The Effect of Increasing Blood Flow Rate on Dialysis Adequacy in Hemodialysis Patients with Low Kt/V
Identifieur interne : 000967 ( Istex/Corpus ); précédent : 000966; suivant : 000968The Effect of Increasing Blood Flow Rate on Dialysis Adequacy in Hemodialysis Patients with Low Kt/V
Auteurs : Y. O. Kim ; W. J. Song ; S. A. Yoon ; M. J. Shin ; H. C. Song ; Y. S. Kim ; S. Y Kim ; Y. S. Chang ; B. K. BangSource :
- Hemodialysis International [ 1492-7535 ] ; 2004-01.
Abstract
Dialysis adequacy indexed by Kt/V in hemodialysis (HD) patients is recommended as a single‐pool Kt/V of at least 1.2 per session thrice weekly. But many patients cannot achieve this adequacy target. Although dialysis time is the most important as a factor influencing Kt/V, it is difficult to prolong dialysis time in practice because of its economic impact and poor patient compliance. Objective: The aim of this study is to investigate the effect of increasing blood flow rate on dialysis adequacy in HD patients with low Kt/V. Methods: This study enrolled 36 HD patients with single‐pool Kt/V <1.2 per session thrice weekly, which was measured in dialyzer blood flow rate of 230 mL/min. We increased 15% of blood flow rate in patients <65 kg of body weight and 20% in patients >65 kg. And then we compared Kt/V and urea reduction ratio (URR) between before and after increasing blood flow rate. Results: The mean age was 48 ± 11 years (23–73 years), and the number of males was 25. Of the total patients, 24 patients had dry weight <65 kg. Mean dialysis duration was 52 ± 50 months (3–216 months). Mean Kt/V before increasing blood flow rate was 1.02 ± 0.09. It increased to 1.14 ± 0.12 after increasing blood flow rate (p < 0.001). Of the total 36 patients, 13 patients (36.1%) achieved adequacy target (Kt/V ≤ 1.2). Mean URR before increasing blood flow rate was 56.9 ± 4.0%. It also increased to 60.8 ± 4.1% (p < 0.001). Conclusion: Our data suggest that increasing blood flow rate by 15–20% of previous flow rate is effective in achieving dialysis adequacy in HD patients with low Kt/V.
Url:
DOI: 10.1111/j.1492-7535.2004.0085q.x
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Yoon</name><affiliation><mods:affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</mods:affiliation></affiliation></author><author><name sortKey="Shin, M J" sort="Shin, M J" uniqKey="Shin M" first="M. J." last="Shin">M. J. Shin</name><affiliation><mods:affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</mods:affiliation></affiliation></author><author><name sortKey="Song, H C" sort="Song, H C" uniqKey="Song H" first="H. C." last="Song">H. C. Song</name><affiliation><mods:affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</mods:affiliation></affiliation></author><author><name sortKey="Kim, Y S" sort="Kim, Y S" uniqKey="Kim Y" first="Y. S." last="Kim">Y. S. Kim</name><affiliation><mods:affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</mods:affiliation></affiliation></author><author><name sortKey="Kim, S Y" sort="Kim, S Y" uniqKey="Kim S" first="S. Y" last="Kim">S. Y Kim</name><affiliation><mods:affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</mods:affiliation></affiliation></author><author><name sortKey="Chang, Y S" sort="Chang, Y S" uniqKey="Chang Y" first="Y. S." last="Chang">Y. S. Chang</name><affiliation><mods:affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</mods:affiliation></affiliation></author><author><name sortKey="Bang, B K" sort="Bang, B K" uniqKey="Bang B" first="B. K." last="Bang">B. K. 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Kim</name><affiliation><mods:affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</mods:affiliation></affiliation></author><author><name sortKey="Song, W J" sort="Song, W J" uniqKey="Song W" first="W. J." last="Song">W. J. Song</name><affiliation><mods:affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</mods:affiliation></affiliation></author><author><name sortKey="Yoon, S A" sort="Yoon, S A" uniqKey="Yoon S" first="S. A." last="Yoon">S. A. Yoon</name><affiliation><mods:affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</mods:affiliation></affiliation></author><author><name sortKey="Shin, M J" sort="Shin, M J" uniqKey="Shin M" first="M. J." last="Shin">M. J. Shin</name><affiliation><mods:affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</mods:affiliation></affiliation></author><author><name sortKey="Song, H C" sort="Song, H C" uniqKey="Song H" first="H. C." last="Song">H. C. Song</name><affiliation><mods:affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</mods:affiliation></affiliation></author><author><name sortKey="Kim, Y S" sort="Kim, Y S" uniqKey="Kim Y" first="Y. S." last="Kim">Y. S. Kim</name><affiliation><mods:affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</mods:affiliation></affiliation></author><author><name sortKey="Kim, S Y" sort="Kim, S Y" uniqKey="Kim S" first="S. Y" last="Kim">S. Y Kim</name><affiliation><mods:affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</mods:affiliation></affiliation></author><author><name sortKey="Chang, Y S" sort="Chang, Y S" uniqKey="Chang Y" first="Y. S." last="Chang">Y. S. Chang</name><affiliation><mods:affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</mods:affiliation></affiliation></author><author><name sortKey="Bang, B K" sort="Bang, B K" uniqKey="Bang B" first="B. K." last="Bang">B. K. Bang</name><affiliation><mods:affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Hemodialysis International</title><title level="j" type="alt">HEMODIALYSIS INTERNATIONAL</title><idno type="ISSN">1492-7535</idno><idno type="eISSN">1542-4758</idno><imprint><biblScope unit="vol">8</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="85">85</biblScope><biblScope unit="page" to="85">85</biblScope><biblScope unit="page-count">100</biblScope><publisher>Blackwell Science Inc</publisher><pubPlace>Oxford, UK; Malden, USA</pubPlace><date type="published" when="2004-01">2004-01</date></imprint><idno type="ISSN">1492-7535</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1492-7535</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Dialysis adequacy indexed by Kt/V in hemodialysis (HD) patients is recommended as a single‐pool Kt/V of at least 1.2 per session thrice weekly. But many patients cannot achieve this adequacy target. Although dialysis time is the most important as a factor influencing Kt/V, it is difficult to prolong dialysis time in practice because of its economic impact and poor patient compliance. Objective: The aim of this study is to investigate the effect of increasing blood flow rate on dialysis adequacy in HD patients with low Kt/V. Methods: This study enrolled 36 HD patients with single‐pool Kt/V <1.2 per session thrice weekly, which was measured in dialyzer blood flow rate of 230 mL/min. We increased 15% of blood flow rate in patients <65 kg of body weight and 20% in patients >65 kg. And then we compared Kt/V and urea reduction ratio (URR) between before and after increasing blood flow rate. Results: The mean age was 48 ± 11 years (23–73 years), and the number of males was 25. Of the total patients, 24 patients had dry weight <65 kg. Mean dialysis duration was 52 ± 50 months (3–216 months). Mean Kt/V before increasing blood flow rate was 1.02 ± 0.09. It increased to 1.14 ± 0.12 after increasing blood flow rate (p < 0.001). Of the total 36 patients, 13 patients (36.1%) achieved adequacy target (Kt/V ≤ 1.2). Mean URR before increasing blood flow rate was 56.9 ± 4.0%. It also increased to 60.8 ± 4.1% (p < 0.001). Conclusion: Our data suggest that increasing blood flow rate by 15–20% of previous flow rate is effective in achieving dialysis adequacy in HD patients with low Kt/V.</div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>hemodialysis</json:string><json:string>international society</json:string><json:string>annual dialysis conference</json:string><json:string>renal</json:string><json:string>nephrology</json:string><json:string>fistula</json:string><json:string>hemodialysis patient</json:string><json:string>dialyzer</json:string><json:string>heparin</json:string><json:string>dialysate</json:string><json:string>datum</json:string><json:string>urea</json:string><json:string>online</json:string><json:string>venous</json:string><json:string>esrd</json:string><json:string>creatinine</json:string><json:string>hemodialysis hemodialysis 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period</json:string><json:string>radial artery wall thickness</json:string><json:string>prospective study</json:string><json:string>unsung hero</json:string><json:string>saint hospital</json:string><json:string>provincial emergency</json:string><json:string>probable case</json:string><json:string>hemodialysis unit</json:string><json:string>study period</json:string><json:string>arterial blood pressure</json:string><json:string>physical health</json:string><json:string>relative donor</json:string><json:string>tremendous improvement</json:string><json:string>significant independent predictor</json:string><json:string>individual scale</json:string><json:string>general hospital</json:string><json:string>heart failure</json:string><json:string>tesio catheter</json:string><json:string>dialysis catheter</json:string><json:string>average staff time</json:string><json:string>extracorporeal serum</json:string><json:string>urea kinetics</json:string><json:string>body size</json:string><json:string>urea mass</json:string><json:string>dialysis modality</json:string><json:string>initial flow</json:string><json:string>vascular surgeon</json:string><json:string>causative agent</json:string><json:string>precautionary measure</json:string><json:string>peer pressure</json:string><json:string>syndrome</json:string><json:string>ontario</json:string><json:string>albumin</json:string><json:string>clearance</json:string><json:string>mortality</json:string><json:string>complication</json:string><json:string>hemoglobin</json:string><json:string>diabetes</json:string><json:string>infection</json:string></teeft></keywords><author><json:item><name>Y.o. Kim</name><affiliations><json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</json:string></affiliations></json:item><json:item><name>W.j. Song</name><affiliations><json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</json:string></affiliations></json:item><json:item><name>S.a. Yoon</name><affiliations><json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</json:string></affiliations></json:item><json:item><name>M.j. Shin</name><affiliations><json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</json:string></affiliations></json:item><json:item><name>H.c. Song</name><affiliations><json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</json:string></affiliations></json:item><json:item><name>Y.s. Kim</name><affiliations><json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</json:string></affiliations></json:item><json:item><name>S.y Kim</name><affiliations><json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</json:string></affiliations></json:item><json:item><name>Y.s. Chang</name><affiliations><json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</json:string></affiliations></json:item><json:item><name>B.k. Bang</name><affiliations><json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</json:string></affiliations></json:item></author><articleId><json:string>HDI085Q</json:string></articleId><arkIstex>ark:/67375/WNG-R1MMFSSS-Z</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>abstract</json:string></originalGenre><abstract>Dialysis adequacy indexed by Kt/V in hemodialysis (HD) patients is recommended as a single‐pool Kt/V of at least 1.2 per session thrice weekly. But many patients cannot achieve this adequacy target. Although dialysis time is the most important as a factor influencing Kt/V, it is difficult to prolong dialysis time in practice because of its economic impact and poor patient compliance. Objective: The aim of this study is to investigate the effect of increasing blood flow rate on dialysis adequacy in HD patients with low Kt/V. Methods: This study enrolled 36 HD patients with single‐pool Kt/V >1.2 per session thrice weekly, which was measured in dialyzer blood flow rate of 230 mL/min. We increased 15% of blood flow rate in patients >65 kg of body weight and 20% in patients >65 kg. And then we compared Kt/V and urea reduction ratio (URR) between before and after increasing blood flow rate. Results: The mean age was 48 ± 11 years (23–73 years), and the number of males was 25. Of the total patients, 24 patients had dry weight >65 kg. Mean dialysis duration was 52 ± 50 months (3–216 months). Mean Kt/V before increasing blood flow rate was 1.02 ± 0.09. It increased to 1.14 ± 0.12 after increasing blood flow rate (p > 0.001). Of the total 36 patients, 13 patients (36.1%) achieved adequacy target (Kt/V ≤ 1.2). Mean URR before increasing blood flow rate was 56.9 ± 4.0%. It also increased to 60.8 ± 4.1% (p > 0.001). Conclusion: Our data suggest that increasing blood flow rate by 15–20% of previous flow rate is effective in achieving dialysis adequacy in HD patients with low Kt/V.</abstract><qualityIndicators><score>10</score><pdfWordCount>24342</pdfWordCount><pdfCharCount>151874</pdfCharCount><pdfVersion>1.4</pdfVersion><pdfPageCount>33</pdfPageCount><pdfPageSize>595 x 782 pts</pdfPageSize><pdfWordsPerPage>738</pdfWordsPerPage><pdfText>true</pdfText><refBibsNative>false</refBibsNative><abstractWordCount>254</abstractWordCount><abstractCharCount>1597</abstractCharCount><keywordCount>0</keywordCount></qualityIndicators><title>The Effect of Increasing Blood Flow Rate on Dialysis Adequacy in Hemodialysis Patients with Low Kt/V</title><genre><json:string>abstract</json:string></genre><host><title>Hemodialysis International</title><language><json:string>unknown</json:string></language><doi><json:string>10.1111/(ISSN)1542-4758</json:string></doi><issn><json:string>1492-7535</json:string></issn><eissn><json:string>1542-4758</json:string></eissn><publisherId><json:string>HDI</json:string></publisherId><volume>8</volume><issue>1</issue><pages><first>85</first><last>85</last><total>100</total></pages><genre><json:string>journal</json:string></genre></host><namedEntities><unitex><date><json:string>8/1/03</json:string><json:string>2/8/03</json:string><json:string>between May 2002 and September 2003</json:string><json:string>2001</json:string><json:string>1993</json:string><json:string>1971</json:string><json:string>1998</json:string><json:string>6050</json:string><json:string>1203</json:string><json:string>1999</json:string><json:string>4445</json:string><json:string>1990</json:string><json:string>2/10/03</json:string><json:string>2003</json:string><json:string>1995</json:string><json:string>2/3/03</json:string><json:string>2001 and 6/2003</json:string><json:string>1087</json:string><json:string>1117</json:string><json:string>2004</json:string><json:string>3706</json:string></date><geogName></geogName><orgName><json:string>University of Toronto</json:string><json:string>Loyola University</json:string><json:string>Department of Internal Medicine</json:string><json:string>Genpharm</json:string><json:string>Saint Michael’s Hospital, Toronto, Ontario, Canada</json:string><json:string>Michael’s Hospital, Toronto, Ontario, Canada</json:string><json:string>Department of Internal 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Center</json:string><json:string>Barsoum Cairo Kidney Center, Cairo, Egypt</json:string><json:string>Department of General Surgery</json:string><json:string>Lynchburg Nephrology Dialysis Inc.</json:string><json:string>Louis University</json:string><json:string>US HD</json:string><json:string>Department of Internal Medicine, National Taiwan University Hospital</json:string><json:string>Department of Orthopaedic Surgery, Osaka Police Hospital, Osaka, Japan</json:string><json:string>Division of Nephrology</json:string><json:string>Minneapolis Medical Research Foundation, Minneapolis, MN</json:string><json:string>Department of Microbiology, Cukurova University, Adana, Turkey</json:string><json:string>Society for Hemodialysis Short Daily Hemodialysis</json:string><json:string>Renal Care Center, Yokohama</json:string><json:string>University of Missouri</json:string><json:string>InCube, Inc.</json:string><json:string>Shonan Institute of Technology, Fujisawa, 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Hospital</json:string><json:string>Louis University Hospital, St</json:string><json:string>Renal Research Institute, New Haven, CT</json:string><json:string>Department of Nephrology</json:string><json:string>Department of Medicine, Semmelweis University, Budapest, Hungary</json:string><json:string>Dialysis Center</json:string><json:string>Department of Blood Puri</json:string><json:string>Division of Rheumatology</json:string><json:string>Department of Nephrology, Kobe General Hospital, Kobe, Japan</json:string><json:string>and US HD</json:string><json:string>Childrens Hospital, University of Texas Medical Branch, Galveston, TX</json:string><json:string>Abstracts Hemodialysis International</json:string><json:string>VA Hospital/Loyola University Medical Center, Chicago, IL</json:string><json:string>Department of Nephrology H</json:string><json:string>Division of Pediatric Nephrology</json:string><json:string>Baskent University</json:string><json:string>General Hospital, Athens, Greece</json:string><json:string>Consiglio</json:string><json:string>The Jos University</json:string><json:string>University of Texas Health Science Center, San Antonio</json:string><json:string>Department of Clinical Science, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden</json:string><json:string>University Faculty of Medicine</json:string><json:string>Virginia Commonwealth University</json:string><json:string>Medical University</json:string><json:string>Society for Hemodialysis</json:string><json:string>Shonan Institute of Technology, Fujisawa</json:string><json:string>Department of Chemical Pathology</json:string><json:string>Louisiana State University</json:string><json:string>Department of Pediatric Nephrology, University Children</json:string><json:string>Department of Nephrology, Hospital Universitario</json:string><json:string>University Hospitals of Cleveland</json:string><json:string>Division of Molecular Medicine</json:string><json:string>Department of Internal Medicine, University of Turin, Turin, Italy</json:string><json:string>Luke’s Hospital, Chester</json:string><json:string>Hospital for Sick Children, Toronto, Ontario, Canada</json:string><json:string>Department of Internal Medicine, NHIC Ilsan Hospital, Goyang, Gyeonggi, Korea</json:string><json:string>Aksys Ltd.</json:string><json:string>Kingston General Hospital, Kingston, Ontario, Canada</json:string><json:string>Department of Biochemistry</json:string><json:string>Turkey Vascular</json:string><json:string>Mercy Hospital, Kansas City, MO</json:string><json:string>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea</json:string><json:string>Hemodialysis Hemodialysis International</json:string><json:string>Lamentin Hospital, Martinique</json:string><json:string>Taiwan HD</json:string><json:string>Institute of Medical Science, Tokai University, Isehara, Japan</json:string><json:string>Department of Nephrology, 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Tio</json:string><json:string>P. Stenvinkel</json:string><json:string>M. Imran</json:string><json:string>Y. Chen</json:string><json:string>G. Wagner</json:string><json:string>H.M. Cho</json:string><json:string>Z. Arat</json:string><json:string>S. Yamasaki</json:string><json:string>H. Okada</json:string><json:string>H.S. Chae</json:string><json:string>N. Kojcheva</json:string><json:string>G. Kyriakopoulos</json:string><json:string>M. Yoshikawa</json:string><json:string>M.D. Lee</json:string><json:string>A. Verhallen</json:string><json:string>N. Islam</json:string><json:string>M.P. Kooistra</json:string><json:string>A. Grundy</json:string><json:string>K. Ako</json:string><json:string>L. Troidle</json:string><json:string>S.L. Johnson</json:string><json:string>A. Joseph</json:string><json:string>To</json:string><json:string>J.I. Kim</json:string><json:string>U.S.A. Introduction</json:string><json:string>A.S. Azhitaeva</json:string><json:string>S.J.A.M. Stokvis</json:string><json:string>L. 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type="institution">The Catholic University of Korea</orgName><address><addrLine>Seoul</addrLine><addrLine>Korea.</addrLine><country key="KR" xml:lang="en">KOREA, REPUBLIC OF</country></address></affiliation></author><author xml:id="author-0001"><persName><forename type="first">W.j.</forename><surname>Song</surname></persName><affiliation><orgName type="division">Department of Internal Medicine</orgName><orgName type="institution">The Catholic University of Korea</orgName><address><addrLine>Seoul</addrLine><addrLine>Korea.</addrLine><country key="KR" xml:lang="en">KOREA, REPUBLIC OF</country></address></affiliation></author><author xml:id="author-0002"><persName><forename type="first">S.a.</forename><surname>Yoon</surname></persName><affiliation><orgName type="division">Department of Internal Medicine</orgName><orgName type="institution">The Catholic University of Korea</orgName><address><addrLine>Seoul</addrLine><addrLine>Korea.</addrLine><country key="KR" xml:lang="en">KOREA, REPUBLIC OF</country></address></affiliation></author><author xml:id="author-0003"><persName><forename type="first">M.j.</forename><surname>Shin</surname></persName><affiliation><orgName type="division">Department of Internal Medicine</orgName><orgName type="institution">The Catholic University of Korea</orgName><address><addrLine>Seoul</addrLine><addrLine>Korea.</addrLine><country key="KR" xml:lang="en">KOREA, REPUBLIC OF</country></address></affiliation></author><author xml:id="author-0004"><persName><forename type="first">H.c.</forename><surname>Song</surname></persName><affiliation><orgName type="division">Department of Internal Medicine</orgName><orgName type="institution">The Catholic University of Korea</orgName><address><addrLine>Seoul</addrLine><addrLine>Korea.</addrLine><country key="KR" xml:lang="en">KOREA, REPUBLIC OF</country></address></affiliation></author><author xml:id="author-0005"><persName><forename type="first">Y.s.</forename><surname>Kim</surname></persName><affiliation><orgName type="division">Department of Internal Medicine</orgName><orgName type="institution">The Catholic University of Korea</orgName><address><addrLine>Seoul</addrLine><addrLine>Korea.</addrLine><country key="KR" xml:lang="en">KOREA, REPUBLIC OF</country></address></affiliation></author><author xml:id="author-0006"><persName><forename type="first">S.y</forename><surname>Kim</surname></persName><affiliation><orgName type="division">Department of Internal Medicine</orgName><orgName type="institution">The Catholic University of Korea</orgName><address><addrLine>Seoul</addrLine><addrLine>Korea.</addrLine><country key="KR" xml:lang="en">KOREA, REPUBLIC OF</country></address></affiliation></author><author xml:id="author-0007"><persName><forename type="first">Y.s.</forename><surname>Chang</surname></persName><affiliation><orgName type="division">Department of Internal Medicine</orgName><orgName type="institution">The Catholic University of Korea</orgName><address><addrLine>Seoul</addrLine><addrLine>Korea.</addrLine><country key="KR" xml:lang="en">KOREA, REPUBLIC OF</country></address></affiliation></author><author xml:id="author-0008"><persName><forename type="first">B.k.</forename><surname>Bang</surname></persName><affiliation><orgName type="division">Department of Internal Medicine</orgName><orgName type="institution">The Catholic University of Korea</orgName><address><addrLine>Seoul</addrLine><addrLine>Korea.</addrLine><country key="KR" xml:lang="en">KOREA, REPUBLIC OF</country></address></affiliation></author><idno type="istex">992BE1BB8CCF30DB90BBEFBDFE5FC13F82CC7888</idno><idno type="ark">ark:/67375/WNG-R1MMFSSS-Z</idno><idno type="DOI">10.1111/j.1492-7535.2004.0085q.x</idno><idno type="unit">HDI085Q</idno><idno type="toTypesetVersion">file:HDI.HDI085Q.pdf</idno></analytic><monogr><title level="j" type="main">Hemodialysis International</title><title level="j" type="alt">HEMODIALYSIS INTERNATIONAL</title><idno type="pISSN">1492-7535</idno><idno type="eISSN">1542-4758</idno><idno type="book-DOI">10.1111/(ISSN)1542-4758</idno><idno type="book-part-DOI">10.1111/hdi.2004.8.issue-1</idno><idno type="product">HDI</idno><idno type="publisherDivision">ST</idno><imprint><biblScope unit="vol">8</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="85">85</biblScope><biblScope unit="page" to="85">85</biblScope><biblScope unit="page-count">100</biblScope><publisher>Blackwell Science Inc</publisher><pubPlace>Oxford, UK; Malden, USA</pubPlace><date type="published" when="2004-01"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><encodingDesc><schemaRef type="ODD" url="https://xml-schema.delivery.istex.fr/tei-istex.odd"></schemaRef><appInfo><application ident="pub2tei" version="1.0.10" when="2019-12-20"><label>pub2TEI-ISTEX</label><desc>A set of style sheets for converting XML documents encoded in various scientific publisher formats into a 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And then we compared Kt/V and urea reduction ratio (URR) between before and after increasing blood flow rate.</p><p><hi rend="bold">Results: </hi> The mean age was 48 ± 11 years (23–73 years), and the number of males was 25. Of the total patients, 24 patients had dry weight <65 kg. Mean dialysis duration was 52 ± 50 months (3–216 months). Mean Kt/V before increasing blood flow rate was 1.02 ± 0.09. It increased to 1.14 ± 0.12 after increasing blood flow rate (p < 0.001). Of the total 36 patients, 13 patients (36.1%) achieved adequacy target (Kt/V ≤ 1.2). Mean URR before increasing blood flow rate was 56.9 ± 4.0%. It also increased to 60.8 ± 4.1% (p < 0.001).</p><p><hi rend="bold">Conclusion: </hi> Our data suggest that increasing blood flow rate by 15–20% of previous flow rate is effective in achieving dialysis adequacy in HD patients with low Kt/V.</p></abstract><textClass><keywords rend="tocHeading1"><term>Hemodialysis Abstracts from the 24th Annual Dialysis Conference</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc><revisionDesc><change when="2019-12-20" who="#istex" xml:id="pub2tei">formatting</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-R1MMFSSS-Z/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley component found"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Science Inc</publisherName><publisherLoc>Oxford, UK; 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But many patients cannot achieve this adequacy target. Although dialysis time is the most important as a factor influencing Kt/V, it is difficult to prolong dialysis time in practice because of its economic impact and poor patient compliance.</p><p><b>Objective: </b> The aim of this study is to investigate the effect of increasing blood flow rate on dialysis adequacy in HD patients with low Kt/V.</p><p><b>Methods: </b> This study enrolled 36 HD patients with single‐pool Kt/V <1.2 per session thrice weekly, which was measured in dialyzer blood flow rate of 230 mL/min. We increased 15% of blood flow rate in patients <65 kg of body weight and 20% in patients >65 kg. And then we compared Kt/V and urea reduction ratio (URR) between before and after increasing blood flow rate.</p><p><b>Results: </b> The mean age was 48 ± 11 years (23–73 years), and the number of males was 25. Of the total patients, 24 patients had dry weight <65 kg. Mean dialysis duration was 52 ± 50 months (3–216 months). Mean Kt/V before increasing blood flow rate was 1.02 ± 0.09. It increased to 1.14 ± 0.12 after increasing blood flow rate (p < 0.001). Of the total 36 patients, 13 patients (36.1%) achieved adequacy target (Kt/V ≤ 1.2). Mean URR before increasing blood flow rate was 56.9 ± 4.0%. It also increased to 60.8 ± 4.1% (p < 0.001).</p><p><b>Conclusion: </b> Our data suggest that increasing blood flow rate by 15–20% of previous flow rate is effective in achieving dialysis adequacy in HD patients with low Kt/V.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>The Effect of Increasing Blood Flow Rate on Dialysis Adequacy in Hemodialysis Patients with Low Kt/V</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>24th Annual Dialysis Conference: Abstracts</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>The Effect of Increasing Blood Flow Rate on Dialysis Adequacy in Hemodialysis Patients with Low Kt/V</title></titleInfo><name type="personal"><namePart type="given">Y.o.</namePart><namePart type="family">Kim</namePart><affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">W.j.</namePart><namePart type="family">Song</namePart><affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S.a.</namePart><namePart type="family">Yoon</namePart><affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.j.</namePart><namePart type="family">Shin</namePart><affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H.c.</namePart><namePart type="family">Song</namePart><affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y.s.</namePart><namePart type="family">Kim</namePart><affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S.y</namePart><namePart type="family">Kim</namePart><affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y.s.</namePart><namePart type="family">Chang</namePart><affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B.k.</namePart><namePart type="family">Bang</namePart><affiliation>Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="abstract" displayLabel="abstract" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-HPN7T1Q2-R">abstract</genre><originInfo><publisher>Blackwell Science Inc</publisher><place><placeTerm type="text">Oxford, UK; Malden, USA</placeTerm></place><dateIssued encoding="w3cdtf">2004-01</dateIssued><copyrightDate encoding="w3cdtf">2004</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="figures">0</extent><extent unit="tables">0</extent><extent unit="formulas">0</extent><extent unit="references">0</extent><extent unit="linksCrossRef">0</extent><extent unit="words">0</extent></physicalDescription><abstract lang="en">Dialysis adequacy indexed by Kt/V in hemodialysis (HD) patients is recommended as a single‐pool Kt/V of at least 1.2 per session thrice weekly. But many patients cannot achieve this adequacy target. Although dialysis time is the most important as a factor influencing Kt/V, it is difficult to prolong dialysis time in practice because of its economic impact and poor patient compliance. Objective: The aim of this study is to investigate the effect of increasing blood flow rate on dialysis adequacy in HD patients with low Kt/V. Methods: This study enrolled 36 HD patients with single‐pool Kt/V <1.2 per session thrice weekly, which was measured in dialyzer blood flow rate of 230 mL/min. We increased 15% of blood flow rate in patients <65 kg of body weight and 20% in patients >65 kg. And then we compared Kt/V and urea reduction ratio (URR) between before and after increasing blood flow rate. Results: The mean age was 48 ± 11 years (23–73 years), and the number of males was 25. Of the total patients, 24 patients had dry weight <65 kg. Mean dialysis duration was 52 ± 50 months (3–216 months). Mean Kt/V before increasing blood flow rate was 1.02 ± 0.09. It increased to 1.14 ± 0.12 after increasing blood flow rate (p < 0.001). Of the total 36 patients, 13 patients (36.1%) achieved adequacy target (Kt/V ≤ 1.2). Mean URR before increasing blood flow rate was 56.9 ± 4.0%. It also increased to 60.8 ± 4.1% (p < 0.001). Conclusion: Our data suggest that increasing blood flow rate by 15–20% of previous flow rate is effective in achieving dialysis adequacy in HD patients with low Kt/V.</abstract><relatedItem type="host"><titleInfo><title>Hemodialysis International</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><identifier type="ISSN">1492-7535</identifier><identifier type="eISSN">1542-4758</identifier><identifier type="DOI">10.1111/(ISSN)1542-4758</identifier><identifier type="PublisherID">HDI</identifier><part><date>2004</date><detail type="volume"><caption>vol.</caption><number>8</number></detail><detail type="issue"><caption>no.</caption><number>1</number></detail><extent unit="pages"><start>85</start><end>85</end><total>100</total></extent></part></relatedItem><identifier type="istex">992BE1BB8CCF30DB90BBEFBDFE5FC13F82CC7888</identifier><identifier type="ark">ark:/67375/WNG-R1MMFSSS-Z</identifier><identifier type="DOI">10.1111/j.1492-7535.2004.0085q.x</identifier><identifier type="ArticleID">HDI085Q</identifier><accessCondition type="use and reproduction" contentType="copyright">© Wiley. All rights reserved.</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-L0C46X92-X">wiley</recordContentSource><recordOrigin>Converted from (version ) to MODS version 3.6.</recordOrigin><recordCreationDate encoding="w3cdtf">2019-11-14</recordCreationDate></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-R1MMFSSS-Z/record.json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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