Multiple nail fold nodules in a child
Identifieur interne : 001C97 ( Main/Exploration ); précédent : 001C96; suivant : 001C98Multiple nail fold nodules in a child
Auteurs : B. Tallon ; M. Rademaker ; M. ThorburnSource :
- Australasian Journal of Dermatology [ 0004-8380 ] ; 2006-11.
English descriptors
- Teeft :
- Adelaide, Annual conference, Atypical, Australasian, Biopsy, Carcinoma, Carcinosarcoma, Case series, Cutaneous, Dermatology, Differential diagnosis, Electron microscopy, Extraskeletal osteosarcomas, Fungoides, Genetic results, George hospital, Granulomatous, Histological, Histological features, Histopathological features, Igdr, Interstitial granulomatous drug reaction, Leishmaniasis, Likelihood ratio, Major types, Malignant, Medial, Medial ankle, Metastatic osteosarcoma, Mycosis, Mycosis fungoides, Nodule, Osteosarcoma, Panniculitis, Rare variant, Recurrent tumour, Royal adelaide hospital, Squamous cell carcinoma, Tumour.
Abstract
A case is presented of a 5 year old girl, who over 12 months developed multiple asymptomatic yellow‐brown nodules over the distal digits and nail beds, in association with joint stiffness and swelling. Biopsy of a representative nodule showed a nodular non‐encapsulated dermal histiocytic infiltrate. Within this were scattered multinucleate giant cells with a ground glass eosinophilic cytoplasm consistent with multicentric reticulohistiocytosis (MR). This is a rare subgroup of the non‐Langerhans cell histiocytoses which in contrast to solitary giant cell reticulohistiocytomas, is associated with a destructive arthritis. Typically MR affects Caucasian adults, with paediatric cases being rarely reported. Coeliac antibodies, strongly positive in this case, have only once been described in association with this disease, and may support an autoimmune pathogenesis.
Url:
DOI: 10.1111/j.1440-0960.2006.00311_5.x
Affiliations:
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Thorburn</name></author></analytic><monogr></monogr><series><title level="j" type="main">Australasian Journal of Dermatology</title><title level="j" type="alt">AUSTRALASIAN JOURNAL DERMATOLOGY</title><idno type="ISSN">0004-8380</idno><idno type="eISSN">1440-0960</idno><imprint><biblScope unit="vol">47</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="A58">A58</biblScope><biblScope unit="page" to="A58">A58</biblScope><biblScope unit="page-count">1</biblScope><publisher>Blackwell Publishing Asia</publisher><pubPlace>Melbourne, Australia</pubPlace><date type="published" when="2006-11">2006-11</date></imprint><idno type="ISSN">0004-8380</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0004-8380</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Adelaide</term><term>Annual conference</term><term>Atypical</term><term>Australasian</term><term>Biopsy</term><term>Carcinoma</term><term>Carcinosarcoma</term><term>Case series</term><term>Cutaneous</term><term>Dermatology</term><term>Differential diagnosis</term><term>Electron microscopy</term><term>Extraskeletal osteosarcomas</term><term>Fungoides</term><term>Genetic results</term><term>George hospital</term><term>Granulomatous</term><term>Histological</term><term>Histological features</term><term>Histopathological features</term><term>Igdr</term><term>Interstitial granulomatous drug reaction</term><term>Leishmaniasis</term><term>Likelihood ratio</term><term>Major types</term><term>Malignant</term><term>Medial</term><term>Medial ankle</term><term>Metastatic osteosarcoma</term><term>Mycosis</term><term>Mycosis fungoides</term><term>Nodule</term><term>Osteosarcoma</term><term>Panniculitis</term><term>Rare variant</term><term>Recurrent tumour</term><term>Royal adelaide hospital</term><term>Squamous cell carcinoma</term><term>Tumour</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A case is presented of a 5 year old girl, who over 12 months developed multiple asymptomatic yellow‐brown nodules over the distal digits and nail beds, in association with joint stiffness and swelling. Biopsy of a representative nodule showed a nodular non‐encapsulated dermal histiocytic infiltrate. Within this were scattered multinucleate giant cells with a ground glass eosinophilic cytoplasm consistent with multicentric reticulohistiocytosis (MR). This is a rare subgroup of the non‐Langerhans cell histiocytoses which in contrast to solitary giant cell reticulohistiocytomas, is associated with a destructive arthritis. Typically MR affects Caucasian adults, with paediatric cases being rarely reported. Coeliac antibodies, strongly positive in this case, have only once been described in association with this disease, and may support an autoimmune pathogenesis.</div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Rademaker, M" sort="Rademaker, M" uniqKey="Rademaker M" first="M." last="Rademaker">M. Rademaker</name><name sortKey="Tallon, B" sort="Tallon, B" uniqKey="Tallon B" first="B." last="Tallon">B. Tallon</name><name sortKey="Thorburn, M" sort="Thorburn, M" uniqKey="Thorburn M" first="M." last="Thorburn">M. Thorburn</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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