Relationship between the GOLD combined COPD assessment staging system and bacterial isolation
Identifieur interne : 000465 ( Ncbi/Curation ); précédent : 000464; suivant : 000466Relationship between the GOLD combined COPD assessment staging system and bacterial isolation
Auteurs : Yusuf Aydemir [Turquie] ; Özlem Aydemir [Turquie] ; Fatma Kalem [Turquie]Source :
- International Journal of Chronic Obstructive Pulmonary Disease [ 1176-9106 ] ; 2014.
Abstract
Acute exacerbations, which are a significant cause of mortality and morbidity, adversely affect chronic obstructive pulmonary disease (COPD) prognosis by accelerating loss of lung function. It is important to know the microorganisms that commonly cause exacerbations in the patient groups classified according to clinical and functional characteristics for fast and accurate treatment of acute exacerbations.
The last Global Initiative for Chronic Obstructive Lung Disease (GOLD) publication recommended a new staging system containing obstruction degree, frequency of exacerbations, and quality of life questionnaires. This study is designed to analyze the relationship between the bacteria isolated in acute exacerbations and new GOLD stages.
Potentially pathogenic bacteria (PPB) isolation with culture and polymerase chain reaction methods were obtained from 114 acute exacerbation COPD patients, classified into A, B, C, and D groups by analyzing the forced expiratory volume in 1 second (FEV1) value, COPD Assessment Test (CAT) score, and exacerbation frequency according to the new GOLD staging system.
There was a significant correlation between exacerbation frequency and PPB isolation (
Bacterial infection may cause an acute exacerbation equally in each stage for COPD. The difference in bacterial etiology is more related to exacerbation frequency than FEV1 and CAT scores for an acute exacerbation. Determining exacerbation frequency is significant for treatment success in empirical antibiotic selection.
Url:
DOI: 10.2147/COPD.S70620
PubMed: 25298733
PubMed Central: 4186572
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000889
- to stream Pmc, to step Curation: Pour aller vers cette notice dans l'étape Curation :000889
- to stream Pmc, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000619
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :000465
Links to Exploration step
PMC:4186572Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Relationship between the GOLD combined COPD assessment staging system and bacterial isolation</title>
<author><name sortKey="Aydemir, Yusuf" sort="Aydemir, Yusuf" uniqKey="Aydemir Y" first="Yusuf" last="Aydemir">Yusuf Aydemir</name>
<affiliation wicri:level="1"><nlm:aff id="af1-copd-9-1045">Department of Respiratory Medicine, Sakarya University, Sakarya, Turkey</nlm:aff>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Department of Respiratory Medicine, Sakarya University, Sakarya</wicri:regionArea>
<wicri:noRegion>Sakarya</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Aydemir, Ozlem" sort="Aydemir, Ozlem" uniqKey="Aydemir O" first="Özlem" last="Aydemir">Özlem Aydemir</name>
<affiliation wicri:level="1"><nlm:aff id="af2-copd-9-1045">Department of Microbiology, Sakarya University, Sakarya, Turkey</nlm:aff>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Department of Microbiology, Sakarya University, Sakarya</wicri:regionArea>
<wicri:noRegion>Sakarya</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kalem, Fatma" sort="Kalem, Fatma" uniqKey="Kalem F" first="Fatma" last="Kalem">Fatma Kalem</name>
<affiliation wicri:level="1"><nlm:aff id="af3-copd-9-1045">Department of Microbiology, Konya Numune Hospital, Konya, Turkey</nlm:aff>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Department of Microbiology, Konya Numune Hospital, Konya</wicri:regionArea>
<wicri:noRegion>Konya</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">25298733</idno>
<idno type="pmc">4186572</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186572</idno>
<idno type="RBID">PMC:4186572</idno>
<idno type="doi">10.2147/COPD.S70620</idno>
<date when="2014">2014</date>
<idno type="wicri:Area/Pmc/Corpus">000889</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000889</idno>
<idno type="wicri:Area/Pmc/Curation">000889</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000889</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000619</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000619</idno>
<idno type="wicri:Area/Ncbi/Merge">000465</idno>
<idno type="wicri:Area/Ncbi/Curation">000465</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Relationship between the GOLD combined COPD assessment staging system and bacterial isolation</title>
<author><name sortKey="Aydemir, Yusuf" sort="Aydemir, Yusuf" uniqKey="Aydemir Y" first="Yusuf" last="Aydemir">Yusuf Aydemir</name>
<affiliation wicri:level="1"><nlm:aff id="af1-copd-9-1045">Department of Respiratory Medicine, Sakarya University, Sakarya, Turkey</nlm:aff>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Department of Respiratory Medicine, Sakarya University, Sakarya</wicri:regionArea>
<wicri:noRegion>Sakarya</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Aydemir, Ozlem" sort="Aydemir, Ozlem" uniqKey="Aydemir O" first="Özlem" last="Aydemir">Özlem Aydemir</name>
<affiliation wicri:level="1"><nlm:aff id="af2-copd-9-1045">Department of Microbiology, Sakarya University, Sakarya, Turkey</nlm:aff>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Department of Microbiology, Sakarya University, Sakarya</wicri:regionArea>
<wicri:noRegion>Sakarya</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kalem, Fatma" sort="Kalem, Fatma" uniqKey="Kalem F" first="Fatma" last="Kalem">Fatma Kalem</name>
<affiliation wicri:level="1"><nlm:aff id="af3-copd-9-1045">Department of Microbiology, Konya Numune Hospital, Konya, Turkey</nlm:aff>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Department of Microbiology, Konya Numune Hospital, Konya</wicri:regionArea>
<wicri:noRegion>Konya</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">International Journal of Chronic Obstructive Pulmonary Disease</title>
<idno type="ISSN">1176-9106</idno>
<idno type="eISSN">1178-2005</idno>
<imprint><date when="2014">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p>Acute exacerbations, which are a significant cause of mortality and morbidity, adversely affect chronic obstructive pulmonary disease (COPD) prognosis by accelerating loss of lung function. It is important to know the microorganisms that commonly cause exacerbations in the patient groups classified according to clinical and functional characteristics for fast and accurate treatment of acute exacerbations.</p>
</sec>
<sec><title>Objectives</title>
<p>The last Global Initiative for Chronic Obstructive Lung Disease (GOLD) publication recommended a new staging system containing obstruction degree, frequency of exacerbations, and quality of life questionnaires. This study is designed to analyze the relationship between the bacteria isolated in acute exacerbations and new GOLD stages.</p>
</sec>
<sec><title>Methods</title>
<p>Potentially pathogenic bacteria (PPB) isolation with culture and polymerase chain reaction methods were obtained from 114 acute exacerbation COPD patients, classified into A, B, C, and D groups by analyzing the forced expiratory volume in 1 second (FEV<sub>1</sub>
) value, COPD Assessment Test (CAT) score, and exacerbation frequency according to the new GOLD staging system.</p>
</sec>
<sec><title>Results</title>
<p>There was a significant correlation between exacerbation frequency and PPB isolation (<italic>P</italic>
=0.002). There was no relationship between GOLD stage, FEV<sub>1</sub>
, and CAT score with PPB isolation. The isolated bacteria diversity and mixed infection frequency were higher in the GOLD stage D group. <italic>Pseudomonas aeruginosa, Escherichia coli</italic>
, and <italic>Acinetobacter baumannii</italic>
were isolated only from D group patients.</p>
</sec>
<sec><title>Conclusion</title>
<p>Bacterial infection may cause an acute exacerbation equally in each stage for COPD. The difference in bacterial etiology is more related to exacerbation frequency than FEV<sub>1</sub>
and CAT scores for an acute exacerbation. Determining exacerbation frequency is significant for treatment success in empirical antibiotic selection.</p>
</sec>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Seemungal, Ta" uniqKey="Seemungal T">TA Seemungal</name>
</author>
<author><name sortKey="Donaldson, Gc" uniqKey="Donaldson G">GC Donaldson</name>
</author>
<author><name sortKey="Paul, Ea" uniqKey="Paul E">EA Paul</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hurst, Jr" uniqKey="Hurst J">JR Hurst</name>
</author>
<author><name sortKey="Vestbo, J" uniqKey="Vestbo J">J Vestbo</name>
</author>
<author><name sortKey="Anzueto, A" uniqKey="Anzueto A">A Anzueto</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Celli, Br" uniqKey="Celli B">BR Celli</name>
</author>
<author><name sortKey="Thomas, Ne" uniqKey="Thomas N">NE Thomas</name>
</author>
<author><name sortKey="Anderson, Ja" uniqKey="Anderson J">JA Anderson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zhang, M" uniqKey="Zhang M">M Zhang</name>
</author>
<author><name sortKey="Li, Q" uniqKey="Li Q">Q Li</name>
</author>
<author><name sortKey="Zhang, Xy" uniqKey="Zhang X">XY Zhang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sethi, S" uniqKey="Sethi S">S Sethi</name>
</author>
<author><name sortKey="Murphy, Tf" uniqKey="Murphy T">TF Murphy</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Yusen, Rd" uniqKey="Yusen R">RD Yusen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Eller, J" uniqKey="Eller J">J Eller</name>
</author>
<author><name sortKey="Ede, A" uniqKey="Ede A">A Ede</name>
</author>
<author><name sortKey="Schaberg, T" uniqKey="Schaberg T">T Schaberg</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Miravitlles, M" uniqKey="Miravitlles M">M Miravitlles</name>
</author>
<author><name sortKey="Espinosa, C" uniqKey="Espinosa C">C Espinosa</name>
</author>
<author><name sortKey="Fernandez Laso, E" uniqKey="Fernandez Laso E">E Fernández-Laso</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Soler, N" uniqKey="Soler N">N Soler</name>
</author>
