CovidSeniorV1, Main, Exploration, bibRecord, 000669

Developing a COVID-19 mortality risk prediction model when individual-level data are not available.

Identifieur interne : 000669 ( Main/Exploration ); précédent : 000668; suivant : 000670

Developing a COVID-19 mortality risk prediction model when individual-level data are not available.

Auteurs : Noam Barda [Israël] ; Dan Riesel [Israël] ; Amichay Akriv [Israël] ; Joseph Levy [Israël] ; Uriah Finkel [Israël] ; Gal Yona [Israël] ; Daniel Greenfeld [Israël] ; Shimon Sheiba [Israël] ; Jonathan Somer [Israël] ; Eitan Bachmat [Israël] ; Guy N. Rothblum [Israël] ; Uri Shalit [Israël] ; Doron Netzer [Israël] ; Ran Balicer [Israël] ; Noa Dagan [Israël]

Source :

Nature communications [ 2041-1723 ] ; 2020.

RBID : pubmed:32895375

Descripteurs français

KwdFr :
- Adolescent (MeSH), Adulte (MeSH), Adulte d'âge moyen (MeSH), Betacoronavirus (isolement et purification), Courbe ROC (MeSH), Enfant (MeSH), Facteurs de risque (MeSH), Femelle (MeSH), Humains (MeSH), Infections à coronavirus (mortalité), Infections à coronavirus (virologie), Israël (épidémiologie), Jeune adulte (MeSH), Modèles statistiques (MeSH), Mâle (MeSH), Pandémies (MeSH), Pneumopathie virale (mortalité), Pneumopathie virale (virologie), Prévision (MeSH), Sujet âgé (MeSH), Sujet âgé de 80 ans ou plus (MeSH), Études de cohortes (MeSH), Études rétrospectives (MeSH).
MESH :
- isolement et purification : Betacoronavirus.
- mortalité : Infections à coronavirus, Pneumopathie virale.
- virologie : Infections à coronavirus, Pneumopathie virale.
- épidémiologie : Israël.
- Adolescent, Adulte, Adulte d'âge moyen, Courbe ROC, Enfant, Facteurs de risque, Femelle, Humains, Jeune adulte, Modèles statistiques, Mâle, Pandémies, Prévision, Sujet âgé, Sujet âgé de 80 ans ou plus, Études de cohortes, Études rétrospectives.
Wicri :
- geographic : Israël.

English descriptors

KwdEn :
- Adolescent (MeSH), Adult (MeSH), Aged (MeSH), Aged, 80 and over (MeSH), Betacoronavirus (isolation & purification), Child (MeSH), Cohort Studies (MeSH), Coronavirus Infections (mortality), Coronavirus Infections (virology), Female (MeSH), Forecasting (MeSH), Humans (MeSH), Israel (epidemiology), Male (MeSH), Middle Aged (MeSH), Models, Statistical (MeSH), Pandemics (MeSH), Pneumonia, Viral (mortality), Pneumonia, Viral (virology), ROC Curve (MeSH), Retrospective Studies (MeSH), Risk Factors (MeSH), Young Adult (MeSH).
MESH :
- geographic , epidemiology : Israel.
- isolation & purification : Betacoronavirus.
- mortality : Coronavirus Infections, Pneumonia, Viral.
- virology : Coronavirus Infections, Pneumonia, Viral.
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Cohort Studies, Female, Forecasting, Humans, Male, Middle Aged, Models, Statistical, Pandemics, ROC Curve, Retrospective Studies, Risk Factors, Young Adult.

Abstract

At the COVID-19 pandemic onset, when individual-level data of COVID-19 patients were not yet available, there was already a need for risk predictors to support prevention and treatment decisions. Here, we report a hybrid strategy to create such a predictor, combining the development of a baseline severe respiratory infection risk predictor and a post-processing method to calibrate the predictions to reported COVID-19 case-fatality rates. With the accumulation of a COVID-19 patient cohort, this predictor is validated to have good discrimination (area under the receiver-operating characteristics curve of 0.943) and calibration (markedly improved compared to that of the baseline predictor). At a 5% risk threshold, 15% of patients are marked as high-risk, achieving a sensitivity of 88%. We thus demonstrate that even at the onset of a pandemic, shrouded in epidemiologic fog of war, it is possible to provide a useful risk predictor, now widely used in a large healthcare organization.

