Profiling Early Humoral Response to Diagnose Novel Coronavirus Disease (COVID-19).
Identifieur interne : 000447 ( Main/Exploration ); précédent : 000446; suivant : 000448Profiling Early Humoral Response to Diagnose Novel Coronavirus Disease (COVID-19).
Auteurs : Li Guo [République populaire de Chine] ; Lili Ren [République populaire de Chine] ; Siyuan Yang [République populaire de Chine] ; Meng Xiao [République populaire de Chine] ; De Chang [République populaire de Chine] ; Fan Yang ; Charles S. Dela Cruz [États-Unis] ; Yingying Wang [République populaire de Chine] ; Chao Wu [République populaire de Chine] ; Yan Xiao [République populaire de Chine] ; Lulu Zhang [République populaire de Chine] ; Lianlian Han [République populaire de Chine] ; Shengyuan Dang [République populaire de Chine] ; Yan Xu [République populaire de Chine] ; Qiwen Yang [République populaire de Chine] ; Shengyong Xu [République populaire de Chine] ; Huadong Zhu [République populaire de Chine] ; Yingchun Xu [République populaire de Chine] ; Qi Jin ; Lokesh Sharma [États-Unis] ; Linghang Wang [République populaire de Chine] ; Jianwei Wang [République populaire de Chine]Source :
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [ 1537-6591 ] ; 2020.
Abstract
Emergence of coronavirus disease 2019 (COVID-19) is a major healthcare threat. Current method of detection involves qPCR-based technique, which identifies the viral nucleic acids when present in sufficient quantity. False negative results can be achieved and failure to quarantine the infected patient would be a major setback in containing the viral transmission. We here aim to describe the time kinetics of various antibodies produced against the 2019 novel coronavirus (SARS-CoV-2) and evaluate the potential of antibody testing to diagnose COVID-19.
DOI: 10.1093/cid/ciaa310
PubMed: 32198501
Affiliations:
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</author>
<author><name sortKey="Wu, Chao" sort="Wu, Chao" uniqKey="Wu C" first="Chao" last="Wu">Chao Wu</name>
<affiliation wicri:level="3"><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Xiao, Yan" sort="Xiao, Yan" uniqKey="Xiao Y" first="Yan" last="Xiao">Yan Xiao</name>
<affiliation wicri:level="3"><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Zhang, Lulu" sort="Zhang, Lulu" uniqKey="Zhang L" first="Lulu" last="Zhang">Lulu Zhang</name>
<affiliation wicri:level="3"><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Han, Lianlian" sort="Han, Lianlian" uniqKey="Han L" first="Lianlian" last="Han">Lianlian Han</name>
<affiliation wicri:level="3"><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Dang, Shengyuan" sort="Dang, Shengyuan" uniqKey="Dang S" first="Shengyuan" last="Dang">Shengyuan Dang</name>
<affiliation wicri:level="3"><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Xu, Yan" sort="Xu, Yan" uniqKey="Xu Y" first="Yan" last="Xu">Yan Xu</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Respiratory and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>Department of Respiratory and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Yang, Qiwen" sort="Yang, Qiwen" uniqKey="Yang Q" first="Qiwen" last="Yang">Qiwen Yang</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Laboratory Medicine & Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>Department of Laboratory Medicine & Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Xu, Shengyong" sort="Xu, Shengyong" uniqKey="Xu S" first="Shengyong" last="Xu">Shengyong Xu</name>
<affiliation wicri:level="3"><nlm:affiliation>Emergency Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>Emergency Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Zhu, Huadong" sort="Zhu, Huadong" uniqKey="Zhu H" first="Huadong" last="Zhu">Huadong Zhu</name>
<affiliation wicri:level="3"><nlm:affiliation>Emergency Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>Emergency Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Xu, Yingchun" sort="Xu, Yingchun" uniqKey="Xu Y" first="Yingchun" last="Xu">Yingchun Xu</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Laboratory Medicine & Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>Department of Laboratory Medicine & Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Jin, Qi" sort="Jin, Qi" uniqKey="Jin Q" first="Qi" last="Jin">Qi Jin</name>
<affiliation><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing P. R. China.</nlm:affiliation>
<wicri:noCountry code="subField">Beijing P</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Sharma, Lokesh" sort="Sharma, Lokesh" uniqKey="Sharma L" first="Lokesh" last="Sharma">Lokesh Sharma</name>
<affiliation wicri:level="2"><nlm:affiliation>Section of Pulmonary and Critical Care and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, CT USA.</nlm:affiliation>
<country>États-Unis</country>
<placeName><region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Section of Pulmonary and Critical Care and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Wang, Linghang" sort="Wang, Linghang" uniqKey="Wang L" first="Linghang" last="Wang">Linghang Wang</name>
<affiliation wicri:level="3"><nlm:affiliation>Emergency Department of Infectious Diseases of Beijing Ditan Hospital, Capital Medical University, Beijing, P. R. China.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>Emergency Department of Infectious Diseases of Beijing Ditan Hospital, Capital Medical University, Beijing</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wang, Jianwei" sort="Wang, Jianwei" uniqKey="Wang J" first="Jianwei" last="Wang">Jianwei Wang</name>
<affiliation wicri:level="3"><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country>
<wicri:regionArea>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Clinical infectious diseases : an official publication of the Infectious Diseases Society of America</title>
<idno type="eISSN">1537-6591</idno>
<imprint><date when="2020" type="published">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Emergence of coronavirus disease 2019 (COVID-19) is a major healthcare threat. Current method of detection involves qPCR-based technique, which identifies the viral nucleic acids when present in sufficient quantity. False negative results can be achieved and failure to quarantine the infected patient would be a major setback in containing the viral transmission. We here aim to describe the time kinetics of various antibodies produced against the 2019 novel coronavirus (SARS-CoV-2) and evaluate the potential of antibody testing to diagnose COVID-19.</div>
</front>
</TEI>
<affiliations><list><country><li>République populaire de Chine</li>
<li>États-Unis</li>
</country>
<region><li>Connecticut</li>
</region>
<settlement><li>Pékin</li>
</settlement>
</list>
<tree><noCountry><name sortKey="Jin, Qi" sort="Jin, Qi" uniqKey="Jin Q" first="Qi" last="Jin">Qi Jin</name>
<name sortKey="Yang, Fan" sort="Yang, Fan" uniqKey="Yang F" first="Fan" last="Yang">Fan Yang</name>
</noCountry>
<country name="République populaire de Chine"><noRegion><name sortKey="Guo, Li" sort="Guo, Li" uniqKey="Guo L" first="Li" last="Guo">Li Guo</name>
</noRegion>
<name sortKey="Chang, De" sort="Chang, De" uniqKey="Chang D" first="De" last="Chang">De Chang</name>
<name sortKey="Dang, Shengyuan" sort="Dang, Shengyuan" uniqKey="Dang S" first="Shengyuan" last="Dang">Shengyuan Dang</name>
<name sortKey="Han, Lianlian" sort="Han, Lianlian" uniqKey="Han L" first="Lianlian" last="Han">Lianlian Han</name>
<name sortKey="Ren, Lili" sort="Ren, Lili" uniqKey="Ren L" first="Lili" last="Ren">Lili Ren</name>
<name sortKey="Wang, Jianwei" sort="Wang, Jianwei" uniqKey="Wang J" first="Jianwei" last="Wang">Jianwei Wang</name>
<name sortKey="Wang, Linghang" sort="Wang, Linghang" uniqKey="Wang L" first="Linghang" last="Wang">Linghang Wang</name>
<name sortKey="Wang, Yingying" sort="Wang, Yingying" uniqKey="Wang Y" first="Yingying" last="Wang">Yingying Wang</name>
<name sortKey="Wu, Chao" sort="Wu, Chao" uniqKey="Wu C" first="Chao" last="Wu">Chao Wu</name>
<name sortKey="Xiao, Meng" sort="Xiao, Meng" uniqKey="Xiao M" first="Meng" last="Xiao">Meng Xiao</name>
<name sortKey="Xiao, Yan" sort="Xiao, Yan" uniqKey="Xiao Y" first="Yan" last="Xiao">Yan Xiao</name>
<name sortKey="Xu, Shengyong" sort="Xu, Shengyong" uniqKey="Xu S" first="Shengyong" last="Xu">Shengyong Xu</name>
<name sortKey="Xu, Yan" sort="Xu, Yan" uniqKey="Xu Y" first="Yan" last="Xu">Yan Xu</name>
<name sortKey="Xu, Yingchun" sort="Xu, Yingchun" uniqKey="Xu Y" first="Yingchun" last="Xu">Yingchun Xu</name>
<name sortKey="Yang, Qiwen" sort="Yang, Qiwen" uniqKey="Yang Q" first="Qiwen" last="Yang">Qiwen Yang</name>
<name sortKey="Yang, Siyuan" sort="Yang, Siyuan" uniqKey="Yang S" first="Siyuan" last="Yang">Siyuan Yang</name>
<name sortKey="Zhang, Lulu" sort="Zhang, Lulu" uniqKey="Zhang L" first="Lulu" last="Zhang">Lulu Zhang</name>
<name sortKey="Zhu, Huadong" sort="Zhu, Huadong" uniqKey="Zhu H" first="Huadong" last="Zhu">Huadong Zhu</name>
</country>
<country name="États-Unis"><region name="Connecticut"><name sortKey="Dela Cruz, Charles S" sort="Dela Cruz, Charles S" uniqKey="Dela Cruz C" first="Charles S" last="Dela Cruz">Charles S. Dela Cruz</name>
</region>
<name sortKey="Sharma, Lokesh" sort="Sharma, Lokesh" uniqKey="Sharma L" first="Lokesh" last="Sharma">Lokesh Sharma</name>
</country>
</tree>
</affiliations>
</record>
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