Haemagglutinin-esterase protein (HE) of murine corona virus: DVIMD (diarrhea virus of infant mice)
Identifieur interne : 001206 ( Main/Curation ); précédent : 001205; suivant : 001207Haemagglutinin-esterase protein (HE) of murine corona virus: DVIMD (diarrhea virus of infant mice)
Auteurs : K. Sugiyama [Japon] ; M. Kasai [Japon] ; S. Kato [Japon] ; H. Kasai [Japon] ; K. Hatakeyama [Japon]Source :
- Archives of Virology [ 0304-8608 ] ; 1998-07-01.
Descripteurs français
- KwdFr :
- Acetylesterase (analyse), Acetylesterase (isolement et purification), Animaux, Coronavirus (enzymologie), Femelle, Hémagglutinines virales (analyse), Hémagglutinines virales (isolement et purification), Hémagglutinines virales (physiologie), Protéines de fusion virale, Protéines virales (analyse), Protéines virales (isolement et purification), Protéines virales (physiologie), Souris, Souris de lignée BALB C, Spécificité du substrat.
- MESH :
- analyse : Acetylesterase, Hémagglutinines virales, Protéines virales.
- enzymologie : Coronavirus.
- isolement et purification : Acetylesterase, Hémagglutinines virales, Protéines virales.
- physiologie : Hémagglutinines virales, Protéines virales.
- Animaux, Femelle, Protéines de fusion virale, Souris, Souris de lignée BALB C, Spécificité du substrat.
- Pascal (Inist)
English descriptors
- KwdEn :
- Acetylesterase (analysis), Acetylesterase (isolation & purification), Animals, Characterization, Coronavirus (enzymology), Enzymatic activity, Esterases, Female, Hemagglutinin, Hemagglutinins, Viral (analysis), Hemagglutinins, Viral (isolation & purification), Hemagglutinins, Viral (physiology), Mice, Mice, Inbred BALB C, Murine hepatitis virus, Substrate Specificity, Substrate specificity, Viral Fusion Proteins, Viral Proteins (analysis), Viral Proteins (isolation & purification), Viral Proteins (physiology).
- MESH :
- chemical , analysis : Acetylesterase, Hemagglutinins, Viral, Viral Proteins.
- chemical , isolation & purification : Acetylesterase, Hemagglutinins, Viral, Viral Proteins.
- enzymology : Coronavirus.
- chemical , physiology : Hemagglutinins, Viral, Viral Proteins.
- Animals, Female, Mice, Mice, Inbred BALB C, Substrate Specificity, Viral Fusion Proteins.
Abstract
Summary: The acetylesterase (AE) activity of DVIM (diarrhea virus of infant mice) was assigned to the haemagglutinin-esterase (HE) protein. The substrate specificity was examined using the natural substrate bovine submaxillary mucin (BSM) and/or synthetic substrates p-nitrophenylacetate (p-NiA) and α-naphthylacetate (α-NA) and compared with several strains of MHV and influenza viruses. The AE of DVIM hydrolyzed the O-acetylester bond of BSM, and the two synthetic substrates p-NiA and α-NA in vitro. MHV-S reacted efficiently with both p-NiA and α-NA but less with BSM. Influenza virus (C/Miyagi/77) reacted with BSM efficiently, however reacted with p-NiA weakly, but not with α-NA at all. Thus, the AE-reactivity of DVIM was distinctly different from that of MHV-S and influenza C virus, suggesting that the AE of HE may have a modified function. Isolation of HE by the treatment with non ionic detergent NP40, resulted in globules approximately 5 nm in diameter. DVIM-binding proteins were demonstrated in the plasma membrane of mouse intestinal brush-border cells and hepatocytes. The same protein was recognized by MHV-S and MHV-4. The cell membranes obtained from these target tissues were substrates for the AE of DVIM. The biological importance of the HE protein for DVIM is discussed.
Url:
DOI: 10.1007/s007050050395
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000305
- to stream Istex, to step Curation: Pour aller vers cette notice dans l'étape Curation :000285
- to stream Istex, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000394
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000728
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :000728
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000716
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :000E94
- to stream Ncbi, to step Curation: Pour aller vers cette notice dans l'étape Curation :000E94
- to stream Ncbi, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000E94
- to stream Main, to step Merge: Pour aller vers cette notice dans l'étape Curation :001219
- to stream PascalFrancis, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000061
- to stream PascalFrancis, to step Curation: Pour aller vers cette notice dans l'étape Curation :000069
- to stream PascalFrancis, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000059
- to stream Main, to step Merge: Pour aller vers cette notice dans l'étape Curation :001225
Links to Exploration step
ISTEX:8FCC5CAFB0AE66AF9BBB6F375D73A434555BE1DBLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Haemagglutinin-esterase protein (HE) of murine corona virus: DVIMD (diarrhea virus of infant mice)</title>
<author><name sortKey="Sugiyama, K" sort="Sugiyama, K" uniqKey="Sugiyama K" first="K." last="Sugiyama">K. Sugiyama</name>
</author>
<author><name sortKey="Kasai, M" sort="Kasai, M" uniqKey="Kasai M" first="M." last="Kasai">M. Kasai</name>
</author>
<author><name sortKey="Kato, S" sort="Kato, S" uniqKey="Kato S" first="S." last="Kato">S. Kato</name>
</author>
<author><name sortKey="Kasai, H" sort="Kasai, H" uniqKey="Kasai H" first="H." last="Kasai">H. Kasai</name>
</author>
<author><name sortKey="Hatakeyama, K" sort="Hatakeyama, K" uniqKey="Hatakeyama K" first="K." last="Hatakeyama">K. Hatakeyama</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:8FCC5CAFB0AE66AF9BBB6F375D73A434555BE1DB</idno>
<date when="1998" year="1998">1998</date>
<idno type="doi">10.1007/s007050050395</idno>
<idno type="url">https://api.istex.fr/ark:/67375/VQC-CR9M0C0V-V/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000305</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000305</idno>
<idno type="wicri:Area/Istex/Curation">000285</idno>
<idno type="wicri:Area/Istex/Checkpoint">000394</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000394</idno>
<idno type="wicri:doubleKey">0304-8608:1998:Sugiyama K:haemagglutinin:esterase:protein</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:9739331</idno>
<idno type="wicri:Area/PubMed/Corpus">000728</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000728</idno>
<idno type="wicri:Area/PubMed/Curation">000728</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000728</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000716</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000716</idno>
<idno type="wicri:Area/Ncbi/Merge">000E94</idno>
<idno type="wicri:Area/Ncbi/Curation">000E94</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000E94</idno>
<idno type="wicri:doubleKey">0304-8608:1998:Sugiyama K:haemagglutinin:esterase:protein</idno>
<idno type="wicri:Area/Main/Merge">001219</idno>
<idno type="wicri:source">INIST</idno>
<idno type="RBID">Pascal:98-0511618</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000061</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000069</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000059</idno>
<idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000059</idno>
<idno type="wicri:doubleKey">0304-8608:1998:Sugiyama K:haemagglutinin:esterase:protein</idno>
<idno type="wicri:Area/Main/Merge">001225</idno>
<idno type="wicri:Area/Main/Curation">001206</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Haemagglutinin-esterase protein (HE) of murine corona virus: DVIMD (diarrhea virus of infant mice)</title>
<author><name sortKey="Sugiyama, K" sort="Sugiyama, K" uniqKey="Sugiyama K" first="K." last="Sugiyama">K. Sugiyama</name>
<affiliation wicri:level="1"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Biology, Faculty of Science, Hirosaki University, Hirosaki, Japan</wicri:regionArea>
<wicri:noRegion>Japan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kasai, M" sort="Kasai, M" uniqKey="Kasai M" first="M." last="Kasai">M. Kasai</name>
<affiliation wicri:level="1"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Biology, Faculty of Science, Hirosaki University, Hirosaki, Japan</wicri:regionArea>
<wicri:noRegion>Japan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kato, S" sort="Kato, S" uniqKey="Kato S" first="S." last="Kato">S. Kato</name>
<affiliation wicri:level="1"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Biology, Faculty of Science, Hirosaki University, Hirosaki, Japan</wicri:regionArea>
<wicri:noRegion>Japan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kasai, H" sort="Kasai, H" uniqKey="Kasai H" first="H." last="Kasai">H. Kasai</name>
<affiliation wicri:level="1"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Biology, Faculty of Science, Hirosaki University, Hirosaki, Japan</wicri:regionArea>
<wicri:noRegion>Japan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hatakeyama, K" sort="Hatakeyama, K" uniqKey="Hatakeyama K" first="K." last="Hatakeyama">K. Hatakeyama</name>
<affiliation wicri:level="1"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Biology, Faculty of Science, Hirosaki University, Hirosaki, Japan</wicri:regionArea>
<wicri:noRegion>Japan</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Archives of Virology</title>
<title level="j" type="abbrev">Arch. Virol.</title>
<idno type="ISSN">0304-8608</idno>
<idno type="eISSN">1432-8798</idno>
<imprint><publisher>Springer-Verlag</publisher>
<pubPlace>Vienna</pubPlace>
<date type="published" when="1998-07-01">1998-07-01</date>
<biblScope unit="volume">143</biblScope>
<biblScope unit="issue">8</biblScope>
<biblScope unit="page" from="1523">1523</biblScope>
<biblScope unit="page" to="1534">1534</biblScope>
</imprint>
<idno type="ISSN">0304-8608</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0304-8608</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acetylesterase (analysis)</term>
<term>Acetylesterase (isolation & purification)</term>
<term>Animals</term>
<term>Characterization</term>
<term>Coronavirus (enzymology)</term>
<term>Enzymatic activity</term>
<term>Esterases</term>
<term>Female</term>
<term>Hemagglutinin</term>
<term>Hemagglutinins, Viral (analysis)</term>
<term>Hemagglutinins, Viral (isolation & purification)</term>
<term>Hemagglutinins, Viral (physiology)</term>
<term>Mice</term>
<term>Mice, Inbred BALB C</term>
<term>Murine hepatitis virus</term>
<term>Substrate Specificity</term>
<term>Substrate specificity</term>
<term>Viral Fusion Proteins</term>
<term>Viral Proteins (analysis)</term>
<term>Viral Proteins (isolation & purification)</term>
<term>Viral Proteins (physiology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Acetylesterase (analyse)</term>
<term>Acetylesterase (isolement et purification)</term>
<term>Animaux</term>
<term>Coronavirus (enzymologie)</term>
<term>Femelle</term>
<term>Hémagglutinines virales (analyse)</term>
<term>Hémagglutinines virales (isolement et purification)</term>
<term>Hémagglutinines virales (physiologie)</term>
<term>Protéines de fusion virale</term>
<term>Protéines virales (analyse)</term>
<term>Protéines virales (isolement et purification)</term>
<term>Protéines virales (physiologie)</term>
<term>Souris</term>
<term>Souris de lignée BALB C</term>
<term>Spécificité du substrat</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Acetylesterase</term>
<term>Hemagglutinins, Viral</term>
<term>Viral Proteins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="isolation & purification" xml:lang="en"><term>Acetylesterase</term>
<term>Hemagglutinins, Viral</term>
<term>Viral Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Acetylesterase</term>
<term>Hémagglutinines virales</term>
<term>Protéines virales</term>
</keywords>
<keywords scheme="MESH" qualifier="enzymologie" xml:lang="fr"><term>Coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="enzymology" xml:lang="en"><term>Coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Acetylesterase</term>
<term>Hémagglutinines virales</term>
<term>Protéines virales</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Hémagglutinines virales</term>
<term>Protéines virales</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="physiology" xml:lang="en"><term>Hemagglutinins, Viral</term>
<term>Viral Proteins</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Female</term>
<term>Mice</term>
<term>Mice, Inbred BALB C</term>
<term>Substrate Specificity</term>
<term>Viral Fusion Proteins</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Femelle</term>
<term>Protéines de fusion virale</term>
<term>Souris</term>
<term>Souris de lignée BALB C</term>
<term>Spécificité du substrat</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Activité enzymatique</term>
<term>Caractérisation</term>
<term>Esterases</term>
<term>Hémagglutinine</term>
<term>Spécificité substrat</term>
<term>Virus hépatite murine</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Summary: The acetylesterase (AE) activity of DVIM (diarrhea virus of infant mice) was assigned to the haemagglutinin-esterase (HE) protein. The substrate specificity was examined using the natural substrate bovine submaxillary mucin (BSM) and/or synthetic substrates p-nitrophenylacetate (p-NiA) and α-naphthylacetate (α-NA) and compared with several strains of MHV and influenza viruses. The AE of DVIM hydrolyzed the O-acetylester bond of BSM, and the two synthetic substrates p-NiA and α-NA in vitro. MHV-S reacted efficiently with both p-NiA and α-NA but less with BSM. Influenza virus (C/Miyagi/77) reacted with BSM efficiently, however reacted with p-NiA weakly, but not with α-NA at all. Thus, the AE-reactivity of DVIM was distinctly different from that of MHV-S and influenza C virus, suggesting that the AE of HE may have a modified function. Isolation of HE by the treatment with non ionic detergent NP40, resulted in globules approximately 5 nm in diameter. DVIM-binding proteins were demonstrated in the plasma membrane of mouse intestinal brush-border cells and hepatocytes. The same protein was recognized by MHV-S and MHV-4. The cell membranes obtained from these target tissues were substrates for the AE of DVIM. The biological importance of the HE protein for DVIM is discussed.</div>
</front>
</TEI>
<double idat="0304-8608:1998:Sugiyama K:haemagglutinin:esterase:protein"><INIST><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Haemagglutinin-esterase protein (HE) of murine corona virus : DVIM (diarrhea virus of infant mice)</title>
<author><name sortKey="Sugiyama, K" sort="Sugiyama, K" uniqKey="Sugiyama K" first="K." last="Sugiyama">K. Sugiyama</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Biology, Faculty of Science, Hirosaki University</s1>
<s2>Hirosaki</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<wicri:noRegion>Hirosaki</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kasai, M" sort="Kasai, M" uniqKey="Kasai M" first="M." last="Kasai">M. Kasai</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Biology, Faculty of Science, Hirosaki University</s1>
<s2>Hirosaki</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<wicri:noRegion>Hirosaki</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kato, S" sort="Kato, S" uniqKey="Kato S" first="S." last="Kato">S. Kato</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Biology, Faculty of Science, Hirosaki University</s1>
<s2>Hirosaki</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<wicri:noRegion>Hirosaki</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kasai, H" sort="Kasai, H" uniqKey="Kasai H" first="H." last="Kasai">H. Kasai</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Biology, Faculty of Science, Hirosaki University</s1>
<s2>Hirosaki</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<wicri:noRegion>Hirosaki</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hatakeyama, K" sort="Hatakeyama, K" uniqKey="Hatakeyama K" first="K." last="Hatakeyama">K. Hatakeyama</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Biology, Faculty of Science, Hirosaki University</s1>
<s2>Hirosaki</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<wicri:noRegion>Hirosaki</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">98-0511618</idno>
<date when="1998">1998</date>
<idno type="stanalyst">PASCAL 98-0511618 INIST</idno>
<idno type="RBID">Pascal:98-0511618</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000061</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000069</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000059</idno>
<idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000059</idno>
<idno type="wicri:doubleKey">0304-8608:1998:Sugiyama K:haemagglutinin:esterase:protein</idno>
