ChloroquineV1, Main, Exploration, bibRecord, 000C33

High Tidal Volume Induces Mitochondria Damage and Releases Mitochondrial DNA to Aggravate the Ventilator-Induced Lung Injury.

Identifieur interne : 000C33 ( Main/Exploration ); précédent : 000C32; suivant : 000C34

High Tidal Volume Induces Mitochondria Damage and Releases Mitochondrial DNA to Aggravate the Ventilator-Induced Lung Injury.

Auteurs : Jin-Yuan Lin [République populaire de Chine] ; Ren Jing [République populaire de Chine] ; Fei Lin [République populaire de Chine] ; Wan-Yun Ge [République populaire de Chine] ; Hui-Jun Dai [République populaire de Chine] ; Linghui Pan [République populaire de Chine]

Source :

Frontiers in immunology [ 1664-3224 ] ; 2018.

RBID : pubmed:30018615

Abstract

This study aimed to determine whether high tidal volume (HTV) induce mitochondria damage and mitophagy, contributing to the release of mitochondrial DNA (mtDNA). Another aim of the present study was to investigate the role and mechanism of mtDNA in ventilator-induced lung injury (VILI) in rats.

DOI: 10.3389/fimmu.2018.01477
PubMed: 30018615

Affiliations:

République populaire de Chine

Le document en format XML

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<front><div type="abstract" xml:lang="en">This study aimed to determine whether high tidal volume (HTV) induce mitochondria damage and mitophagy, contributing to the release of mitochondrial DNA (mtDNA). Another aim of the present study was to investigate the role and mechanism of mtDNA in ventilator-induced lung injury (VILI) in rats.</div>
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High Tidal Volume Induces Mitochondria Damage and Releases Mitochondrial DNA to Aggravate the Ventilator-Induced Lung Injury.

High Tidal Volume Induces Mitochondria Damage and Releases Mitochondrial DNA to Aggravate the Ventilator-Induced Lung Injury.

Source :

Abstract

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