Epistaxis as a marker for severe acute respiratory syndrome coronavirus-2 status - a prospective study.
Identifieur interne : 000504 ( Main/Corpus ); précédent : 000503; suivant : 000505Epistaxis as a marker for severe acute respiratory syndrome coronavirus-2 status - a prospective study.
Auteurs : M H Hussain ; M. Mair ; P. ReaSource :
- The Journal of laryngology and otology [ 1748-5460 ] ; 2020.
English descriptors
- KwdEn :
- Adult (MeSH), Aged (MeSH), Aged, 80 and over (MeSH), Betacoronavirus (genetics), Betacoronavirus (isolation & purification), Case-Control Studies (MeSH), Coronavirus Infections (complications), Coronavirus Infections (drug therapy), Coronavirus Infections (epidemiology), Coronavirus Infections (virology), Cough (diagnosis), Cough (virology), Epistaxis (diagnosis), Epistaxis (epidemiology), Epistaxis (virology), Female (MeSH), Fever (diagnosis), Fever (virology), Humans (MeSH), Male (MeSH), Middle Aged (MeSH), Olfaction Disorders (diagnosis), Olfaction Disorders (virology), Otolaryngology (standards), Pandemics (MeSH), Pneumonia, Viral (complications), Pneumonia, Viral (drug therapy), Pneumonia, Viral (epidemiology), Pneumonia, Viral (virology), Prevalence (MeSH), Prospective Studies (MeSH), Real-Time Polymerase Chain Reaction (MeSH), Tertiary Care Centers (standards), United Kingdom (epidemiology).
- MESH :
- geographic , epidemiology : United Kingdom.
- complications : Coronavirus Infections, Pneumonia, Viral.
- diagnosis : Cough, Epistaxis, Fever, Olfaction Disorders.
- drug therapy : Coronavirus Infections, Pneumonia, Viral.
- epidemiology : Coronavirus Infections, Epistaxis, Pneumonia, Viral.
- genetics : Betacoronavirus.
- isolation & purification : Betacoronavirus.
- standards : Otolaryngology, Tertiary Care Centers.
- virology : Coronavirus Infections, Cough, Epistaxis, Fever, Olfaction Disorders, Pneumonia, Viral.
- Adult, Aged, Aged, 80 and over, Case-Control Studies, Female, Humans, Male, Middle Aged, Pandemics, Prevalence, Prospective Studies, Real-Time Polymerase Chain Reaction.
Abstract
OBJECTIVE
To evaluate the prevalence of severe acute respiratory syndrome coronavirus-2 infection in patients presenting with epistaxis to a tertiary otolaryngology unit.
METHODS
A prospective study was conducted of 40 consecutive patients presenting with epistaxis referred to our tertiary otolaryngology unit. A group of 40 age-matched controls were also included. All patients underwent real-time reverse transcriptase polymerase chain reaction testing for severe acute respiratory syndrome coronavirus-2. Symptoms of fever, cough and anosmia were noted in the study group.
RESULTS
The mean age was 66.5 ± 22.4 years in the study group. There were 22 males (55 per cent) and 18 females (45 per cent). The mean age in the control group was 66.3 ± 22.4 years (p = 0.935). There were six positive cases for severe acute respiratory syndrome coronavirus-2 (15 per cent) in the epistaxis group and one case (2.5 per cent) in the control group. The difference was statistically significant (p = 0.05).
CONCLUSION
Epistaxis may represent a presenting symptom of severe acute respiratory syndrome coronavirus-2 infection. This may serve as a useful additional criterion for screening patients.
DOI: 10.1017/S0022215120001863
PubMed: 32838816
PubMed Central: PMC7468789
Links to Exploration step
pubmed:32838816Le document en format XML
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Rea</name><affiliation><nlm:affiliation>Department of Otolaryngology, University Hospitals of Leicester NHS Trust, UK.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32838816</idno><idno type="pmid">32838816</idno><idno type="doi">10.1017/S0022215120001863</idno><idno type="pmc">PMC7468789</idno><idno type="wicri:Area/Main/Corpus">000504</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000504</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Epistaxis as a marker for severe acute respiratory syndrome coronavirus-2 status - a prospective study.</title><author><name sortKey="Hussain, M H" sort="Hussain, M H" uniqKey="Hussain M" first="M H" last="Hussain">M H Hussain</name><affiliation><nlm:affiliation>Department of Otolaryngology, University Hospitals of Leicester NHS Trust, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Mair, M" sort="Mair, M" uniqKey="Mair M" first="M" last="Mair">M. Mair</name><affiliation><nlm:affiliation>Department of Otolaryngology, University Hospitals of Leicester NHS Trust, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Rea, P" sort="Rea, P" uniqKey="Rea P" first="P" last="Rea">P. Rea</name><affiliation><nlm:affiliation>Department of Otolaryngology, University Hospitals of Leicester NHS Trust, UK.</nlm:affiliation></affiliation></author></analytic><series><title level="j">The Journal of laryngology and otology</title><idno type="eISSN">1748-5460</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term><term>Aged (MeSH)</term><term>Aged, 80 and over (MeSH)</term><term>Betacoronavirus (genetics)</term><term>Betacoronavirus (isolation & purification)</term><term>Case-Control Studies (MeSH)</term><term>Coronavirus Infections (complications)</term><term>Coronavirus Infections (drug therapy)</term><term>Coronavirus Infections (epidemiology)</term><term>Coronavirus Infections (virology)</term><term>Cough (diagnosis)</term><term>Cough (virology)</term><term>Epistaxis (diagnosis)</term><term>Epistaxis (epidemiology)</term><term>Epistaxis (virology)</term><term>Female (MeSH)</term><term>Fever (diagnosis)</term><term>Fever (virology)</term><term>Humans (MeSH)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Olfaction Disorders (diagnosis)</term><term>Olfaction Disorders (virology)</term><term>Otolaryngology (standards)</term><term>Pandemics (MeSH)</term><term>Pneumonia, Viral (complications)</term><term>Pneumonia, Viral (drug therapy)</term><term>Pneumonia, Viral (epidemiology)</term><term>Pneumonia, Viral (virology)</term><term>Prevalence (MeSH)</term><term>Prospective Studies (MeSH)</term><term>Real-Time Polymerase Chain Reaction (MeSH)</term><term>Tertiary Care Centers (standards)</term><term>United Kingdom (epidemiology)</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>United Kingdom</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Cough</term><term>Epistaxis</term><term>Fever</term><term>Olfaction Disorders</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Epistaxis</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Betacoronavirus</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Betacoronavirus</term></keywords><keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Otolaryngology</term><term>Tertiary Care Centers</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term><term>Cough</term><term>Epistaxis</term><term>Fever</term><term>Olfaction Disorders</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Case-Control Studies</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Pandemics</term><term>Prevalence</term><term>Prospective Studies</term><term>Real-Time Polymerase Chain Reaction</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>OBJECTIVE</b></p><p>To evaluate the prevalence of severe acute respiratory syndrome coronavirus-2 infection in patients presenting with epistaxis to a tertiary otolaryngology unit.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>A prospective study was conducted of 40 consecutive patients presenting with epistaxis referred to our tertiary otolaryngology unit. A group of 40 age-matched controls were also included. All patients underwent real-time reverse transcriptase polymerase chain reaction testing for severe acute respiratory syndrome coronavirus-2. Symptoms of fever, cough and anosmia were noted in the study group.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>The mean age was 66.5 ± 22.4 years in the study group. There were 22 males (55 per cent) and 18 females (45 per cent). The mean age in the control group was 66.3 ± 22.4 years (p = 0.935). There were six positive cases for severe acute respiratory syndrome coronavirus-2 (15 per cent) in the epistaxis group and one case (2.5 per cent) in the control group. The difference was statistically significant (p = 0.05).</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>Epistaxis may represent a presenting symptom of severe acute respiratory syndrome coronavirus-2 infection. This may serve as a useful additional criterion for screening patients.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32838816</PMID><DateCompleted><Year>2020</Year><Month>10</Month><Day>01</Day></DateCompleted><DateRevised><Year>2020</Year><Month>10</Month><Day>01</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1748-5460</ISSN><JournalIssue CitedMedium="Internet"><Volume>134</Volume><Issue>8</Issue><PubDate><Year>2020</Year><Month>Aug</Month></PubDate></JournalIssue><Title>The Journal of laryngology and otology</Title><ISOAbbreviation>J Laryngol Otol</ISOAbbreviation></Journal><ArticleTitle>Epistaxis as a marker for severe acute respiratory syndrome coronavirus-2 status - a prospective study.</ArticleTitle><Pagination><MedlinePgn>717-720</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1017/S0022215120001863</ELocationID><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To evaluate the prevalence of severe acute respiratory syndrome coronavirus-2 infection in patients presenting with epistaxis to a tertiary otolaryngology unit.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">A prospective study was conducted of 40 consecutive patients presenting with epistaxis referred to our tertiary otolaryngology unit. A group of 40 age-matched controls were also included. All patients underwent real-time reverse transcriptase polymerase chain reaction testing for severe acute respiratory syndrome coronavirus-2. Symptoms of fever, cough and anosmia were noted in the study group.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">The mean age was 66.5 ± 22.4 years in the study group. There were 22 males (55 per cent) and 18 females (45 per cent). The mean age in the control group was 66.3 ± 22.4 years (p = 0.935). There were six positive cases for severe acute respiratory syndrome coronavirus-2 (15 per cent) in the epistaxis group and one case (2.5 per cent) in the control group. The difference was statistically significant (p = 0.05).</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Epistaxis may represent a presenting symptom of severe acute respiratory syndrome coronavirus-2 infection. 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DateType="Electronic"><Year>2020</Year><Month>08</Month><Day>25</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Laryngol Otol</MedlineTA><NlmUniqueID>8706896</NlmUniqueID><ISSNLinking>0022-2151</ISSNLinking></MedlineJournalInfo><SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName><SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName></SupplMeshList><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="N">Betacoronavirus</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016022" MajorTopicYN="N">Case-Control Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003371" MajorTopicYN="N">Cough</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004844" MajorTopicYN="N">Epistaxis</DescriptorName><QualifierName UI="Q000175" 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UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010036" MajorTopicYN="N">Otolaryngology</DescriptorName><QualifierName UI="Q000592" MajorTopicYN="N">standards</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015995" MajorTopicYN="N">Prevalence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D060888" 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