<idno type="wicri:Area/Main/Merge">001225</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Haemagglutinin-esterase protein (HE) of murine corona virus : DVIM (diarrhea virus of infant mice)</title>
<author><name sortKey="Sugiyama, K" sort="Sugiyama, K" uniqKey="Sugiyama K" first="K." last="Sugiyama">K. Sugiyama</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Biology, Faculty of Science, Hirosaki University</s1>
<s2>Hirosaki</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<wicri:noRegion>Hirosaki</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kasai, M" sort="Kasai, M" uniqKey="Kasai M" first="M." last="Kasai">M. Kasai</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Biology, Faculty of Science, Hirosaki University</s1>
<s2>Hirosaki</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<wicri:noRegion>Hirosaki</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kato, S" sort="Kato, S" uniqKey="Kato S" first="S." last="Kato">S. Kato</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Biology, Faculty of Science, Hirosaki University</s1>
<s2>Hirosaki</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<wicri:noRegion>Hirosaki</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kasai, H" sort="Kasai, H" uniqKey="Kasai H" first="H." last="Kasai">H. Kasai</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Biology, Faculty of Science, Hirosaki University</s1>
<s2>Hirosaki</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<wicri:noRegion>Hirosaki</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hatakeyama, K" sort="Hatakeyama, K" uniqKey="Hatakeyama K" first="K." last="Hatakeyama">K. Hatakeyama</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Biology, Faculty of Science, Hirosaki University</s1>
<s2>Hirosaki</s2>
<s3>JPN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<wicri:noRegion>Hirosaki</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Archives of virology</title>
<title level="j" type="abbreviated">Arch. virol.</title>
<idno type="ISSN">0304-8608</idno>
<imprint><date when="1998">1998</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Archives of virology</title>
<title level="j" type="abbreviated">Arch. virol.</title>
<idno type="ISSN">0304-8608</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Characterization</term>
<term>Enzymatic activity</term>
<term>Esterases</term>
<term>Hemagglutinin</term>
<term>Murine hepatitis virus</term>
<term>Substrate specificity</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Virus hépatite murine</term>
<term>Hémagglutinine</term>
<term>Esterases</term>
<term>Caractérisation</term>
<term>Activité enzymatique</term>
<term>Spécificité substrat</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The acetylesterase (AE) activity of DVIM (diarrhea virus of infant mice) was assigned to the haemagglutinin-esterase (HE) protein. The substrate specificity was examined using the natural substrate bovine submaxillary mucin (BSM) and/or synthetic substrates p-nitrophenylacetate (p-NiA) and α-naphthylacetate (α-NA) and compared with several strains of MHV and influenza viruses. The AE of DVIM hydrolyzed the O-acetylester bond of BSM, and the two synthetic substrates p-NiA and α-NA in vitro. MHV-S reacted efficiently with both p-NiA and α-NA but less with BSM. Influenza virus (C/Miyagi/77) reacted with BSM efficiently, however reacted with p-NiA weakly, but not with α-NA at all. Thus, the AE-reactivity of DVIM was distinctly different from that of MHV-S and influenza C virus, suggesting that the AE of HE may have a modified function. Isolation of HE by the treatment with non ionic detergent NP40, resulted in globules approximately 5 nm in diameter. DVIM-binding proteins were demonstrated in the plasma membrane of mouse intestinal brush-border cells and hepatocytes. The same protein was recognized by MHV-S and MHV-4. The cell membranes obtained from these target tissues were substrates for the AE of DVIM. The biological importance of the HE protein for DVIM is discussed.</div>
</front>
</TEI>
</INIST>
<ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Haemagglutinin-esterase protein (HE) of murine corona virus: DVIMD (diarrhea virus of infant mice)</title>
<author><name sortKey="Sugiyama, K" sort="Sugiyama, K" uniqKey="Sugiyama K" first="K." last="Sugiyama">K. Sugiyama</name>
</author>
<author><name sortKey="Kasai, M" sort="Kasai, M" uniqKey="Kasai M" first="M." last="Kasai">M. Kasai</name>
</author>
<author><name sortKey="Kato, S" sort="Kato, S" uniqKey="Kato S" first="S." last="Kato">S. Kato</name>
</author>
<author><name sortKey="Kasai, H" sort="Kasai, H" uniqKey="Kasai H" first="H." last="Kasai">H. Kasai</name>
</author>
<author><name sortKey="Hatakeyama, K" sort="Hatakeyama, K" uniqKey="Hatakeyama K" first="K." last="Hatakeyama">K. Hatakeyama</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:8FCC5CAFB0AE66AF9BBB6F375D73A434555BE1DB</idno>
<date when="1998" year="1998">1998</date>
<idno type="doi">10.1007/s007050050395</idno>
<idno type="url">https://api.istex.fr/ark:/67375/VQC-CR9M0C0V-V/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000305</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000305</idno>
<idno type="wicri:Area/Istex/Curation">000285</idno>
<idno type="wicri:Area/Istex/Checkpoint">000394</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000394</idno>
<idno type="wicri:doubleKey">0304-8608:1998:Sugiyama K:haemagglutinin:esterase:protein</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:9739331</idno>
<idno type="wicri:Area/PubMed/Corpus">000728</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000728</idno>
<idno type="wicri:Area/PubMed/Curation">000728</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000728</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000716</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000716</idno>
<idno type="wicri:Area/Ncbi/Merge">000E94</idno>
<idno type="wicri:Area/Ncbi/Curation">000E94</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000E94</idno>
<idno type="wicri:doubleKey">0304-8608:1998:Sugiyama K:haemagglutinin:esterase:protein</idno>
<idno type="wicri:Area/Main/Merge">001219</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Haemagglutinin-esterase protein (HE) of murine corona virus: DVIMD (diarrhea virus of infant mice)</title>
<author><name sortKey="Sugiyama, K" sort="Sugiyama, K" uniqKey="Sugiyama K" first="K." last="Sugiyama">K. Sugiyama</name>
<affiliation wicri:level="1"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Biology, Faculty of Science, Hirosaki University, Hirosaki, Japan</wicri:regionArea>
<wicri:noRegion>Japan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kasai, M" sort="Kasai, M" uniqKey="Kasai M" first="M." last="Kasai">M. Kasai</name>
<affiliation wicri:level="1"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Biology, Faculty of Science, Hirosaki University, Hirosaki, Japan</wicri:regionArea>
<wicri:noRegion>Japan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kato, S" sort="Kato, S" uniqKey="Kato S" first="S." last="Kato">S. Kato</name>
<affiliation wicri:level="1"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Biology, Faculty of Science, Hirosaki University, Hirosaki, Japan</wicri:regionArea>
<wicri:noRegion>Japan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kasai, H" sort="Kasai, H" uniqKey="Kasai H" first="H." last="Kasai">H. Kasai</name>
<affiliation wicri:level="1"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Biology, Faculty of Science, Hirosaki University, Hirosaki, Japan</wicri:regionArea>
<wicri:noRegion>Japan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hatakeyama, K" sort="Hatakeyama, K" uniqKey="Hatakeyama K" first="K." last="Hatakeyama">K. Hatakeyama</name>
<affiliation wicri:level="1"><country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Biology, Faculty of Science, Hirosaki University, Hirosaki, Japan</wicri:regionArea>
<wicri:noRegion>Japan</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Archives of Virology</title>
<title level="j" type="abbrev">Arch. Virol.</title>
<idno type="ISSN">0304-8608</idno>
<idno type="eISSN">1432-8798</idno>
<imprint><publisher>Springer-Verlag</publisher>
<pubPlace>Vienna</pubPlace>
<date type="published" when="1998-07-01">1998-07-01</date>
<biblScope unit="volume">143</biblScope>
<biblScope unit="issue">8</biblScope>
<biblScope unit="page" from="1523">1523</biblScope>
<biblScope unit="page" to="1534">1534</biblScope>
</imprint>
<idno type="ISSN">0304-8608</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0304-8608</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acetylesterase (analysis)</term>
<term>Acetylesterase (isolation & purification)</term>
<term>Animals</term>
<term>Coronavirus (enzymology)</term>
