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Pregnancy in rare autoimmune rheumatic diseases: UCTD, MCTD, myositis, systemic vasculitis and Beçhet disease

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Pregnancy in rare autoimmune rheumatic diseases: UCTD, MCTD, myositis, systemic vasculitis and Beçhet disease

Auteurs : A. Doria [Italie] ; L. Iaccarino [Italie] ; A. Ghirardello [Italie] ; C. Briani [Italie] ; S. Zampieri [Italie] ; E. Tarricone [Italie] ; P F Gambari [Italie]

Source :

Lupus [ 0961-2033 ] ; 2004-09.

RBID : ISTEX:44C077AA4359798F3E70E9200F1C16730B016C3D

English descriptors

Teeft :
- Active disease, Arch intern, Arthritis rheum, Bechet disease, Case report, Case reports, Childhood onset, Clinical course, Clinical features, Connective tissue disease, Connective tissue diseases, Dermatomyositis, Disease activity, Disease duration, Disease manifestations, Disease onset, Disease relapse, Disease remission, Doria, Foetal, Foetal loss, Foetal outcome, Genital ulcers, Granulomatosis, Granulomatosus vasculitis, Gynecol, Heart block, High dose, High frequency, High risk, Large cohort, Late pregnancy, Literature review, Lupus, Maternal complications, Maternal death, Microscopic polyangiitis, Mononeuritis multiplex, Mosca, Multidisciplinary team, Neonatal complications, Nephrol dial transplant, Obstet, Obstet gynecol, Other vasculitis, Plasma exchange, Polyarteritis nodosa, Polymyositis, Postpartum, Pregnancy, Pregnancy loss, Pregnancy outcome, Pregnant patients, Premature delivery, Prospective study, Relapse, Rheum, Rheumatic diseases, Rheumatol, Skin rash, Such diseases, Systemic, Systemic lupus erythematosus, Systemic vasculitis, Takayasu arteritis, Term births, Therapeutic abortion, Third trimester, Tissue disease, Tissue diseases, Twin pregnancy, Uctd, Undifferentiated, Vasculitis.

Abstract

The physiological adaptation of the immune system to pregnancy can potentially affect the course of all autoimmune rheumatic diseases (ARD), conversely the autoimmune processes characteristic of these conditions may compromise the foetal outcome. Unfortunately, very few reports on pregnancy outcome in patients with rare ARD are available. In this paper, we briefly review the data published until now on these disorders. Some general guidelines which were elaborated for more prevalent ARD seem to be valid also for such rare conditions: 1) patients should be correctly informed on the risk of becoming pregnant; 2) pregnancies should be planned when the disease is in remission since it increases the probability of successful maternal and foetal outcome; 3) patients should be regularly monitored during gestation and postpartum by a multidisciplinary team including rheumatologist, obstetrician, and neonatologist; 4) in the case of disease relapse an adequate treatment, even aggressive if necessary, should be recommended since active disease can be more detrimental for foetus than drugs; 5) pregnancies complicated by the onset of rare ARD have a particularly severe prognosis; in these cases a prompt treatment and very close clinical surveillance are indicated.

Url:

https://api.istex.fr/ark:/67375/M70-837XSC5M-H/fulltext.pdf

DOI: 10.1191/0961203304lu1098oa

Affiliations:

Italie

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Le document en format XML

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<term>Case reports</term>
<term>Childhood onset</term>
<term>Clinical course</term>
<term>Clinical features</term>
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<term>Connective tissue diseases</term>
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<front><div type="abstract" xml:lang="en">The physiological adaptation of the immune system to pregnancy can potentially affect the course of all autoimmune rheumatic diseases (ARD), conversely the autoimmune processes characteristic of these conditions may compromise the foetal outcome. Unfortunately, very few reports on pregnancy outcome in patients with rare ARD are available. In this paper, we briefly review the data published until now on these disorders. Some general guidelines which were elaborated for more prevalent ARD seem to be valid also for such rare conditions: 1) patients should be correctly informed on the risk of becoming pregnant; 2) pregnancies should be planned when the disease is in remission since it increases the probability of successful maternal and foetal outcome; 3) patients should be regularly monitored during gestation and postpartum by a multidisciplinary team including rheumatologist, obstetrician, and neonatologist; 4) in the case of disease relapse an adequate treatment, even aggressive if necessary, should be recommended since active disease can be more detrimental for foetus than drugs; 5) pregnancies complicated by the onset of rare ARD have a particularly severe prognosis; in these cases a prompt treatment and very close clinical surveillance are indicated.</div>
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Pregnancy in rare autoimmune rheumatic diseases: UCTD, MCTD, myositis, systemic vasculitis and Beçhet disease

Pregnancy in rare autoimmune rheumatic diseases: UCTD, MCTD, myositis, systemic vasculitis and Beçhet disease

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri