Pediatric liver transplantation and COVID-19: a case report.
Identifieur interne : 000A89 ( Main/Corpus ); précédent : 000A88; suivant : 000A90Pediatric liver transplantation and COVID-19: a case report.
Auteurs : Hamed Nikoupour ; Kourosh Kazemi ; Peyman Arasteh ; Saba Ghazimoghadam ; Hesameddin Eghlimi ; Naghi Dara ; Siavash Gholami ; Saman NikeghbalianSource :
- BMC surgery [ 1471-2482 ] ; 2020.
English descriptors
- KwdEn :
- MESH :
- complications : Coronavirus Infections, Pneumonia, Viral.
- etiology : Multiple Organ Failure.
- COVID-19, Child, Preschool, Humans, Intensive Care Units, Liver Transplantation, Male, Pandemics.
Abstract
BACKGROUND
Immunosuppressed patients, including individuals with organ transplantation, have been among susceptible groups with regard to COVID-19, on the other hand pediatric patients more commonly undergo a mild clinical course after acquiring COVID-19. To the best of the authors knowledge, to this date very little data exists on COVID-19 in a pediatric patient with liver transplantation.
CASE PRESENTATION
We report a three year-old boy who had liver transplantation at 18 months old. He was admitted due to dyspnea with impression of acute respiratory distress syndrome and was then transferred to the intensive care unit. Chest X-ray at admission showed bilateral infiltration. Vancomycin, meropenem, azithromycin, voriconazole and co-trimoxazole were started from the first day of admission. On day 4 of admission, with suspicion of COVID-19, hydroxychloroquine, lopinavir/ritonavir and oseltamivir were added to the antibiotic regimen. PCR was positive for COVID-19. The patient developed multi-organ failure and died on day 6 of admission.
CONCLUSIONS
For pediatric patients with organ transplantations, extreme caution should be taken, to limit and prevent their contact with COVID-19 during the outbreak, as these patients are highly susceptible to severe forms of the disease.
DOI: 10.1186/s12893-020-00878-6
PubMed: 33023552
PubMed Central: PMC7538038
Links to Exploration step
pubmed:33023552Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Pediatric liver transplantation and COVID-19: a case report.</title><author><name sortKey="Nikoupour, Hamed" sort="Nikoupour, Hamed" uniqKey="Nikoupour H" first="Hamed" last="Nikoupour">Hamed Nikoupour</name><affiliation><nlm:affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Kazemi, Kourosh" sort="Kazemi, Kourosh" uniqKey="Kazemi K" first="Kourosh" last="Kazemi">Kourosh Kazemi</name><affiliation><nlm:affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Arasteh, Peyman" sort="Arasteh, Peyman" uniqKey="Arasteh P" first="Peyman" last="Arasteh">Peyman Arasteh</name><affiliation><nlm:affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Ghazimoghadam, Saba" sort="Ghazimoghadam, Saba" uniqKey="Ghazimoghadam S" first="Saba" last="Ghazimoghadam">Saba Ghazimoghadam</name><affiliation><nlm:affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran. saba_gh_m@ymail.com.</nlm:affiliation></affiliation></author><author><name sortKey="Eghlimi, Hesameddin" sort="Eghlimi, Hesameddin" uniqKey="Eghlimi H" first="Hesameddin" last="Eghlimi">Hesameddin Eghlimi</name><affiliation><nlm:affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Dara, Naghi" sort="Dara, Naghi" uniqKey="Dara N" first="Naghi" last="Dara">Naghi Dara</name><affiliation><nlm:affiliation>Hepatology and Nutrition Research Center, Research Institute for Children's Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Gholami, Siavash" sort="Gholami, Siavash" uniqKey="Gholami S" first="Siavash" last="Gholami">Siavash Gholami</name><affiliation><nlm:affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Nikeghbalian, Saman" sort="Nikeghbalian, Saman" uniqKey="Nikeghbalian S" first="Saman" last="Nikeghbalian">Saman Nikeghbalian</name><affiliation><nlm:affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:33023552</idno><idno type="pmid">33023552</idno><idno type="doi">10.1186/s12893-020-00878-6</idno><idno type="pmc">PMC7538038</idno><idno type="wicri:Area/Main/Corpus">000A89</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000A89</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Pediatric liver transplantation and COVID-19: a case report.</title><author><name sortKey="Nikoupour, Hamed" sort="Nikoupour, Hamed" uniqKey="Nikoupour H" first="Hamed" last="Nikoupour">Hamed Nikoupour</name><affiliation><nlm:affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Kazemi, Kourosh" sort="Kazemi, Kourosh" uniqKey="Kazemi K" first="Kourosh" last="Kazemi">Kourosh Kazemi</name><affiliation><nlm:affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Arasteh, Peyman" sort="Arasteh, Peyman" uniqKey="Arasteh P" first="Peyman" last="Arasteh">Peyman Arasteh</name><affiliation><nlm:affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Ghazimoghadam, Saba" sort="Ghazimoghadam, Saba" uniqKey="Ghazimoghadam S" first="Saba" last="Ghazimoghadam">Saba Ghazimoghadam</name><affiliation><nlm:affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran. saba_gh_m@ymail.com.</nlm:affiliation></affiliation></author><author><name sortKey="Eghlimi, Hesameddin" sort="Eghlimi, Hesameddin" uniqKey="Eghlimi H" first="Hesameddin" last="Eghlimi">Hesameddin Eghlimi</name><affiliation><nlm:affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Dara, Naghi" sort="Dara, Naghi" uniqKey="Dara N" first="Naghi" last="Dara">Naghi Dara</name><affiliation><nlm:affiliation>Hepatology and Nutrition Research Center, Research Institute for Children's Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Gholami, Siavash" sort="Gholami, Siavash" uniqKey="Gholami S" first="Siavash" last="Gholami">Siavash Gholami</name><affiliation><nlm:affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Nikeghbalian, Saman" sort="Nikeghbalian, Saman" uniqKey="Nikeghbalian S" first="Saman" last="Nikeghbalian">Saman Nikeghbalian</name><affiliation><nlm:affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.</nlm:affiliation></affiliation></author></analytic><series><title level="j">BMC surgery</title><idno type="eISSN">1471-2482</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>COVID-19 (MeSH)</term><term>Child, Preschool (MeSH)</term><term>Coronavirus Infections (complications)</term><term>Humans (MeSH)</term><term>Intensive Care Units (MeSH)</term><term>Liver Transplantation (MeSH)</term><term>Male (MeSH)</term><term>Multiple Organ Failure (etiology)</term><term>Pandemics (MeSH)</term><term>Pneumonia, Viral (complications)</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Multiple Organ Failure</term></keywords><keywords scheme="MESH" xml:lang="en"><term>COVID-19</term><term>Child, Preschool</term><term>Humans</term><term>Intensive Care Units</term><term>Liver Transplantation</term><term>Male</term><term>Pandemics</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>Immunosuppressed patients, including individuals with organ transplantation, have been among susceptible groups with regard to COVID-19, on the other hand pediatric patients more commonly undergo a mild clinical course after acquiring COVID-19. To the best of the authors knowledge, to this date very little data exists on COVID-19 in a pediatric patient with liver transplantation.</p></div><div type="abstract" xml:lang="en"><p><b>CASE PRESENTATION</b></p><p>We report a three year-old boy who had liver transplantation at 18 months old. He was admitted due to dyspnea with impression of acute respiratory distress syndrome and was then transferred to the intensive care unit. Chest X-ray at admission showed bilateral infiltration. Vancomycin, meropenem, azithromycin, voriconazole and co-trimoxazole were started from the first day of admission. On day 4 of admission, with suspicion of COVID-19, hydroxychloroquine, lopinavir/ritonavir and oseltamivir were added to the antibiotic regimen. PCR was positive for COVID-19. The patient developed multi-organ failure and died on day 6 of admission.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>For pediatric patients with organ transplantations, extreme caution should be taken, to limit and prevent their contact with COVID-19 during the outbreak, as these patients are highly susceptible to severe forms of the disease.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Curated" Owner="NLM"><PMID Version="1">33023552</PMID><DateCompleted><Year>2020</Year><Month>10</Month><Day>13</Day></DateCompleted><DateRevised><Year>2020</Year><Month>12</Month><Day>18</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1471-2482</ISSN><JournalIssue CitedMedium="Internet"><Volume>20</Volume><Issue>1</Issue><PubDate><Year>2020</Year><Month>Oct</Month><Day>06</Day></PubDate></JournalIssue><Title>BMC surgery</Title><ISOAbbreviation>BMC Surg</ISOAbbreviation></Journal><ArticleTitle>Pediatric liver transplantation and COVID-19: a case report.</ArticleTitle><Pagination><MedlinePgn>224</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1186/s12893-020-00878-6</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Immunosuppressed patients, including individuals with organ transplantation, have been among susceptible groups with regard to COVID-19, on the other hand pediatric patients more commonly undergo a mild clinical course after acquiring COVID-19. To the best of the authors knowledge, to this date very little data exists on COVID-19 in a pediatric patient with liver transplantation.</AbstractText><AbstractText Label="CASE PRESENTATION" NlmCategory="METHODS">We report a three year-old boy who had liver transplantation at 18 months old. He was admitted due to dyspnea with impression of acute respiratory distress syndrome and was then transferred to the intensive care unit. Chest X-ray at admission showed bilateral infiltration. Vancomycin, meropenem, azithromycin, voriconazole and co-trimoxazole were started from the first day of admission. On day 4 of admission, with suspicion of COVID-19, hydroxychloroquine, lopinavir/ritonavir and oseltamivir were added to the antibiotic regimen. PCR was positive for COVID-19. The patient developed multi-organ failure and died on day 6 of admission.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">For pediatric patients with organ transplantations, extreme caution should be taken, to limit and prevent their contact with COVID-19 during the outbreak, as these patients are highly susceptible to severe forms of the disease.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Nikoupour</LastName><ForeName>Hamed</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kazemi</LastName><ForeName>Kourosh</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Arasteh</LastName><ForeName>Peyman</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ghazimoghadam</LastName><ForeName>Saba</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran. saba_gh_m@ymail.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eghlimi</LastName><ForeName>Hesameddin</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dara</LastName><ForeName>Naghi</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Hepatology and Nutrition Research Center, Research Institute for Children's Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gholami</LastName><ForeName>Siavash</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nikeghbalian</LastName><ForeName>Saman</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>10</Month><Day>06</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>BMC Surg</MedlineTA><NlmUniqueID>100968567</NlmUniqueID><ISSNLinking>1471-2482</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000086382" MajorTopicYN="N">COVID-19</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002675" MajorTopicYN="N">Child, Preschool</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007362" MajorTopicYN="N">Intensive Care Units</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016031" MajorTopicYN="Y">Liver Transplantation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009102" MajorTopicYN="N">Multiple Organ Failure</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">COVID-19, liver</Keyword><Keyword MajorTopicYN="N">Pediatric</Keyword><Keyword MajorTopicYN="N">Transplantation</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>05</Month><Day>13</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>09</Month><Day>23</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>10</Month><Day>7</Day><Hour>5</Hour><Minute>32</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>10</Month><Day>8</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>10</Month><Day>21</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">33023552</ArticleId><ArticleId IdType="doi">10.1186/s12893-020-00878-6</ArticleId><ArticleId IdType="pii">10.1186/s12893-020-00878-6</ArticleId><ArticleId IdType="pmc">PMC7538038</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Ann Surg. 2020 Jun 11;:</Citation><ArticleIdList><ArticleId IdType="pubmed">32541224</ArticleId></ArticleIdList></Reference><Reference><Citation>Arch Pediatr. 2020 Jul;27(5):275-276</Citation><ArticleIdList><ArticleId IdType="pubmed">32402433</ArticleId></ArticleIdList></Reference><Reference><Citation>J Korean Med Sci. 2010 Apr;25(4):527-31</Citation><ArticleIdList><ArticleId IdType="pubmed">20357992</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Microbiol Infect. 2014 Sep;20 Suppl 7:102-8</Citation><ArticleIdList><ArticleId IdType="pubmed">26451405</ArticleId></ArticleIdList></Reference><Reference><Citation>J Pediatric Infect Dis Soc. 2012 Jun;1(2):144-51</Citation><ArticleIdList><ArticleId IdType="pubmed">26619167</ArticleId></ArticleIdList></Reference><Reference><Citation>JAMA. 2020 Mar 17;323(11):1061-1069</Citation><ArticleIdList><ArticleId IdType="pubmed">32031570</ArticleId></ArticleIdList></Reference><Reference><Citation>Infect Dis Clin North Am. 2010 Jun;24(2):307-18</Citation><ArticleIdList><ArticleId IdType="pubmed">20466272</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/CovidChloroV1/Data/Main/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000A89 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Corpus/biblio.hfd -nk 000A89 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= CovidChloroV1
|flux= Main
|étape= Corpus
|type= RBID
|clé= pubmed:33023552
|texte= Pediatric liver transplantation and COVID-19: a case report.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Corpus/RBID.i -Sk "pubmed:33023552" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a CovidChloroV1
| This area was generated with Dilib version V0.6.38. |  |