DOI: 10.1038/s41467-020-18297-9
PubMed: 32895375
PubMed Central: PMC7477233

Affiliations:

Israël

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000319
to stream Main, to step Curation: 000319

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Developing a COVID-19 mortality risk prediction model when individual-level data are not available.</title>
<author><name sortKey="Barda, Noam" sort="Barda, Noam" uniqKey="Barda N" first="Noam" last="Barda">Noam Barda</name>
<affiliation wicri:level="1"><nlm:affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan</wicri:regionArea>
<wicri:noRegion>Ramat-Gan</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>School of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>School of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva</wicri:regionArea>
<wicri:noRegion>Be'er Sheva</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>Department of Computer Science, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Department of Computer Science, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva</wicri:regionArea>
<wicri:noRegion>Be'er Sheva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Riesel, Dan" sort="Riesel, Dan" uniqKey="Riesel D" first="Dan" last="Riesel">Dan Riesel</name>
<affiliation wicri:level="1"><nlm:affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan</wicri:regionArea>
<wicri:noRegion>Ramat-Gan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Akriv, Amichay" sort="Akriv, Amichay" uniqKey="Akriv A" first="Amichay" last="Akriv">Amichay Akriv</name>
<affiliation wicri:level="1"><nlm:affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan</wicri:regionArea>
<wicri:noRegion>Ramat-Gan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Levy, Joseph" sort="Levy, Joseph" uniqKey="Levy J" first="Joseph" last="Levy">Joseph Levy</name>
<affiliation wicri:level="1"><nlm:affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan</wicri:regionArea>
<wicri:noRegion>Ramat-Gan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Finkel, Uriah" sort="Finkel, Uriah" uniqKey="Finkel U" first="Uriah" last="Finkel">Uriah Finkel</name>
<affiliation wicri:level="1"><nlm:affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan</wicri:regionArea>
<wicri:noRegion>Ramat-Gan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Yona, Gal" sort="Yona, Gal" uniqKey="Yona G" first="Gal" last="Yona">Gal Yona</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Herzl 234, Rehovot, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Herzl 234, Rehovot</wicri:regionArea>
<wicri:noRegion>Rehovot</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Greenfeld, Daniel" sort="Greenfeld, Daniel" uniqKey="Greenfeld D" first="Daniel" last="Greenfeld">Daniel Greenfeld</name>
<affiliation wicri:level="1"><nlm:affiliation>Faculty of Industrial Engineering and Management, Technion University, Haifa, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Faculty of Industrial Engineering and Management, Technion University, Haifa</wicri:regionArea>
<wicri:noRegion>Haifa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sheiba, Shimon" sort="Sheiba, Shimon" uniqKey="Sheiba S" first="Shimon" last="Sheiba">Shimon Sheiba</name>
<affiliation wicri:level="1"><nlm:affiliation>Faculty of Industrial Engineering and Management, Technion University, Haifa, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Faculty of Industrial Engineering and Management, Technion University, Haifa</wicri:regionArea>
<wicri:noRegion>Haifa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Somer, Jonathan" sort="Somer, Jonathan" uniqKey="Somer J" first="Jonathan" last="Somer">Jonathan Somer</name>
<affiliation wicri:level="1"><nlm:affiliation>Faculty of Industrial Engineering and Management, Technion University, Haifa, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Faculty of Industrial Engineering and Management, Technion University, Haifa</wicri:regionArea>
<wicri:noRegion>Haifa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bachmat, Eitan" sort="Bachmat, Eitan" uniqKey="Bachmat E" first="Eitan" last="Bachmat">Eitan Bachmat</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Computer Science, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Department of Computer Science, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva</wicri:regionArea>
<wicri:noRegion>Be'er Sheva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rothblum, Guy N" sort="Rothblum, Guy N" uniqKey="Rothblum G" first="Guy N" last="Rothblum">Guy N. Rothblum</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Herzl 234, Rehovot, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Herzl 234, Rehovot</wicri:regionArea>
<wicri:noRegion>Rehovot</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shalit, Uri" sort="Shalit, Uri" uniqKey="Shalit U" first="Uri" last="Shalit">Uri Shalit</name>
<affiliation wicri:level="1"><nlm:affiliation>Faculty of Industrial Engineering and Management, Technion University, Haifa, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Faculty of Industrial Engineering and Management, Technion University, Haifa</wicri:regionArea>
<wicri:noRegion>Haifa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Netzer, Doron" sort="Netzer, Doron" uniqKey="Netzer D" first="Doron" last="Netzer">Doron Netzer</name>
<affiliation wicri:level="1"><nlm:affiliation>Community Medical Services Division, Clalit Health Services, Arlozorov 101, Tel Aviv, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Community Medical Services Division, Clalit Health Services, Arlozorov 101, Tel Aviv</wicri:regionArea>
<wicri:noRegion>Tel Aviv</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Balicer, Ran" sort="Balicer, Ran" uniqKey="Balicer R" first="Ran" last="Balicer">Ran Balicer</name>
<affiliation wicri:level="1"><nlm:affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan</wicri:regionArea>
<wicri:noRegion>Ramat-Gan</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>School of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>School of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva</wicri:regionArea>
<wicri:noRegion>Be'er Sheva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Dagan, Noa" sort="Dagan, Noa" uniqKey="Dagan N" first="Noa" last="Dagan">Noa Dagan</name>
<affiliation wicri:level="1"><nlm:affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel. noada@clalit.org.il.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan</wicri:regionArea>
<wicri:noRegion>Ramat-Gan</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>School of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva, Israel. noada@clalit.org.il.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>School of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva</wicri:regionArea>
<wicri:noRegion>Be'er Sheva</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>Department of Computer Science, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva, Israel. noada@clalit.org.il.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Department of Computer Science, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva</wicri:regionArea>
<wicri:noRegion>Be'er Sheva</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2020">2020</date>
<idno type="RBID">pubmed:32895375</idno>
<idno type="pmid">32895375</idno>
<idno type="doi">10.1038/s41467-020-18297-9</idno>
<idno type="pmc">PMC7477233</idno>
<idno type="wicri:Area/Main/Corpus">000319</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000319</idno>
<idno type="wicri:Area/Main/Curation">000319</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000319</idno>
<idno type="wicri:Area/Main/Exploration">000319</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Developing a COVID-19 mortality risk prediction model when individual-level data are not available.</title>
<author><name sortKey="Barda, Noam" sort="Barda, Noam" uniqKey="Barda N" first="Noam" last="Barda">Noam Barda</name>
<affiliation wicri:level="1"><nlm:affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan</wicri:regionArea>
<wicri:noRegion>Ramat-Gan</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>School of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>School of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva</wicri:regionArea>
<wicri:noRegion>Be'er Sheva</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>Department of Computer Science, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Department of Computer Science, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva</wicri:regionArea>
<wicri:noRegion>Be'er Sheva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Riesel, Dan" sort="Riesel, Dan" uniqKey="Riesel D" first="Dan" last="Riesel">Dan Riesel</name>
<affiliation wicri:level="1"><nlm:affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan</wicri:regionArea>
<wicri:noRegion>Ramat-Gan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Akriv, Amichay" sort="Akriv, Amichay" uniqKey="Akriv A" first="Amichay" last="Akriv">Amichay Akriv</name>
<affiliation wicri:level="1"><nlm:affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan</wicri:regionArea>
<wicri:noRegion>Ramat-Gan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Levy, Joseph" sort="Levy, Joseph" uniqKey="Levy J" first="Joseph" last="Levy">Joseph Levy</name>
<affiliation wicri:level="1"><nlm:affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan</wicri:regionArea>
<wicri:noRegion>Ramat-Gan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Finkel, Uriah" sort="Finkel, Uriah" uniqKey="Finkel U" first="Uriah" last="Finkel">Uriah Finkel</name>
<affiliation wicri:level="1"><nlm:affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan</wicri:regionArea>
<wicri:noRegion>Ramat-Gan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Yona, Gal" sort="Yona, Gal" uniqKey="Yona G" first="Gal" last="Yona">Gal Yona</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Herzl 234, Rehovot, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Herzl 234, Rehovot</wicri:regionArea>
<wicri:noRegion>Rehovot</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Greenfeld, Daniel" sort="Greenfeld, Daniel" uniqKey="Greenfeld D" first="Daniel" last="Greenfeld">Daniel Greenfeld</name>
<affiliation wicri:level="1"><nlm:affiliation>Faculty of Industrial Engineering and Management, Technion University, Haifa, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Faculty of Industrial Engineering and Management, Technion University, Haifa</wicri:regionArea>
<wicri:noRegion>Haifa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sheiba, Shimon" sort="Sheiba, Shimon" uniqKey="Sheiba S" first="Shimon" last="Sheiba">Shimon Sheiba</name>
