Isotype-specific antibody responses to bovine herpesvirus 1 in sera and mucosal secretions of calves after experimental reinfection and after reactivation
Identifieur interne : 000548 ( Istex/Corpus ); précédent : 000547; suivant : 000549Isotype-specific antibody responses to bovine herpesvirus 1 in sera and mucosal secretions of calves after experimental reinfection and after reactivation
Auteurs : J. Madic ; J. Magdalena ; J. Quak ; J. T. Van OirschotSource :
- Veterinary Immunology and Immunopathology [ 0165-2427 ] ; 1995.
English descriptors
- Teeft :
- Antibody, Antibody response, Antibody responses, Antibody titres, Bhvl, Calf, Control calves, Corticosteroid, Corticosteroid treatment, Excretion, First detection, Genital, Genital secretions, Higher increase, Igg2, Igg2 antibodies, Iggl, Immunology, Immunopathology, Iowa strain, Madic, Mucosal, Mucosal secretions, Nasal, Nasal secretions, Ocular, Ocular secretions, Primary infection, Reactivation, Reinfected, Reinfected calves, Reinfection, Secretion, Serum iggl, Titre, Veterinary immunology, Virus excretion.
Abstract
Abstract: Isotype-specific antibody responses to bovine herpesvirus 1 (BHV1) were measured in sera, nasal, ocular and genital secretions of calves that were reinfected with BHV1 and 6 weeks later treated with corticosteroids to reactivate putative latent virus. After reinfection and after reactivation, no BHV1-specific IgM antibody response was detected. The serum IgA response was only transiently detectable after reinfection and again appeared rapidly after reactivation in most calves. Most calves showed an increase in nasal and ocular IgA titres after reinfection and reactivation; some calves also had IgA antibodies in genital secretions. A salient finding was that after reinfection and reactivation more calves showed a serum IgA response than virus shedding or an increase in serum IgG1 or IgG2 titres. This suggests that the serum IgA response would be the most sensitive indicator to detect BHV1 reinfection and reactivation. No correlation was found between nasal IgA titre at the time of reinfection or corticosteroid treatment and the period of virus shedding, suggesting that nasal IgA does not play a major role in protection against reinfection with BHV1.
Url:
DOI: 10.1016/0165-2427(94)05379-7
Links to Exploration step
ISTEX:F01EF63AD069D1D99A80769C7E86D135D5710551Le document en format XML
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Quak</name><affiliation><mods:affiliation>Institute for Animal Science and Health, Department of Bovine Virology, PO Box 65, 8200 AB Lelystad, Netherlands</mods:affiliation></affiliation></author><author><name sortKey="Van Oirschot, J T" sort="Van Oirschot, J T" uniqKey="Van Oirschot J" first="J. T." last="Van Oirschot">J. T. 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Madic</name><affiliation><mods:affiliation>Institute for Animal Science and Health, Department of Bovine Virology, PO Box 65, 8200 AB Lelystad, Netherlands</mods:affiliation></affiliation></author><author><name sortKey="Magdalena, J" sort="Magdalena, J" uniqKey="Magdalena J" first="J." last="Magdalena">J. Magdalena</name><affiliation><mods:affiliation>Institute for Animal Science and Health, Department of Bovine Virology, PO Box 65, 8200 AB Lelystad, Netherlands</mods:affiliation></affiliation></author><author><name sortKey="Quak, J" sort="Quak, J" uniqKey="Quak J" first="J." last="Quak">J. Quak</name><affiliation><mods:affiliation>Institute for Animal Science and Health, Department of Bovine Virology, PO Box 65, 8200 AB Lelystad, Netherlands</mods:affiliation></affiliation></author><author><name sortKey="Van Oirschot, J T" sort="Van Oirschot, J T" uniqKey="Van Oirschot J" first="J. T." last="Van Oirschot">J. T. Van Oirschot</name><affiliation><mods:affiliation>Institute for Animal Science and Health, Department of Bovine Virology, PO Box 65, 8200 AB Lelystad, Netherlands</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Veterinary Immunology and Immunopathology</title><title level="j" type="abbrev">VETIMM</title><idno type="ISSN">0165-2427</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1995">1995</date><biblScope unit="volume">47</biblScope><biblScope unit="issue">1–2</biblScope><biblScope unit="page" from="81">81</biblScope><biblScope unit="page" to="92">92</biblScope></imprint><idno type="ISSN">0165-2427</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0165-2427</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Antibody</term><term>Antibody response</term><term>Antibody responses</term><term>Antibody titres</term><term>Bhvl</term><term>Calf</term><term>Control calves</term><term>Corticosteroid</term><term>Corticosteroid treatment</term><term>Excretion</term><term>First detection</term><term>Genital</term><term>Genital secretions</term><term>Higher increase</term><term>Igg2</term><term>Igg2 antibodies</term><term>Iggl</term><term>Immunology</term><term>Immunopathology</term><term>Iowa strain</term><term>Madic</term><term>Mucosal</term><term>Mucosal