The importance of tobacco in cardiovascular pathology has been underlined in epidemiological studies. Surprisingly, lifestyle counseling for hypertensive patients (JNC 7 and ESH 03) mentions the cessation of the smoking habit as a means of decreasing cardiovascular risk, forgetting its impact over blood pressure control. 1- To classify a population of high cardiovascular risk (HCVR) according with their smoking habit. 2- To study their correlation with anthropometric, hemodynamic and lipid metabolism variables. N = 181, aged 21–87, 91 m, 90 f, with HCVR, defined by DM or at least 2 CVR factors (family history, male gender, smoking, hypertension, dyslipemia, hyperhomocysteinemia, high lipoprotein (a) levels) Smoking habit: Non-smoker (NSm), Ex-smoker (ESm) (> 3 months without smoking), Smoker (Sm) (at least 5 cig/day) BMI (Kg/m2), waist circumference (cm). Total cholesterol, HDL, LDL, triglycerides (TG) (mg/dl) (Hitachi) 24-hour ambulatory blood pressure monitoring (ABPM): Spacelabs 90207. Average SBP, aDBP, aBP Mean (BPM) (SBP-DBP + DBP/3). Standard S and D BP Burden (S>125 and D>75 mmHg reading percentages (SSBPB and SDBPB). Hemodynamic Load (HL=Heart Rate × BPM/100). SBP variability (SBPV) and DBP variability (DBPV) Statistical analysis: t-Student. 1 - N=106 (55.5%) NSm; N=47 (25.9%) ESm; and N=28 (15.46%) Sm. 2 - The Sm patient group was youngest and had lower BMI (p=0.04) 3 - Whilst comparing Sm and NSm groups, the following significant differences were observed: average SBP (p=0.03), SDBPB (p=0.02), TG (p=0.02). 4 – Whilst comparing Sm and ESm groups, the following significant differences were observed: SDBPB (p <0.05), DBPm (p<0.02), HL (p=0.034), with the most unfavorable results in the smoking group. 5 – No differences were observed between the non-smoker and ex-smoker patient groups. 1 - The smoking habit is correlated with different hemodynamic and lipid parameters. 2 - The above-mentioned cannot be attributed to the changes associated neither to age nor to weight because both of these were lower in smokers, adding even greater importance to our findings. 3 - A 3-month period after smoking cessation is enough for the reversion of the hemodynamic alterations. 4 – Nowadays we can add new data to justify the suppression of the smoking habit in patients with high cardiovascular risk. Am J Hypertens (2004) 17, 231A–232A; doi: 10.1016/j.amjhyper.2004.03.618

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   |wiki=    Sante
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   |texte=   P-544: Smoking habit in patients with high cardiovascular risk: the impact on blood pressure after tobacco withdrawal
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