Activity of Chitosan and Its Derivatives against Leishmania major and Leishmania mexicanaIn Vitro
Identifieur interne : 000D67 ( Ncbi/Curation ); précédent : 000D66; suivant : 000D68Activity of Chitosan and Its Derivatives against Leishmania major and Leishmania mexicanaIn Vitro
Auteurs : Alaa Riezk [Royaume-Uni] ; John G. Raynes [Royaume-Uni] ; Vanessa Yardley [Royaume-Uni] ; Sudaxshina Murdan [Royaume-Uni] ; Simon L. Croft [Royaume-Uni]Source :
- Antimicrobial Agents and Chemotherapy [ 0066-4804 ] ; 2020.
Abstract
There is an urgent need for safe, efficacious, affordable, and field-adapted drugs for the treatment of cutaneous leishmaniasis, which newly affects around 1.5 million people worldwide annually. Chitosan, a biodegradable cationic polysaccharide, has previously been reported to have antimicrobial, antileishmanial, and immunostimulatory activities.
Url:
DOI: 10.1128/AAC.01772-19
PubMed: 31871082
PubMed Central: 7038302
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PMC:7038302Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>There is an urgent need for safe, efficacious, affordable, and field-adapted drugs for the treatment of cutaneous leishmaniasis, which newly affects around 1.5 million people worldwide annually. Chitosan, a biodegradable cationic polysaccharide, has previously been reported to have antimicrobial, antileishmanial, and immunostimulatory activities.</p>
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