Ventricular assist device support as a bridge to heart transplantation in patients with giant cell myocarditis
Identifieur interne : 001319 ( Main/Exploration ); précédent : 001318; suivant : 001320Ventricular assist device support as a bridge to heart transplantation in patients with giant cell myocarditis
Auteurs : Lindsay K. Murray [États-Unis] ; Jose González-Costello [États-Unis] ; Samual N. Jonas [États-Unis] ; Daniel B. Sims [États-Unis] ; Kerry A. Morrison [États-Unis] ; Paolo C. Colombo [États-Unis] ; Donna M. Mancini [États-Unis] ; Susan W. Restaino [États-Unis] ; Evan Joye [États-Unis] ; Evelyn Horn [États-Unis] ; Hiroo Takayama [États-Unis] ; Charles C. Marboe [États-Unis] ; Yoshifumi Naka [États-Unis] ; Ulrich P. Jorde [États-Unis] ; Nir Uriel [États-Unis]Source :
- European Journal of Heart Failure [ 1388-9842 ] ; 2012-03.
Abstract
Aims: Giant cell myocarditis (GCM) carries a poor prognosis and many patients require end‐stage therapies. This study sought to determine the outcome of patients bridged with ventricular assist devices (VAD) to orthotopic heart transplantation (OHT). Methods and results: A retrospective data collection of all patients with GCM was performed. Diagnosis was determined by endomyocardial or explanted heart biopsy. Eight patients were found, but two of those patients went directly to OHT and were excluded. The remaining six patients received VADs, and these patients, aged 44 ± 18 years, were included. Five of the six patients were bridged with biventricular support and one patient was supported by left ventricular assist device (LVAD) alone. Two patients died on device support. Four patients were bridged to OHT 77 ± 42 days after device implantation. All four patients bridged with a VAD are alive, with a mean follow‐up of 5.7 ± 4.1 years. Two patients were found to have recurrent GCM in the transplanted heart and were treated successfully with immunosuppression. Three patients had high grade (2R) rejection at 66 ± 52 days post‐OHT. Cardiac function was preserved in all patients, and only one patient had cardiac allograft vasculopathy. Conclusion: Patients with end‐stage GCM can be successfully bridged with VADs to OHT with very good post‐OHT survival. The proper immunosuppressive regimen for this group needs further investigation given the frequency of rejection and GCM recurrence.
Url:
DOI: 10.1093/eurjhf/hfr174
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000664
- to stream Istex, to step Curation: 000664
- to stream Istex, to step Checkpoint: 000328
- to stream Main, to step Merge: 001320
- to stream Main, to step Curation: 001319
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Ventricular assist device support as a bridge to heart transplantation in patients with giant cell myocarditis</title><author><name sortKey="Murray, Lindsay K" sort="Murray, Lindsay K" uniqKey="Murray L" first="Lindsay K." last="Murray">Lindsay K. Murray</name></author><author><name sortKey="Gonzalez Ostello, Jose" sort="Gonzalez Ostello, Jose" uniqKey="Gonzalez Ostello J" first="Jose" last="González-Costello">Jose González-Costello</name></author><author><name sortKey="Jonas, Samual N" sort="Jonas, Samual N" uniqKey="Jonas S" first="Samual N." last="Jonas">Samual N. Jonas</name></author><author><name sortKey="Sims, Daniel B" sort="Sims, Daniel B" uniqKey="Sims D" first="Daniel B." last="Sims">Daniel B. Sims</name></author><author><name sortKey="Morrison, Kerry A" sort="Morrison, Kerry A" uniqKey="Morrison K" first="Kerry A." last="Morrison">Kerry A. Morrison</name></author><author><name sortKey="Colombo, Paolo C" sort="Colombo, Paolo C" uniqKey="Colombo P" first="Paolo C." last="Colombo">Paolo C. Colombo</name></author><author><name sortKey="Mancini, Donna M" sort="Mancini, Donna M" uniqKey="Mancini D" first="Donna M." last="Mancini">Donna M. Mancini</name></author><author><name sortKey="Restaino, Susan W" sort="Restaino, Susan W" uniqKey="Restaino S" first="Susan W." last="Restaino">Susan W. Restaino</name></author><author><name sortKey="Joye, Evan" sort="Joye, Evan" uniqKey="Joye E" first="Evan" last="Joye">Evan Joye</name></author><author><name sortKey="Horn, Evelyn" sort="Horn, Evelyn" uniqKey="Horn E" first="Evelyn" last="Horn">Evelyn Horn</name></author><author><name sortKey="Takayama, Hiroo" sort="Takayama, Hiroo" uniqKey="Takayama H" first="Hiroo" last="Takayama">Hiroo Takayama</name></author><author><name sortKey="Marboe, Charles C" sort="Marboe, Charles C" uniqKey="Marboe C" first="Charles C." last="Marboe">Charles C. Marboe</name></author><author><name sortKey="Naka, Yoshifumi" sort="Naka, Yoshifumi" uniqKey="Naka Y" first="Yoshifumi" last="Naka">Yoshifumi Naka</name></author><author><name sortKey="Jorde, Ulrich P" sort="Jorde, Ulrich P" uniqKey="Jorde U" first="Ulrich P." last="Jorde">Ulrich