The postnatal acquisition of factors which affect the influenza haemagglutination-inhibition test
Identifieur interne : 001680 ( Main/Curation ); précédent : 001679; suivant : 001681The postnatal acquisition of factors which affect the influenza haemagglutination-inhibition test
Auteurs : P. C. A. Grint ; S. Argent ; R. B. HeathSource :
- Journal of Hygiene [ 0022-1724 ] ; 1982-10.
Abstract
Levels of maternally transferred antibodies against the surface antigen of the A/Texas/1/77 strain of influenza virus showed the expected decline during infancy when measured by complement fixation (CF). However, this decline was not observed when these antibodies were measured by haemagglutination-inhibition (HI). It has been postulated that this discrepancy is due to the acquisition, in the early days of life, of non-specific serum factors which increase the HI activity of sera. The levels of these factors were determined indirectly by calculating HI: CF ratios and it was shown that the factors are rapidly acquired by children between the fifth and twentieth week of life.
Url:
- https://api.istex.fr/ark:/67375/6GQ-KK3TL2B3-8/fulltext.pdf
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134217
DOI: 10.1017/S0022172400070868
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<front><div type="abstract" xml:lang="en"><p>Levels of maternally transferred antibodies against the surface antigen of the A/Texas/1/77 strain of influenza virus showed the expected decline during infancy when measured by complement fixation (CF). However, this decline was not observed when these antibodies were measured by haemagglutination-inhibition (HI). It has been postulated that this discrepancy is due to the acquisition, in the early days of life, of non-specific serum factors which increase the HI activity of sera. The levels of these factors were determined indirectly by calculating HI:CF ratios and it was shown that the factors are rapidly acquired by children between the fifth and twentieth week of life.</p>
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