela, M M" uniqKey="Portela M">M.M. Portela</name>
</author>
<author><name sortKey="Obal, G" uniqKey="Obal G">G. Obal</name>
</author>
<author><name sortKey="Pritsch, O" uniqKey="Pritsch O">O. Pritsch</name>
</author>
<author><name sortKey="De Mendoza, D" uniqKey="De Mendoza D">D. de Mendoza</name>
</author>
<author><name sortKey="Cervenansky, C" uniqKey="Cervenansky C">C. Cervenansky</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lo, R Y" uniqKey="Lo R">R.Y. Lo</name>
</author>
<author><name sortKey="Shewen, P E" uniqKey="Shewen P">P.E. Shewen</name>
</author>
<author><name sortKey="Strathdee, C A" uniqKey="Strathdee C">C.A. Strathdee</name>
</author>
<author><name sortKey="Greer, C N" uniqKey="Greer C">C.N. Greer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lo, R Y" uniqKey="Lo R">R.Y. Lo</name>
</author>
<author><name sortKey="Strathdee, C A" uniqKey="Strathdee C">C.A. Strathdee</name>
</author>
<author><name sortKey="Shewen, P E" uniqKey="Shewen P">P.E. Shewen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lo, R Y" uniqKey="Lo R">R.Y. Lo</name>
</author>
<author><name sortKey="Strathdee, C A" uniqKey="Strathdee C">C.A. Strathdee</name>
</author>
<author><name sortKey="Shewen, P E" uniqKey="Shewen P">P.E. Shewen</name>
</author>
<author><name sortKey="Cooney, B J" uniqKey="Cooney B">B.J. Cooney</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mosier, D A" uniqKey="Mosier D">D.A. Mosier</name>
</author>
<author><name sortKey="Simons, K R" uniqKey="Simons K">K.R. Simons</name>
</author>
<author><name sortKey="Confer, A W" uniqKey="Confer A">A.W. Confer</name>
</author>
<author><name sortKey="Panciera, R J" uniqKey="Panciera R">R.J. Panciera</name>
</author>
<author><name sortKey="Clinkenbeard, K D" uniqKey="Clinkenbeard K">K.D. Clinkenbeard</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Narayanan, S K" uniqKey="Narayanan S">S.K. Narayanan</name>
</author>
<author><name sortKey="Nagaraja, T G" uniqKey="Nagaraja T">T.G. Nagaraja</name>
</author>
<author><name sortKey="Chengappa, M M" uniqKey="Chengappa M">M.M. Chengappa</name>
</author>
<author><name sortKey="Stewart, G C" uniqKey="Stewart G">G.C. Stewart</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Orouji, S" uniqKey="Orouji S">S. Orouji</name>
</author>
<author><name sortKey="Hodgins, D C" uniqKey="Hodgins D">D.C. Hodgins</name>
</author>
<author><name sortKey="Lo, R Y" uniqKey="Lo R">R.Y. Lo</name>
</author>
<author><name sortKey="Shewen, P E" uniqKey="Shewen P">P.E. Shewen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Perkins, D N" uniqKey="Perkins D">D.N. Perkins</name>
</author>
<author><name sortKey="Pappin, D J" uniqKey="Pappin D">D.J. Pappin</name>
</author>
<author><name sortKey="Creasy, D M" uniqKey="Creasy D">D.M. Creasy</name>
</author>
<author><name sortKey="Cottrell, J S" uniqKey="Cottrell J">J.S. Cottrell</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Potter, A A" uniqKey="Potter A">A.A. Potter</name>
</author>
<author><name sortKey="Schryvers, A B" uniqKey="Schryvers A">A.B. Schryvers</name>
</author>
<author><name sortKey="Ogunnariwo, J A" uniqKey="Ogunnariwo J">J.A. Ogunnariwo</name>
</author>
<author><name sortKey="Hutchins, W A" uniqKey="Hutchins W">W.A. Hutchins</name>
</author>
<author><name sortKey="Lo, R Y" uniqKey="Lo R">R.Y. Lo</name>
</author>
<author><name sortKey="Watts, T" uniqKey="Watts T">T. Watts</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Potter, T" uniqKey="Potter T">T. Potter</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rabus, R" uniqKey="Rabus R">R. Rabus</name>
</author>
<author><name sortKey="Jack, D L" uniqKey="Jack D">D.L. Jack</name>
</author>
<author><name sortKey="Kelly, D J" uniqKey="Kelly D">D.J. Kelly</name>
