ChloroquineV1, Main, Exploration, bibRecord, 002035

Sex ratios in the rodent malaria parasite, Plasmodium chabaudi

Identifieur interne : 002035 ( Main/Exploration ); précédent : 002034; suivant : 002036

Sex ratios in the rodent malaria parasite, Plasmodium chabaudi

Auteurs : S. E. Reece [Royaume-Uni] ; A. Duncan [Royaume-Uni] ; S. A. West [Royaume-Uni] ; A. F. Read [Royaume-Uni]

Source :

Parasitology [ 0031-1820 ] ; 2003.

RBID : Hal:hal-02353129

English descriptors

mix :
- blood smears, gametocyte, mortality, sex allocation theory.

Abstract

The sex ratios of malaria and related Apicomplexan parasites play a major role in transmission success. Here, we address 2 fundamental issues in the sex ratios of the rodent malaria parasite, Plasmodium chabaudi. First we test the accuracy of empirical methods for estimating sex ratios in malaria parasites, and show that sex ratios made with standard thin smears may overestimate the proportion of female gametocytes. Secondly, we test whether the mortality rate differs between male and female gametocytes, as assumed by sex ratio theory. Conventional application of sex ratio theory to malaria parasites assumes that the primary sex ratio can be accurately determined from mature gametocytes circulating in the peripheral circulation. We stopped gametocyte production with chloroquine in order to study a cohort of gametocytes in vitro. The mortality rate was significantly higher for female gametocytes, with an average half-life of 8 h for female gametocytes and 16 h for male gametocytes.

Url:

https://hal.archives-ouvertes.fr/hal-02353129

DOI: 10.1017/S0031182003004013

Affiliations:

Royaume-Uni

Links toward previous steps (curation, corpus...)

to stream Hal, to step Corpus: 000214
to stream Hal, to step Curation: 000214
to stream Hal, to step Checkpoint: 000246
to stream Main, to step Merge: 002051
to stream Main, to step Curation: 002035

Le document en format XML

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<front><div type="abstract" xml:lang="en">              <p>The sex ratios of malaria and related Apicomplexan parasites play a major role in transmission success. Here, we address 2 fundamental issues in the sex ratios of the rodent malaria parasite, Plasmodium chabaudi. First we test the accuracy of empirical methods for estimating sex ratios in malaria parasites, and show that sex ratios made with standard thin smears may overestimate the proportion of female gametocytes. Secondly, we test whether the mortality rate differs between male and female gametocytes, as assumed by sex ratio theory. Conventional application of sex ratio theory to malaria parasites assumes that the primary sex ratio can be accurately determined from mature gametocytes circulating in the peripheral circulation. We stopped gametocyte production with chloroquine in order to study a cohort of gametocytes in vitro. The mortality rate was significantly higher for female gametocytes, with an average half-life of 8 h for female gametocytes and 16 h for male gametocytes.</p>
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Sex ratios in the rodent malaria parasite, Plasmodium chabaudi

Sex ratios in the rodent malaria parasite, Plasmodium chabaudi

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri