Recurrent fever of unknown fungal infection in a low-risk patient
Identifieur interne : 000923 ( Ncbi/Curation ); précédent : 000922; suivant : 000924Recurrent fever of unknown fungal infection in a low-risk patient
Auteurs : Tang-Meng Guo [République populaire de Chine] ; Yu Ye ; Li-Li Huang [République populaire de Chine] ; Bei Cheng [République populaire de Chine]Source :
- Medicine [ 0025-7974 ] ; 2019.
Abstract
Fungal infectious disease does not usually occur in low-risk patients. Clinicians tend to ignore the role of fungi in the fevers of low-risk patients. If there is not timely control of fungal infections and associated fever, the disease will continue to worsen, resulting in physical dysfunction or death.
Recurrent fever continued for 1 month in a young adult.
Non-albicans Candida (NAC) species probably was the main pathogen in this case based on the resolution of fever after capsofungin administration.
The fever and the associated indicators, including white blood cell count, C-reaction protein, erythrocyte sedimentation rate, and BDG levels, showed improvement quickly. The patient left the hospital successfully after 18 days of caspofungin treatment. There was no recurrent fever at a follow-up of 1 year.
Clinicians should be aware that the incidence of fungal infection is increasing in low-risk patients. The BDG assay is still an effective tool used to diagnose invasive fungal diseases. Caspofungin is an effective drug for the treatment of some unknown fungal infections.
Url:
DOI: 10.1097/MD.0000000000016908
PubMed: 31415438
PubMed Central: 6831448
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Yu Ye<affiliation><nlm:aff id="aff3">MRI room, Central Hospital, Huangshi City, Huangshi</nlm:aff>
<wicri:noCountry code="subfield">Huangshi</wicri:noCountry>
</affiliation>
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<front><div type="abstract" xml:lang="en"><title>Abstract</title>
<sec><title>Rationale:</title>
<p>Fungal infectious disease does not usually occur in low-risk patients. Clinicians tend to ignore the role of fungi in the fevers of low-risk patients. If there is not timely control of fungal infections and associated fever, the disease will continue to worsen, resulting in physical dysfunction or death.</p>
</sec>
<sec><title>Patient concerns:</title>
<p>Recurrent fever continued for 1 month in a young adult.</p>
</sec>
<sec><title>Diagnoses and interventions:</title>
<p>Non-albicans Candida (NAC) species probably was the main pathogen in this case based on the resolution of fever after capsofungin administration.</p>
</sec>
<sec><title>Outcomes:</title>
<p>The fever and the associated indicators, including white blood cell count, C-reaction protein, erythrocyte sedimentation rate, and BDG levels, showed improvement quickly. The patient left the hospital successfully after 18 days of caspofungin treatment. There was no recurrent fever at a follow-up of 1 year.</p>
</sec>
<sec><title>Lessons:</title>
<p>Clinicians should be aware that the incidence of fungal infection is increasing in low-risk patients. The BDG assay is still an effective tool used to diagnose invasive fungal diseases. Caspofungin is an effective drug for the treatment of some unknown fungal infections.</p>
</sec>
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