Pharmacological modulation of autophagy enhances Newcastle disease virus-mediated oncolysis in drug-resistant lung cancer cells.
Identifieur interne : 000257 ( Ncbi/Merge ); précédent : 000256; suivant : 000258Pharmacological modulation of autophagy enhances Newcastle disease virus-mediated oncolysis in drug-resistant lung cancer cells.
Auteurs : Ke Jiang ; Yingchun Li ; Qiumin Zhu ; Jiansheng Xu ; Yupeng Wang ; Wuguo Deng ; Quentin Liu ; Guirong Zhang [République populaire de Chine] ; Songshu MengSource :
- BMC cancer [ 1471-2407 ] ; 2014.
Descripteurs français
- KwdFr :
- Animaux, Autophagie (), Chloroquine (pharmacologie), Embryon de poulet, Humains, Lignée cellulaire tumorale, Protéines associées aux microtubules (génétique), Résistance aux médicaments antinéoplasiques (), Sirolimus (pharmacologie), Souris, Souris nude, Techniques de knock-down de gènes, Tests d'activité antitumorale sur modèle de xénogreffe, Thérapie virale de cancers (), Transplantation tumorale, Tumeurs du poumon (), Tumeurs du poumon (anatomopathologie), Tumeurs du poumon (génétique), Virus de la maladie de Newcastle (), Virus oncolytiques ().
- MESH :
- anatomopathologie : Tumeurs du poumon.
- génétique : Protéines associées aux microtubules, Tumeurs du poumon.
- pharmacologie : Chloroquine, Sirolimus.
- Animaux, Autophagie, Embryon de poulet, Humains, Lignée cellulaire tumorale, Résistance aux médicaments antinéoplasiques, Souris, Souris nude, Techniques de knock-down de gènes, Tests d'activité antitumorale sur modèle de xénogreffe, Thérapie virale de cancers, Transplantation tumorale, Tumeurs du poumon, Virus de la maladie de Newcastle, Virus oncolytiques.
English descriptors
- KwdEn :
- Animals, Autophagy (drug effects), Cell Line, Tumor, Chick Embryo, Chloroquine (pharmacology), Drug Resistance, Neoplasm (drug effects), Gene Knockdown Techniques, Humans, Lung Neoplasms (genetics), Lung Neoplasms (pathology), Lung Neoplasms (therapy), Mice, Mice, Nude, Microtubule-Associated Proteins (genetics), Neoplasm Transplantation, Newcastle disease virus (drug effects), Oncolytic Virotherapy (methods), Oncolytic Viruses (drug effects), Sirolimus (pharmacology), Xenograft Model Antitumor Assays.
- MESH :
- chemical , genetics : Microtubule-Associated Proteins.
- chemical , pharmacology : Chloroquine, Sirolimus.
- drug effects : Autophagy, Drug Resistance, Neoplasm, Newcastle disease virus, Oncolytic Viruses.
- genetics : Lung Neoplasms.
- methods : Oncolytic Virotherapy.
- pathology : Lung Neoplasms.
- therapy : Lung Neoplasms.
- Animals, Cell Line, Tumor, Chick Embryo, Gene Knockdown Techniques, Humans, Mice, Mice, Nude, Neoplasm Transplantation, Xenograft Model Antitumor Assays.
Abstract
Oncolytic viruses represent a promising therapy against cancers with acquired drug resistance. However, low efficacy limits its clinical application. The objective of this study is to investigate whether pharmacologically modulating autophagy could enhance oncolytic Newcastle disease virus (NDV) strain NDV/FMW virotherapy of drug-resistant lung cancer cells.
DOI: 10.1186/1471-2407-14-551
PubMed: 25078870
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000286
- to stream PubMed, to step Curation: 000286
- to stream PubMed, to step Checkpoint: 000278
Links to Exploration step
pubmed:25078870Le document en format XML
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Chine</country><wicri:regionArea>Institute of Cancer Stem Cell, Dalian Medical University Cancer Center, 9 Lvshun Road South, Dalian 116044</wicri:regionArea><wicri:noRegion>Dalian 116044</wicri:noRegion></affiliation></author><author><name sortKey="Meng, Songshu" sort="Meng, Songshu" uniqKey="Meng S" first="Songshu" last="Meng">Songshu Meng</name></author></analytic><series><title level="j">BMC cancer</title><idno type="eISSN">1471-2407</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Autophagy (drug effects)</term><term>Cell Line, Tumor</term><term>Chick Embryo</term><term>Chloroquine (pharmacology)</term><term>Drug Resistance, Neoplasm (drug effects)</term><term>Gene Knockdown Techniques</term><term>Humans</term><term>Lung Neoplasms (genetics)</term><term>Lung Neoplasms (pathology)</term><term>Lung Neoplasms (therapy)</term><term>Mice</term><term>Mice, Nude</term><term>Microtubule-Associated Proteins (genetics)</term><term>Neoplasm Transplantation</term><term>Newcastle disease virus (drug effects)</term><term>Oncolytic Virotherapy (methods)</term><term>Oncolytic Viruses (drug effects)</term><term>Sirolimus (pharmacology)</term><term>Xenograft Model Antitumor Assays</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Autophagie ()</term><term>Chloroquine (pharmacologie)</term><term>Embryon de poulet</term><term>Humains</term><term>Lignée cellulaire tumorale</term><term>Protéines associées aux microtubules (génétique)</term><term>Résistance aux médicaments antinéoplasiques ()</term><term>Sirolimus (pharmacologie)</term><term>Souris</term><term>Souris nude</term><term>Techniques de knock-down de gènes</term><term>Tests d'activité antitumorale sur modèle de xénogreffe</term><term>Thérapie virale de cancers ()</term><term>Transplantation tumorale</term><term>Tumeurs du poumon ()</term><term>Tumeurs du poumon (anatomopathologie)</term><term>Tumeurs du poumon (génétique)</term><term>Virus de la maladie de Newcastle ()</term><term>Virus oncolytiques ()</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Microtubule-Associated Proteins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Chloroquine</term><term>Sirolimus</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Tumeurs du poumon</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Autophagy</term><term>Drug Resistance, Neoplasm</term><term>Newcastle disease virus</term><term>Oncolytic Viruses</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Lung Neoplasms</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Protéines associées aux microtubules</term><term>Tumeurs du poumon</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Oncolytic Virotherapy</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Lung Neoplasms</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Chloroquine</term><term>Sirolimus</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Lung Neoplasms</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Cell Line, Tumor</term><term>Chick Embryo</term><term>Gene Knockdown Techniques</term><term>Humans</term><term>Mice</term><term>Mice, Nude</term><term>Neoplasm Transplantation</term><term>Xenograft Model Antitumor Assays</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Autophagie</term><term>Embryon de poulet</term><term>Humains</term><term>Lignée cellulaire tumorale</term><term>Résistance aux médicaments antinéoplasiques</term><term>Souris</term><term>Souris nude</term><term>Techniques de knock-down de gènes</term><term>Tests d'activité antitumorale sur modèle de xénogreffe</term><term>Thérapie virale de cancers</term><term>Transplantation tumorale</term><term>Tumeurs du poumon</term><term>Virus de la maladie de Newcastle</term><term>Virus oncolytiques</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Oncolytic viruses represent a promising therapy against cancers with acquired drug resistance. However, low efficacy limits its clinical application. The objective of this study is to investigate whether pharmacologically modulating autophagy could enhance oncolytic Newcastle disease virus (NDV) strain NDV/FMW virotherapy of drug-resistant lung cancer cells.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">25078870</PMID><DateCompleted><Year>2015</Year><Month>04</Month><Day>20</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1471-2407</ISSN><JournalIssue CitedMedium="Internet"><Volume>14</Volume><PubDate><Year>2014</Year><Month>Jul</Month><Day>30</Day></PubDate></JournalIssue><Title>BMC cancer</Title><ISOAbbreviation>BMC Cancer</ISOAbbreviation></Journal><ArticleTitle>Pharmacological modulation of autophagy enhances Newcastle disease virus-mediated oncolysis in drug-resistant lung cancer cells.