News and Traditional Indications from Short Daily Dialysis: Different Schemes to Optimized ESF Response
Identifieur interne : 000968 ( Istex/Corpus ); précédent : 000967; suivant : 000969News and Traditional Indications from Short Daily Dialysis: Different Schemes to Optimized ESF Response
Auteurs : G. Barril ; E. Besada ; P. Caro ; F. Dapena ; P. Sanz ; S. Cigarran ; R. SelgasSource :
- Hemodialysis International [ 1492-7535 ] ; 2004-01.
Abstract
Interest in quotidian (daily) hemodialysis (DHD) seems to be growing. DHD improves quality of life, blood pressure control, and nutrition, and decreases the need of medications, including erythropoiesis stimulating factors (ESF). We evaluate the short daily dialysis (SDHD) efficacy in 14 patients in conventional hemodialysis (HD) (3 weekly sessions/4 h), mean age 52.1 years, range 25–75, 10 males and 4 females, and found that they needed to increase dialysis efficiency by different medical indications: in 11 cases traditional indications – 5 cases with hypertensive myocardiopathy and severe LVH (2 of them with low left ventricle ejection fraction), 2 cases with symptomatic, ischemic cardiopathy 2 patient with big body‐surface area and elevated phosphorus levels, and 2 patients by inadequate dialysis (infradialysis conditioning malnutrition status) secondary to HD with permanent catheter. In one female (25 yr old), SDHD was prescribed to improve cardiac toxicity secondary to chemotherapy for acute promyelocytic leukemia. The index resistance of ESF decreased since the first month, and the Aranesp doses decreased by more than 40%. 1 male (49 years) with nephrogenic fibrosing dermopathy showed skin lesions with osteoblastic transformation. The skin lesions were improving since the first week, obtaining a decrease of the index resistance ESF higher than 60% in the first month. 1 male with symptomatic obstructive hypertrophic myocardiopathy showed improvement of symptoms and quality of life since the first weeks, as well as echocardiograpic signs and improvement in Hb levels and decreasing dose of ESF. The schedule in all of them was 5–6 days/week sessions between 2.15 h and 3 h, depending on body‐surface area. To obtain a weekly Kt/V nearest to 4, HD sessions were realized in the hospital (7 pts) or in satellite unit (7 pts). The time remaining in this schedule was between 1 and 42 months. All the patients showed clinical improvement, subjective and objective, since the first week of start of SDHD. 3 patients could be included in Tx waiting list again. Anemia improved, decreasing index resistance of ESF. In relation with this, the time necessary to improve the response to ESF was different, showing a decrease in the first month higher than 40% in two cases dialyzing with a membrane high‐flux with pore size 100 A, appearing high Hb levels also in a polycystic patient always without ESF. We observed by analyzing the results in 12 stable patients; the patients with high‐flux dialyzers showed better response to ESF. Perhaps it could offer a better clearance of large molecules (inhibitor erythropoiesis factor and high molecular weight toxins) that participate to respond to ESF. Conclusion: Our experience shows new indications for SDHD with very good results. Anemia was improved in relation with SDHD, when synthetic high‐flux membranes and high pore size were used.
Url:
DOI: 10.1111/j.1492-7535.2004.0085r.x
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ISTEX:029A05ED3C6396849003366B88A2917BD14001DALe document en format XML
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Ruber</mods:affiliation></affiliation></author><author><name sortKey="Sanz, P" sort="Sanz, P" uniqKey="Sanz P" first="P." last="Sanz">P. Sanz</name><affiliation><mods:affiliation>Department of Nephrology H. U. Princesa</mods:affiliation></affiliation></author><author><name sortKey="Cigarran, S" sort="Cigarran, S" uniqKey="Cigarran S" first="S." last="Cigarran">S. Cigarran</name><affiliation><mods:affiliation>El Pilar FMC, Madrid, Spain.</mods:affiliation></affiliation></author><author><name sortKey="Selgas, R" sort="Selgas, R" uniqKey="Selgas R" first="R." last="Selgas">R. Selgas</name><affiliation><mods:affiliation>Department of Nephrology H. U. 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Princesa</mods:affiliation></affiliation></author><author><name sortKey="Besada, E" sort="Besada, E" uniqKey="Besada E" first="E." last="Besada">E. Besada</name><affiliation><mods:affiliation>Asdho FMC Torrejón</mods:affiliation></affiliation></author><author><name sortKey="Caro, P" sort="Caro, P" uniqKey="Caro P" first="P." last="Caro">P. Caro</name><affiliation><mods:affiliation>C. Ruber</mods:affiliation></affiliation></author><author><name sortKey="Dapena, F" sort="Dapena, F" uniqKey="Dapena F" first="F." last="Dapena">F. Dapena</name><affiliation><mods:affiliation>C. Ruber</mods:affiliation></affiliation></author><author><name sortKey="Sanz, P" sort="Sanz, P" uniqKey="Sanz P" first="P." last="Sanz">P. Sanz</name><affiliation><mods:affiliation>Department of Nephrology H. U. Princesa</mods:affiliation></affiliation></author><author><name sortKey="Cigarran, S" sort="Cigarran, S" uniqKey="Cigarran S" first="S." last="Cigarran">S. Cigarran</name><affiliation><mods:affiliation>El Pilar FMC, Madrid, Spain.