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Abstracts Thirty‐Seventh Annual Meeting American College of Clinical Pharmacology September 14–16, 2008 Philadelphia, Pennsylvania

Identifieur interne : 000E72 ( Main/Exploration ); précédent : 000E71; suivant : 000E73

Abstracts Thirty‐Seventh Annual Meeting American College of Clinical Pharmacology September 14–16, 2008 Philadelphia, Pennsylvania

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RBID : ISTEX:FEFFD0E0EA5DD8BC354E95FB067B58926CA15244

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DOI: 10.1177/00912700080480091001


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<title level="j" type="main">The Journal of Clinical Pharmacology</title>
<title level="j" type="alt">JOURNAL OF CLINICAL PHARMACOLOGY</title>
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<term>Admission units</term>
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<term>Anal ysis</term>
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<term>Apix aban</term>
<term>Apixaban</term>
<term>Apixaban phase</term>
<term>Apixaban plasma concentration</term>
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<term>Apparent clearance</term>
<term>Apparent volume</term>
<term>Approxima tely</term>
<term>Armoda finil</term>
<term>Aromatic alkaloids</term>
<term>Assay</term>
<term>Asse ssed</term>
<term>Asthma patients</term>
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<term>Base line</term>
<term>Baseline</term>
<term>Baseline disease activity</term>
<term>Baseline hepatic</term>
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<term>Bhuvana jayararnan</term>
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<term>Bioavailability</term>
<term>Biomarker</term>
<term>Biomarkers</term>
<term>Bjects</term>
<term>Blood pressure</term>
<term>Blood samp</term>
<term>Blood sample</term>
<term>Blood samples</term>
<term>Body weig</term>
<term>Body weight</term>
<term>Bolus dose</term>
<term>Caffeine</term>
<term>Caffeine concentration</term>
<term>Caffeine concentrations</term>
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<term>Carbonated sodas</term>
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<term>Chil dren</term>
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<term>Conclus</term>
<term>Conclus ions</term>
<term>Concomitant</term>
<term>Concomitant medications</term>
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<term>Confidence interval</term>
<term>Confidence intervals</term>
<term>Cons ists</term>
<term>Contro</term>
<term>Coso lvents</term>
<term>Covariate</term>
<term>Covariates</term>
<term>Creatinine</term>
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<term>Crossover design</term>
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<term>Daiichi sankyo</term>
<term>Daily dose</term>
<term>Dapa gliflozin</term>
<term>Data base</term>
<term>Data types</term>
<term>Database</term>
<term>Demographic characteristics</term>
<term>Depression disease</term>
<term>Design synthesis</term>
<term>Determ ined</term>
<term>Deve</term>
<term>Develo pment</term>
<term>Developmental changes</term>
<term>Diabetes mellitus</term>
<term>Differe</term>
<term>Dimple patel</term>
<term>Direct factor</term>
<term>Discovery medicine</term>
<term>Distribu tion</term>
<term>Dos</term>
<term>Dose</term>
<term>Dose administration</term>
<term>Dose level</term>
<term>Dose range</term>
<term>Dose regimen</term>
<term>Dose selection</term>
<term>Dose studies</term>
<term>Dose study</term>
<term>Dosing</term>
<term>Dosing regimen</term>
<term>Dosing requirements</term>
<term>Drug administration</term>
<term>Drug safety</term>
<term>Drug therapy</term>
<term>Drug utilization</term>
<term>Ect</term>
<term>Effec</term>
<term>Effect model</term>
<term>Efficacy outcomes</term>
<term>Emax models</term>
<term>Endo morphin</term>
<term>Enfennedades respiratorias</term>
<term>Ents</term>
<term>Erythrocyte sedimentation rate</term>
<term>Estab lished</term>
<term>Estima</term>
<term>Ethods</term>
<term>Etoricoxib</term>
<term>Excretion</term>
<term>Expo</term>
<term>Expos ures</term>
<term>Exposure model</term>
<term>Extension trial</term>
<term>Ferulic acid</term>
<term>Ffects modeling</term>
<term>Fibrinogen</term>
<term>Final model</term>
<term>Final population</term>
<term>Finil</term>
<term>First order absorption</term>
<term>First time</term>
<term>First year</term>
<term>Foll</term>
<term>Forecasting algorithm</term>
<term>Future studies</term>
<term>Gaba pentin</term>
<term>Gabape ntin</term>
<term>Gabapentin</term>
<term>Gabapentin exposu</term>
<term>Gabapentin exposure</term>
<term>Gender</term>
<term>Gender differences</term>
<term>Gender distribution</term>
<term>Geome tric</term>
<term>Glom eruli</term>
<term>Good source</term>
<term>Great valley parkway</term>
<term>Grou</term>
<term>Hartmut derendorf</term>
<term>Healthy adult smokers</term>
<term>Healthy adults</term>
<term>Healthy population</term>
<term>Healthy subj ects</term>
<term>Healthy subjects</term>
<term>Healthy volunteers</term>
<term>Heart rate</term>
<term>Hosp ital</term>
<term>Hospital admission</term>
<term>Hplc method</term>
<term>Huma</term>
<term>Iatric</term>
<term>Iatric patient</term>
<term>Ical</term>
<term>Icine</term>
<term>Ients</term>
<term>Ification drop</term>
<term>Ility</term>
<term>Important role</term>
<term>Incl</term>
<term>Incl uded</term>
<term>Ined</term>
<term>Inflamm ation</term>
<term>Informatics system</term>
<term>Infusion</term>
<term>Inhi bitor</term>
<term>Inhibitor</term>
<term>Instituto nacional</term>
<term>Inte</term>
<term>Intercompartmental clearance</term>
<term>Interethnic differences</term>
<term>Intestinal tract</term>
<term>Inves tigated</term>
<term>Invo lved</term>
<term>Ived</term>
<term>Ized</term>
<term>Jeffrey</term>
<term>Kine tics</term>
<term>Knopp neurosciences</term>
<term>Lation</term>
<term>Least squares</term>
<term>Lebo witz</term>
<term>Lerab ility</term>
<term>Leve</term>
<term>Ling</term>
<term>Linical pharmacology</term>
<term>Logistic regression</term>
<term>Logy</term>
<term>Lonnie rimmer</term>
<term>Lowe</term>
<term>Lower concentration</term>
<term>Lthy</term>
<term>Luated</term>
<term>Lysis</term>
<term>Mahesh narayan</term>
<term>Marc pfister</term>
<term>Mass balance</term>
<term>Mayo</term>
<term>Mayo clinic</term>
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<term>Median</term>
<term>Medical need</term>
<term>Medication</term>
<term>Medicine rochester</term>
<term>Meeting abstracts</term>
<term>Meloxicam</term>
<term>Ment</term>
<term>Merck</term>
<term>Merck research laboratories</term>
<term>Metab olism</term>
<term>Metabo</term>
<term>Metabolism</term>
<term>Meth</term>
<term>Mexico city</term>
<term>Mglkg</term>
<term>Mild dizziness</term>
<term>Mina tion</term>
<term>Ministra tion</term>
<term>Moda finil</term>
<term>Mode ling</term>
<term>Modeling</term>
<term>Mountain view</term>
<term>Mouse model</term>
<term>Mpared</term>
<term>Msec</term>
<term>Multiple doses</term>
<term>Naproxen</term>
<term>National institute</term>
<term>Natriuretic</term>
<term>Nclus ions</term>
<term>Neon ates</term>
<term>Nitive functions</term>
<term>Noncompartmental methods</term>
<term>Nonmem</term>
<term>Normal doses</term>
<term>Nove</term>
<term>Novel diagnostics</term>
<term>Novel peptide</term>
<term>Ntly</term>
<term>Ntra</term>
<term>Ntra tions</term>
<term>Obatoclax</term>
<term>Obese</term>
<term>Obese patients</term>
<term>Obse</term>
<term>Observational study</term>
<term>Obta ined</term>
<term>Oncology</term>
<term>Open heart surgery</term>
<term>Openlabel study</term>
<term>Oral contraceptives</term>
<term>Oral corticosteroids</term>
<term>Oral doses</term>
<term>Oral dosing</term>
<term>Oral pharmacokinetics</term>
<term>Other populations</term>
<term>Oxidative stress</term>
<term>Para</term>
<term>Para meters</term>
<term>Parame ters</term>
<term>Parameter</term>
<term>Pathway</term>
<term>Pati</term>
<term>Pati ents</term>
<term>Patie</term>
<term>Patien</term>
<term>Pediatric</term>
<term>Pediatric health care professionals</term>
<term>Pediatric patients</term>
<term>Pennsylvania school</term>
<term>Peptide</term>
<term>Peripheral volume</term>
<term>Pharm</term>
<term>Pharma</term>
<term>Pharma cokinetics</term>
<term>Pharma cology</term>
<term>Pharmaceutical</term>
<term>Pharmaco</term>
<term>Pharmaco kinetics</term>
<term>Pharmacokine tics</term>
<term>Pharmacokinetic</term>
<term>Pharmacokinetic parameters</term>
<term>Pharmacokinetics</term>
<term>Pharmacol</term>
<term>Pharmacology</term>
<term>Pharmacotherapy</term>