</ArticleTitle><Pagination><MedlinePgn>551</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1186/1471-2407-14-551</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Oncolytic viruses represent a promising therapy against cancers with acquired drug resistance. However, low efficacy limits its clinical application. The objective of this study is to investigate whether pharmacologically modulating autophagy could enhance oncolytic Newcastle disease virus (NDV) strain NDV/FMW virotherapy of drug-resistant lung cancer cells.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">The effect of NDV/FMW infection on autophagy machinery in A549 lung cancer cell lines resistant to cisplatin (A549/DDP) or paclitaxel (A549/PTX) was investigated by detection of GFP-microtubule-associated protein 1 light chain 3 (GFP-LC3) puncta, formation of double-membrane vesicles and conversion of the nonlipidated form of LC3 (LC3-I) to the phosphatidylethanolamine-conjugated form (LC3-II). The effects of autophagy inhibitor chloroquine (CQ) and autophagy inducer rapamycin on NDV/FMW-mediated antitumor activity were evaluated both in culture cells and in mice bearing drug-resistant lung cancer cells.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">We show that NDV/FMW triggers autophagy in A549/PTX cells via dampening the class I PI3K/Akt/mTOR/p70S6K pathway, which inhibits autophagy. On the contrary, NDV/FMW infection attenuates the autophagic process in A549/DDP cells through the activation of the negative regulatory pathway. Furthermore, combination with CQ or knockdown of ATG5 significantly enhances NDV/FMW-mediated antitumor effects on A549/DDP cells, while the oncolytic efficacy of NDV/FMW in A549/PTX cells is significantly improved by rapamycin. Interestingly, autophagy modulation does not increase virus progeny in these drug resistant cells. Importantly, CQ or rapamycin significantly potentiates NDV/FMW oncolytic activity in mice bearing A549/DDP or A549/PTX cells respectively.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">These results demonstrate that combination treatment with autophagy modulators is an effective strategy to augment the therapeutic activity of NDV/FMW against drug-resistant lung cancers.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Jiang</LastName><ForeName>Ke</ForeName><Initials>K</Initials></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Yingchun</ForeName><Initials>Y</Initials></Author><Author ValidYN="Y"><LastName>Zhu</LastName><ForeName>Qiumin</ForeName><Initials>Q</Initials></Author><Author ValidYN="Y"><LastName>Xu</LastName><ForeName>Jiansheng</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Yupeng</ForeName><Initials>Y</Initials></Author><Author ValidYN="Y"><LastName>Deng</LastName><ForeName>Wuguo</ForeName><Initials>W</Initials></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>Quentin</ForeName><Initials>Q</Initials></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Guirong</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Institute of Cancer Stem Cell, Dalian Medical University Cancer Center, 9 Lvshun Road South, Dalian 116044, China. zhang.lth@163.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Meng</LastName><ForeName>Songshu</ForeName><Initials>S</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2014</Year><Month>07</Month><Day>30</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>BMC Cancer</MedlineTA><NlmUniqueID>100967800</NlmUniqueID><ISSNLinking>1471-2407</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D008869">Microtubule-Associated Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>886U3H6UFF</RegistryNumber><NameOfSubstance UI="D002738">Chloroquine</NameOfSubstance></Chemical><Chemical><RegistryNumber>W36ZG6FT64</RegistryNumber><NameOfSubstance UI="D020123">Sirolimus</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001343" MajorTopicYN="N">Autophagy</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D045744" MajorTopicYN="N">Cell Line, Tumor</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002642" MajorTopicYN="N">Chick Embryo</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002738" MajorTopicYN="N">Chloroquine</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D019008" MajorTopicYN="N">Drug Resistance, Neoplasm</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D055785" MajorTopicYN="N">Gene Knockdown Techniques</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008175" MajorTopicYN="N">Lung Neoplasms</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D051379" MajorTopicYN="N">Mice</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008819" MajorTopicYN="N">Mice, Nude</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008869" MajorTopicYN="N">Microtubule-Associated Proteins</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009368" MajorTopicYN="N">Neoplasm Transplantation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009522" MajorTopicYN="N">Newcastle