Overview of Neglected Tropical Diseases
Identifieur interne : 001529 ( Main/Exploration ); précédent : 001528; suivant : 001530Overview of Neglected Tropical Diseases
Auteurs : Federico Gomez De Las Heras [Espagne]Source :
- Topics in Medicinal Chemistry [ 1862-2461 ]
Abstract
Abstract: Neglected tropical diseases (NTDs), caused by a host of pathogens including helminthes, protozoa, bacteria, and viruses, remain a difficult and challenging area for drug discovery, being limited by meager resources and funding, challenged by gaps in knowledge of pathogen biology and drug targets, and faced with limitations specific to the developing world, including stringent cost of good constraints, the lack of robust infrastructure to effectively deliver and administer drug therapy, and socioeconomic considerations in disease endemic areas. This chapter will endeavor to provide a general overview of scientific approaches for NTDs, and review some of the current challenges and advancements in diseases of the developing world (DDW) drug discovery, as well as discuss the interplay between international networks of organizations, foundations, and public and private partners involved in neglected disease drug discovery. This chapter will also review general aspects and considerations common to many or all of these diseases, including burden of disease, coinfections, pathogenicity, drug resistance, drug combination therapy, and mass drug administration programs. This chapter will briefly address disease treatment on a general level, including the treatment of coinfections and care of special groups of patients, such as children and pregnant women.
Url:
DOI: 10.1007/7355_2011_12
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001150
- to stream Istex, to step Curation: 001150
- to stream Istex, to step Checkpoint: 000505
- to stream Main, to step Merge: 001531
- to stream Main, to step Curation: 001529
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Overview of Neglected Tropical Diseases</title><author><name sortKey="De Las Heras, Federico Gomez" sort="De Las Heras, Federico Gomez" uniqKey="De Las Heras F" first="Federico Gomez" last="De Las Heras">Federico Gomez De Las Heras</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:AA9E679AE13B824703B1C2CD79AE02A3A4F1D8E3</idno><date when="2011" year="2011">2011</date><idno type="doi">10.1007/7355_2011_12</idno><idno type="url">https://api.istex.fr/ark:/67375/HCB-9CMD7HP1-5/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">001150</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001150</idno><idno type="wicri:Area/Istex/Curation">001150</idno><idno type="wicri:Area/Istex/Checkpoint">000505</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000505</idno><idno type="wicri:doubleKey">1862-2461:2011:De Las Heras F:overview:of:neglected</idno><idno type="wicri:Area/Main/Merge">001531</idno><idno type="wicri:Area/Main/Curation">001529</idno><idno type="wicri:Area/Main/Exploration">001529</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Overview of Neglected Tropical Diseases</title><author><name sortKey="De Las Heras, Federico Gomez" sort="De Las Heras, Federico Gomez" uniqKey="De Las Heras F" first="Federico Gomez" last="De Las Heras">Federico Gomez De Las Heras</name><affiliation wicri:level="3"><country xml:lang="fr">Espagne</country><wicri:regionArea>Paseo de los Cerezos 5, 28016, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Espagne</country></affiliation></author></analytic><monogr></monogr><series><title level="s" type="main" xml:lang="en">Topics in Medicinal Chemistry</title><title level="s" type="abbrev">Topics Medicinal Chemistry</title><idno type="ISSN">1862-2461</idno><idno type="eISSN">1862-247X</idno><idno type="ISSN">1862-2461</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1862-2461</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Neglected tropical diseases (NTDs), caused by a host of pathogens including helminthes, protozoa, bacteria, and viruses, remain a difficult and challenging area for drug discovery, being limited by meager resources and funding, challenged by gaps in knowledge of pathogen biology and drug targets, and faced with limitations specific to the developing world, including stringent cost of good constraints, the lack of robust infrastructure to effectively deliver and administer drug therapy, and socioeconomic considerations in disease endemic areas. This chapter will endeavor to provide a general overview of scientific approaches for NTDs, and review some of the current challenges and advancements in diseases of the developing world (DDW) drug discovery, as well as discuss the interplay between international networks of organizations, foundations, and public and private partners involved in neglected disease drug discovery. This chapter will also review general aspects and considerations common to many or all of these diseases, including burden of disease, coinfections, pathogenicity, drug resistance, drug combination therapy, and mass drug administration programs. This chapter will briefly address disease treatment on a general level, including the treatment of coinfections and care of special groups of patients, such as children and pregnant women.</div></front></TEI><affiliations><list><country><li>Espagne</li></country><region><li>Communauté de Madrid</li></region><settlement><li>Madrid</li></settlement></list><tree><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="De Las Heras, Federico Gomez" sort="De Las Heras, Federico Gomez" uniqKey="De Las Heras F" first="Federico Gomez" last="De Las Heras">Federico Gomez De Las Heras</name></region><name sortKey="De Las Heras, Federico Gomez" sort="De Las Heras, Federico Gomez" uniqKey="De Las Heras F" first="Federico Gomez" last="De Las Heras">Federico Gomez De Las Heras</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001529 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001529 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= ChloroquineV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:AA9E679AE13B824703B1C2CD79AE02A3A4F1D8E3
|texte= Overview of Neglected Tropical Diseases
}}
| This area was generated with Dilib version V0.6.33. |  |