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Maytenus macrocarpa (Ruiz & Pav.) Briq.: Phytochemistry and Pharmacological Activity

Identifieur interne : 000B61 ( Main/Exploration ); précédent : 000B60; suivant : 000B62

Maytenus macrocarpa (Ruiz & Pav.) Briq.: Phytochemistry and Pharmacological Activity

Auteurs : Milan Malaník ; Jakub Treml ; Veronika Rjašková ; Karolina Tížková ; Petra Kaucká ; Ladislav Kokoška ; Peter Kubatka ; Karel Šmejkal

Source :

RBID : PMC:6630539

Abstract

Maytenus macrocarpa (Celastraceae) is a tree native to Amazonia. Its roots, leaves, bark, and combinations of these are used in traditional medicine mainly to treat rheumatism and, to a lesser extent, to heal wounds and to combat bronchitis and diarrhea. To date, mainly triterpenes and dihydro-β-agarofuran sesquiterpenes were isolated from M. macrocarpa. Extracts and selected pure compounds isolated from the leaves, roots, and stem bark showed antibacterial, antiviral, antiparasitic, anti-inflammatory, and cytotoxic activities in vitro. The aim of this review is to summarize the available ethnobotanical, phytochemical, and pharmacological information about this traditional Amazonian medicinal tree, as well as to attract the attention of phytochemists and pharmacognosists to this potentially interesting source of ethnopharmaceuticals.


Url:
DOI: 10.3390/molecules24122288
PubMed: 31226757
PubMed Central: 6630539


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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<nlm:aff id="af1-molecules-24-02288">Department of Natural Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Palackého tř. 1, 61242 Brno, Czech Republic;
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<div type="abstract" xml:lang="en">
<p>
<italic>Maytenus macrocarpa</italic>
(Celastraceae) is a tree native to Amazonia. Its roots, leaves, bark, and combinations of these are used in traditional medicine mainly to treat rheumatism and, to a lesser extent, to heal wounds and to combat bronchitis and diarrhea. To date, mainly triterpenes and dihydro-β-agarofuran sesquiterpenes were isolated from
<italic>M. macrocarpa</italic>
. Extracts and selected pure compounds isolated from the leaves, roots, and stem bark showed antibacterial, antiviral, antiparasitic, anti-inflammatory, and cytotoxic activities in vitro. The aim of this review is to summarize the available ethnobotanical, phytochemical, and pharmacological information about this traditional Amazonian medicinal tree, as well as to attract the attention of phytochemists and pharmacognosists to this potentially interesting source of ethnopharmaceuticals.</p>
</div>
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</author>
<author>
<name sortKey="Zhao, P" uniqKey="Zhao P">P. Zhao</name>
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</analytic>
</biblStruct>
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<analytic>
<author>
<name sortKey="Morikawa, T" uniqKey="Morikawa T">T. Morikawa</name>
</author>
<author>
<name sortKey="Kishi, A" uniqKey="Kishi A">A. Kishi</name>
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<author>
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</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
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</author>
<author>
<name sortKey="Shimoda, H" uniqKey="Shimoda H">H. Shimoda</name>
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<biblStruct>
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</biblStruct>
<biblStruct>
<analytic>
<author>
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</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<affiliations>
<list></list>
<tree>
<noCountry>
<name sortKey="Kaucka, Petra" sort="Kaucka, Petra" uniqKey="Kaucka P" first="Petra" last="Kaucká">Petra Kaucká</name>
<name sortKey="Kokoska, Ladislav" sort="Kokoska, Ladislav" uniqKey="Kokoska L" first="Ladislav" last="Kokoška">Ladislav Kokoška</name>
<name sortKey="Kubatka, Peter" sort="Kubatka, Peter" uniqKey="Kubatka P" first="Peter" last="Kubatka">Peter Kubatka</name>
<name sortKey="Malanik, Milan" sort="Malanik, Milan" uniqKey="Malanik M" first="Milan" last="Malaník">Milan Malaník</name>
<name sortKey="Rjaskova, Veronika" sort="Rjaskova, Veronika" uniqKey="Rjaskova V" first="Veronika" last="Rjašková">Veronika Rjašková</name>
<name sortKey="Smejkal, Karel" sort="Smejkal, Karel" uniqKey="Smejkal K" first="Karel" last="Šmejkal">Karel Šmejkal</name>
<name sortKey="Tizkova, Karolina" sort="Tizkova, Karolina" uniqKey="Tizkova K" first="Karolina" last="Tížková">Karolina Tížková</name>
<name sortKey="Treml, Jakub" sort="Treml, Jakub" uniqKey="Treml J" first="Jakub" last="Treml">Jakub Treml</name>
</noCountry>
</tree>
</affiliations>
</record>

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