disease virus</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D050130" MajorTopicYN="Y">Oncolytic Virotherapy</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D050504" MajorTopicYN="N">Oncolytic Viruses</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020123" MajorTopicYN="N">Sirolimus</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D023041" MajorTopicYN="N">Xenograft Model Antitumor Assays</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2014</Year><Month>01</Month><Day>27</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2014</Year><Month>07</Month><Day>22</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2014</Year><Month>8</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2014</Year><Month>8</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate 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26;107(4):1576-81</Citation><ArticleIdList><ArticleId IdType="pubmed">20080710</ArticleId></ArticleIdList></Reference><Reference><Citation>Virol J. 2013;10:293</Citation><ArticleIdList><ArticleId IdType="pubmed">24059864</ArticleId></ArticleIdList></Reference><Reference><Citation>Cancer Lett. 2012 Apr 1;317(1):56-64</Citation><ArticleIdList><ArticleId IdType="pubmed">22095029</ArticleId></ArticleIdList></Reference><Reference><Citation>J Gen Virol. 2012 Aug;93(Pt 8):1664-72</Citation><ArticleIdList><ArticleId IdType="pubmed">22622327</ArticleId></ArticleIdList></Reference><Reference><Citation>J Surg Res. 1992 May;52(5):448-53</Citation><ArticleIdList><ArticleId IdType="pubmed">1619912</ArticleId></ArticleIdList></Reference><Reference><Citation>Cancer Gene Ther. 2008 Dec;15(12):795-807</Citation><ArticleIdList><ArticleId IdType="pubmed">18535620</ArticleId></ArticleIdList></Reference><Reference><Citation>Expert Opin Biol Ther. 2013 Jun;13(6):863-73</Citation><ArticleIdList><ArticleId IdType="pubmed">23488666</ArticleId></ArticleIdList></Reference><Reference><Citation>Chemotherapy. 2013;59(1):8-13</Citation><ArticleIdList><ArticleId IdType="pubmed">23635552</ArticleId></ArticleIdList></Reference><Reference><Citation>Arch Virol. 2011 Aug;156(8):1335-44</Citation><ArticleIdList><ArticleId IdType="pubmed">21625975</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Death Dis. 2012;3:e260</Citation><ArticleIdList><ArticleId IdType="pubmed">22278287</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell Biol. 2005 Feb;25(3):1025-40</Citation><ArticleIdList><ArticleId IdType="pubmed">15657430</ArticleId></ArticleIdList></Reference><Reference><Citation>Cancer Biol Ther. 2014 May;15(5):570-7</Citation><ArticleIdList><ArticleId IdType="pubmed">24556908</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2011 May;85(10):4720-9</Citation><ArticleIdList><ArticleId IdType="pubmed">21367888</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2010 Jan;84(1):639-46</Citation><ArticleIdList><ArticleId IdType="pubmed">19864394</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16281-6</Citation><ArticleIdList><ArticleId IdType="pubmed">19805294</ArticleId></ArticleIdList></Reference><Reference><Citation>Front Oncol. 2014 Apr 10;4:74</Citation><ArticleIdList><ArticleId IdType="pubmed">24782985</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2013;8(9):e73650</Citation><ArticleIdList><ArticleId IdType="pubmed">24023896</ArticleId></ArticleIdList></Reference><Reference><Citation>Cancer Immunol Immunother. 2011 Oct;60(10):1461-72</Citation><ArticleIdList><ArticleId IdType="pubmed">21656158</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2011 Jun;85(12):6015-23</Citation><ArticleIdList><ArticleId IdType="pubmed">21471241</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Cell Biol. 2007 Oct;9(10):1102-9</Citation><ArticleIdList><ArticleId IdType="pubmed">17909521</ArticleId></ArticleIdList></Reference><Reference><Citation>J Pathol. 2010 May;221(1):3-12</Citation><ArticleIdList><ArticleId IdType="pubmed">20225336</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Opin Virol. 2012 Oct;2(5):629-35</Citation><ArticleIdList><ArticleId IdType="pubmed">22910124</ArticleId></ArticleIdList></Reference><Reference><Citation>Arch Immunol Ther Exp (Warsz). 2013 Feb;61(1):43-58</Citation><ArticleIdList><ArticleId IdType="pubmed">23229678</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Opin Cell Biol. 2012 Aug;24(4):496-501</Citation><ArticleIdList><ArticleId IdType="pubmed">22664348</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Cancer Res. 2009 Apr 15;15(8):2777-88</Citation><ArticleIdList><ArticleId IdType="pubmed">19351762</ArticleId></ArticleIdList></Reference><Reference><Citation>Cancer Biother Radiopharm. 2010 Feb;25(1):75-80</Citation><ArticleIdList><ArticleId IdType="pubmed">20187799</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 2011 Jul 20;416(1-2):9-15</Citation><ArticleIdList><ArticleId IdType="pubmed">21575980</ArticleId></ArticleIdList></Reference><Reference><Citation>EMBO J. 2000 Nov 1;19(21):5720-8</Citation><ArticleIdList><ArticleId IdType="pubmed">11060023</ArticleId></ArticleIdList></Reference><Reference><Citation>Am J Ther. 2003 Jul-Aug;10(4):282-8</Citation><ArticleIdList><ArticleId IdType="pubmed">12845392</ArticleId></ArticleIdList></Reference><Reference><Citation>Food Chem Toxicol. 2012 Mar;50(3-4):1060-5</Citation><ArticleIdList><ArticleId IdType="pubmed">22120505</ArticleId></ArticleIdList></Reference><Reference><Citation>Oncogene. 2013 Feb 7;32(6):736-46</Citation><ArticleIdList><ArticleId IdType="pubmed">22430212</ArticleId></ArticleIdList></Reference><Reference><Citation>Cancer Res. 2010 Jan 15;70(2):598-608</Citation><ArticleIdList><ArticleId IdType="pubmed">20068158</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Oncol. 2000 Feb;16(2):363-73</Citation><ArticleIdList><ArticleId IdType="pubmed">10639582</ArticleId></ArticleIdList></Reference><Reference><Citation>Arch Virol. 2012 Jun;157(6):1011-8</Citation><ArticleIdList><ArticleId IdType="pubmed">22398914</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cancer Ther. 2005 Sep;4(9):1311-9</Citation><ArticleIdList><ArticleId IdType="pubmed">16170022</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2006 Aug;80(15):7522-34</Citation><ArticleIdList><ArticleId IdType="pubmed">16840332</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2007 Mar;81(6):2817-30</Citation><ArticleIdList><ArticleId IdType="pubmed">17215292</ArticleId></ArticleIdList></Reference><Reference><Citation>Intervirology. 2012;55(4):276-86</Citation><ArticleIdList><ArticleId IdType="pubmed">21865658</ArticleId></ArticleIdList></Reference><Reference><Citation>Autophagy. 2012 Dec;8(12):1798-810</Citation><ArticleIdList><ArticleId IdType="pubmed">23026799</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Ther. 2008 Mar;16(3):487-93</Citation><ArticleIdList><ArticleId IdType="pubmed">18253154</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2014 Jan;88(1):525-37</Citation><ArticleIdList><ArticleId IdType="pubmed">24173218</ArticleId></ArticleIdList></Reference><Reference><Citation>Eur J Cancer. 2011 Jul;47(10):1585-94</Citation><ArticleIdList><ArticleId IdType="pubmed">21371883</ArticleId></ArticleIdList></Reference><Reference><Citation>Hum Gene Ther. 2012 Jun;23(6):623-34</Citation><ArticleIdList><ArticleId IdType="pubmed">22475378</ArticleId></ArticleIdList></Reference><Reference><Citation>Anticancer Drugs. 2013 Jan;24(1):14-9</Citation><ArticleIdList><ArticleId IdType="pubmed">23111416</ArticleId></ArticleIdList></Reference><Reference><Citation>Cancer Lett. 2007 Jun 18;251(1):1-16</Citation><ArticleIdList><ArticleId IdType="pubmed">17125914</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell. 2010 Oct 22;40(2):280-93</Citation><ArticleIdList><ArticleId IdType="pubmed">20965422</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cancer. 2013;12(1):103</Citation><ArticleIdList><ArticleId IdType="pubmed">24020520</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):15077-82</Citation><ArticleIdList><ArticleId IdType="pubmed">14657337</ArticleId></ArticleIdList></Reference><Reference><Citation>Gene Ther. 2008 Sep;15(17):1233-9</Citation><ArticleIdList><ArticleId IdType="pubmed">18580968</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2013;8(1):e54193</Citation><ArticleIdList><ArticleId IdType="pubmed">23349823</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Invest. 2007 Feb;117(2):326-36</Citation><ArticleIdList><ArticleId IdType="pubmed">17235397</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Oncol. 2007 Oct 1;25(28):4350-7</Citation><ArticleIdList><ArticleId IdType="pubmed">17906199</ArticleId></ArticleIdList></Reference><Reference><Citation>J Cell Mol Med. 2013 Jan;17(1):12-29</Citation><ArticleIdList><ArticleId IdType="pubmed">23301705</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><noCountry><name sortKey="Deng, Wuguo" sort="Deng, Wuguo" uniqKey="Deng W" first="Wuguo" last="Deng">Wuguo Deng</name><name sortKey="Jiang, Ke" sort="Jiang, Ke" uniqKey="Jiang K" first="Ke" last="Jiang">Ke Jiang</name><name sortKey="Li, Yingchun" sort="Li, Yingchun" uniqKey="Li Y" first="Yingchun" last="Li">Yingchun Li</name><name sortKey="Liu, Quentin" sort="Liu, Quentin" uniqKey="Liu Q" first="Quentin" last="Liu">Quentin Liu</name><name sortKey="Meng, Songshu" sort="Meng, Songshu" uniqKey="Meng S" first="Songshu" last="Meng">Songshu Meng</name><name sortKey="Wang, Yupeng" sort="Wang, Yupeng" uniqKey="Wang Y" first="Yupeng" last="Wang">Yupeng Wang</name><name sortKey="Xu, Jiansheng" sort="Xu, Jiansheng" uniqKey="Xu J" first="Jiansheng" last="Xu">Jiansheng Xu</name><name sortKey="Zhu, Qiumin" sort="Zhu, Qiumin" uniqKey="Zhu Q" first="Qiumin" last="Zhu">Qiumin Zhu</name></noCountry><country name="République populaire de Chine"><noRegion><name sortKey="Zhang, Guirong" sort="Zhang, Guirong" uniqKey="Zhang G" first="Guirong" last="Zhang">Guirong Zhang</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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