<term>Pharmacotherapy guidance</term>
<term>Pkjpd</term>
<term>Pkjpd modeling</term>
<term>Pklpd</term>
<term>Pklpd simulation</term>
<term>Placebo</term>
<term>Placebo infusion</term>
<term>Placebo patch</term>
<term>Plasma</term>
<term>Plasma concentration</term>
<term>Plasma concentrations</term>
<term>Plasma levels</term>
<term>Plasma samples</term>
<term>Popu</term>
<term>Popu lation</term>
<term>Popula tion</term>
<term>Population pharma cokinetics</term>
<term>Positive control</term>
<term>Possible covariates</term>
<term>Potential biomarkers</term>
<term>Pred</term>
<term>Predictive tool</term>
<term>Prednisolone tablet</term>
<term>Present study</term>
<term>Probe drug</term>
<term>Pulse wave velocity</term>
<term>Query</term>
<term>Random ized</term>
<term>Randomized</term>
<term>Rece</term>
<term>Rece ived</term>
<term>Recep</term>
<term>Receptor</term>
<term>Receptor antagonist</term>
<term>Receptor occupancy</term>
<term>Records system</term>
<term>Regimen</term>
<term>Rela tionship</term>
<term>Renal</term>
<term>Renal clearance</term>
<term>Renal funct</term>
<term>Renal functions</term>
<term>Renin</term>
<term>Repo rting</term>
<term>Research center</term>
<term>Residual</term>
<term>Residual variability</term>
<term>Respe ctively</term>
<term>Respec tively</term>
<term>Response rate</term>
<term>Resu</term>
<term>Resul</term>
<term>Rheumatoid arthritis</term>
<term>Ribavirin</term>
<term>Risk factors</term>
<term>Ritonavir</term>
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<term>Rivo tablets</term>
<term>Robin blumenthal</term>
<term>Robust predictions</term>
<term>Same doses</term>
<term>Sample size</term>
<term>Sampling design</term>
<term>Sankyo</term>
<term>Santa clara</term>
<term>Scenario</term>
<term>Secondary prevention</term>
<term>Seminal vesicle</term>
<term>Sequential</term>
<term>Sequential groups</term>
<term>Sick children</term>
<term>Side effects</term>
<term>Sign ifica</term>
<term>Signi</term>
<term>Signi fica ntly</term>
<term>Signi ficantly</term>
<term>Signific antly</term>
<term>Significan</term>
<term>Significant covariate</term>
<term>Significant covariates</term>
<term>Significant difference</term>
<term>Significant effect</term>
<term>Simulation</term>
<term>Simulation model</term>
<term>Single center</term>
<term>Single dose</term>
<term>Smoker</term>
<term>Smoking dependence</term>
<term>Smoking status</term>
<term>Solabegron exposure</term>
<term>Sparse samples</term>
<term>Sparse sampling</term>
<term>Spinal cord tissue</term>
<term>Standard dose</term>
<term>State university</term>
<term>Statin</term>
<term>Steady state</term>
<term>Stress parameters</term>
<term>Study logistics</term>
<term>Subcu taneous</term>
<term>Subcutaneous</term>
<term>Subcutaneous adipo</term>
<term>Subj</term>
<term>Subj ects</term>
<term>Subje</term>
<term>Subjec</term>
<term>Suitable laboratory tests</term>
<term>Sunil kapur</term>
<term>Tablet</term>
<term>Tarek leil</term>
<term>Target population</term>
<term>Technical university</term>
<term>Testicular function</term>
<term>Therapeutics</term>
<term>Thma patients</term>
<term>Tic</term>
<term>Tients</term>
<term>Tile assay</term>
<term>Time course</term>
<term>Ting</term>
<term>Tion</term>
<term>Tions</term>
<term>Tive</term>
<term>Tment</term>
<term>Tolerab ility</term>
<term>Tolerability</term>
<term>Total error</term>
<term>Trans ient</term>
<term>Trea</term>
<term>Trea tment</term>
<term>Treatme</term>
<term>Trial simulator</term>
<term>Trospium</term>
<term>Trospium exposure</term>
<term>Tudy</term>
<term>Ubject variab ility</term>
<term>Uced</term>
<term>Ular</term>
<term>Ulation</term>
<term>Unive</term>
<term>Univers</term>
<term>University college</term>
<term>Upcoming phase</term>
<term>Upper bounds</term>
<term>Urinary</term>
<term>Urinary excretion</term>
<term>Urine</term>
<term>Urine flow</term>
<term>Urine samples</term>
<term>Vancomycin</term>
<term>Varia</term>
<term>Varia tion</term>
<term>Variab</term>
<term>Variab ility</term>
<term>Variability</term>
<term>Venla faxine</term>
<term>Virginia commonwealth university</term>
<term>Vital signs</term>
<term>Vivo</term>
<term>Vivo activity</term>
<term>Warfarin</term>
<term>Weight gain</term>
<term>Weight range</term>
<term>Whitehouse station</term>
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