</author>
<author><name sortKey="Saier, M H" uniqKey="Saier M">M.H. Saier</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ridpath, J" uniqKey="Ridpath J">J. Ridpath</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rodrigues, M C" uniqKey="Rodrigues M">M.C. Rodrigues</name>
</author>
<author><name sortKey="Cooke, R F" uniqKey="Cooke R">R.F. Cooke</name>
</author>
<author><name sortKey="Marques, R S" uniqKey="Marques R">R.S. Marques</name>
</author>
<author><name sortKey="Cappellozza, B I" uniqKey="Cappellozza B">B.I. Cappellozza</name>
</author>
<author><name sortKey="Arispe, S A" uniqKey="Arispe S">S.A. Arispe</name>
</author>
<author><name sortKey="Keisler, D H" uniqKey="Keisler D">D.H. Keisler</name>
</author>
<author><name sortKey="Bohnert, D W" uniqKey="Bohnert D">D.W. Bohnert</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Roier, S" uniqKey="Roier S">S. Roier</name>
</author>
<author><name sortKey="Fenninger, J C" uniqKey="Fenninger J">J.C. Fenninger</name>
</author>
<author><name sortKey="Leitner, D R" uniqKey="Leitner D">D.R. Leitner</name>
</author>
<author><name sortKey="Rechberger, G N" uniqKey="Rechberger G">G.N. Rechberger</name>
</author>
<author><name sortKey="Reidl, J" uniqKey="Reidl J">J. Reidl</name>
</author>
<author><name sortKey="Schild, S" uniqKey="Schild S">S. Schild</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Shewen, P E" uniqKey="Shewen P">P.E. Shewen</name>
</author>
<author><name sortKey="Wilkie, B N" uniqKey="Wilkie B">B.N. Wilkie</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Shewen, P E" uniqKey="Shewen P">P.E. Shewen</name>
</author>
<author><name sortKey="Wilkie, B N" uniqKey="Wilkie B">B.N. Wilkie</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Singh, K" uniqKey="Singh K">K. Singh</name>
</author>
<author><name sortKey="Ritchey, J W" uniqKey="Ritchey J">J.W. Ritchey</name>
</author>
<author><name sortKey="Confer, A W" uniqKey="Confer A">A.W. Confer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Studier, F W" uniqKey="Studier F">F.W. Studier</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Vougidou, C" uniqKey="Vougidou C">C. Vougidou</name>
</author>
<author><name sortKey="Sandalakis, V" uniqKey="Sandalakis V">V. Sandalakis</name>
</author>
<author><name sortKey="Psaroulaki, A" uniqKey="Psaroulaki A">A. Psaroulaki</name>
</author>
<author><name sortKey="Petridou, E" uniqKey="Petridou E">E. Petridou</name>
</author>
<author><name sortKey="Ekateriniadou, L" uniqKey="Ekateriniadou L">L. Ekateriniadou</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Youssef, S A" uniqKey="Youssef S">S.A. Youssef</name>
</author>
<author><name sortKey="Clark, M E" uniqKey="Clark M">M.E. Clark</name>
</author>
<author><name sortKey="Caswell, J L" uniqKey="Caswell J">J.L. Caswell</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zecchinon, L" uniqKey="Zecchinon L">L. Zecchinon</name>
</author>
<author><name sortKey="Fett, T" uniqKey="Fett T">T. Fett</name>
</author>
<author><name sortKey="Desmecht, D" uniqKey="Desmecht D">D. Desmecht</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV2/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000643 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 000643 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= CovidV2 |flux= Ncbi |étape= Curation |type= RBID |clé= PMC:5035357 |texte= Identification of Leukotoxin and other vaccine candidate proteins in a Mannheimia haemolytica commercial antigen }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:27699279" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \ | NlmPubMed2Wicri -a CovidV2
This area was generated with Dilib version V0.6.33. |