Mefloquine-induced pneumonitis.
Identifieur interne : 004099 ( Main/Merge ); précédent : 004098; suivant : 004100Mefloquine-induced pneumonitis.
Auteurs : Patrick Soentjens [Belgique] ; Marc Delanote ; Alfons Van GompelSource :
- Journal of travel medicine [ 1195-1982 ]
Descripteurs français
- KwdFr :
- MESH :
- administration et posologie : Antipaludiques, Méfloquine.
- diagnostic : Pneumopathie infectieuse.
- effets indésirables : Antipaludiques, Méfloquine.
- Adulte d'âge moyen, Femelle, Humains, Paludisme, Pneumopathie infectieuse.
English descriptors
- KwdEn :
- MESH :
- chemical , administration & dosage : Antimalarials, Mefloquine.
- chemical , adverse effects : Antimalarials, Mefloquine.
- chemically induced : Pneumonia.
- diagnosis : Pneumonia.
- prevention & control : Malaria.
- Female, Humans, Middle Aged.
Abstract
Mefloquine is indicated as oral treatment and as prophylaxis for malaria in areas where chloroquine-resistant malaria is present. Gastrointestinal and neuropsychiatric side effects of mefloquine are well known. More severe neuropsychiatric disorders such as psychosis, depression, hallucinations, and seizures are also reported in the literature. We are reporting a case of drug-induced pneumonia due to mefloquine. This diagnosis was confirmed 4 months after the adverse event, after restarting the same malaria prophylaxis, which could be considered as an unintentional provocation test. This is the third case report in the literature of acute lung injury caused by mefloquine.
DOI: 10.1111/j.1708-8305.2006.00037.x
PubMed: 16706949
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pubmed:16706949Le document en format XML
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antimalarials (administration & dosage)</term>
<term>Antimalarials (adverse effects)</term>
<term>Female</term>
<term>Humans</term>
<term>Malaria (prevention & control)</term>
<term>Mefloquine (administration & dosage)</term>
<term>Mefloquine (adverse effects)</term>
<term>Middle Aged</term>
<term>Pneumonia (chemically induced)</term>
<term>Pneumonia (diagnosis)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Antipaludiques (administration et posologie)</term>
<term>Antipaludiques (effets indésirables)</term>
<term>Femelle</term>
<term>Humains</term>
<term>Méfloquine (administration et posologie)</term>
<term>Méfloquine (effets indésirables)</term>
<term>Paludisme ()</term>
<term>Pneumopathie infectieuse ()</term>
<term>Pneumopathie infectieuse (diagnostic)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Antimalarials</term>
<term>Mefloquine</term>
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<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Antimalarials</term>
<term>Mefloquine</term>
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<keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Antipaludiques</term>
<term>Méfloquine</term>
</keywords>
<keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Pneumonia</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Pneumonia</term>
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<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Pneumopathie infectieuse</term>
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<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Antipaludiques</term>
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<term>Middle Aged</term>
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<term>Humains</term>
<term>Paludisme</term>
<term>Pneumopathie infectieuse</term>
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<front><div type="abstract" xml:lang="en">Mefloquine is indicated as oral treatment and as prophylaxis for malaria in areas where chloroquine-resistant malaria is present. Gastrointestinal and neuropsychiatric side effects of mefloquine are well known. More severe neuropsychiatric disorders such as psychosis, depression, hallucinations, and seizures are also reported in the literature. We are reporting a case of drug-induced pneumonia due to mefloquine. This diagnosis was confirmed 4 months after the adverse event, after restarting the same malaria prophylaxis, which could be considered as an unintentional provocation test. This is the third case report in the literature of acute lung injury caused by mefloquine.</div>
</front>
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