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The postnatal acquisition of factors which affect the influenza haemagglutination-inhibition test.

Identifieur interne : 000238 ( Pmc/Curation ); précédent : 000237; suivant : 000239

The postnatal acquisition of factors which affect the influenza haemagglutination-inhibition test.

Auteurs : P. C. Grint ; S. Argent ; R. B. Heath

Source :

RBID : PMC:2134217

Abstract

Levels of maternally transferred antibodies against the surface antigen of the A/Texas/1/77 strain of influenza virus showed the expected decline during infancy when measured by complement fixation (CF). However, this decline was not observed when these antibodies were measured by haemagglutination-inhibition (HI). It has been postulated that this discrepancy is due to the acquisition, in the early days of life, of non-specific serum factors which increase the HI activity of sera. The levels of these factors were determined indirectly by calculating HI:CF ratios and it was shown that the factors are rapidly acquired by children between the fifth and twentieth week of life.


Url:
PubMed: 7130707
PubMed Central: 2134217

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PMC:2134217

Le document en format XML

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<p>Levels of maternally transferred antibodies against the surface antigen of the A/Texas/1/77 strain of influenza virus showed the expected decline during infancy when measured by complement fixation (CF). However, this decline was not observed when these antibodies were measured by haemagglutination-inhibition (HI). It has been postulated that this discrepancy is due to the acquisition, in the early days of life, of non-specific serum factors which increase the HI activity of sera. The levels of these factors were determined indirectly by calculating HI:CF ratios and it was shown that the factors are rapidly acquired by children between the fifth and twentieth week of life.</p>
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<month>10</month>
<year>1982</year>
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<volume>89</volume>
<issue>2</issue>
<fpage>329</fpage>
<lpage>334</lpage>
<abstract>
<p>Levels of maternally transferred antibodies against the surface antigen of the A/Texas/1/77 strain of influenza virus showed the expected decline during infancy when measured by complement fixation (CF). However, this decline was not observed when these antibodies were measured by haemagglutination-inhibition (HI). It has been postulated that this discrepancy is due to the acquisition, in the early days of life, of non-specific serum factors which increase the HI activity of sera. The levels of these factors were determined indirectly by calculating HI:CF ratios and it was shown that the factors are rapidly acquired by children between the fifth and twentieth week of life.</p>
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