</mods:affiliation></affiliation></author><author><name sortKey="Selgas, R" sort="Selgas, R" uniqKey="Selgas R" first="R." last="Selgas">R. Selgas</name><affiliation><mods:affiliation>Department of Nephrology H. U. Princesa</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Hemodialysis International</title><title level="j" type="alt">HEMODIALYSIS INTERNATIONAL</title><idno type="ISSN">1492-7535</idno><idno type="eISSN">1542-4758</idno><imprint><biblScope unit="vol">8</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="85">85</biblScope><biblScope unit="page" to="85">85</biblScope><biblScope unit="page-count">100</biblScope><publisher>Blackwell Science Inc</publisher><pubPlace>Oxford, UK; Malden, USA</pubPlace><date type="published" when="2004-01">2004-01</date></imprint><idno type="ISSN">1492-7535</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1492-7535</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Interest in quotidian (daily) hemodialysis (DHD) seems to be growing. DHD improves quality of life, blood pressure control, and nutrition, and decreases the need of medications, including erythropoiesis stimulating factors (ESF). We evaluate the short daily dialysis (SDHD) efficacy in 14 patients in conventional hemodialysis (HD) (3 weekly sessions/4 h), mean age 52.1 years, range 25–75, 10 males and 4 females, and found that they needed to increase dialysis efficiency by different medical indications: in 11 cases traditional indications – 5 cases with hypertensive myocardiopathy and severe LVH (2 of them with low left ventricle ejection fraction), 2 cases with symptomatic, ischemic cardiopathy 2 patient with big body‐surface area and elevated phosphorus levels, and 2 patients by inadequate dialysis (infradialysis conditioning malnutrition status) secondary to HD with permanent catheter. In one female (25 yr old), SDHD was prescribed to improve cardiac toxicity secondary to chemotherapy for acute promyelocytic leukemia. The index resistance of ESF decreased since the first month, and the Aranesp doses decreased by more than 40%. 1 male (49 years) with nephrogenic fibrosing dermopathy showed skin lesions with osteoblastic transformation. The skin lesions were improving since the first week, obtaining a decrease of the index resistance ESF higher than 60% in the first month. 1 male with symptomatic obstructive hypertrophic myocardiopathy showed improvement of symptoms and quality of life since the first weeks, as well as echocardiograpic signs and improvement in Hb levels and decreasing dose of ESF. The schedule in all of them was 5–6 days/week sessions between 2.15 h and 3 h, depending on body‐surface area. To obtain a weekly Kt/V nearest to 4, HD sessions were realized in the hospital (7 pts) or in satellite unit (7 pts). The time remaining in this schedule was between 1 and 42 months. All the patients showed clinical improvement, subjective and objective, since the first week of start of SDHD. 3 patients could be included in Tx waiting list again. Anemia improved, decreasing index resistance of ESF. In relation with this, the time necessary to improve the response to ESF was different, showing a decrease in the first month higher than 40% in two cases dialyzing with a membrane high‐flux with pore size 100 A, appearing high Hb levels also in a polycystic patient always without ESF. We observed by analyzing the results in 12 stable patients; the patients with high‐flux dialyzers showed better response to ESF. Perhaps it could offer a better clearance of large molecules (inhibitor erythropoiesis factor and high molecular weight toxins) that participate to respond to ESF. Conclusion: Our experience shows new indications for SDHD with very good results. 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donor</json:string><json:string>tremendous improvement</json:string><json:string>significant independent predictor</json:string><json:string>individual scale</json:string><json:string>general hospital</json:string><json:string>heart failure</json:string><json:string>tesio catheter</json:string><json:string>dialysis catheter</json:string><json:string>average staff time</json:string><json:string>extracorporeal serum</json:string><json:string>urea kinetics</json:string><json:string>body size</json:string><json:string>urea mass</json:string><json:string>dialysis modality</json:string><json:string>initial flow</json:string><json:string>vascular surgeon</json:string><json:string>causative agent</json:string><json:string>precautionary measure</json:string><json:string>peer pressure</json:string><json:string>syndrome</json:string><json:string>ontario</json:string><json:string>albumin</json:string><json:string>clearance</json:string><json:string>mortality</json:string><json:string>complication</json:string><json:string>hemoglobin</json:string><json:string>diabetes</json:string><json:string>infection</json:string></teeft></keywords><author><json:item><name>G. Barril</name><affiliations><json:string>Department of Nephrology H. U. Princesa</json:string></affiliations></json:item><json:item><name>E. Besada</name><affiliations><json:string>Asdho FMC Torrejón</json:string></affiliations></json:item><json:item><name>P. Caro</name><affiliations><json:string>C. Ruber</json:string></affiliations></json:item><json:item><name>F. Dapena</name><affiliations><json:string>C. Ruber</json:string></affiliations></json:item><json:item><name>P. Sanz</name><affiliations><json:string>Department of Nephrology H. U. Princesa</json:string></affiliations></json:item><json:item><name>S. Cigarran</name><affiliations><json:string>El Pilar FMC, Madrid, Spain.</json:string></affiliations></json:item><json:item><name>R. Selgas</name><affiliations><json:string>Department of Nephrology H. U. Princesa</json:string></affiliations></json:item></author><articleId><json:string>HDI085R</json:string></articleId><arkIstex>ark:/67375/WNG-Q7V03D3L-0</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>abstract</json:string></originalGenre><abstract>Interest in quotidian (daily) hemodialysis (DHD) seems to be growing. DHD improves quality of life, blood pressure control, and nutrition, and decreases the need of medications, including erythropoiesis stimulating factors (ESF). We evaluate the short daily dialysis (SDHD) efficacy in 14 patients in conventional hemodialysis (HD) (3 weekly sessions/4 h), mean age 52.1 years, range 25–75, 10 males and 4 females, and found that they needed to increase dialysis efficiency by different medical indications: in 11 cases traditional indications – 5 cases with hypertensive myocardiopathy and severe LVH (2 of them with low left ventricle ejection fraction), 2 cases with symptomatic, ischemic cardiopathy 2 patient with big body‐surface area and elevated phosphorus levels, and 2 patients by inadequate dialysis (infradialysis conditioning malnutrition status) secondary to HD with permanent catheter. In one female (25 yr old), SDHD was prescribed to improve cardiac toxicity secondary to chemotherapy for acute promyelocytic leukemia. The index resistance of ESF decreased since the first month, and the Aranesp doses decreased by more than 40%. 1 male (49 years) with nephrogenic fibrosing dermopathy showed skin lesions with osteoblastic transformation. The skin lesions were improving since the first week, obtaining a decrease of the index resistance ESF higher than 60% in the first month. 1 male with symptomatic obstructive hypertrophic myocardiopathy showed improvement of symptoms and quality of life since the first weeks, as well as echocardiograpic signs and improvement in Hb levels and decreasing dose of ESF. The schedule in all of them was 5–6 days/week sessions between 2.15 h and 3 h, depending on body‐surface area. To obtain a weekly Kt/V nearest to 4, HD sessions were realized in the hospital (7 pts) or in satellite unit (7 pts). The time remaining in this schedule was between 1 and 42 months. All the patients showed clinical improvement, subjective and objective, since the first week of start of SDHD. 3 patients could be included in Tx waiting list again. Anemia improved, decreasing index resistance of ESF. In relation with this, the time necessary to improve the response to ESF was different, showing a decrease in the first month higher than 40% in two cases dialyzing with a membrane high‐flux with pore size 100 A, appearing high Hb levels also in a polycystic patient always without ESF. We observed by analyzing the results in 12 stable patients; the patients with high‐flux dialyzers showed better response to ESF. Perhaps it could offer a better clearance of large molecules (inhibitor erythropoiesis factor and high molecular weight toxins) that participate to respond to ESF. Conclusion: Our experience shows new indications for SDHD with very good results. Anemia was improved in relation with SDHD, when synthetic high‐flux membranes and high pore size were used.</abstract><qualityIndicators><score>10</score><pdfWordCount>24342</pdfWordCount><pdfCharCount>151874</pdfCharCount><pdfVersion>1.4</pdfVersion><pdfPageCount>33</pdfPageCount><pdfPageSize>595 x 782 pts</pdfPageSize><pdfWordsPerPage>738</pdfWordsPerPage><pdfText>true</pdfText><refBibsNative>false</refBibsNative><abstractWordCount>446</abstractWordCount><abstractCharCount>2908</abstractCharCount><keywordCount>0</keywordCount></qualityIndicators><title>News and Traditional Indications from Short Daily Dialysis: Different Schemes to Optimized ESF Response</title><genre><json:string>abstract</json:string></genre><host><title>Hemodialysis International</title><language><json:string>unknown</json:string></language><doi><json:string>10.1111/(ISSN)1542-4758</json:string></doi><issn><json:string>1492-7535</json:string></issn><eissn><json:string>1542-4758</json:string></eissn><publisherId><json:string>HDI</json:string></publisherId><volume>8</volume><issue>1</issue><pages><first>85</first><last>85</last><total>100</total></pages><genre><json:string>journal</json:string></genre></host><namedEntities><unitex><date><json:string>8/1/03</json:string><json:string>2/8/03</json:string><json:string>between May 2002 and September 2003</json:string><json:string>2001</json:string><json:string>1993</json:string><json:string>1971</json:string><json:string>1998</json:string><json:string>6050</json:string><json:string>1203</json:string><json:string>1999</json:string><json:string>4445</json:string><json:string>1990</json:string><json:string>2/10/03</json:string><json:string>2003</json:string><json:string>1995</json:string><json:string>2/3/03</json:string><json:string>2001 and 6/2003</json:string><json:string>1087</json:string><json:string>1117</json:string><json:string>2004</json:string><json:string>3706</json:string></date><geogName></geogName><orgName><json:string>University of Toronto</json:string><json:string>Loyola University</json:string><json:string>Department of Internal Medicine</json:string><json:string>Genpharm</json:string><json:string>Saint Michael’s Hospital, Toronto, Ontario, Canada</json:string><json:string>Michael’s Hospital, Toronto, Ontario, Canada</json:string><json:string>Department of Internal Medicine, Yonsei University College of Medicine, Seoul</json:string><json:string>Air Force</json:string><json:string>Spokane Kidney Center</json:string><json:string>Kidney Center</json:string><json:string>Washington University</json:string><json:string>Amiens University Hospital, Amiens, France</json:string><json:string>Hospital ID</json:string><json:string>Department of Nephrology, Hippokratio General Hospital, Thessaloniki, Greece</json:string><json:string>Children’s Hospital, Vancouver, BC, Canada</json:string><json:string>University of Mississippi</json:string><json:string>University Hospital of Ioannina, Greece</json:string><json:string>University of Texas Medical Branch</json:string><json:string>Kalamazoo Center for Medical Studies</json:string><json:string>Health Sciences Center</json:string><json:string>US Vascular Access Protocol</json:string><json:string>China, Hong Kong, and Canada</json:string><json:string>The Catholic University</json:string><json:string>Medical Center</json:string><json:string>Barsoum Cairo Kidney Center, Cairo, Egypt</json:string><json:string>Department of General Surgery</json:string><json:string>Lynchburg Nephrology Dialysis Inc.</json:string><json:string>Louis University</json:string><json:string>US HD</json:string><json:string>Department of Internal Medicine, National Taiwan University Hospital</json:string><json:string>Department of Orthopaedic Surgery, Osaka Police Hospital, Osaka, Japan</json:string><json:string>Division of Nephrology</json:string><json:string>Minneapolis Medical Research Foundation, Minneapolis, MN</json:string><json:string>Department of Microbiology, Cukurova University, Adana, Turkey</json:string><json:string>Society for Hemodialysis Short Daily Hemodialysis</json:string><json:string>Renal Care Center, Yokohama</json:string><json:string>University of Missouri</json:string><json:string>InCube, Inc.</json:string><json:string>Shonan Institute of Technology, Fujisawa, Kanagawa</json:string><json:string>Clinical Laboratory, Medical University Hospital</json:string><json:string>Department of Nephrology, Hippokration General Hospital, Thessaloniki, Greece</json:string><json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, South Korea</json:string><json:string>Tuchiya General Hospital, Hiroshima, Hiroshima, Japan</json:string><json:string>University of California San Francisco Medical Center, San Francisco</json:string><json:string>En Chu Kong Hospital, Taipei, Taiwan</json:string><json:string>Society for Hemodialysis Daily Online Hemodia</json:string><json:string>Jos University Teaching Hospital, Jos, Nigeria, and University of New Mexico, Albuquerque, NM</json:string><json:string>Ministry of Health</json:string><json:string>Department of Clinical Pathology, The Catholic University of Korea, Seoul, South Korea</json:string><json:string>Department of Nephrology, Papageorgiou General Hospital</json:string><json:string>Louis University Hospital, St</json:string><json:string>Renal Research Institute, New Haven, CT</json:string><json:string>Department of Nephrology</json:string><json:string>Department of Medicine, Semmelweis University, Budapest, Hungary</json:string><json:string>Dialysis Center</json:string><json:string>Department of Blood Puri</json:string><json:string>Division of Rheumatology</json:string><json:string>Department of Nephrology, Kobe General Hospital, Kobe, Japan</json:string><json:string>and US HD</json:string><json:string>Childrens Hospital, University of Texas Medical Branch, Galveston, TX</json:string><json:string>Abstracts Hemodialysis International</json:string><json:string>VA Hospital/Loyola University Medical Center, Chicago, IL</json:string><json:string>Department of Nephrology H</json:string><json:string>Division of Pediatric Nephrology</json:string><json:string>Baskent University</json:string><json:string>General Hospital, Athens, Greece</json:string><json:string>Consiglio</json:string><json:string>The Jos University</json:string><json:string>University of Texas Health Science Center, San Antonio</json:string><json:string>Department of Clinical Science, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden</json:string><json:string>University Faculty of Medicine</json:string><json:string>Virginia Commonwealth University</json:string><json:string>Medical University</json:string><json:string>Society for Hemodialysis</json:string><json:string>Shonan Institute of Technology, Fujisawa</json:string><json:string>Department of Chemical Pathology</json:string><json:string>Louisiana State University</json:string><json:string>Department of Pediatric Nephrology, University Children</json:string><json:string>Department of Nephrology, Hospital Universitario</json:string><json:string>University Hospitals of Cleveland</json:string><json:string>Division of Molecular Medicine</json:string><json:string>Department of Internal Medicine, University of Turin, Turin, Italy</json:string><json:string>Luke’s Hospital, Chester</json:string><json:string>Hospital for Sick Children, Toronto, Ontario, Canada</json:string><json:string>Department of Internal Medicine, NHIC Ilsan Hospital, Goyang, Gyeonggi, Korea</json:string><json:string>Aksys Ltd.</json:string><json:string>Kingston General Hospital, Kingston, Ontario, Canada</json:string><json:string>Department of Biochemistry</json:string><json:string>Turkey Vascular</json:string><json:string>Mercy Hospital, Kansas City, MO</json:string><json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea</json:string><json:string>Hemodialysis Hemodialysis International</json:string><json:string>Lamentin Hospital, Martinique</json:string><json:string>Taiwan HD</json:string><json:string>Institute of Medical Science, Tokai University, Isehara, Japan</json:string><json:string>Department of Nephrology, SSMC</json:string><json:string>Department of Internal Medicine and General Surgery</json:string><json:string>Department of Biostatistics, Cukurova University, Adana, Turkey</json:string><json:string>Department of Internal Medicine, Medical Research Institute, Alexandria University, Alexandria, Egypt</json:string><json:string>Michael’s Hospital Infection Control Department and Health, Canada</json:string><json:string>Central Laboratory of Immunology and Microbiology</json:string><json:string>University of Washington</json:string><json:string>Aksys Ltd</json:string><json:string>Department of Nephrology, Overton Brooks Veterans Affairs Medical Center, and Nephrology, Louisiana State University Health Sciences Center, Shreveport, LA</json:string></orgName><orgName_funder></orgName_funder><orgName_provider></orgName_provider><persName><json:string>J. Mislang</json:string><json:string>M.M. Iqbal</json:string><json:string>D.C. Jin</json:string><json:string>Kong Wu</json:string><json:string>G. Sakellariou</json:string><json:string>D. Banik</json:string><json:string>G. Piccoli</json:string><json:string>V. Laugel</json:string><json:string>R. Diamond</json:string><json:string>N. Seyrek</json:string><json:string>M. Kasahara</json:string><json:string>R. Pecoits-Filho</json:string><json:string>S.Y. Hayashi</json:string><json:string>M. Utley</json:string><json:string>R.C. Manfro</json:string><json:string>S.K. Shin</json:string><json:string>R. Garsia</json:string><json:string>C. George</json:string><json:string>J.P. Ebben</json:string><json:string>S. Sugahara</json:string><json:string>M. Sharaf-El-Din</json:string><json:string>GI Sx</json:string><json:string>T. Sakai</json:string><json:string>J. Bower</json:string><json:string>J.S. Floras</json:string><json:string>A.M. Zaki</json:string><json:string>E. Kulah</json:string><json:string>J. Torrente</json:string><json:string>Y.J. Choi</json:string><json:string>K.E. Yeates</json:string><json:string>A. Arbeiter</json:string><json:string>Research</json:string><json:string>K. Schiro-Harvey</json:string><json:string>Q. Fan</json:string><json:string>K. Weigel</json:string><json:string>J.A. Traver</json:string><json:string>F.O. Finkelstein</json:string><json:string>M.M. Nascimento</json:string><json:string>A. Petropoulou</json:string><json:string>N. Azam</json:string><json:string>L. Nagy</json:string><json:string>H. Kawanishi</json:string><json:string>I. Stanchev</json:string><json:string>U.S.A. Objective</json:string><json:string>I. Ma</json:string><json:string>C. Liaskos</json:string><json:string>S. Christopoulou</json:string><json:string>I. Kulcsar</json:string><json:string>S. White</json:string><json:string>M. Sevilla</json:string><json:string>U.S.A. Bacteremia</json:string><json:string>R.S. Lockridge</json:string><json:string>J.C.D. Baylon</json:string><json:string>D.R. Ryu</json:string><json:string>S. Paydas</json:string><json:string>J. Samik</json:string><json:string>V.U. Dreizin</json:string><json:string>C.W. Yang</json:string><json:string>D.S. Han</json:string><json:string>S. Ferenczi</json:string><json:string>D. Hobbs</json:string><json:string>L. Flynn</json:string><json:string>J. Hynes</json:string><json:string>J. Terzic</json:string><json:string>M.F. Weiss</json:string><json:string>D.S. Lirenman</json:string><json:string>E.J. Choi</json:string><json:string>V. Methods</json:string><json:string>A. Jeantet</json:string><json:string>R. Halker</json:string><json:string>S. Yang</json:string><json:string>R. Carson</json:string><json:string>S. Cetiner</json:string><json:string>V. Liakopoulos</json:string><json:string>S.J. Oh</json:string><json:string>M. Velizatova</json:string><json:string>B.A. Warady</json:string><json:string>T. Gehr</json:string><json:string>C. Bainey</json:string><json:string>Y.S. Chang</json:string><json:string>Y.O. Kim</json:string><json:string>P. Karabatakis</json:string><json:string>Y.S. Kim</json:string><json:string>L.L. Jones</json:string><json:string>D.L. Campbell</json:string><json:string>R.H. Glew</json:string><json:string>A. Takesawa</json:string><json:string>S.H. Lee</json:string><json:string>C.T. Chan</json:string><json:string>T. Drossert</json:string><json:string>E.I. Agaba</json:string><json:string>K. Sakurai</json:string><json:string>S. Blankshaen</json:string><json:string>R.A. Tzamaloukas</json:string><json:string>S. Zarogiannis</json:string><json:string>K. McPhail</json:string><json:string>S. Hadjiev</json:string><json:string>E. Weinhandl</json:string><json:string>L. Paille</json:string><json:string>A.M. Belechri</json:string><json:string>P.F. Hoyer</json:string><json:string>T.S. Ing</json:string><json:string>L. Cantey</json:string><json:string>A.J. Collins</json:string><json:string>T. Fuji</json:string><json:string>M. Kreuzer</json:string><json:string>R. Nemec</json:string><json:string>M. Philipneri</json:string><json:string>J. Szegedi</json:string><json:string>B. Young</json:string><json:string>Z.J. Twardowski</json:string><json:string>A. Papagianni</json:string><json:string>N.K. Atray</json:string><json:string>G. Barril</json:string><json:string>V. Papazov</json:string><json:string>M. Burdese</json:string><json:string>M.S. Jackson</json:string><json:string>M.Y. Hassan</json:string><json:string>M. Gellens</json:string><json:string>I. El-Esper</json:string><json:string>U.S.A. Nephrogenic</json:string><json:string>M. Jayoma</json:string><json:string>E.A. Iliescu</json:string><json:string>E. Mitsopoulos</json:string><json:string>J. Traeger</json:string><json:string>L.A. Douglas</json:string><json:string>H.A. Maiza</json:string><json:string>B. Lindholm</json:string><json:string>U.S.A. Background</json:string><json:string>M.O. Spencer</json:string><json:string>A. Kroeker</json:string><json:string>N. Herian</json:string><json:string>A.C. Yamashita</json:string><json:string>A. Livolsi</json:string><json:string>C.M. Kjellstrand</json:string><json:string>C. Li</json:string><json:string>V. Carreno</json:string><json:string>P. Hann</json:string><json:string>T. Masuda</json:string><json:string>Hemodialysis</json:string><json:string>T. Eisen</json:string><json:string>G. Maranon</json:string><json:string>The</json:string><json:string>E.W. Kang</json:string><json:string>Have</json:string><json:string>I. Quality</json:string><json:string>U. Vester</json:string><json:string>J. Tsai</json:string><json:string>F.B. Atac</json:string><json:string>P. Caro</json:string><json:string>M. Ragab</json:string><json:string>R. Galland</json:string><json:string>E. Delawari</json:string><json:string>Anecdotal</json:string><json:string>P. Erhard</json:string><json:string>I. Kiss</json:string><json:string>J.A. Miller</json:string><json:string>Y. Sato</json:string><json:string>S. Sezer</json:string><json:string>L. Haglund</json:string><json:string>C. Carmicheal</json:string><json:string>E.K. Zervou</json:string><json:string>D. Hines</json:string><json:string>A. Jones</json:string><json:string>R.Z. Ismagilov</json:string><json:string>H. Vos</json:string><json:string>F. Boitte</json:string><json:string>T. Ing</json:string><json:string>S. Chaudhury</json:string><json:string>U.S.A. Central</json:string><json:string>G. Zabioglou</json:string><json:string>S.K. Banerjee</json:string><json:string>J. Bartolome</json:string><json:string>Any Relationship</json:string><json:string>E. Gonzalez</json:string><json:string>G.B. Piccoli</json:string><json:string>O.M. Cairoli</json:string><json:string>Nephrology</json:string><json:string>M. Shenouda</json:string><json:string>R.M. Hossain</json:string><json:string>M. Fischbach</json:string><json:string>K. Larson</json:string><json:string>A. Bruchfeld</json:string><json:string>A. Yoshimoto</json:string><json:string>V. Sreenarasimhaiah</json:string><json:string>F. Tio</json:string><json:string>P. Stenvinkel</json:string><json:string>M. Imran</json:string><json:string>Y. Chen</json:string><json:string>G. Wagner</json:string><json:string>H.M. Cho</json:string><json:string>Z. Arat</json:string><json:string>S. Yamasaki</json:string><json:string>H. Okada</json:string><json:string>H.S. Chae</json:string><json:string>N. Kojcheva</json:string><json:string>G. Kyriakopoulos</json:string><json:string>M. Yoshikawa</json:string><json:string>M.D. Lee</json:string><json:string>A. Verhallen</json:string><json:string>N. Islam</json:string><json:string>M.P. Kooistra</json:string><json:string>A. Grundy</json:string><json:string>K. Ako</json:string><json:string>L. Troidle</json:string><json:string>S.L. Johnson</json:string><json:string>A. Joseph</json:string><json:string>To</json:string><json:string>J.I. Kim</json:string><json:string>U.S.A. Introduction</json:string><json:string>A.S. Azhitaeva</json:string><json:string>S.J.A.M. Stokvis</json:string><json:string>L. 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We evaluate the short daily dialysis (SDHD) efficacy in 14 patients in conventional hemodialysis (HD) (3 weekly sessions/4 h), mean age 52.1 years, range 25–75, 10 males and 4 females, and found that they needed to increase dialysis efficiency by different medical indications: in 11 cases traditional indications – 5 cases with hypertensive myocardiopathy and severe LVH (2 of them with low left ventricle ejection fraction), 2 cases with symptomatic, ischemic cardiopathy 2 patient with big body‐surface area and elevated phosphorus levels, and 2 patients by inadequate dialysis (infradialysis conditioning malnutrition status) secondary to HD with permanent catheter. In one female (25 yr old), SDHD was prescribed to improve cardiac toxicity secondary to chemotherapy for acute promyelocytic leukemia. The index resistance of ESF decreased since the first month, and the Aranesp doses decreased by more than 40%. 1 male (49 years) with nephrogenic fibrosing dermopathy showed skin lesions with osteoblastic transformation. The skin lesions were improving since the first week, obtaining a decrease of the index resistance ESF higher than 60% in the first month. 1 male with symptomatic obstructive hypertrophic myocardiopathy showed improvement of symptoms and quality of life since the first weeks, as well as echocardiograpic signs and improvement in Hb levels and decreasing dose of ESF. The schedule in all of them was 5–6 days/week sessions between 2.15 h and 3 h, depending on body‐surface area. To obtain a weekly Kt/V nearest to 4, HD sessions were realized in the hospital (7 pts) or in satellite unit (7 pts). The time remaining in this schedule was between 1 and 42 months. All the patients showed clinical improvement, subjective and objective, since the first week of start of SDHD. 3 patients could be included in Tx waiting list again. Anemia improved, decreasing index resistance of ESF. In relation with this, the time necessary to improve the response to ESF was different, showing a decrease in the first month higher than 40% in two cases dialyzing with a membrane high‐flux with pore size 100 A, appearing high Hb levels also in a polycystic patient always without ESF. We observed by analyzing the results in 12 stable patients; the patients with high‐flux dialyzers showed better response to ESF. Perhaps it could offer a better clearance of large molecules (inhibitor erythropoiesis factor and high molecular weight toxins) that participate to respond to ESF.</p><p><hi rend="bold">Conclusion: </hi> Our experience shows new indications for SDHD with very good results. 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We evaluate the short daily dialysis (SDHD) efficacy in 14 patients in conventional hemodialysis (HD) (3 weekly sessions/4 h), mean age 52.1 years, range 25–75, 10 males and 4 females, and found that they needed to increase dialysis efficiency by different medical indications: in 11 cases traditional indications – 5 cases with hypertensive myocardiopathy and severe LVH (2 of them with low left ventricle ejection fraction), 2 cases with symptomatic, ischemic cardiopathy 2 patient with big body‐surface area and elevated phosphorus levels, and 2 patients by inadequate dialysis (infradialysis conditioning malnutrition status) secondary to HD with permanent catheter. In one female (25 yr old), SDHD was prescribed to improve cardiac toxicity secondary to chemotherapy for acute promyelocytic leukemia. The index resistance of ESF decreased since the first month, and the Aranesp doses decreased by more than 40%. 1 male (49 years) with nephrogenic fibrosing dermopathy showed skin lesions with osteoblastic transformation. The skin lesions were improving since the first week, obtaining a decrease of the index resistance ESF higher than 60% in the first month. 1 male with symptomatic obstructive hypertrophic myocardiopathy showed improvement of symptoms and quality of life since the first weeks, as well as echocardiograpic signs and improvement in Hb levels and decreasing dose of ESF. The schedule in all of them was 5–6 days/week sessions between 2.15 h and 3 h, depending on body‐surface area. To obtain a weekly Kt/V nearest to 4, HD sessions were realized in the hospital (7 pts) or in satellite unit (7 pts). The time remaining in this schedule was between 1 and 42 months. All the patients showed clinical improvement, subjective and objective, since the first week of start of SDHD. 3 patients could be included in Tx waiting list again. Anemia improved, decreasing index resistance of ESF. In relation with this, the time necessary to improve the response to ESF was different, showing a decrease in the first month higher than 40% in two cases dialyzing with a membrane high‐flux with pore size 100 A, appearing high Hb levels also in a polycystic patient always without ESF. We observed by analyzing the results in 12 stable patients; the patients with high‐flux dialyzers showed better response to ESF. Perhaps it could offer a better clearance of large molecules (inhibitor erythropoiesis factor and high molecular weight toxins) that participate to respond to ESF.</p><p><b>Conclusion: </b> Our experience shows new indications for SDHD with very good results. Anemia was improved in relation with SDHD, when synthetic high‐flux membranes and high pore size were used.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>News and Traditional Indications from Short Daily Dialysis: Different Schemes to Optimized ESF Response</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>24th Annual Dialysis Conference: Abstracts</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>News and Traditional Indications from Short Daily Dialysis: Different Schemes to Optimized ESF Response</title></titleInfo><name type="personal"><namePart type="given">G.</namePart><namePart type="family">Barril</namePart><affiliation>Department of Nephrology H. U. 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Princesa</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S.</namePart><namePart type="family">Cigarran</namePart><affiliation>El Pilar FMC, Madrid, Spain.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R.</namePart><namePart type="family">Selgas</namePart><affiliation>Department of Nephrology H. U. Princesa</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="abstract" displayLabel="abstract" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-HPN7T1Q2-R">abstract</genre><originInfo><publisher>Blackwell Science Inc</publisher><place><placeTerm type="text">Oxford, UK; Malden, USA</placeTerm></place><dateIssued encoding="w3cdtf">2004-01</dateIssued><copyrightDate encoding="w3cdtf">2004</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="figures">0</extent><extent unit="tables">0</extent><extent unit="formulas">0</extent><extent unit="references">0</extent><extent unit="linksCrossRef">0</extent><extent unit="words">0</extent></physicalDescription><abstract lang="en">Interest in quotidian (daily) hemodialysis (DHD) seems to be growing. DHD improves quality of life, blood pressure control, and nutrition, and decreases the need of medications, including erythropoiesis stimulating factors (ESF). We evaluate the short daily dialysis (SDHD) efficacy in 14 patients in conventional hemodialysis (HD) (3 weekly sessions/4 h), mean age 52.1 years, range 25–75, 10 males and 4 females, and found that they needed to increase dialysis efficiency by different medical indications: in 11 cases traditional indications – 5 cases with hypertensive myocardiopathy and severe LVH (2 of them with low left ventricle ejection fraction), 2 cases with symptomatic, ischemic cardiopathy 2 patient with big body‐surface area and elevated phosphorus levels, and 2 patients by inadequate dialysis (infradialysis conditioning malnutrition status) secondary to HD with permanent catheter. In one female (25 yr old), SDHD was prescribed to improve cardiac toxicity secondary to chemotherapy for acute promyelocytic leukemia. The index resistance of ESF decreased since the first month, and the Aranesp doses decreased by more than 40%. 1 male (49 years) with nephrogenic fibrosing dermopathy showed skin lesions with osteoblastic transformation. The skin lesions were improving since the first week, obtaining a decrease of the index resistance ESF higher than 60% in the first month. 1 male with symptomatic obstructive hypertrophic myocardiopathy showed improvement of symptoms and quality of life since the first weeks, as well as echocardiograpic signs and improvement in Hb levels and decreasing dose of ESF. The schedule in all of them was 5–6 days/week sessions between 2.15 h and 3 h, depending on body‐surface area. To obtain a weekly Kt/V nearest to 4, HD sessions were realized in the hospital (7 pts) or in satellite unit (7 pts). The time remaining in this schedule was between 1 and 42 months. All the patients showed clinical improvement, subjective and objective, since the first week of start of SDHD. 3 patients could be included in Tx waiting list again. Anemia improved, decreasing index resistance of ESF. In relation with this, the time necessary to improve the response to ESF was different, showing a decrease in the first month higher than 40% in two cases dialyzing with a membrane high‐flux with pore size 100 A, appearing high Hb levels also in a polycystic patient always without ESF. We observed by analyzing the results in 12 stable patients; the patients with high‐flux dialyzers showed better response to ESF. Perhaps it could offer a better clearance of large molecules (inhibitor erythropoiesis factor and high molecular weight toxins) that participate to respond to ESF. Conclusion: Our experience shows new indications for SDHD with very good results. Anemia was improved in relation with SDHD, when synthetic high‐flux membranes and high pore size were used.</abstract><relatedItem type="host"><titleInfo><title>Hemodialysis International</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><identifier type="ISSN">1492-7535</identifier><identifier type="eISSN">1542-4758</identifier><identifier type="DOI">10.1111/(ISSN)1542-4758</identifier><identifier type="PublisherID">HDI</identifier><part><date>2004</date><detail type="volume"><caption>vol.</caption><number>8</number></detail><detail type="issue"><caption>no.</caption><number>1</number></detail><extent unit="pages"><start>85</start><end>85</end><total>100</total></extent></part></relatedItem><identifier type="istex">029A05ED3C6396849003366B88A2917BD14001DA</identifier><identifier type="ark">ark:/67375/WNG-Q7V03D3L-0</identifier><identifier type="DOI">10.1111/j.1492-7535.2004.0085r.x</identifier><identifier type="ArticleID">HDI085R</identifier><accessCondition type="use and reproduction" contentType="copyright">© Wiley. 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