ChloroquineV1, PubMed, Corpus, bibRecord, 000062

Early Initiation of Steroid-sparing Drugs in Idiopathic Pulmonary Hemosiderosis.

Identifieur interne : 000062 ( PubMed/Corpus ); précédent : 000061; suivant : 000063

Early Initiation of Steroid-sparing Drugs in Idiopathic Pulmonary Hemosiderosis.

Auteurs : Priyankar Pal ; Hriday De ; Prabhas Prasun Giri ; Nupur Ganguly ; Alolika Mandal

Source :

Indian pediatrics [ 0974-7559 ] ; 2019.

RBID : pubmed:30806370

English descriptors

KwdEn :
- Azathioprine (therapeutic use), Child, Hemosiderosis (drug therapy), Humans, Hydroxychloroquine (therapeutic use), Immunosuppressive Agents (therapeutic use), Lung Diseases (drug therapy), Time-to-Treatment.
MESH :
- chemical , therapeutic use : Azathioprine, Hydroxychloroquine, Immunosuppressive Agents.
- drug therapy : Hemosiderosis, Lung Diseases.
- Child, Humans, Time-to-Treatment.

Abstract

Idiopathic pulmonary hemosiderosis is conventionally treated with steroids, prolonged usage of which maybe deleterious and disease often recurs on tapering. We initiated hydroxy-chloroquine and azathioprine early in treatment along with steroids in seven children with idiopathic pulmonary hemosiderosis, and observed that early introduction of second line immunosuppressants helped in reducing disease flare and steroid toxicity without serious adverse effects.

PubMed: 30806370

Links to Exploration step

pubmed:30806370

Le document en format XML

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<author><name sortKey="Pal, Priyankar" sort="Pal, Priyankar" uniqKey="Pal P" first="Priyankar" last="Pal">Priyankar Pal</name>
<affiliation><nlm:affiliation>Department of Pediatrics, Institute of Child Health, Kolkata, West Bengal, India. mailme.priyankar@gmail.com.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="De, Hriday" sort="De, Hriday" uniqKey="De H" first="Hriday" last="De">Hriday De</name>
<affiliation><nlm:affiliation>Department of Pediatrics, Institute of Child Health, Kolkata, West Bengal, India.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Giri, Prabhas Prasun" sort="Giri, Prabhas Prasun" uniqKey="Giri P" first="Prabhas Prasun" last="Giri">Prabhas Prasun Giri</name>
<affiliation><nlm:affiliation>Department of Pediatrics, Institute of Child Health, Kolkata, West Bengal, India.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ganguly, Nupur" sort="Ganguly, Nupur" uniqKey="Ganguly N" first="Nupur" last="Ganguly">Nupur Ganguly</name>
<affiliation><nlm:affiliation>Department of Pediatrics, Institute of Child Health, Kolkata, West Bengal, India.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mandal, Alolika" sort="Mandal, Alolika" uniqKey="Mandal A" first="Alolika" last="Mandal">Alolika Mandal</name>
<affiliation><nlm:affiliation>Department of Pediatrics, Institute of Child Health, Kolkata, West Bengal, India.</nlm:affiliation>
</affiliation>
</author>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Early Initiation of Steroid-sparing Drugs in Idiopathic Pulmonary Hemosiderosis.</title>
<author><name sortKey="Pal, Priyankar" sort="Pal, Priyankar" uniqKey="Pal P" first="Priyankar" last="Pal">Priyankar Pal</name>
<affiliation><nlm:affiliation>Department of Pediatrics, Institute of Child Health, Kolkata, West Bengal, India. mailme.priyankar@gmail.com.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="De, Hriday" sort="De, Hriday" uniqKey="De H" first="Hriday" last="De">Hriday De</name>
<affiliation><nlm:affiliation>Department of Pediatrics, Institute of Child Health, Kolkata, West Bengal, India.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Giri, Prabhas Prasun" sort="Giri, Prabhas Prasun" uniqKey="Giri P" first="Prabhas Prasun" last="Giri">Prabhas Prasun Giri</name>
<affiliation><nlm:affiliation>Department of Pediatrics, Institute of Child Health, Kolkata, West Bengal, India.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ganguly, Nupur" sort="Ganguly, Nupur" uniqKey="Ganguly N" first="Nupur" last="Ganguly">Nupur Ganguly</name>
<affiliation><nlm:affiliation>Department of Pediatrics, Institute of Child Health, Kolkata, West Bengal, India.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mandal, Alolika" sort="Mandal, Alolika" uniqKey="Mandal A" first="Alolika" last="Mandal">Alolika Mandal</name>
<affiliation><nlm:affiliation>Department of Pediatrics, Institute of Child Health, Kolkata, West Bengal, India.</nlm:affiliation>
</affiliation>
</author>
</analytic>
<series><title level="j">Indian pediatrics</title>
<idno type="eISSN">0974-7559</idno>
<imprint><date when="2019" type="published">2019</date>
</imprint>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Azathioprine (therapeutic use)</term>
<term>Child</term>
<term>Hemosiderosis (drug therapy)</term>
<term>Humans</term>
<term>Hydroxychloroquine (therapeutic use)</term>
<term>Immunosuppressive Agents (therapeutic use)</term>
<term>Lung Diseases (drug therapy)</term>
<term>Time-to-Treatment</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Azathioprine</term>
<term>Hydroxychloroquine</term>
<term>Immunosuppressive Agents</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Hemosiderosis</term>
<term>Lung Diseases</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Child</term>
<term>Humans</term>
<term>Time-to-Treatment</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Idiopathic pulmonary hemosiderosis is conventionally treated with steroids, prolonged usage of which maybe deleterious and disease often recurs on tapering. We initiated hydroxy-chloroquine and azathioprine early in treatment along with steroids in seven children with idiopathic pulmonary hemosiderosis, and observed that early introduction of second line immunosuppressants helped in reducing disease flare and steroid toxicity without serious adverse effects.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">30806370</PMID>
<DateCompleted><Year>2019</Year>
<Month>08</Month>
<Day>05</Day>
</DateCompleted>
<DateRevised><Year>2019</Year>
<Month>08</Month>
<Day>05</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">0974-7559</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>56</Volume>
<Issue>1</Issue>
<PubDate><Year>2019</Year>
<Month>01</Month>
<Day>15</Day>
</PubDate>
</JournalIssue>
<Title>Indian pediatrics</Title>
<ISOAbbreviation>Indian Pediatr</ISOAbbreviation>
</Journal>
<ArticleTitle>Early Initiation of Steroid-sparing Drugs in Idiopathic Pulmonary Hemosiderosis.</ArticleTitle>
<Pagination><MedlinePgn>73-74</MedlinePgn>
</Pagination>
<Abstract><AbstractText>Idiopathic pulmonary hemosiderosis is conventionally treated with steroids, prolonged usage of which maybe deleterious and disease often recurs on tapering. We initiated hydroxy-chloroquine and azathioprine early in treatment along with steroids in seven children with idiopathic pulmonary hemosiderosis, and observed that early introduction of second line immunosuppressants helped in reducing disease flare and steroid toxicity without serious adverse effects.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Pal</LastName>
<ForeName>Priyankar</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Institute of Child Health, Kolkata, West Bengal, India. mailme.priyankar@gmail.com.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>De</LastName>
<ForeName>Hriday</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Institute of Child Health, Kolkata, West Bengal, India.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Giri</LastName>
<ForeName>Prabhas Prasun</ForeName>
<Initials>PP</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Institute of Child Health, Kolkata, West Bengal, India.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ganguly</LastName>
<ForeName>Nupur</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Institute of Child Health, Kolkata, West Bengal, India.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mandal</LastName>
<ForeName>Alolika</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Institute of Child Health, Kolkata, West Bengal, India.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016422">Letter</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>India</Country>
<MedlineTA>Indian Pediatr</MedlineTA>
<NlmUniqueID>2985062R</NlmUniqueID>
<ISSNLinking>0019-6061</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D007166">Immunosuppressive Agents</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>4QWG6N8QKH</RegistryNumber>
<NameOfSubstance UI="D006886">Hydroxychloroquine</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>MRK240IY2L</RegistryNumber>
<NameOfSubstance UI="D001379">Azathioprine</NameOfSubstance>
</Chemical>
</ChemicalList>
<SupplMeshList><SupplMeshName Type="Disease" UI="C536281">Idiopathic pulmonary hemosiderosis</SupplMeshName>
</SupplMeshList>
<MeshHeadingList><MeshHeading><DescriptorName UI="D001379" MajorTopicYN="N">Azathioprine</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006486" MajorTopicYN="N">Hemosiderosis</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006886" MajorTopicYN="N">Hydroxychloroquine</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007166" MajorTopicYN="N">Immunosuppressive Agents</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008171" MajorTopicYN="N">Lung Diseases</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D061665" MajorTopicYN="N">Time-to-Treatment</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2019</Year>
<Month>2</Month>
<Day>27</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2019</Year>
<Month>2</Month>
<Day>27</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<PubMedPubDate PubStatus="medline"><Year>2019</Year>
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<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">30806370</ArticleId>
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Early Initiation of Steroid-sparing Drugs in Idiopathic Pulmonary Hemosiderosis.

Early Initiation of Steroid-sparing Drugs in Idiopathic Pulmonary Hemosiderosis.

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki