Marine Sponges as Pharmacy
Identifieur interne : 001014 ( Main/Curation ); précédent : 001013; suivant : 001015Marine Sponges as Pharmacy
Auteurs : Detmer Sipkema [Pays-Bas] ; Maurice C. R. Franssen [Pays-Bas] ; Ronald Osinga [Pays-Bas] ; Johannes Tramper [Pays-Bas] ; René H. Wijffels [Pays-Bas]Source :
- Marine Biotechnology [ 1436-2228 ] ; 2005-06-01.
English descriptors
- KwdEn :
Abstract
Abstract: Marine sponges have been considered as a gold mine during the past 50 years, with respect to the diversity of their secondary metabolites. The biological effects of new metabolites from sponges have been reported in hundreds of scientific papers, and they are reviewed here. Sponges have the potential to provide future drugs against important diseases, such as cancer, a range of viral diseases, malaria, and inflammations. Although the molecular mode of action of most metabolites is still unclear, for a substantial number of compounds the mechanisms by which they interfere with the pathogenesis of a wide range of diseases have been reported. This knowledge is one of the key factors necessary to transform bioactive compounds into medicines. Sponges produce a plethora of chemical compounds with widely varying carbon skeletons, which have been found to interfere with pathogenesis at many different points. The fact that a particular disease can be fought at different points increases the chance of developing selective drugs for specific targets.
Url:
DOI: 10.1007/s10126-004-0405-5
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000851
- to stream Istex, to step Curation: Pour aller vers cette notice dans l'étape Curation :000831
- to stream Istex, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000260
- to stream Main, to step Merge: Pour aller vers cette notice dans l'étape Curation :001024
Links to Exploration step
ISTEX:1540923A5B8D059015E6BAB730A5F8576710FF9CLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Marine Sponges as Pharmacy</title>
<author><name sortKey="Sipkema, Detmer" sort="Sipkema, Detmer" uniqKey="Sipkema D" first="Detmer" last="Sipkema">Detmer Sipkema</name>
</author>
<author><name sortKey="Franssen, Maurice C R" sort="Franssen, Maurice C R" uniqKey="Franssen M" first="Maurice C. R." last="Franssen">Maurice C. R. Franssen</name>
</author>
<author><name sortKey="Osinga, Ronald" sort="Osinga, Ronald" uniqKey="Osinga R" first="Ronald" last="Osinga">Ronald Osinga</name>
</author>
<author><name sortKey="Tramper, Johannes" sort="Tramper, Johannes" uniqKey="Tramper J" first="Johannes" last="Tramper">Johannes Tramper</name>
</author>
<author><name sortKey="Wijffels, Rene H" sort="Wijffels, Rene H" uniqKey="Wijffels R" first="René H." last="Wijffels">René H. Wijffels</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:1540923A5B8D059015E6BAB730A5F8576710FF9C</idno>
<date when="2005" year="2005">2005</date>
<idno type="doi">10.1007/s10126-004-0405-5</idno>
<idno type="url">https://api.istex.fr/ark:/67375/VQC-4V4S0VQC-X/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000851</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000851</idno>
<idno type="wicri:Area/Istex/Curation">000831</idno>
<idno type="wicri:Area/Istex/Checkpoint">000260</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000260</idno>
<idno type="wicri:doubleKey">1436-2228:2005:Sipkema D:marine:sponges:as</idno>
<idno type="wicri:Area/Main/Merge">001024</idno>
<idno type="wicri:Area/Main/Curation">001014</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Marine Sponges as Pharmacy</title>
<author><name sortKey="Sipkema, Detmer" sort="Sipkema, Detmer" uniqKey="Sipkema D" first="Detmer" last="Sipkema">Detmer Sipkema</name>
<affiliation wicri:level="4"><country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Wageningen University, Food and Bioprocess Engineering Group, 8129, 6700 EV Wageningen</wicri:regionArea>
<orgName type="university">Université de Wageningue</orgName>
<placeName><settlement type="city">Wageningue</settlement>
<region nuts="2">Gueldre (province)</region>
</placeName>
</affiliation>
<affiliation wicri:level="1"><country wicri:rule="url">Pays-Bas</country>
</affiliation>
</author>
<author><name sortKey="Franssen, Maurice C R" sort="Franssen, Maurice C R" uniqKey="Franssen M" first="Maurice C. R." last="Franssen">Maurice C. R. Franssen</name>
<affiliation wicri:level="4"><country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Wageningen University, Laboratory of Organic Chemistry, Dreijenplein 8, 6703 HB Wageningen</wicri:regionArea>
<orgName type="university">Université de Wageningue</orgName>
<placeName><settlement type="city">Wageningue</settlement>
<region nuts="2">Gueldre (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Osinga, Ronald" sort="Osinga, Ronald" uniqKey="Osinga R" first="Ronald" last="Osinga">Ronald Osinga</name>
<affiliation wicri:level="4"><country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Wageningen University, Food and Bioprocess Engineering Group, 8129, 6700 EV Wageningen</wicri:regionArea>
<orgName type="university">Université de Wageningue</orgName>
<placeName><settlement type="city">Wageningue</settlement>
<region nuts="2">Gueldre (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Tramper, Johannes" sort="Tramper, Johannes" uniqKey="Tramper J" first="Johannes" last="Tramper">Johannes Tramper</name>
<affiliation wicri:level="4"><country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Wageningen University, Food and Bioprocess Engineering Group, 8129, 6700 EV Wageningen</wicri:regionArea>
<orgName type="university">Université de Wageningue</orgName>
<placeName><settlement type="city">Wageningue</settlement>
<region nuts="2">Gueldre (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wijffels, Rene H" sort="Wijffels, Rene H" uniqKey="Wijffels R" first="René H." last="Wijffels">René H. Wijffels</name>
<affiliation wicri:level="4"><country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Wageningen University, Food and Bioprocess Engineering Group, 8129, 6700 EV Wageningen</wicri:regionArea>
<orgName type="university">Université de Wageningue</orgName>
<placeName><settlement type="city">Wageningue</settlement>
<region nuts="2">Gueldre (province)</region>
</placeName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Marine Biotechnology</title>
<title level="j" type="abbrev">Mar Biotechnol</title>
<idno type="ISSN">1436-2228</idno>
<idno type="eISSN">1436-2236</idno>
<imprint><publisher>Springer-Verlag; www.springer-ny.com</publisher>
<pubPlace>New York</pubPlace>
<date type="published" when="2005-06-01">2005-06-01</date>
<biblScope unit="volume">7</biblScope>
<biblScope unit="issue">3</biblScope>
<biblScope unit="page" from="142">142</biblScope>
<biblScope unit="page" to="162">162</biblScope>
</imprint>
<idno type="ISSN">1436-2228</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">1436-2228</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>cancer</term>
<term>inflammation</term>
<term>natural product</term>
<term>sponge medicine</term>
<term>virus</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Abstract: Marine sponges have been considered as a gold mine during the past 50 years, with respect to the diversity of their secondary metabolites. The biological effects of new metabolites from sponges have been reported in hundreds of scientific papers, and they are reviewed here. Sponges have the potential to provide future drugs against important diseases, such as cancer, a range of viral diseases, malaria, and inflammations. Although the molecular mode of action of most metabolites is still unclear, for a substantial number of compounds the mechanisms by which they interfere with the pathogenesis of a wide range of diseases have been reported. This knowledge is one of the key factors necessary to transform bioactive compounds into medicines. Sponges produce a plethora of chemical compounds with widely varying carbon skeletons, which have been found to interfere with pathogenesis at many different points. The fact that a particular disease can be fought at different points increases the chance of developing selective drugs for specific targets.</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV1/Data/Main/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001014 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Curation/biblio.hfd -nk 001014 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= CovidV1 |flux= Main |étape= Curation |type= RBID |clé= ISTEX:1540923A5B8D059015E6BAB730A5F8576710FF9C |texte= Marine Sponges as Pharmacy }}
This area was generated with Dilib version V0.6.33. |