ChloroquineV1, Main, Exploration, bibRecord, 000872

Drug-induced liver injury

Identifieur interne : 000872 ( Main/Exploration ); précédent : 000871; suivant : 000873

Drug-induced liver injury

Source :

Yeungnam University Journal of Medicine [ 2384-0293 ] ; 2019.

RBID : PMC:6986960

Abstract

Drug-induced liver injury (DILI), including herbal and dietary supplement hepatotoxicity, is often passed lightly; however, it can lead to the requirement of a liver transplant or may even cause death because of liver failure. Recently, the American College of Gastroenterology, Chinese Society of Hepatology and European Association for the Study of the Liver guidelines for the diagnosis and treatment of DILI have been established, and they will be helpful for guiding clinical treatment decisions. Roussel Uclaf Causality Assessment Method scoring is the most commonly used method to diagnose DILI; however, it has some limitations, such as poor validity and reproducibility. Recently, studies on new biomarkers have been actively carried out, which will help diagnose DILI and predict the prognosis of DILI. It is expected that the development of new therapies such as autophagy inducers and various other technologies of the fourth industrial revolution will be applicable to DILI research.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986960

DOI: 10.12701/yujm.2019.00297
PubMed: 31661757
PubMed Central: 6986960

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en"><p>Drug-induced liver injury (DILI), including herbal and dietary supplement hepatotoxicity, is often passed lightly; however, it can lead to the requirement of a liver transplant or may even cause death because of liver failure. Recently, the American College of Gastroenterology, Chinese Society of Hepatology and European Association for the Study of the Liver guidelines for the diagnosis and treatment of DILI have been established, and they will be helpful for guiding clinical treatment decisions. Roussel Uclaf Causality Assessment Method scoring is the most commonly used method to diagnose DILI; however, it has some limitations, such as poor validity and reproducibility. Recently, studies on new biomarkers have been actively carried out, which will help diagnose DILI and predict the prognosis of DILI. It is expected that the development of new therapies such as autophagy inducers and various other technologies of the fourth industrial revolution will be applicable to DILI research.</p>
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   |area=    ChloroquineV1
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   |texte=   Drug-induced liver injury
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Serveur d'exploration Chloroquine

Drug-induced liver injury

Drug-induced liver injury

Source :

Abstract

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	Serveur d'exploration Chloroquine
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