<term>Female</term>
<term>Hemagglutinins, Viral (analysis)</term>
<term>Hemagglutinins, Viral (isolation & purification)</term>
<term>Hemagglutinins, Viral (physiology)</term>
<term>Mice</term>
<term>Mice, Inbred BALB C</term>
<term>Substrate Specificity</term>
<term>Viral Fusion Proteins</term>
<term>Viral Proteins (analysis)</term>
<term>Viral Proteins (isolation & purification)</term>
<term>Viral Proteins (physiology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Acetylesterase (analyse)</term>
<term>Acetylesterase (isolement et purification)</term>
<term>Animaux</term>
<term>Coronavirus (enzymologie)</term>
<term>Femelle</term>
<term>Hémagglutinines virales (analyse)</term>
<term>Hémagglutinines virales (isolement et purification)</term>
<term>Hémagglutinines virales (physiologie)</term>
<term>Protéines de fusion virale</term>
<term>Protéines virales (analyse)</term>
<term>Protéines virales (isolement et purification)</term>
<term>Protéines virales (physiologie)</term>
<term>Souris</term>
<term>Souris de lignée BALB C</term>
<term>Spécificité du substrat</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Acetylesterase</term>
<term>Hemagglutinins, Viral</term>
<term>Viral Proteins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="isolation & purification" xml:lang="en"><term>Acetylesterase</term>
<term>Hemagglutinins, Viral</term>
<term>Viral Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Acetylesterase</term>
<term>Hémagglutinines virales</term>
<term>Protéines virales</term>
</keywords>
<keywords scheme="MESH" qualifier="enzymologie" xml:lang="fr"><term>Coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="enzymology" xml:lang="en"><term>Coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Acetylesterase</term>
<term>Hémagglutinines virales</term>
<term>Protéines virales</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Hémagglutinines virales</term>
<term>Protéines virales</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="physiology" xml:lang="en"><term>Hemagglutinins, Viral</term>
<term>Viral Proteins</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Female</term>
<term>Mice</term>
<term>Mice, Inbred BALB C</term>
<term>Substrate Specificity</term>
<term>Viral Fusion Proteins</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Femelle</term>
<term>Protéines de fusion virale</term>
<term>Souris</term>
<term>Souris de lignée BALB C</term>
<term>Spécificité du substrat</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Summary: The acetylesterase (AE) activity of DVIM (diarrhea virus of infant mice) was assigned to the haemagglutinin-esterase (HE) protein. The substrate specificity was examined using the natural substrate bovine submaxillary mucin (BSM) and/or synthetic substrates p-nitrophenylacetate (p-NiA) and α-naphthylacetate (α-NA) and compared with several strains of MHV and influenza viruses. The AE of DVIM hydrolyzed the O-acetylester bond of BSM, and the two synthetic substrates p-NiA and α-NA in vitro. MHV-S reacted efficiently with both p-NiA and α-NA but less with BSM. Influenza virus (C/Miyagi/77) reacted with BSM efficiently, however reacted with p-NiA weakly, but not with α-NA at all. Thus, the AE-reactivity of DVIM was distinctly different from that of MHV-S and influenza C virus, suggesting that the AE of HE may have a modified function. Isolation of HE by the treatment with non ionic detergent NP40, resulted in globules approximately 5 nm in diameter. DVIM-binding proteins were demonstrated in the plasma membrane of mouse intestinal brush-border cells and hepatocytes. The same protein was recognized by MHV-S and MHV-4. The cell membranes obtained from these target tissues were substrates for the AE of DVIM. The biological importance of the HE protein for DVIM is discussed.</div>
</front>
</TEI>
</ISTEX>
</double>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV1/Data/Main/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001206 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Curation/biblio.hfd -nk 001206 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= CovidV1 |flux= Main |étape= Curation |type= RBID |clé= ISTEX:8FCC5CAFB0AE66AF9BBB6F375D73A434555BE1DB |texte= Haemagglutinin-esterase protein (HE) of murine corona virus: DVIMD (diarrhea virus of infant mice) }}
This area was generated with Dilib version V0.6.33. |