Early Initiation of Steroid-sparing Drugs in Idiopathic Pulmonary Hemosiderosis.
Identifieur interne : 000500 ( Ncbi/Curation ); précédent : 000499; suivant : 000501Early Initiation of Steroid-sparing Drugs in Idiopathic Pulmonary Hemosiderosis.
Auteurs : Priyankar Pal [Inde] ; Hriday De [Inde] ; Prabhas Prasun Giri [Inde] ; Nupur Ganguly [Inde] ; Alolika Mandal [Inde]Source :
- Indian pediatrics [ 0974-7559 ] ; 2019.
Descripteurs français
- KwdFr :
- MESH :
- traitement médicamenteux : Hémosidérose, Maladies pulmonaires.
- usage thérapeutique : Azathioprine, Hydroxychloroquine, Immunosuppresseurs.
- Délai jusqu'au traitement, Enfant, Humains.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Azathioprine, Hydroxychloroquine, Immunosuppressive Agents.
- drug therapy : Hemosiderosis, Lung Diseases.
- Child, Humans, Time-to-Treatment.
Abstract
Idiopathic pulmonary hemosiderosis is conventionally treated with steroids, prolonged usage of which maybe deleterious and disease often recurs on tapering. We initiated hydroxy-chloroquine and azathioprine early in treatment along with steroids in seven children with idiopathic pulmonary hemosiderosis, and observed that early introduction of second line immunosuppressants helped in reducing disease flare and steroid toxicity without serious adverse effects.
PubMed: 30806370
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pubmed:30806370Le document en format XML
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<series><title level="j">Indian pediatrics</title>
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<front><div type="abstract" xml:lang="en">Idiopathic pulmonary hemosiderosis is conventionally treated with steroids, prolonged usage of which maybe deleterious and disease often recurs on tapering. We initiated hydroxy-chloroquine and azathioprine early in treatment along with steroids in seven children with idiopathic pulmonary hemosiderosis, and observed that early introduction of second line immunosuppressants helped in reducing disease flare and steroid toxicity without serious adverse effects.</div>
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