P. Jorde</name></author><author><name sortKey="Uriel, Nir" sort="Uriel, Nir" uniqKey="Uriel N" first="Nir" last="Uriel">Nir Uriel</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:6112039D4D9335288F2B69865CF34C068DD538A8</idno><date when="2012" year="2012">2012</date><idno type="doi">10.1093/eurjhf/hfr174</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-4ZQ3DJGK-D/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000664</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000664</idno><idno type="wicri:Area/Istex/Curation">000664</idno><idno type="wicri:Area/Istex/Checkpoint">000328</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000328</idno><idno type="wicri:doubleKey">1388-9842:2012:Murray L:ventricular:assist:device</idno><idno type="wicri:Area/Main/Merge">001320</idno><idno type="wicri:Area/Main/Curation">001319</idno><idno type="wicri:Area/Main/Exploration">001319</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Ventricular assist device support as a bridge to heart transplantation in patients with giant cell myocarditis</title><author><name sortKey="Murray, Lindsay K" sort="Murray, Lindsay K" uniqKey="Murray L" first="Lindsay K." last="Murray">Lindsay K. Murray</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medicine, Columbia University, NY10032, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Gonzalez Ostello, Jose" sort="Gonzalez Ostello, Jose" uniqKey="Gonzalez Ostello J" first="Jose" last="González-Costello">Jose González-Costello</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medicine, Columbia University, NY10032, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Jonas, Samual N" sort="Jonas, Samual N" uniqKey="Jonas S" first="Samual N." last="Jonas">Samual N. Jonas</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medicine, Columbia University, NY10032, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Sims, Daniel B" sort="Sims, Daniel B" uniqKey="Sims D" first="Daniel B." last="Sims">Daniel B. Sims</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medicine, Columbia University, NY10032, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Morrison, Kerry A" sort="Morrison, Kerry A" uniqKey="Morrison K" first="Kerry A." last="Morrison">Kerry A. Morrison</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medicine, Columbia University, NY10032, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Colombo, Paolo C" sort="Colombo, Paolo C" uniqKey="Colombo P" first="Paolo C." last="Colombo">Paolo C. Colombo</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medicine, Columbia University, NY10032, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Mancini, Donna M" sort="Mancini, Donna M" uniqKey="Mancini D" first="Donna M." last="Mancini">Donna M. Mancini</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medicine, Columbia University, NY10032, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Restaino, Susan W" sort="Restaino, Susan W" uniqKey="Restaino S" first="Susan W." last="Restaino">Susan W. Restaino</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medicine, Columbia University, NY10032, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Joye, Evan" sort="Joye, Evan" uniqKey="Joye E" first="Evan" last="Joye">Evan Joye</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medicine, Columbia University, NY10032, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Horn, Evelyn" sort="Horn, Evelyn" uniqKey="Horn E" first="Evelyn" last="Horn">Evelyn Horn</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medicine, Columbia University, NY10032, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Takayama, Hiroo" sort="Takayama, Hiroo" uniqKey="Takayama H" first="Hiroo" last="Takayama">Hiroo Takayama</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Surgery, Columbia University, NY, 10032, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Marboe, Charles C" sort="Marboe, Charles C" uniqKey="Marboe C" first="Charles C." last="Marboe">Charles C. Marboe</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology and Cell Biology, Columbia University, NY, 10032, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Naka, Yoshifumi" sort="Naka, Yoshifumi" uniqKey="Naka Y" first="Yoshifumi" last="Naka">Yoshifumi Naka</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Surgery, Columbia University, NY, 10032, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Jorde, Ulrich P" sort="Jorde, Ulrich P" uniqKey="Jorde U" first="Ulrich P." last="Jorde">Ulrich P. Jorde</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medicine, Columbia University, NY10032, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Uriel, Nir" sort="Uriel, Nir" uniqKey="Uriel N" first="Nir" last="Uriel">Nir Uriel</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medicine, Columbia University, NY10032, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation><affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">European Journal of Heart Failure</title><title level="j" type="alt">EUROPEAN JOURNAL OF HEART FAILURE</title><idno type="ISSN">1388-9842</idno><idno type="eISSN">1879-0844</idno><imprint><biblScope unit="vol">14</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="312">312</biblScope><biblScope unit="page" to="318">318</biblScope><biblScope unit="page-count">7</biblScope><date type="published" when="2012-03">2012-03</date></imprint><idno type="ISSN">1388-9842</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1388-9842</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract">Aims: Giant cell myocarditis (GCM) carries a poor prognosis and many patients require end‐stage therapies. This study sought to determine the outcome of patients bridged with ventricular assist devices (VAD) to orthotopic heart transplantation (OHT). Methods and results: A retrospective data collection of all patients with GCM was performed. Diagnosis was determined by endomyocardial or explanted heart biopsy. Eight patients were found, but two of those patients went directly to OHT and were excluded. The remaining six patients received VADs, and these patients, aged 44 ± 18 years, were included. Five of the six patients were bridged with biventricular support and one patient was supported by left ventricular assist device (LVAD) alone. Two patients died on device support. Four patients were bridged to OHT 77 ± 42 days after device implantation. All four patients bridged with a VAD are alive, with a mean follow‐up of 5.7 ± 4.1 years. Two patients were found to have recurrent GCM in the transplanted heart and were treated successfully with immunosuppression. Three patients had high grade (2R) rejection at 66 ± 52 days post‐OHT. Cardiac function was preserved in all patients, and only one patient had cardiac allograft vasculopathy. Conclusion: Patients with end‐stage GCM can be successfully bridged with VADs to OHT with very good post‐OHT survival. The proper immunosuppressive regimen for this group needs further investigation given the frequency of rejection and GCM recurrence.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>État de New York</li></region><settlement><li>New York</li></settlement><orgName><li>Université Columbia</li></orgName></list><tree><country name="États-Unis"><region name="État de New York"><name sortKey="Murray, Lindsay K" sort="Murray, Lindsay K" uniqKey="Murray L" first="Lindsay K." last="Murray">Lindsay K. Murray</name></region><name sortKey="Colombo, Paolo C" sort="Colombo, Paolo C" uniqKey="Colombo P" first="Paolo C." last="Colombo">Paolo C. Colombo</name><name sortKey="Gonzalez Ostello, Jose" sort="Gonzalez Ostello, Jose" uniqKey="Gonzalez Ostello J" first="Jose" last="González-Costello">Jose González-Costello</name><name sortKey="Horn, Evelyn" sort="Horn, Evelyn" uniqKey="Horn E" first="Evelyn" last="Horn">Evelyn Horn</name><name sortKey="Jonas, Samual N" sort="Jonas, Samual N" uniqKey="Jonas S" first="Samual N." last="Jonas">Samual N. Jonas</name><name sortKey="Jorde, Ulrich P" sort="Jorde, Ulrich P" uniqKey="Jorde U" first="Ulrich P." last="Jorde">Ulrich P. Jorde</name><name sortKey="Joye, Evan" sort="Joye, Evan" uniqKey="Joye E" first="Evan" last="Joye">Evan Joye</name><name sortKey="Mancini, Donna M" sort="Mancini, Donna M" uniqKey="Mancini D" first="Donna M." last="Mancini">Donna M. Mancini</name><name sortKey="Marboe, Charles C" sort="Marboe, Charles C" uniqKey="Marboe C" first="Charles C." last="Marboe">Charles C. Marboe</name><name sortKey="Morrison, Kerry A" sort="Morrison, Kerry A" uniqKey="Morrison K" first="Kerry A." last="Morrison">Kerry A. Morrison</name><name sortKey="Naka, Yoshifumi" sort="Naka, Yoshifumi" uniqKey="Naka Y" first="Yoshifumi" last="Naka">Yoshifumi Naka</name><name sortKey="Restaino, Susan W" sort="Restaino, Susan W" uniqKey="Restaino S" first="Susan W." last="Restaino">Susan W. Restaino</name><name sortKey="Sims, Daniel B" sort="Sims, Daniel B" uniqKey="Sims D" first="Daniel B." last="Sims">Daniel B. Sims</name><name sortKey="Takayama, Hiroo" sort="Takayama, Hiroo" uniqKey="Takayama H" first="Hiroo" last="Takayama">Hiroo Takayama</name><name sortKey="Uriel, Nir" sort="Uriel, Nir" uniqKey="Uriel N" first="Nir" last="Uriel">Nir Uriel</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001319 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001319 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= ChloroquineV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:6112039D4D9335288F2B69865CF34C068DD538A8
|texte= Ventricular assist device support as a bridge to heart transplantation in patients with giant cell myocarditis
}}
| This area was generated with Dilib version V0.6.33. |  |