Serveur d'exploration Chloroquine

Attention, ce site est en cours de développement !
Attention, site généré par des moyens informatiques à partir de corpus bruts.
Les informations ne sont donc pas validées.

[Importance of a regional observatory of malarial chemoresistance, an emerging public health problem in the Guyanas region].

Identifieur interne : 001771 ( Main/Exploration ); précédent : 001770; suivant : 001772

[Importance of a regional observatory of malarial chemoresistance, an emerging public health problem in the Guyanas region].

Auteurs : P. Esterre ; B. Volney ; J.-B. Meynard ; E. Legrand

Source :

RBID : Hal:pasteur-00590980

Descripteurs français

English descriptors

Abstract

A regular implementation of prophylactic and therapeutic decision trees was organized on a consensus basis in Cayenne, French Guiana in 1990, 1995 and 2002. The updated recommendations were based on the knowledge of the in vitro chemosensitivity profiles of the local isolates, mainly coming from big rivers (Maroni and Oyapock, frontiers with Suriname and Brazil, respectively; and more recently Approuague). Most of the patients infected by Plasmodium falciparum were followed by the medical staff of the main hospitals (Cayenne and Saint-Laurent) and of the peripheral health centers in remote areas. Consequently the epidemiological situation and evolution of chemoresistance have been widely observed on a long-term (since 1994) basis in the Maroni region. Yet, we have only partial information coming from the Oyapock valley, even though an important (most of the time) illegal immigration has been developing since the 90s' leading to a notable modification of the epidemiological status of malaria in this eastern region, including a regular increase of P. vivax infections. Presently very little P. vivax chloroquine (and mefloquine) resistance has been identified but this result could lead to a real public health problem in a near future. As such, the National Reference Center on Plasmodium Chemoresistance in the French West Indies and Guiana (CNRCP-AG in French) is a unique observatory of malaria chemoresistance in the Guyanese shield which works with research laboratories of the Institut Pasteur, Paris. This network strategy offers a very attractive perspective for applications of modern tools, including the validation of chemoresistance molecular markers, for malaria control at both medical and public health levels. Some examples related to chloroquine and artemether resistance are given.


Url:


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

<record>
<TEI>
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">[Importance of a regional observatory of malarial chemoresistance, an emerging public health problem in the Guyanas region].</title>
<title xml:lang="fr">Intérêt d'un observatoire régional de la chimiorésistance du paludisme, problème émergent de santé publique dans la région des Guyanes.</title>
<author>
<name sortKey="Esterre, P" sort="Esterre, P" uniqKey="Esterre P" first="P." last="Esterre">P. Esterre</name>
<affiliation>
<hal:affiliation type="institution" xml:id="struct-300193" status="VALID">
<orgName>Institut Pasteur de la Guyane</orgName>
<desc>
<address>
<addrLine>23 Avenue Pasteur BP 6010 - 97306 Cayenne Cedex </addrLine>
<country key="GF"></country>
</address>
<ref type="url">http://www.pasteur-cayenne.fr/</ref>
</desc>
<listRelation>
<relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles>
<tutelle active="#struct-301247" type="direct">
<org type="regroupinstitution" xml:id="struct-301247" status="VALID">
<orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc>
<address>
<addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<wicri:noCountry>GF</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Volney, B" sort="Volney, B" uniqKey="Volney B" first="B." last="Volney">B. Volney</name>
<affiliation>
<hal:affiliation type="institution" xml:id="struct-300193" status="VALID">
<orgName>Institut Pasteur de la Guyane</orgName>
<desc>
<address>
<addrLine>23 Avenue Pasteur BP 6010 - 97306 Cayenne Cedex </addrLine>
<country key="GF"></country>
</address>
<ref type="url">http://www.pasteur-cayenne.fr/</ref>
</desc>
<listRelation>
<relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles>
<tutelle active="#struct-301247" type="direct">
<org type="regroupinstitution" xml:id="struct-301247" status="VALID">
<orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc>
<address>
<addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<wicri:noCountry>GF</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Meynard, J B" sort="Meynard, J B" uniqKey="Meynard J" first="J.-B." last="Meynard">J.-B. Meynard</name>
<affiliation>
<hal:affiliation type="institution" xml:id="struct-300193" status="VALID">
<orgName>Institut Pasteur de la Guyane</orgName>
<desc>
<address>
<addrLine>23 Avenue Pasteur BP 6010 - 97306 Cayenne Cedex </addrLine>
<country key="GF"></country>
</address>
<ref type="url">http://www.pasteur-cayenne.fr/</ref>
</desc>
<listRelation>
<relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles>
<tutelle active="#struct-301247" type="direct">
<org type="regroupinstitution" xml:id="struct-301247" status="VALID">
<orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc>
<address>
<addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<wicri:noCountry>GF</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Legrand, E" sort="Legrand, E" uniqKey="Legrand E" first="E." last="Legrand">E. Legrand</name>
<affiliation>
<hal:affiliation type="institution" xml:id="struct-300193" status="VALID">
<orgName>Institut Pasteur de la Guyane</orgName>
<desc>
<address>
<addrLine>23 Avenue Pasteur BP 6010 - 97306 Cayenne Cedex </addrLine>
<country key="GF"></country>
</address>
<ref type="url">http://www.pasteur-cayenne.fr/</ref>
</desc>
<listRelation>
<relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles>
<tutelle active="#struct-301247" type="direct">
<org type="regroupinstitution" xml:id="struct-301247" status="VALID">
<orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc>
<address>
<addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<wicri:noCountry>GF</wicri:noCountry>
</affiliation>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">HAL</idno>
<idno type="RBID">Hal:pasteur-00590980</idno>
<idno type="halId">pasteur-00590980</idno>
<idno type="halUri">https://hal-riip.archives-ouvertes.fr/pasteur-00590980</idno>
<idno type="url">https://hal-riip.archives-ouvertes.fr/pasteur-00590980</idno>
<date when="2009-08">2009-08</date>
<idno type="wicri:Area/Hal/Corpus">000251</idno>
<idno type="wicri:Area/Hal/Curation">000251</idno>
<idno type="wicri:Area/Hal/Checkpoint">000199</idno>
<idno type="wicri:explorRef" wicri:stream="Hal" wicri:step="Checkpoint">000199</idno>
<idno type="wicri:doubleKey">0037-9085:2009:Esterre P:importance:of:a</idno>
<idno type="wicri:Area/Main/Merge">001775</idno>
<idno type="wicri:Area/Main/Curation">001771</idno>
<idno type="wicri:Area/Main/Exploration">001771</idno>
</publicationStmt>
<sourceDesc>
<biblStruct>
<analytic>
<title xml:lang="en">[Importance of a regional observatory of malarial chemoresistance, an emerging public health problem in the Guyanas region].</title>
<title xml:lang="fr">Intérêt d'un observatoire régional de la chimiorésistance du paludisme, problème émergent de santé publique dans la région des Guyanes.</title>
<author>
<name sortKey="Esterre, P" sort="Esterre, P" uniqKey="Esterre P" first="P." last="Esterre">P. Esterre</name>
<affiliation>
<hal:affiliation type="institution" xml:id="struct-300193" status="VALID">
<orgName>Institut Pasteur de la Guyane</orgName>
<desc>
<address>
<addrLine>23 Avenue Pasteur BP 6010 - 97306 Cayenne Cedex </addrLine>
<country key="GF"></country>
</address>
<ref type="url">http://www.pasteur-cayenne.fr/</ref>
</desc>
<listRelation>
<relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles>
<tutelle active="#struct-301247" type="direct">
<org type="regroupinstitution" xml:id="struct-301247" status="VALID">
<orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc>
<address>
<addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<wicri:noCountry>GF</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Volney, B" sort="Volney, B" uniqKey="Volney B" first="B." last="Volney">B. Volney</name>
<affiliation>
<hal:affiliation type="institution" xml:id="struct-300193" status="VALID">
<orgName>Institut Pasteur de la Guyane</orgName>
<desc>
<address>
<addrLine>23 Avenue Pasteur BP 6010 - 97306 Cayenne Cedex </addrLine>
<country key="GF"></country>
</address>
<ref type="url">http://www.pasteur-cayenne.fr/</ref>
</desc>
<listRelation>
<relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles>
<tutelle active="#struct-301247" type="direct">
<org type="regroupinstitution" xml:id="struct-301247" status="VALID">
<orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc>
<address>
<addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<wicri:noCountry>GF</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Meynard, J B" sort="Meynard, J B" uniqKey="Meynard J" first="J.-B." last="Meynard">J.-B. Meynard</name>
<affiliation>
<hal:affiliation type="institution" xml:id="struct-300193" status="VALID">
<orgName>Institut Pasteur de la Guyane</orgName>
<desc>
<address>
<addrLine>23 Avenue Pasteur BP 6010 - 97306 Cayenne Cedex </addrLine>
<country key="GF"></country>
</address>
<ref type="url">http://www.pasteur-cayenne.fr/</ref>
</desc>
<listRelation>
<relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles>
<tutelle active="#struct-301247" type="direct">
<org type="regroupinstitution" xml:id="struct-301247" status="VALID">
<orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc>
<address>
<addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<wicri:noCountry>GF</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Legrand, E" sort="Legrand, E" uniqKey="Legrand E" first="E." last="Legrand">E. Legrand</name>
<affiliation>
<hal:affiliation type="institution" xml:id="struct-300193" status="VALID">
<orgName>Institut Pasteur de la Guyane</orgName>
<desc>
<address>
<addrLine>23 Avenue Pasteur BP 6010 - 97306 Cayenne Cedex </addrLine>
<country key="GF"></country>
</address>
<ref type="url">http://www.pasteur-cayenne.fr/</ref>
</desc>
<listRelation>
<relation active="#struct-301247" type="direct"></relation>
</listRelation>
<tutelles>
<tutelle active="#struct-301247" type="direct">
<org type="regroupinstitution" xml:id="struct-301247" status="VALID">
<orgName>Réseau International des Instituts Pasteur</orgName>
<orgName type="acronym">RIIP</orgName>
<desc>
<address>
<addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
<country key="FR"></country>
</address>
<ref type="url">https://research.pasteur.fr/ip-network</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<wicri:noCountry>GF</wicri:noCountry>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Bulletin de la Société de pathologie exotique </title>
<idno type="ISSN">0037-9085</idno>
<imprint>
<date type="datePub">2009-08</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="mix" xml:lang="en">
<term>Amérique du Sud</term>
<term>Approuague</term>
<term>Cayenne</term>
<term>Guyana</term>
<term>Guyane française</term>
<term>Maroni</term>
<term>Nord Amazonie</term>
<term>Oyapock</term>
<term>Plasmodium falciparum</term>
<term>Suriname</term>
<term>chimiorésistance</term>
<term>hôpital</term>
<term>tests in vitro</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr">
<term>Guyana</term>
<term>Suriname</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<p>A regular implementation of prophylactic and therapeutic decision trees was organized on a consensus basis in Cayenne, French Guiana in 1990, 1995 and 2002. The updated recommendations were based on the knowledge of the in vitro chemosensitivity profiles of the local isolates, mainly coming from big rivers (Maroni and Oyapock, frontiers with Suriname and Brazil, respectively; and more recently Approuague). Most of the patients infected by Plasmodium falciparum were followed by the medical staff of the main hospitals (Cayenne and Saint-Laurent) and of the peripheral health centers in remote areas. Consequently the epidemiological situation and evolution of chemoresistance have been widely observed on a long-term (since 1994) basis in the Maroni region. Yet, we have only partial information coming from the Oyapock valley, even though an important (most of the time) illegal immigration has been developing since the 90s' leading to a notable modification of the epidemiological status of malaria in this eastern region, including a regular increase of P. vivax infections. Presently very little P. vivax chloroquine (and mefloquine) resistance has been identified but this result could lead to a real public health problem in a near future. As such, the National Reference Center on Plasmodium Chemoresistance in the French West Indies and Guiana (CNRCP-AG in French) is a unique observatory of malaria chemoresistance in the Guyanese shield which works with research laboratories of the Institut Pasteur, Paris. This network strategy offers a very attractive perspective for applications of modern tools, including the validation of chemoresistance molecular markers, for malaria control at both medical and public health levels. Some examples related to chloroquine and artemether resistance are given.</p>
</div>
</front>
</TEI>
<affiliations>
<list></list>
<tree>
<noCountry>
<name sortKey="Esterre, P" sort="Esterre, P" uniqKey="Esterre P" first="P." last="Esterre">P. Esterre</name>
<name sortKey="Legrand, E" sort="Legrand, E" uniqKey="Legrand E" first="E." last="Legrand">E. Legrand</name>
<name sortKey="Meynard, J B" sort="Meynard, J B" uniqKey="Meynard J" first="J.-B." last="Meynard">J.-B. Meynard</name>
<name sortKey="Volney, B" sort="Volney, B" uniqKey="Volney B" first="B." last="Volney">B. Volney</name>
</noCountry>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001771 | SxmlIndent | more

Ou

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001771 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    ChloroquineV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     Hal:pasteur-00590980
   |texte=   [Importance of a regional observatory of malarial chemoresistance, an emerging public health problem in the Guyanas region].
}}

Wicri

This area was generated with Dilib version V0.6.33.
Data generation: Wed Mar 25 22:43:59 2020. Site generation: Sun Jan 31 12:44:45 2021