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Dermatomyositis

Identifieur interne : 002828 ( Main/Exploration ); précédent : 002827; suivant : 002829

Dermatomyositis

Auteurs : Stephen O. Kovacs [États-Unis] ; S. Christine Kovacs [États-Unis]

Source :

RBID : ISTEX:4916D3FAB6BBB355FB31A35B1B2564D631C4747E

English descriptors

Abstract

Abstract: Dermatomyositis is a rare inflammatory myopathy with characteristic skin manifestations and muscular weakness. The disease can be categorized as adult idiopathic, juvenile, or amyopathic dermatomyositis as well as that associated with a connective tissue disease or a malignancy. Immunologic factors are most likely involved in the pathogenesis of the disease; however, genetic and environmental issues may also play important roles. Treatment with immunosuppressive agents has proved successful in the majority of patients, although significant morbidity still occurs. (J Am Acad Dermatol 1998;39:899-920.) Learning Objective: At the conclusion of this learning activity, participants should be familiar with the clinical characteristics of adult idiopathic, juvenile, and amyopathic dermatomyositis as well as the histopathologic and immunopathologic characteristics of the disease.

Url:
DOI: 10.1016/S0190-9622(98)70263-4


Affiliations:


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Le document en format XML

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<term>Acad dermatol</term>
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<term>Amyopathic</term>
<term>Amyopathic dermatomyositis</term>
<term>Arthritis</term>
<term>Arthritis rheum</term>
<term>Autoantibody</term>
<term>Azathioprine</term>
<term>Calcinosis</term>
<term>Calcinosis cutis</term>
<term>Callen</term>
<term>Clin</term>
<term>Connective tissue disease</term>
<term>Corticosteroid</term>
<term>Creatine</term>
<term>Curr</term>
<term>Cutaneous</term>
<term>Cutis</term>
<term>Cyclophosphamide</term>
<term>Dalakas</term>
<term>December</term>
<term>Dermatol</term>
<term>Dermatology</term>
<term>Dermatology december</term>
<term>Dermatology volume</term>
<term>Dermatomyositis</term>
<term>Engel</term>
<term>Engl</term>
<term>Erythematosus</term>
<term>Histopathologic</term>
<term>Hydroxychloroquine</term>
<term>Idiopathic</term>
<term>Immunoglobulin</term>
<term>Inflammatory</term>
<term>Inflammatory myopathies</term>
<term>Inflammatory myopathy</term>
<term>Intravenous</term>
<term>Juvenile dermatomyositis</term>
<term>Kovacs</term>
<term>Lancet</term>
<term>Lupus</term>
<term>Lymphocyte</term>
<term>Malignancy</term>
<term>Medsger</term>
<term>Methotrexate</term>
<term>Muscle weakness</term>
<term>Myalgia</term>
<term>Myopathy</term>
<term>Myositis</term>
<term>Neurol</term>
<term>Opin</term>
<term>Pachman</term>
<term>Pathol</term>
<term>Pediatr</term>
<term>Periorbital</term>
<term>Polymyositis</term>
<term>Rash</term>
<term>Rheum</term>
<term>Rheumatoid</term>
<term>Rheumatol</term>
<term>Scleroderma</term>
<term>Skin manifestations</term>
<term>Steroid</term>
<term>Syndrome</term>
<term>Synthetase</term>
<term>Systemic lupus erythematosus</term>
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<div type="abstract" xml:lang="en">Abstract: Dermatomyositis is a rare inflammatory myopathy with characteristic skin manifestations and muscular weakness. The disease can be categorized as adult idiopathic, juvenile, or amyopathic dermatomyositis as well as that associated with a connective tissue disease or a malignancy. Immunologic factors are most likely involved in the pathogenesis of the disease; however, genetic and environmental issues may also play important roles. Treatment with immunosuppressive agents has proved successful in the majority of patients, although significant morbidity still occurs. (J Am Acad Dermatol 1998;39:899-920.) Learning Objective: At the conclusion of this learning activity, participants should be familiar with the clinical characteristics of adult idiopathic, juvenile, and amyopathic dermatomyositis as well as the histopathologic and immunopathologic characteristics of the disease.</div>
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