<author><name sortKey="Agusti, C" uniqKey="Agusti C">C Agustí</name>
</author>
<author><name sortKey="Angrill, J" uniqKey="Angrill J">J Angrill</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Anthonisen, Nr" uniqKey="Anthonisen N">NR Anthonisen</name>
</author>
<author><name sortKey="Manfreda, J" uniqKey="Manfreda J">J Manfreda</name>
</author>
<author><name sortKey="Warren, Cp" uniqKey="Warren C">CP Warren</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Stockley, Ra" uniqKey="Stockley R">RA Stockley</name>
</author>
<author><name sortKey="O Rien, C" uniqKey="O Rien C">C O’Brien</name>
</author>
<author><name sortKey="Pye, A" uniqKey="Pye A">A Pye</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Miravittles, M" uniqKey="Miravittles M">M Miravittles</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wedzicha, Ja" uniqKey="Wedzicha J">JA Wedzicha</name>
</author>
<author><name sortKey="Donaldson, Gc" uniqKey="Donaldson G">GC Donaldson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Li, Xj" uniqKey="Li X">XJ Li</name>
</author>
<author><name sortKey="Li, Q" uniqKey="Li Q">Q Li</name>
</author>
<author><name sortKey="Si, Ly" uniqKey="Si L">LY Si</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Roche, N" uniqKey="Roche N">N Roche</name>
</author>
<author><name sortKey="Kouassi, B" uniqKey="Kouassi B">B Kouassi</name>
</author>
<author><name sortKey="Rabbat, A" uniqKey="Rabbat A">A Rabbat</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Huang, Yj" uniqKey="Huang Y">YJ Huang</name>
</author>
<author><name sortKey="Lynch, Sv" uniqKey="Lynch S">SV Lynch</name>
</author>
<author><name sortKey="Wiener Kronish, Jp" uniqKey="Wiener Kronish J">JP Wiener-Kronish</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Curran, T" uniqKey="Curran T">T Curran</name>
</author>
<author><name sortKey="Coyle, Pv" uniqKey="Coyle P">PV Coyle</name>
</author>
<author><name sortKey="Mcmanus, Te" uniqKey="Mcmanus T">TE McManus</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Morozumi, M" uniqKey="Morozumi M">M Morozumi</name>
</author>
<author><name sortKey="Nakayama, E" uniqKey="Nakayama E">E Nakayama</name>
</author>
<author><name sortKey="Iwata, S" uniqKey="Iwata S">S Iwata</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Str Lin, K" uniqKey="Str Lin K">K Strålin</name>
</author>
<author><name sortKey="Korsgaard, J" uniqKey="Korsgaard J">J Korsgaard</name>
</author>
<author><name sortKey="Olcen, P" uniqKey="Olcen P">P Olcén</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Brumf Tt, W" uniqKey="Brumf Tt W">W Brumfıtt</name>
</author>
<author><name sortKey="W Lloughby, Ml" uniqKey="W Lloughby M">Ml Wılloughby</name>
</author>
<author><name sortKey="Bromley, Ll" uniqKey="Bromley L">LL Bromley</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Cabello, H" uniqKey="Cabello H">H Cabello</name>
</author>
<author><name sortKey="Torres, A" uniqKey="Torres A">A Torres</name>
</author>
<author><name sortKey="Celis, R" uniqKey="Celis R">R Celis</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rosell, A" uniqKey="Rosell A">A Rosell</name>
</author>
<author><name sortKey="Mons, E" uniqKey="Mons E">E Monsó</name>
</author>
<author><name sortKey="Soler, N" uniqKey="Soler N">N Soler</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Garcha, Ds" uniqKey="Garcha D">DS Garcha</name>
</author>
<author><name sortKey="Thurston, Sj" uniqKey="Thurston S">SJ Thurston</name>
</author>
<author><name sortKey="Patel, Ar" uniqKey="Patel A">AR Patel</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Veeramachaneni, Sb" uniqKey="Veeramachaneni S">SB Veeramachaneni</name>
</author>
<author><name sortKey="Sethi, S" uniqKey="Sethi S">S Sethi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Patel, Is" uniqKey="Patel I">IS Patel</name>
</author>
<author><name sortKey="Seemungal, Ta" uniqKey="Seemungal T">TA Seemungal</name>
</author>
<author><name sortKey="Wilks, M" uniqKey="Wilks M">M Wilks</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sethi, S" uniqKey="Sethi S">S Sethi</name>
</author>
<author><name sortKey="Evans, N" uniqKey="Evans N">N Evans</name>
</author>
<author><name sortKey="Grant, Bj" uniqKey="Grant B">BJ Grant</name>
</author>
<author><name sortKey="Murphy, Tf" uniqKey="Murphy T">TF Murphy</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Perotin, Jm" uniqKey="Perotin J">JM Perotin</name>
</author>
<author><name sortKey="Dury, S" uniqKey="Dury S">S Dury</name>
</author>
<author><name sortKey="Renois, F" uniqKey="Renois F">F Renois</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV2/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000465 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 000465 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= CovidV2 |flux= Ncbi |étape= Curation |type= RBID |clé= PMC:4186572 |texte= Relationship between the GOLD combined COPD assessment staging system and bacterial isolation }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:25298733" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \ | NlmPubMed2Wicri -a CovidV2
![]() | This area was generated with Dilib version V0.6.33. | ![]() |