Cytotoxic agents in sarcoidosis: which one should we choose?
Identifieur interne : 001026 ( Main/Exploration ); précédent : 001025; suivant : 001027Cytotoxic agents in sarcoidosis: which one should we choose?
Auteurs : Adriane D M. Vorselaars ; Johanna P. Cremers ; Jan C. Grutters ; Marjolein DrentSource :
- Current opinion in pulmonary medicine [ 1531-6971 ] ; 2014.
Descripteurs français
- KwdFr :
- MESH :
- antagonistes et inhibiteurs : Facteur de nécrose tumorale alpha.
- traitement médicamenteux : Sarcoïdose.
- usage thérapeutique : Cytotoxines, Immunosuppresseurs.
- Humains.
English descriptors
- KwdEn :
- MESH :
- chemical , antagonists & inhibitors : Tumor Necrosis Factor-alpha.
- chemical , therapeutic use : Cytotoxins, Immunosuppressive Agents.
- drug therapy : Sarcoidosis.
- Humans.
Abstract
Sarcoidosis is a granulomatous disease which affects multiple organs. Its therapeutic management is very challenging due to the heterogeneity in disease manifestation and clinical course, as well as the potential side effects of the immunosuppressive therapy. An overview of presently available second-line and third-line systemic agents is provided.
DOI: 10.1097/MCP.0000000000000078
PubMed: 25046427
Affiliations:
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Le document en format XML
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<affiliation><nlm:affiliation>aCentre of Interstitial Lung Diseases, Department of Pulmonology, St Antonius Hospital, Nieuwegein bild care expertise team, Department of Respiratory Medicine, Hospital Gelderse Vallei, Ede cDepartment of Internal Medicine, Atrium Medical Centre, Heerlen dDivision of Heart and Lungs, University Medical Centre Utrecht, Utrecht eDepartment of Toxicology, Faculty of Health, Medicine and Life Sciences (FHML), University Maastricht, Maastricht, The Netherlands *Adriane D.M. Vorselaars and Johanna P. Cremers contributed equally to the writing of this article.</nlm:affiliation>
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<term>Tumor Necrosis Factor-alpha (antagonists & inhibitors)</term>
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<term>Facteur de nécrose tumorale alpha (antagonistes et inhibiteurs)</term>
<term>Humains</term>
<term>Immunosuppresseurs (usage thérapeutique)</term>
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<front><div type="abstract" xml:lang="en">Sarcoidosis is a granulomatous disease which affects multiple organs. Its therapeutic management is very challenging due to the heterogeneity in disease manifestation and clinical course, as well as the potential side effects of the immunosuppressive therapy. An overview of presently available second-line and third-line systemic agents is provided.</div>
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<name sortKey="Grutters, Jan C" sort="Grutters, Jan C" uniqKey="Grutters J" first="Jan C" last="Grutters">Jan C. Grutters</name>
<name sortKey="Vorselaars, Adriane D M" sort="Vorselaars, Adriane D M" uniqKey="Vorselaars A" first="Adriane D M" last="Vorselaars">Adriane D M. Vorselaars</name>
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