<affiliation wicri:level="1"><nlm:affiliation>Faculty of Industrial Engineering and Management, Technion University, Haifa, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Faculty of Industrial Engineering and Management, Technion University, Haifa</wicri:regionArea>
<wicri:noRegion>Haifa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Somer, Jonathan" sort="Somer, Jonathan" uniqKey="Somer J" first="Jonathan" last="Somer">Jonathan Somer</name>
<affiliation wicri:level="1"><nlm:affiliation>Faculty of Industrial Engineering and Management, Technion University, Haifa, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Faculty of Industrial Engineering and Management, Technion University, Haifa</wicri:regionArea>
<wicri:noRegion>Haifa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bachmat, Eitan" sort="Bachmat, Eitan" uniqKey="Bachmat E" first="Eitan" last="Bachmat">Eitan Bachmat</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Computer Science, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Department of Computer Science, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva</wicri:regionArea>
<wicri:noRegion>Be'er Sheva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rothblum, Guy N" sort="Rothblum, Guy N" uniqKey="Rothblum G" first="Guy N" last="Rothblum">Guy N. Rothblum</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Herzl 234, Rehovot, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Herzl 234, Rehovot</wicri:regionArea>
<wicri:noRegion>Rehovot</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shalit, Uri" sort="Shalit, Uri" uniqKey="Shalit U" first="Uri" last="Shalit">Uri Shalit</name>
<affiliation wicri:level="1"><nlm:affiliation>Faculty of Industrial Engineering and Management, Technion University, Haifa, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Faculty of Industrial Engineering and Management, Technion University, Haifa</wicri:regionArea>
<wicri:noRegion>Haifa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Netzer, Doron" sort="Netzer, Doron" uniqKey="Netzer D" first="Doron" last="Netzer">Doron Netzer</name>
<affiliation wicri:level="1"><nlm:affiliation>Community Medical Services Division, Clalit Health Services, Arlozorov 101, Tel Aviv, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Community Medical Services Division, Clalit Health Services, Arlozorov 101, Tel Aviv</wicri:regionArea>
<wicri:noRegion>Tel Aviv</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Balicer, Ran" sort="Balicer, Ran" uniqKey="Balicer R" first="Ran" last="Balicer">Ran Balicer</name>
<affiliation wicri:level="1"><nlm:affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan</wicri:regionArea>
<wicri:noRegion>Ramat-Gan</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>School of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>School of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva</wicri:regionArea>
<wicri:noRegion>Be'er Sheva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Dagan, Noa" sort="Dagan, Noa" uniqKey="Dagan N" first="Noa" last="Dagan">Noa Dagan</name>
<affiliation wicri:level="1"><nlm:affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel. noada@clalit.org.il.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan</wicri:regionArea>
<wicri:noRegion>Ramat-Gan</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>School of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva, Israel. noada@clalit.org.il.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>School of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva</wicri:regionArea>
<wicri:noRegion>Be'er Sheva</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>Department of Computer Science, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva, Israel. noada@clalit.org.il.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Department of Computer Science, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva</wicri:regionArea>
<wicri:noRegion>Be'er Sheva</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Nature communications</title>
<idno type="eISSN">2041-1723</idno>
<imprint><date when="2020" type="published">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent (MeSH)</term>
<term>Adult (MeSH)</term>
<term>Aged (MeSH)</term>
<term>Aged, 80 and over (MeSH)</term>
<term>Betacoronavirus (isolation & purification)</term>
<term>Child (MeSH)</term>
<term>Cohort Studies (MeSH)</term>
<term>Coronavirus Infections (mortality)</term>
<term>Coronavirus Infections (virology)</term>
<term>Female (MeSH)</term>
<term>Forecasting (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Israel (epidemiology)</term>
<term>Male (MeSH)</term>
<term>Middle Aged (MeSH)</term>
<term>Models, Statistical (MeSH)</term>
<term>Pandemics (MeSH)</term>
<term>Pneumonia, Viral (mortality)</term>
<term>Pneumonia, Viral (virology)</term>
<term>ROC Curve (MeSH)</term>
<term>Retrospective Studies (MeSH)</term>
<term>Risk Factors (MeSH)</term>
<term>Young Adult (MeSH)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent (MeSH)</term>
<term>Adulte (MeSH)</term>
<term>Adulte d'âge moyen (MeSH)</term>
<term>Betacoronavirus (isolement et purification)</term>
<term>Courbe ROC (MeSH)</term>
<term>Enfant (MeSH)</term>
<term>Facteurs de risque (MeSH)</term>
<term>Femelle (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Infections à coronavirus (mortalité)</term>
<term>Infections à coronavirus (virologie)</term>
<term>Israël (épidémiologie)</term>
<term>Jeune adulte (MeSH)</term>
<term>Modèles statistiques (MeSH)</term>
<term>Mâle (MeSH)</term>
<term>Pandémies (MeSH)</term>
<term>Pneumopathie virale (mortalité)</term>
<term>Pneumopathie virale (virologie)</term>
<term>Prévision (MeSH)</term>
<term>Sujet âgé (MeSH)</term>
<term>Sujet âgé de 80 ans ou plus (MeSH)</term>
<term>Études de cohortes (MeSH)</term>
<term>Études rétrospectives (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Israel</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Betacoronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Betacoronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Infections à coronavirus</term>
<term>Pneumopathie virale</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections à coronavirus</term>
<term>Pneumopathie virale</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Israël</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Child</term>
<term>Cohort Studies</term>
<term>Female</term>
<term>Forecasting</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Models, Statistical</term>
<term>Pandemics</term>
<term>ROC Curve</term>
<term>Retrospective Studies</term>
<term>Risk Factors</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Courbe ROC</term>
<term>Enfant</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Humains</term>
<term>Jeune adulte</term>
<term>Modèles statistiques</term>
<term>Mâle</term>
<term>Pandémies</term>
<term>Prévision</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Études de cohortes</term>
<term>Études rétrospectives</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Israël</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">At the COVID-19 pandemic onset, when individual-level data of COVID-19 patients were not yet available, there was already a need for risk predictors to support prevention and treatment decisions. Here, we report a hybrid strategy to create such a predictor, combining the development of a baseline severe respiratory infection risk predictor and a post-processing method to calibrate the predictions to reported COVID-19 case-fatality rates. With the accumulation of a COVID-19 patient cohort, this predictor is validated to have good discrimination (area under the receiver-operating characteristics curve of 0.943) and calibration (markedly improved compared to that of the baseline predictor). At a 5% risk threshold, 15% of patients are marked as high-risk, achieving a sensitivity of 88%. We thus demonstrate that even at the onset of a pandemic, shrouded in epidemiologic fog of war, it is possible to provide a useful risk predictor, now widely used in a large healthcare organization.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32895375</PMID>
<DateCompleted><Year>2020</Year>
<Month>09</Month>
<Day>23</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>10</Month>
<Day>01</Day>
</DateRevised>
<Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">2041-1723</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>11</Volume>
<Issue>1</Issue>
<PubDate><Year>2020</Year>
<Month>09</Month>
<Day>07</Day>
</PubDate>
</JournalIssue>
<Title>Nature communications</Title>
<ISOAbbreviation>Nat Commun</ISOAbbreviation>
</Journal>
<ArticleTitle>Developing a COVID-19 mortality risk prediction model when individual-level data are not available.</ArticleTitle>
<Pagination><MedlinePgn>4439</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1038/s41467-020-18297-9</ELocationID>
<Abstract><AbstractText>At the COVID-19 pandemic onset, when individual-level data of COVID-19 patients were not yet available, there was already a need for risk predictors to support prevention and treatment decisions. Here, we report a hybrid strategy to create such a predictor, combining the development of a baseline severe respiratory infection risk predictor and a post-processing method to calibrate the predictions to reported COVID-19 case-fatality rates. With the accumulation of a COVID-19 patient cohort, this predictor is validated to have good discrimination (area under the receiver-operating characteristics curve of 0.943) and calibration (markedly improved compared to that of the baseline predictor). At a 5% risk threshold, 15% of patients are marked as high-risk, achieving a sensitivity of 88%. We thus demonstrate that even at the onset of a pandemic, shrouded in epidemiologic fog of war, it is possible to provide a useful risk predictor, now widely used in a large healthcare organization.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Barda</LastName>
<ForeName>Noam</ForeName>
<Initials>N</Initials>
<Identifier Source="ORCID">0000-0002-3400-235X</Identifier>
<AffiliationInfo><Affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>School of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva, Israel.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Computer Science, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva, Israel.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Riesel</LastName>
<ForeName>Dan</ForeName>
<Initials>D</Initials>
<Identifier Source="ORCID">0000-0001-9716-122X</Identifier>
<AffiliationInfo><Affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Akriv</LastName>
<ForeName>Amichay</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Levy</LastName>
<ForeName>Joseph</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Finkel</LastName>
<ForeName>Uriah</ForeName>
<Initials>U</Initials>
<AffiliationInfo><Affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Yona</LastName>
<ForeName>Gal</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Herzl 234, Rehovot, Israel.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Greenfeld</LastName>
<ForeName>Daniel</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Faculty of Industrial Engineering and Management, Technion University, Haifa, Israel.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sheiba</LastName>
<ForeName>Shimon</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Faculty of Industrial Engineering and Management, Technion University, Haifa, Israel.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Somer</LastName>
<ForeName>Jonathan</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Faculty of Industrial Engineering and Management, Technion University, Haifa, Israel.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bachmat</LastName>
<ForeName>Eitan</ForeName>
<Initials>E</Initials>
<Identifier Source="ORCID">0000-0001-7153-100X</Identifier>
<AffiliationInfo><Affiliation>Department of Computer Science, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva, Israel.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Rothblum</LastName>
<ForeName>Guy N</ForeName>
<Initials>GN</Initials>
<AffiliationInfo><Affiliation>Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Herzl 234, Rehovot, Israel.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Shalit</LastName>
<ForeName>Uri</ForeName>
<Initials>U</Initials>
<AffiliationInfo><Affiliation>Faculty of Industrial Engineering and Management, Technion University, Haifa, Israel.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Netzer</LastName>
<ForeName>Doron</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Community Medical Services Division, Clalit Health Services, Arlozorov 101, Tel Aviv, Israel.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Balicer</LastName>
<ForeName>Ran</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>School of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva, Israel.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Dagan</LastName>
<ForeName>Noa</ForeName>
<Initials>N</Initials>
<Identifier Source="ORCID">0000-0001-8811-7825</Identifier>
<AffiliationInfo><Affiliation>Clalit Research Institute, Innovation Division, Clalit Health Services, Toval 40, Ramat-Gan, Israel. noada@clalit.org.il.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>School of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva, Israel. noada@clalit.org.il.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Computer Science, Ben Gurion University of the Negev, Ben-Gurion blvd. 1, Be'er Sheva, Israel. noada@clalit.org.il.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2020</Year>
<Month>09</Month>
<Day>07</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>Nat Commun</MedlineTA>
<NlmUniqueID>101528555</NlmUniqueID>
<ISSNLinking>2041-1723</ISSNLinking>
</MedlineJournalInfo>
<SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName>
<SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName>
</SupplMeshList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="N">Betacoronavirus</DescriptorName>
<QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015331" MajorTopicYN="N">Cohort Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName>
<QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005544" MajorTopicYN="N">Forecasting</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007557" MajorTopicYN="N" Type="Geographic">Israel</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015233" MajorTopicYN="Y">Models, Statistical</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName>
<QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012372" MajorTopicYN="N">ROC Curve</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012307" MajorTopicYN="N">Risk Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year>
<Month>05</Month>
<Day>31</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2020</Year>
<Month>08</Month>
<Day>13</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2020</Year>
<Month>9</Month>
<Day>8</Day>
<Hour>5</Hour>
<Minute>19</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2020</Year>
<Month>9</Month>
<Day>9</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2020</Year>
<Month>9</Month>
<Day>24</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>epublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">32895375</ArticleId>
<ArticleId IdType="doi">10.1038/s41467-020-18297-9</ArticleId>
<ArticleId IdType="pii">10.1038/s41467-020-18297-9</ArticleId>
<ArticleId IdType="pmc">PMC7477233</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>Br J Surg. 2015 Feb;102(3):148-58</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25627261</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>BMJ. 2007 Jul 21;335(7611):136</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17615182</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2020 Apr 30;382(18):e41</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32212516</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2020 Jul 28;71(15):833-840</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32296824</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>BMJ. 2020 Feb 18;368:m641</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32071063</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Signal Transduct Target Ther. 2020 Mar 27;5(1):33</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32296069</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2017 Jun 29;376(26):2507-2509</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28657867</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Epidemiology. 2010 Jan;21(1):128-38</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20010215</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Circulation. 1998 May 12;97(18):1837-47</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9603539</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2018 Nov 10;392(10159):1736-1788</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30496103</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>BMJ. 2020 Apr 7;369:m1328</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32265220</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>BMJ. 2009 Nov 19;339:b4229</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19926696</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Osteoporos Int. 2008 Apr;19(4):385-97</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18292978</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>BMJ. 2016 Jan 25;352:i6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26810254</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Med. 2020 Apr;26(4):506-510</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32284616</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Israël</li>
</country>
</list>
<tree><country name="Israël"><noRegion><name sortKey="Barda, Noam" sort="Barda, Noam" uniqKey="Barda N" first="Noam" last="Barda">Noam Barda</name>
</noRegion>
<name sortKey="Akriv, Amichay" sort="Akriv, Amichay" uniqKey="Akriv A" first="Amichay" last="Akriv">Amichay Akriv</name>
<name sortKey="Bachmat, Eitan" sort="Bachmat, Eitan" uniqKey="Bachmat E" first="Eitan" last="Bachmat">Eitan Bachmat</name>
<name sortKey="Balicer, Ran" sort="Balicer, Ran" uniqKey="Balicer R" first="Ran" last="Balicer">Ran Balicer</name>
<name sortKey="Balicer, Ran" sort="Balicer, Ran" uniqKey="Balicer R" first="Ran" last="Balicer">Ran Balicer</name>
<name sortKey="Barda, Noam" sort="Barda, Noam" uniqKey="Barda N" first="Noam" last="Barda">Noam Barda</name>
<name sortKey="Barda, Noam" sort="Barda, Noam" uniqKey="Barda N" first="Noam" last="Barda">Noam Barda</name>
<name sortKey="Dagan, Noa" sort="Dagan, Noa" uniqKey="Dagan N" first="Noa" last="Dagan">Noa Dagan</name>
<name sortKey="Dagan, Noa" sort="Dagan, Noa" uniqKey="Dagan N" first="Noa" last="Dagan">Noa Dagan</name>
<name sortKey="Dagan, Noa" sort="Dagan, Noa" uniqKey="Dagan N" first="Noa" last="Dagan">Noa Dagan</name>
<name sortKey="Finkel, Uriah" sort="Finkel, Uriah" uniqKey="Finkel U" first="Uriah" last="Finkel">Uriah Finkel</name>
<name sortKey="Greenfeld, Daniel" sort="Greenfeld, Daniel" uniqKey="Greenfeld D" first="Daniel" last="Greenfeld">Daniel Greenfeld</name>
<name sortKey="Levy, Joseph" sort="Levy, Joseph" uniqKey="Levy J" first="Joseph" last="Levy">Joseph Levy</name>
<name sortKey="Netzer, Doron" sort="Netzer, Doron" uniqKey="Netzer D" first="Doron" last="Netzer">Doron Netzer</name>
<name sortKey="Riesel, Dan" sort="Riesel, Dan" uniqKey="Riesel D" first="Dan" last="Riesel">Dan Riesel</name>
<name sortKey="Rothblum, Guy N" sort="Rothblum, Guy N" uniqKey="Rothblum G" first="Guy N" last="Rothblum">Guy N. Rothblum</name>
<name sortKey="Shalit, Uri" sort="Shalit, Uri" uniqKey="Shalit U" first="Uri" last="Shalit">Uri Shalit</name>
<name sortKey="Sheiba, Shimon" sort="Sheiba, Shimon" uniqKey="Sheiba S" first="Shimon" last="Sheiba">Shimon Sheiba</name>
<name sortKey="Somer, Jonathan" sort="Somer, Jonathan" uniqKey="Somer J" first="Jonathan" last="Somer">Jonathan Somer</name>
<name sortKey="Yona, Gal" sort="Yona, Gal" uniqKey="Yona G" first="Gal" last="Yona">Gal Yona</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/CovidSeniorV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000669 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000669 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    CovidSeniorV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:32895375
   |texte=   Developing a COVID-19 mortality risk prediction model when individual-level data are not available.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:32895375" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a CovidSeniorV1

This area was generated with Dilib version V0.6.37.
Data generation: Thu Oct 15 09:49:45 2020. Site generation: Wed Jan 27 17:10:23 2021

	Serveur d'exploration sur la COVID chez les séniors
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur la COVID chez les séniors

Developing a COVID-19 mortality risk prediction model when individual-level data are not available.

Developing a COVID-19 mortality risk prediction model when individual-level data are not available.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki