[Osteoarticular sarcoidosis].
Identifieur interne : 002716 ( Main/Exploration ); précédent : 002715; suivant : 002717[Osteoarticular sarcoidosis].
Auteurs : M. MarvisiSource :
- Minerva medica [ 0026-4806 ] ; 1998.
Descripteurs français
- KwdFr :
- Adulte, Analgésiques (usage thérapeutique), Antirhumatismaux (usage thérapeutique), Biopsie, Chloroquine (usage thérapeutique), Diagnostic différentiel, Enfant, Femelle, Hormones corticosurrénaliennes (usage thérapeutique), Humains, Hydroxychloroquine (usage thérapeutique), Imagerie par résonance magnétique, Maladies articulaires (diagnostic), Maladies articulaires (traitement médicamenteux), Maladies osseuses (diagnostic), Maladies osseuses (traitement médicamenteux), Mâle, Peptidyl-Dipeptidase A (sang), Sarcoïdose (diagnostic), Sarcoïdose (traitement médicamenteux), Tests enzymatiques en clinique, Tomodensitométrie.
- MESH :
- diagnostic : Maladies articulaires, Maladies osseuses, Sarcoïdose.
- sang : Peptidyl-Dipeptidase A.
- traitement médicamenteux : Maladies articulaires, Maladies osseuses, Sarcoïdose.
- usage thérapeutique : Analgésiques, Antirhumatismaux, Chloroquine, Hormones corticosurrénaliennes, Hydroxychloroquine.
- Adulte, Biopsie, Diagnostic différentiel, Enfant, Femelle, Humains, Imagerie par résonance magnétique, Mâle, Tests enzymatiques en clinique, Tomodensitométrie.
English descriptors
- KwdEn :
- Adrenal Cortex Hormones (therapeutic use), Adult, Analgesics (therapeutic use), Antirheumatic Agents (therapeutic use), Biopsy, Bone Diseases (diagnosis), Bone Diseases (drug therapy), Child, Chloroquine (therapeutic use), Clinical Enzyme Tests, Diagnosis, Differential, Female, Humans, Hydroxychloroquine (therapeutic use), Joint Diseases (diagnosis), Joint Diseases (drug therapy), Magnetic Resonance Imaging, Male, Peptidyl-Dipeptidase A (blood), Sarcoidosis (diagnosis), Sarcoidosis (drug therapy), Tomography, X-Ray Computed.
- MESH :
- chemical , blood : Peptidyl-Dipeptidase A.
- chemical , therapeutic use : Adrenal Cortex Hormones, Analgesics, Antirheumatic Agents, Chloroquine, Hydroxychloroquine.
- diagnosis : Bone Diseases, Joint Diseases, Sarcoidosis.
- drug therapy : Bone Diseases, Joint Diseases, Sarcoidosis.
- Adult, Biopsy, Child, Clinical Enzyme Tests, Diagnosis, Differential, Female, Humans, Magnetic Resonance Imaging, Male, Tomography, X-Ray Computed.
Abstract
Sarcoidosis (S) is a systemic disease affecting above all lymph nodes and lung tissue. Skeletal involvement is reported to occur in 14% of patients, the most common manifestations is cystoid osteitis, an asymptomatic lesion localized to the small bones of hand and feet. Lytic lesions are rare and usually accompanied by visceral involvement, the lesions may be detected in vertebral bodies and in long bones, pelvis and scapulae. MRI may be a good diagnostic tool, but open biopsy is often necessary. Joints are involved in about 89% of patients with acute sarcoidosis. Arthritis is localized more frequently to knees and ankles, is polyarticular, a little painful, migratory and transient, often accompanied by erythema nodosum. Clinical manifestations disappear in a few weeks, chronic and erosive disease is rare and always associated with systemic involvement. In these patients it may be useful to perform gallium citrate 67 scintigram and evaluation of serum ACE. Synovial biopsy lacks of specificity and sensibility, and in some cases it is necessary to perform open biopsy. S is a disease that may spontaneously regress and therapy may be unnecessary. In some cases, methotrexate may be useful in addition to prednisone. Chloroquine and hydroxychloroquine are effective in cases of skeletal involvement.
PubMed: 9676182
Affiliations:
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Le document en format XML
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<series><title level="j">Minerva medica</title>
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<term>Antirheumatic Agents (therapeutic use)</term>
<term>Biopsy</term>
<term>Bone Diseases (diagnosis)</term>
<term>Bone Diseases (drug therapy)</term>
<term>Child</term>
<term>Chloroquine (therapeutic use)</term>
<term>Clinical Enzyme Tests</term>
<term>Diagnosis, Differential</term>
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<term>Humans</term>
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<term>Joint Diseases (drug therapy)</term>
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<term>Tomography, X-Ray Computed</term>
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<term>Analgésiques (usage thérapeutique)</term>
<term>Antirhumatismaux (usage thérapeutique)</term>
<term>Biopsie</term>
<term>Chloroquine (usage thérapeutique)</term>
<term>Diagnostic différentiel</term>
<term>Enfant</term>
<term>Femelle</term>
<term>Hormones corticosurrénaliennes (usage thérapeutique)</term>
<term>Humains</term>
<term>Hydroxychloroquine (usage thérapeutique)</term>
<term>Imagerie par résonance magnétique</term>
<term>Maladies articulaires (diagnostic)</term>
<term>Maladies articulaires (traitement médicamenteux)</term>
<term>Maladies osseuses (diagnostic)</term>
<term>Maladies osseuses (traitement médicamenteux)</term>
<term>Mâle</term>
<term>Peptidyl-Dipeptidase A (sang)</term>
<term>Sarcoïdose (diagnostic)</term>
<term>Sarcoïdose (traitement médicamenteux)</term>
<term>Tests enzymatiques en clinique</term>
<term>Tomodensitométrie</term>
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<term>Antirheumatic Agents</term>
<term>Chloroquine</term>
<term>Hydroxychloroquine</term>
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<term>Sarcoidosis</term>
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<term>Maladies osseuses</term>
<term>Sarcoïdose</term>
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<term>Joint Diseases</term>
<term>Sarcoidosis</term>
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<term>Maladies osseuses</term>
<term>Sarcoïdose</term>
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<term>Antirhumatismaux</term>
<term>Chloroquine</term>
<term>Hormones corticosurrénaliennes</term>
<term>Hydroxychloroquine</term>
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<term>Biopsy</term>
<term>Child</term>
<term>Clinical Enzyme Tests</term>
<term>Diagnosis, Differential</term>
<term>Female</term>
<term>Humans</term>
<term>Magnetic Resonance Imaging</term>
<term>Male</term>
<term>Tomography, X-Ray Computed</term>
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<term>Biopsie</term>
<term>Diagnostic différentiel</term>
<term>Enfant</term>
<term>Femelle</term>
<term>Humains</term>
<term>Imagerie par résonance magnétique</term>
<term>Mâle</term>
<term>Tests enzymatiques en clinique</term>
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<front><div type="abstract" xml:lang="en">Sarcoidosis (S) is a systemic disease affecting above all lymph nodes and lung tissue. Skeletal involvement is reported to occur in 14% of patients, the most common manifestations is cystoid osteitis, an asymptomatic lesion localized to the small bones of hand and feet. Lytic lesions are rare and usually accompanied by visceral involvement, the lesions may be detected in vertebral bodies and in long bones, pelvis and scapulae. MRI may be a good diagnostic tool, but open biopsy is often necessary. Joints are involved in about 89% of patients with acute sarcoidosis. Arthritis is localized more frequently to knees and ankles, is polyarticular, a little painful, migratory and transient, often accompanied by erythema nodosum. Clinical manifestations disappear in a few weeks, chronic and erosive disease is rare and always associated with systemic involvement. In these patients it may be useful to perform gallium citrate 67 scintigram and evaluation of serum ACE. Synovial biopsy lacks of specificity and sensibility, and in some cases it is necessary to perform open biopsy. S is a disease that may spontaneously regress and therapy may be unnecessary. In some cases, methotrexate may be useful in addition to prednisone. Chloroquine and hydroxychloroquine are effective in cases of skeletal involvement.</div>
</front>
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