Marine Pharmacology in 2014–2015: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis, Antiviral, and Anthelmintic Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action
Identifieur interne : 000651 ( Main/Merge ); précédent : 000650; suivant : 000652Marine Pharmacology in 2014–2015: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis, Antiviral, and Anthelmintic Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action
Auteurs : Alejandro M. S. Mayer ; Aimee J. Guerrero ; Abimael D. Rodríguez ; Orazio Taglialatela-Scafati ; Fumiaki Nakamura ; Nobuhiro FusetaniSource :
- Marine Drugs [ 1660-3397 ] ; 2019.
Abstract
The systematic review of the marine pharmacology literature from 2014 to 2015 was completed in a manner consistent with the 1998–2013 reviews of this series. Research in marine pharmacology during 2014–2015, which was reported by investigators in 43 countries, described novel findings on the preclinical pharmacology of 301 marine compounds. These observations included antibacterial, antifungal, antiprotozoal, antituberculosis, antiviral, and anthelmintic pharmacological activities for 133 marine natural products, 85 marine compounds with antidiabetic, and anti-inflammatory activities, as well as those that affected the immune and nervous system, and 83 marine compounds that displayed miscellaneous mechanisms of action, and may probably contribute to novel pharmacological classes upon further research. Thus, in 2014–2015, the
Url:
DOI: 10.3390/md18010005
PubMed: 31861527
PubMed Central: 7024264
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PMC:7024264Le document en format XML
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Marine Pharmacology in 2014–2015: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis, Antiviral, and Anthelmintic Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action</title>
<author><name sortKey="Mayer, Alejandro M S" sort="Mayer, Alejandro M S" uniqKey="Mayer A" first="Alejandro M. S." last="Mayer">Alejandro M. S. Mayer</name>
<affiliation><nlm:aff id="af1-marinedrugs-18-00005">Department of Pharmacology, College of Graduate Studies, Midwestern University, 555 31st Street, Downers Grove, IL 60515, USA;<email>aguerrero89@midwestern.edu</email>
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<author><name sortKey="Guerrero, Aimee J" sort="Guerrero, Aimee J" uniqKey="Guerrero A" first="Aimee J." last="Guerrero">Aimee J. Guerrero</name>
<affiliation><nlm:aff id="af1-marinedrugs-18-00005">Department of Pharmacology, College of Graduate Studies, Midwestern University, 555 31st Street, Downers Grove, IL 60515, USA;<email>aguerrero89@midwestern.edu</email>
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<author><name sortKey="Rodriguez, Abimael D" sort="Rodriguez, Abimael D" uniqKey="Rodriguez A" first="Abimael D." last="Rodríguez">Abimael D. Rodríguez</name>
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<author><name sortKey="Taglialatela Scafati, Orazio" sort="Taglialatela Scafati, Orazio" uniqKey="Taglialatela Scafati O" first="Orazio" last="Taglialatela-Scafati">Orazio Taglialatela-Scafati</name>
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</affiliation>
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<author><name sortKey="Nakamura, Fumiaki" sort="Nakamura, Fumiaki" uniqKey="Nakamura F" first="Fumiaki" last="Nakamura">Fumiaki Nakamura</name>
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<author><name sortKey="Fusetani, Nobuhiro" sort="Fusetani, Nobuhiro" uniqKey="Fusetani N" first="Nobuhiro" last="Fusetani">Nobuhiro Fusetani</name>
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<series><title level="j">Marine Drugs</title>
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<front><div type="abstract" xml:lang="en"><p>The systematic review of the marine pharmacology literature from 2014 to 2015 was completed in a manner consistent with the 1998–2013 reviews of this series. Research in marine pharmacology during 2014–2015, which was reported by investigators in 43 countries, described novel findings on the preclinical pharmacology of 301 marine compounds. These observations included antibacterial, antifungal, antiprotozoal, antituberculosis, antiviral, and anthelmintic pharmacological activities for 133 marine natural products, 85 marine compounds with antidiabetic, and anti-inflammatory activities, as well as those that affected the immune and nervous system, and 83 marine compounds that displayed miscellaneous mechanisms of action, and may probably contribute to novel pharmacological classes upon further research. Thus, in 2014–2015, the <italic>preclinical</italic>
marine natural product pharmacology pipeline provided novel pharmacology as well as new lead compounds for the <italic>clinical</italic>
marine pharmaceutical pipeline, and thus continued to contribute to ongoing global research for alternative therapeutic approaches to many disease categories.</p>
</div>
</front>
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