secretions</term><term>Nasal</term><term>Nasal secretions</term><term>Ocular</term><term>Ocular secretions</term><term>Primary infection</term><term>Reactivation</term><term>Reinfected</term><term>Reinfected calves</term><term>Reinfection</term><term>Secretion</term><term>Serum iggl</term><term>Titre</term><term>Veterinary immunology</term><term>Virus excretion</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Isotype-specific antibody responses to bovine herpesvirus 1 (BHV1) were measured in sera, nasal, ocular and genital secretions of calves that were reinfected with BHV1 and 6 weeks later treated with corticosteroids to reactivate putative latent virus. After reinfection and after reactivation, no BHV1-specific IgM antibody response was detected. The serum IgA response was only transiently detectable after reinfection and again appeared rapidly after reactivation in most calves. Most calves showed an increase in nasal and ocular IgA titres after reinfection and reactivation; some calves also had IgA antibodies in genital secretions. A salient finding was that after reinfection and reactivation more calves showed a serum IgA response than virus shedding or an increase in serum IgG1 or IgG2 titres. This suggests that the serum IgA response would be the most sensitive indicator to detect BHV1 reinfection and reactivation. No correlation was found between nasal IgA titre at the time of reinfection or corticosteroid treatment and the period of virus shedding, suggesting that nasal IgA does not play a major role in protection against reinfection with BHV1.</div></front></TEI><istex><corpusName>elsevier</corpusName><keywords><teeft><json:string>reinfection</json:string><json:string>corticosteroid</json:string><json:string>bhvl</json:string><json:string>corticosteroid treatment</json:string><json:string>reactivation</json:string><json:string>igg2</json:string><json:string>iggl</json:string><json:string>ocular secretions</json:string><json:string>reinfected</json:string><json:string>madic</json:string><json:string>genital</json:string><json:string>genital secretions</json:string><json:string>nasal secretions</json:string><json:string>antibody response</json:string><json:string>antibody responses</json:string><json:string>immunology</json:string><json:string>veterinary immunology</json:string><json:string>immunopathology</json:string><json:string>mucosal</json:string><json:string>nasal</json:string><json:string>first detection</json:string><json:string>reinfected calves</json:string><json:string>ocular</json:string><json:string>secretion</json:string><json:string>control calves</json:string><json:string>excretion</json:string><json:string>iowa strain</json:string><json:string>mucosal secretions</json:string><json:string>igg2 antibodies</json:string><json:string>higher increase</json:string><json:string>virus excretion</json:string><json:string>titre</json:string><json:string>primary infection</json:string><json:string>serum iggl</json:string><json:string>antibody titres</json:string><json:string>antibody</json:string><json:string>calf</json:string></teeft></keywords><author><json:item><name>J. Madic</name><affiliations><json:string>Institute for Animal Science and Health, Department of Bovine Virology, PO Box 65, 8200 AB Lelystad, Netherlands</json:string></affiliations></json:item><json:item><name>J. Magdalena</name><affiliations><json:string>Institute for Animal Science and Health, Department of Bovine Virology, PO Box 65, 8200 AB Lelystad, Netherlands</json:string></affiliations></json:item><json:item><name>J. Quak</name><affiliations><json:string>Institute for Animal Science and Health, Department of Bovine Virology, PO Box 65, 8200 AB Lelystad, Netherlands</json:string></affiliations></json:item><json:item><name>J.T. van Oirschot</name><affiliations><json:string>Institute for Animal Science and Health, Department of Bovine Virology, PO Box 65, 8200 AB Lelystad, Netherlands</json:string></affiliations></json:item></author><arkIstex>ark:/67375/6H6-VLRJMQG5-T</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>Full-length article</json:string></originalGenre><abstract>Abstract: Isotype-specific antibody responses to bovine herpesvirus 1 (BHV1) were measured in sera, nasal, ocular and genital secretions of calves that were reinfected with BHV1 and 6 weeks later treated with corticosteroids to reactivate putative latent virus. After reinfection and after reactivation, no BHV1-specific IgM antibody response was detected. The serum IgA response was only transiently detectable after reinfection and again appeared rapidly after reactivation in most calves. Most calves showed an increase in nasal and ocular IgA titres after reinfection and reactivation; some calves also had IgA antibodies in genital secretions. A salient finding was that after reinfection and reactivation more calves showed a serum IgA response than virus shedding or an increase in serum IgG1 or IgG2 titres. This suggests that the serum IgA response would be the most sensitive indicator to detect BHV1 reinfection and reactivation. 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Quak</json:string><json:string>In</json:string><json:string>J.M. Miller</json:string><json:string>T. van Oirschot</json:string><json:string>J. Magdalena</json:string><json:string>H. Paal</json:string><json:string>K. Weerdmeester</json:string></persName><placeName><json:string>Germany</json:string><json:string>UK</json:string><json:string>Mannheim</json:string></placeName><ref_url></ref_url><ref_bibl><json:string>Osorio et al., 1989</json:string><json:string>J. Madic et al.</json:string><json:string>Pastoret et al., 1979</json:string><json:string>Guy and Potgieter ( 1985a)</json:string><json:string>Rodak et al., 1983</json:string><json:string>Osorio et al. ( 1989)</json:string><json:string>Madic et al., 1995</json:string><json:string>Heckert et al., 1991</json:string><json:string>Guy and Potgieter, 1985a,b</json:string><json:string>Guy and Potgieter, 1985b</json:string><json:string>Tedder et al.</json:string><json:string>Edwards et al.</json:string><json:string>Edwards et al., 1991</json:string><json:string>Van Loon et al., 1981</json:string><json:string>Kimman et al., 1987</json:string><json:string>Kaashoek et al., 1994</json:string><json:string>Rodak et al. 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After reinfection and after reactivation, no BHV1-specific IgM antibody response was detected. The serum IgA response was only transiently detectable after reinfection and again appeared rapidly after reactivation in most calves. Most calves showed an increase in nasal and ocular IgA titres after reinfection and reactivation; some calves also had IgA antibodies in genital secretions. A salient finding was that after reinfection and reactivation more calves showed a serum IgA response than virus shedding or an increase in serum IgG1 or IgG2 titres. This suggests that the serum IgA response would be the most sensitive indicator to detect BHV1 reinfection and reactivation. No correlation was found between nasal IgA titre at the time of reinfection or corticosteroid treatment and the period of virus shedding, suggesting that nasal IgA does not play a major role in protection against reinfection with BHV1.</p></abstract></profileDesc><revisionDesc><change when="1995">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/6H6-VLRJMQG5-T/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier, elements deleted: tail"><istex:xmlDeclaration>version="1.0" encoding="utf-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 4.5.2//EN//XML" URI="art452.dtd" name="istex:docType"></istex:docType><istex:document><converted-article version="4.5.2" docsubtype="fla"><item-info><jid>VETIMM</jid><aid>94053797</aid><ce:pii>0165-2427(94)05379-7</ce:pii><ce:doi>10.1016/0165-2427(94)05379-7</ce:doi><ce:copyright type="unknown" year="1995"></ce:copyright></item-info><head><ce:title>Isotype-specific antibody responses to bovine herpesvirus 1 in sera and mucosal secretions of calves after experimental reinfection and after reactivation</ce:title><ce:author-group><ce:author><ce:given-name>J.</ce:given-name><ce:surname>Madic</ce:surname><ce:cross-ref refid="FN1"><ce:sup>1</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>J.</ce:given-name><ce:surname>Magdalena</ce:surname><ce:cross-ref refid="FN2"><ce:sup>2</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>J.</ce:given-name><ce:surname>Quak</ce:surname></ce:author><ce:author><ce:given-name>J.T.</ce:given-name><ce:surname>van Oirschot</ce:surname><ce:cross-ref refid="COR1"><ce:sup>∗</ce:sup></ce:cross-ref></ce:author><ce:affiliation><ce:textfn>Institute for Animal Science and Health, Department of Bovine Virology, PO Box 65, 8200 AB Lelystad, Netherlands</ce:textfn></ce:affiliation><ce:correspondence id="COR1"><ce:label>∗</ce:label><ce:text>Corresponding author.</ce:text></ce:correspondence><ce:footnote id="FN1"><ce:label>1</ce:label><ce:note-para>Present address: Department of Microbiology and Infectious Diseases, Veterinary Faculty, University of Zagreb, 41001 Zagreb, Heinzelova 55, P.O.B. 190, Croatia.</ce:note-para></ce:footnote><ce:footnote id="FN2"><ce:label>2</ce:label><ce:note-para>Present address: Institut de Chimie B6, Université de Liège, Sart Tilman, B-4000 Liege, Belgium.</ce:note-para></ce:footnote></ce:author-group><ce:date-accepted day="12" month="8" year="1994"></ce:date-accepted><ce:abstract><ce:section-title>Abstract</ce:section-title><ce:abstract-sec><ce:simple-para>Isotype-specific antibody responses to bovine herpesvirus 1 (BHV1) were measured in sera, nasal, ocular and genital secretions of calves that were reinfected with BHV1 and 6 weeks later treated with corticosteroids to reactivate putative latent virus. After reinfection and after reactivation, no BHV1-specific IgM antibody response was detected. The serum IgA response was only transiently detectable after reinfection and again appeared rapidly after reactivation in most calves. Most calves showed an increase in nasal and ocular IgA titres after reinfection and reactivation; some calves also had IgA antibodies in genital secretions. A salient finding was that after reinfection and reactivation more calves showed a serum IgA response than virus shedding or an increase in serum IgG1 or IgG2 titres. This suggests that the serum IgA response would be the most sensitive indicator to detect BHV1 reinfection and reactivation. No correlation was found between nasal IgA titre at the time of reinfection or corticosteroid treatment and the period of virus shedding, suggesting that nasal IgA does not play a major role in protection against reinfection with BHV1.</ce:simple-para></ce:abstract-sec></ce:abstract></head></converted-article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo><title>Isotype-specific antibody responses to bovine herpesvirus 1 in sera and mucosal secretions of calves after experimental reinfection and after reactivation</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Isotype-specific antibody responses to bovine herpesvirus 1 in sera and mucosal secretions of calves after experimental reinfection and after reactivation</title></titleInfo><name type="personal"><namePart type="given">J.</namePart><namePart type="family">Madic</namePart><affiliation>Institute for Animal Science and Health, Department of Bovine Virology, PO Box 65, 8200 AB Lelystad, Netherlands</affiliation><description>Present address: Department of Microbiology and Infectious Diseases, Veterinary Faculty, University of Zagreb, 41001 Zagreb, Heinzelova 55, P.O.B. 190, Croatia.</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J.</namePart><namePart type="family">Magdalena</namePart><affiliation>Institute for Animal Science and Health, Department of Bovine Virology, PO Box 65, 8200 AB Lelystad, Netherlands</affiliation><description>Present address: Institut de Chimie B6, Université de Liège, Sart Tilman, B-4000 Liege, Belgium.</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J.</namePart><namePart type="family">Quak</namePart><affiliation>Institute for Animal Science and Health, Department of Bovine Virology, PO Box 65, 8200 AB Lelystad, Netherlands</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J.T.</namePart><namePart type="family">van Oirschot</namePart><affiliation>Institute for Animal Science and Health, Department of Bovine Virology, PO Box 65, 8200 AB Lelystad, Netherlands</affiliation><description>Corresponding author.</description><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1995</dateIssued><copyrightDate encoding="w3cdtf">1995</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><abstract lang="en">Abstract: Isotype-specific antibody responses to bovine herpesvirus 1 (BHV1) were measured in sera, nasal, ocular and genital secretions of calves that were reinfected with BHV1 and 6 weeks later treated with corticosteroids to reactivate putative latent virus. After reinfection and after reactivation, no BHV1-specific IgM antibody response was detected. The serum IgA response was only transiently detectable after reinfection and again appeared rapidly after reactivation in most calves. Most calves showed an increase in nasal and ocular IgA titres after reinfection and reactivation; some calves also had IgA antibodies in genital secretions. A salient finding was that after reinfection and reactivation more calves showed a serum IgA response than virus shedding or an increase in serum IgG1 or IgG2 titres. This suggests that the serum IgA response would be the most sensitive indicator to detect BHV1 reinfection and reactivation. No correlation was found between nasal IgA titre at the time of reinfection or corticosteroid treatment and the period of virus shedding, suggesting that nasal IgA does not play a major role in protection against reinfection with BHV1.</abstract><relatedItem type="host"><titleInfo><title>Veterinary Immunology and Immunopathology</title></titleInfo><titleInfo type="abbreviated"><title>VETIMM</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1995</dateIssued></originInfo><identifier type="ISSN">0165-2427</identifier><identifier type="PII">S0165-2427(00)X0013-X</identifier><part><date>1995</date><detail type="volume"><number>47</number><caption>vol.</caption></detail><detail type="issue"><number>1–2</number><caption>no.</caption></detail><extent unit="issue-pages"><start>1</start><end>186</end></extent><extent unit="pages"><start>81</start><end>92</end></extent></part></relatedItem><identifier type="istex">F01EF63AD069D1D99A80769C7E86D135D5710551</identifier><identifier type="ark">ark:/67375/6H6-VLRJMQG5-T</identifier><identifier type="DOI">10.1016/0165-2427(94)05379-7</identifier><identifier type="PII">0165-2427(94)05379-7</identifier><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-HKKZVM7B-M">elsevier</recordContentSource></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/ark:/67375/6H6-VLRJMQG5-T/record.json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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