Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3
Identifieur interne : 000754 ( Main/Exploration ); précédent : 000753; suivant : 000755Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3
Auteurs : Matthias Von Gamm ; Annalisa Schaub ; Alisha N. Jones ; Christine Wolf ; Gesine Behrens ; Johannes Lichti ; Katharina Essig ; Anna Macht ; Joachim Pircher ; Andreas Ehrlich ; Kathrin Davari ; Dhruv Chauhan ; Benjamin Busch ; Wolfgang Wurst ; Regina Feederle ; Annette Feuchtinger ; Matthias H. Tschöp ; Caroline C. Friedel ; Stefanie M. Hauck ; Michael Sattler ; Arie Geerlof ; Veit Hornung ; Vigo Heissmeyer ; Christian Schulz ; Mathias Heikenwalder ; Elke GlasmacherSource :
- The Journal of Experimental Medicine [ 0022-1007 ] ; 2019.
Abstract
von Gamm et al. demonstrate that mice deficient for the RNase Regnase-3 (Zc3h12c) develop hypertrophic lymph nodes and a systemic interferon response. Regnase-3 is a functional RNase that acts in myeloid cells upon IRF signaling, suggesting it to be an evolutionary counterpart to Regnase-1.
Url:
DOI: 10.1084/jem.20181762
PubMed: 31126966
PubMed Central: 6605757
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000672
- to stream Pmc, to step Curation: 000672
- to stream Pmc, to step Checkpoint: 000698
- to stream Ncbi, to step Merge: 000649
- to stream Ncbi, to step Curation: 000649
- to stream Ncbi, to step Checkpoint: 000649
- to stream Main, to step Merge: 000754
- to stream Main, to step Curation: 000754
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3</title><author><name sortKey="Von Gamm, Matthias" sort="Von Gamm, Matthias" uniqKey="Von Gamm M" first="Matthias" last="Von Gamm">Matthias Von Gamm</name><affiliation><nlm:aff id="aff1"><institution>Institute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Schaub, Annalisa" sort="Schaub, Annalisa" uniqKey="Schaub A" first="Annalisa" last="Schaub">Annalisa Schaub</name><affiliation><nlm:aff id="aff1"><institution>Institute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation><affiliation><nlm:aff id="aff2"><institution>Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Jones, Alisha N" sort="Jones, Alisha N" uniqKey="Jones A" first="Alisha N." last="Jones">Alisha N. Jones</name><affiliation><nlm:aff id="aff3"><institution>Institute of Structural Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation><affiliation><nlm:aff id="aff4"><institution>Center for Integrated Protein Science Munich, Chemistry Department, Technical University of Munich, Garching, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Wolf, Christine" sort="Wolf, Christine" uniqKey="Wolf C" first="Christine" last="Wolf">Christine Wolf</name><affiliation><nlm:aff id="aff5"><institution>Institute of Environmental Medicine, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Behrens, Gesine" sort="Behrens, Gesine" uniqKey="Behrens G" first="Gesine" last="Behrens">Gesine Behrens</name><affiliation><nlm:aff id="aff6"><institution>Institute for Immunology, Biomedical Center, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Lichti, Johannes" sort="Lichti, Johannes" uniqKey="Lichti J" first="Johannes" last="Lichti">Johannes Lichti</name><affiliation><nlm:aff id="aff1"><institution>Institute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Essig, Katharina" sort="Essig, Katharina" uniqKey="Essig K" first="Katharina" last="Essig">Katharina Essig</name><affiliation><nlm:aff id="aff7"><institution>Roche Pharma Research and Early Development, Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Macht, Anna" sort="Macht, Anna" uniqKey="Macht A" first="Anna" last="Macht">Anna Macht</name><affiliation><nlm:aff id="aff1"><institution>Institute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Pircher, Joachim" sort="Pircher, Joachim" uniqKey="Pircher J" first="Joachim" last="Pircher">Joachim Pircher</name><affiliation><nlm:aff id="aff8"><institution>Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Ludwig-Maximilians-University, Munich, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Ehrlich, Andreas" sort="Ehrlich, Andreas" uniqKey="Ehrlich A" first="Andreas" last="Ehrlich">Andreas Ehrlich</name><affiliation><nlm:aff id="aff8"><institution>Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Ludwig-Maximilians-University, Munich, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Davari, Kathrin" sort="Davari, Kathrin" uniqKey="Davari K" first="Kathrin" last="Davari">Kathrin Davari</name><affiliation><nlm:aff id="aff9"><institution>Medigene Immunotherapies, Planegg-Martinsried, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Chauhan, Dhruv" sort="Chauhan, Dhruv" uniqKey="Chauhan D" first="Dhruv" last="Chauhan">Dhruv Chauhan</name><affiliation><nlm:aff id="aff10"><institution>Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Busch, Benjamin" sort="Busch, Benjamin" uniqKey="Busch B" first="Benjamin" last="Busch">Benjamin Busch</name><affiliation><nlm:aff id="aff11"><institution>Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, Ludwig-Maximilians-Universität München, Munich, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Wurst, Wolfgang" sort="Wurst, Wolfgang" uniqKey="Wurst W" first="Wolfgang" last="Wurst">Wolfgang Wurst</name><affiliation><nlm:aff id="aff12"><institution>Institute of Developmental Genetics, Helmholtz Zentrum München, Munich, Germany</institution></nlm:aff></affiliation><affiliation><nlm:aff id="aff13"><institution>Technische Universität München-Weihenstephan, Neuherberg-Munich, Germany</institution></nlm:aff></affiliation><affiliation><nlm:aff id="aff14"><institution>German Center for Neurodegenerative Diseases, Munich, Germany</institution></nlm:aff></affiliation><affiliation><nlm:aff id="aff15"><institution>Munich Cluster for Systems Neurology, Munich, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Feederle, Regina" sort="Feederle, Regina" uniqKey="Feederle R" first="Regina" last="Feederle">Regina Feederle</name><affiliation><nlm:aff id="aff16"><institution>Monoclonal Antibody Core Facility, Institute for Diabetes and Obesity, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Feuchtinger, Annette" sort="Feuchtinger, Annette" uniqKey="Feuchtinger A" first="Annette" last="Feuchtinger">Annette Feuchtinger</name><affiliation><nlm:aff id="aff17"><institution>Research Unit Analytical Pathology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Tschop, Matthias H" sort="Tschop, Matthias H" uniqKey="Tschop M" first="Matthias H." last="Tschöp">Matthias H. Tschöp</name><affiliation><nlm:aff id="aff1"><institution>Institute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation><affiliation><nlm:aff id="aff18"><institution>Division of Metabolic Diseases, Department of Medicine, Technische Universität München, Munich, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Friedel, Caroline C" sort="Friedel, Caroline C" uniqKey="Friedel C" first="Caroline C." last="Friedel">Caroline C. Friedel</name><affiliation><nlm:aff id="aff19"><institution>Institute for Informatics, Ludwig-Maximilians-Universität München, Munich, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Hauck, Stefanie M" sort="Hauck, Stefanie M" uniqKey="Hauck S" first="Stefanie M." last="Hauck">Stefanie M. Hauck</name><affiliation><nlm:aff id="aff20"><institution>Research Unit Protein Science, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Sattler, Michael" sort="Sattler, Michael" uniqKey="Sattler M" first="Michael" last="Sattler">Michael Sattler</name><affiliation><nlm:aff id="aff3"><institution>Institute of Structural Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation><affiliation><nlm:aff id="aff4"><institution>Center for Integrated Protein Science Munich, Chemistry Department, Technical University of Munich, Garching, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Geerlof, Arie" sort="Geerlof, Arie" uniqKey="Geerlof A" first="Arie" last="Geerlof">Arie Geerlof</name><affiliation><nlm:aff id="aff3"><institution>Institute of Structural Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Hornung, Veit" sort="Hornung, Veit" uniqKey="Hornung V" first="Veit" last="Hornung">Veit Hornung</name><affiliation><nlm:aff id="aff10"><institution>Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Heissmeyer, Vigo" sort="Heissmeyer, Vigo" uniqKey="Heissmeyer V" first="Vigo" last="Heissmeyer">Vigo Heissmeyer</name><affiliation><nlm:aff id="aff6"><institution>Institute for Immunology, Biomedical Center, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany</institution></nlm:aff></affiliation><affiliation><nlm:aff id="aff21"><institution>Research Unit Molecular Immune Regulation, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Schulz, Christian" sort="Schulz, Christian" uniqKey="Schulz C" first="Christian" last="Schulz">Christian Schulz</name><affiliation><nlm:aff id="aff8"><institution>Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Ludwig-Maximilians-University, Munich, Germany</institution></nlm:aff></affiliation><affiliation><nlm:aff id="aff22"><institution>German Center for Cardiovascular Research, partner site Munich Heart Alliance, Munich, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Heikenwalder, Mathias" sort="Heikenwalder, Mathias" uniqKey="Heikenwalder M" first="Mathias" last="Heikenwalder">Mathias Heikenwalder</name><affiliation><nlm:aff id="aff23"><institution>Division of Chronic Inflammation and Cancer (F180), German Cancer Research Center, Heidelberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Glasmacher, Elke" sort="Glasmacher, Elke" uniqKey="Glasmacher E" first="Elke" last="Glasmacher">Elke Glasmacher</name><affiliation><nlm:aff id="aff1"><institution>Institute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation><affiliation><nlm:aff id="aff7"><institution>Roche Pharma Research and Early Development, Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germany</institution></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">31126966</idno><idno type="pmc">6605757</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605757</idno><idno type="RBID">PMC:6605757</idno><idno type="doi">10.1084/jem.20181762</idno><date when="2019">2019</date><idno type="wicri:Area/Pmc/Corpus">000672</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000672</idno><idno type="wicri:Area/Pmc/Curation">000672</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000672</idno><idno type="wicri:Area/Pmc/Checkpoint">000698</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000698</idno><idno type="wicri:Area/Ncbi/Merge">000649</idno><idno type="wicri:Area/Ncbi/Curation">000649</idno><idno type="wicri:Area/Ncbi/Checkpoint">000649</idno><idno type="wicri:doubleKey">0022-1007:2019:Von Gamm M:immune:homeostasis:and</idno><idno type="wicri:Area/Main/Merge">000754</idno><idno type="wicri:Area/Main/Curation">000754</idno><idno type="wicri:Area/Main/Exploration">000754</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3</title><author><name sortKey="Von Gamm, Matthias" sort="Von Gamm, Matthias" uniqKey="Von Gamm M" first="Matthias" last="Von Gamm">Matthias Von Gamm</name><affiliation><nlm:aff id="aff1"><institution>Institute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Schaub, Annalisa" sort="Schaub, Annalisa" uniqKey="Schaub A" first="Annalisa" last="Schaub">Annalisa Schaub</name><affiliation><nlm:aff id="aff1"><institution>Institute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation><affiliation><nlm:aff id="aff2"><institution>Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Jones, Alisha N" sort="Jones, Alisha N" uniqKey="Jones A" first="Alisha N." last="Jones">Alisha N. Jones</name><affiliation><nlm:aff id="aff3"><institution>Institute of Structural Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation><affiliation><nlm:aff id="aff4"><institution>Center for Integrated Protein Science Munich, Chemistry Department, Technical University of Munich, Garching, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Wolf, Christine" sort="Wolf, Christine" uniqKey="Wolf C" first="Christine" last="Wolf">Christine Wolf</name><affiliation><nlm:aff id="aff5"><institution>Institute of Environmental Medicine, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Behrens, Gesine" sort="Behrens, Gesine" uniqKey="Behrens G" first="Gesine" last="Behrens">Gesine Behrens</name><affiliation><nlm:aff id="aff6"><institution>Institute for Immunology, Biomedical Center, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Lichti, Johannes" sort="Lichti, Johannes" uniqKey="Lichti J" first="Johannes" last="Lichti">Johannes Lichti</name><affiliation><nlm:aff id="aff1"><institution>Institute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Essig, Katharina" sort="Essig, Katharina" uniqKey="Essig K" first="Katharina" last="Essig">Katharina Essig</name><affiliation><nlm:aff id="aff7"><institution>Roche Pharma Research and Early Development, Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Macht, Anna" sort="Macht, Anna" uniqKey="Macht A" first="Anna" last="Macht">Anna Macht</name><affiliation><nlm:aff id="aff1"><institution>Institute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Pircher, Joachim" sort="Pircher, Joachim" uniqKey="Pircher J" first="Joachim" last="Pircher">Joachim Pircher</name><affiliation><nlm:aff id="aff8"><institution>Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Ludwig-Maximilians-University, Munich, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Ehrlich, Andreas" sort="Ehrlich, Andreas" uniqKey="Ehrlich A" first="Andreas" last="Ehrlich">Andreas Ehrlich</name><affiliation><nlm:aff id="aff8"><institution>Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Ludwig-Maximilians-University, Munich, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Davari, Kathrin" sort="Davari, Kathrin" uniqKey="Davari K" first="Kathrin" last="Davari">Kathrin Davari</name><affiliation><nlm:aff id="aff9"><institution>Medigene Immunotherapies, Planegg-Martinsried, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Chauhan, Dhruv" sort="Chauhan, Dhruv" uniqKey="Chauhan D" first="Dhruv" last="Chauhan">Dhruv Chauhan</name><affiliation><nlm:aff id="aff10"><institution>Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Busch, Benjamin" sort="Busch, Benjamin" uniqKey="Busch B" first="Benjamin" last="Busch">Benjamin Busch</name><affiliation><nlm:aff id="aff11"><institution>Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, Ludwig-Maximilians-Universität München, Munich, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Wurst, Wolfgang" sort="Wurst, Wolfgang" uniqKey="Wurst W" first="Wolfgang" last="Wurst">Wolfgang Wurst</name><affiliation><nlm:aff id="aff12"><institution>Institute of Developmental Genetics, Helmholtz Zentrum München, Munich, Germany</institution></nlm:aff></affiliation><affiliation><nlm:aff id="aff13"><institution>Technische Universität München-Weihenstephan, Neuherberg-Munich, Germany</institution></nlm:aff></affiliation><affiliation><nlm:aff id="aff14"><institution>German Center for Neurodegenerative Diseases, Munich, Germany</institution></nlm:aff></affiliation><affiliation><nlm:aff id="aff15"><institution>Munich Cluster for Systems Neurology, Munich, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Feederle, Regina" sort="Feederle, Regina" uniqKey="Feederle R" first="Regina" last="Feederle">Regina Feederle</name><affiliation><nlm:aff id="aff16"><institution>Monoclonal Antibody Core Facility, Institute for Diabetes and Obesity, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Feuchtinger, Annette" sort="Feuchtinger, Annette" uniqKey="Feuchtinger A" first="Annette" last="Feuchtinger">Annette Feuchtinger</name><affiliation><nlm:aff id="aff17"><institution>Research Unit Analytical Pathology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Tschop, Matthias H" sort="Tschop, Matthias H" uniqKey="Tschop M" first="Matthias H." last="Tschöp">Matthias H. Tschöp</name><affiliation><nlm:aff id="aff1"><institution>Institute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation><affiliation><nlm:aff id="aff18"><institution>Division of Metabolic Diseases, Department of Medicine, Technische Universität München, Munich, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Friedel, Caroline C" sort="Friedel, Caroline C" uniqKey="Friedel C" first="Caroline C." last="Friedel">Caroline C. Friedel</name><affiliation><nlm:aff id="aff19"><institution>Institute for Informatics, Ludwig-Maximilians-Universität München, Munich, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Hauck, Stefanie M" sort="Hauck, Stefanie M" uniqKey="Hauck S" first="Stefanie M." last="Hauck">Stefanie M. Hauck</name><affiliation><nlm:aff id="aff20"><institution>Research Unit Protein Science, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Sattler, Michael" sort="Sattler, Michael" uniqKey="Sattler M" first="Michael" last="Sattler">Michael Sattler</name><affiliation><nlm:aff id="aff3"><institution>Institute of Structural Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation><affiliation><nlm:aff id="aff4"><institution>Center for Integrated Protein Science Munich, Chemistry Department, Technical University of Munich, Garching, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Geerlof, Arie" sort="Geerlof, Arie" uniqKey="Geerlof A" first="Arie" last="Geerlof">Arie Geerlof</name><affiliation><nlm:aff id="aff3"><institution>Institute of Structural Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Hornung, Veit" sort="Hornung, Veit" uniqKey="Hornung V" first="Veit" last="Hornung">Veit Hornung</name><affiliation><nlm:aff id="aff10"><institution>Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Heissmeyer, Vigo" sort="Heissmeyer, Vigo" uniqKey="Heissmeyer V" first="Vigo" last="Heissmeyer">Vigo Heissmeyer</name><affiliation><nlm:aff id="aff6"><institution>Institute for Immunology, Biomedical Center, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany</institution></nlm:aff></affiliation><affiliation><nlm:aff id="aff21"><institution>Research Unit Molecular Immune Regulation, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Schulz, Christian" sort="Schulz, Christian" uniqKey="Schulz C" first="Christian" last="Schulz">Christian Schulz</name><affiliation><nlm:aff id="aff8"><institution>Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Ludwig-Maximilians-University, Munich, Germany</institution></nlm:aff></affiliation><affiliation><nlm:aff id="aff22"><institution>German Center for Cardiovascular Research, partner site Munich Heart Alliance, Munich, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Heikenwalder, Mathias" sort="Heikenwalder, Mathias" uniqKey="Heikenwalder M" first="Mathias" last="Heikenwalder">Mathias Heikenwalder</name><affiliation><nlm:aff id="aff23"><institution>Division of Chronic Inflammation and Cancer (F180), German Cancer Research Center, Heidelberg, Germany</institution></nlm:aff></affiliation></author><author><name sortKey="Glasmacher, Elke" sort="Glasmacher, Elke" uniqKey="Glasmacher E" first="Elke" last="Glasmacher">Elke Glasmacher</name><affiliation><nlm:aff id="aff1"><institution>Institute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany</institution></nlm:aff></affiliation><affiliation><nlm:aff id="aff7"><institution>Roche Pharma Research and Early Development, Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germany</institution></nlm:aff></affiliation></author></analytic><series><title level="j">The Journal of Experimental Medicine</title><idno type="ISSN">0022-1007</idno><idno type="eISSN">1540-9538</idno><imprint><date when="2019">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>von Gamm et al. demonstrate that mice deficient for the RNase Regnase-3 (Zc3h12c) develop hypertrophic lymph nodes and a systemic interferon response. Regnase-3 is a functional RNase that acts in myeloid cells upon IRF signaling, suggesting it to be an evolutionary counterpart to Regnase-1.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Abram, C L" uniqKey="Abram C">C.L. Abram</name></author><author><name sortKey="Roberge, G L" uniqKey="Roberge G">G.L. Roberge</name></author><author><name sortKey="Hu, Y" uniqKey="Hu Y">Y. Hu</name></author><author><name sortKey="Lowell, C A" uniqKey="Lowell C">C.A. Lowell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Akira, S" uniqKey="Akira S">S. Akira</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Amit, I" uniqKey="Amit I">I. Amit</name></author><author><name sortKey="Winter, D R" uniqKey="Winter D">D.R. Winter</name></author><author><name sortKey="Jung, S" uniqKey="Jung S">S. Jung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Boratyn, E" uniqKey="Boratyn E">E. Boratyn</name></author><author><name sortKey="Nowak, I" uniqKey="Nowak I">I. Nowak</name></author><author><name sortKey="Horwacik, I" uniqKey="Horwacik I">I. Horwacik</name></author><author><name sortKey="Durbas, M" uniqKey="Durbas M">M. Durbas</name></author><author><name sortKey="Mistarz, A" uniqKey="Mistarz A">A. Mistarz</name></author><author><name sortKey="Kukla, M" uniqKey="Kukla M">M. Kukla</name></author><author><name sortKey="Kacz Wka, P" uniqKey="Kacz Wka P">P. Kaczówka</name></author><author><name sortKey="Lastowska, M" uniqKey="Lastowska M">M. Łastowska</name></author><author><name sortKey="Jura, J" uniqKey="Jura J">J. Jura</name></author><author><name sortKey="Rokita, H" uniqKey="Rokita H">H. Rokita</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Boratyn, E" uniqKey="Boratyn E">E. Boratyn</name></author><author><name sortKey="Nowak, I" uniqKey="Nowak I">I. Nowak</name></author><author><name sortKey="Durbas, M" uniqKey="Durbas M">M. Durbas</name></author><author><name sortKey="Horwacik, I" uniqKey="Horwacik I">I. Horwacik</name></author><author><name sortKey="Sawicka, A" uniqKey="Sawicka A">A. Sawicka</name></author><author><name sortKey="Rokita, H" uniqKey="Rokita H">H. Rokita</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eden, E" uniqKey="Eden E">E. Eden</name></author><author><name sortKey="Navon, R" uniqKey="Navon R">R. Navon</name></author><author><name sortKey="Steinfeld, I" uniqKey="Steinfeld I">I. Steinfeld</name></author><author><name sortKey="Lipson, D" uniqKey="Lipson D">D. Lipson</name></author><author><name sortKey="Yakhini, Z" uniqKey="Yakhini Z">Z. Yakhini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Faltynek, C R" uniqKey="Faltynek C">C.R. Faltynek</name></author><author><name sortKey="Oppenheim, J J" uniqKey="Oppenheim J">J.J. Oppenheim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Feederle, R" uniqKey="Feederle R">R. Feederle</name></author><author><name sortKey="Gerber, J K" uniqKey="Gerber J">J.K. Gerber</name></author><author><name sortKey="Middleton, A" uniqKey="Middleton A">A. Middleton</name></author><author><name sortKey="Northrup, E" uniqKey="Northrup E">E. Northrup</name></author><author><name sortKey="Kist, R" uniqKey="Kist R">R. Kist</name></author><author><name sortKey="Kremmer, E" uniqKey="Kremmer E">E. Kremmer</name></author><author><name sortKey="Peters, H" uniqKey="Peters H">H. Peters</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Feuchtinger, A" uniqKey="Feuchtinger A">A. Feuchtinger</name></author><author><name sortKey="Stiehler, T" uniqKey="Stiehler T">T. Stiehler</name></author><author><name sortKey="Jutting, U" uniqKey="Jutting U">U. Jütting</name></author><author><name sortKey="Marjanovic, G" uniqKey="Marjanovic G">G. Marjanovic</name></author><author><name sortKey="Luber, B" uniqKey="Luber B">B. Luber</name></author><author><name sortKey="Langer, R" uniqKey="Langer R">R. Langer</name></author><author><name sortKey="Walch, A" uniqKey="Walch A">A. Walch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Garg, A V" uniqKey="Garg A">A.V. Garg</name></author><author><name sortKey="Amatya, N" uniqKey="Amatya N">N. Amatya</name></author><author><name sortKey="Chen, K" uniqKey="Chen K">K. Chen</name></author><author><name sortKey="Cruz, J A" uniqKey="Cruz J">J.A. Cruz</name></author><author><name sortKey="Grover, P" uniqKey="Grover P">P. Grover</name></author><author><name sortKey="Whibley, N" uniqKey="Whibley N">N. Whibley</name></author><author><name sortKey="Conti, H R" uniqKey="Conti H">H.R. Conti</name></author><author><name sortKey="Hernandez Mir, G" uniqKey="Hernandez Mir G">G. Hernandez Mir</name></author><author><name sortKey="Sirakova, T" uniqKey="Sirakova T">T. Sirakova</name></author><author><name sortKey="Childs, E C" uniqKey="Childs E">E.C. Childs</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gerstberger, S" uniqKey="Gerstberger S">S. Gerstberger</name></author><author><name sortKey="Hafner, M" uniqKey="Hafner M">M. Hafner</name></author><author><name sortKey="Tuschl, T" uniqKey="Tuschl T">T. Tuschl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Glasmacher, E" uniqKey="Glasmacher E">E. Glasmacher</name></author><author><name sortKey="Hoefig, K P" uniqKey="Hoefig K">K.P. Hoefig</name></author><author><name sortKey="Vogel, K U" uniqKey="Vogel K">K.U. Vogel</name></author><author><name sortKey="Rath, N" uniqKey="Rath N">N. Rath</name></author><author><name sortKey="Du, L" uniqKey="Du L">L. Du</name></author><author><name sortKey="Wolf, C" uniqKey="Wolf C">C. Wolf</name></author><author><name sortKey="Kremmer, E" uniqKey="Kremmer E">E. Kremmer</name></author><author><name sortKey="Wang, X" uniqKey="Wang X">X. Wang</name></author><author><name sortKey="Heissmeyer, V" uniqKey="Heissmeyer V">V. Heissmeyer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Habacher, C" uniqKey="Habacher C">C. Habacher</name></author><author><name sortKey="Ciosk, R" uniqKey="Ciosk R">R. Ciosk</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hayden, M S" uniqKey="Hayden M">M.S. Hayden</name></author><author><name sortKey="Ghosh, S" uniqKey="Ghosh S">S. Ghosh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Heikenwalder, M" uniqKey="Heikenwalder M">M. Heikenwalder</name></author><author><name sortKey="Polymenidou, M" uniqKey="Polymenidou M">M. Polymenidou</name></author><author><name sortKey="Junt, T" uniqKey="Junt T">T. Junt</name></author><author><name sortKey="Sigurdson, C" uniqKey="Sigurdson C">C. Sigurdson</name></author><author><name sortKey="Wagner, H" uniqKey="Wagner H">H. Wagner</name></author><author><name sortKey="Akira, S" uniqKey="Akira S">S. Akira</name></author><author><name sortKey="Zinkernagel, R" uniqKey="Zinkernagel R">R. Zinkernagel</name></author><author><name sortKey="Aguzzi, A" uniqKey="Aguzzi A">A. Aguzzi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Heissmeyer, V" uniqKey="Heissmeyer V">V. Heissmeyer</name></author><author><name sortKey="Vogel, K U" uniqKey="Vogel K">K.U. Vogel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hume, D A" uniqKey="Hume D">D.A. Hume</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Italiani, P" uniqKey="Italiani P">P. Italiani</name></author><author><name sortKey="Boraschi, D" uniqKey="Boraschi D">D. Boraschi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Iwanaszko, M" uniqKey="Iwanaszko M">M. Iwanaszko</name></author><author><name sortKey="Kimmel, M" uniqKey="Kimmel M">M. Kimmel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Iwasaki, H" uniqKey="Iwasaki H">H. Iwasaki</name></author><author><name sortKey="Takeuchi, O" uniqKey="Takeuchi O">O. Takeuchi</name></author><author><name sortKey="Teraguchi, S" uniqKey="Teraguchi S">S. Teraguchi</name></author><author><name sortKey="Matsushita, K" uniqKey="Matsushita K">K. Matsushita</name></author><author><name sortKey="Uehata, T" uniqKey="Uehata T">T. Uehata</name></author><author><name sortKey="Kuniyoshi, K" uniqKey="Kuniyoshi K">K. Kuniyoshi</name></author><author><name sortKey="Satoh, T" uniqKey="Satoh T">T. Satoh</name></author><author><name sortKey="Saitoh, T" uniqKey="Saitoh T">T. Saitoh</name></author><author><name sortKey="Matsushita, M" uniqKey="Matsushita M">M. Matsushita</name></author><author><name sortKey="Standley, D M" uniqKey="Standley D">D.M. Standley</name></author><author><name sortKey="Akira, S" uniqKey="Akira S">S. Akira</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jackson, S W" uniqKey="Jackson S">S.W. Jackson</name></author><author><name sortKey="Jacobs, H M" uniqKey="Jacobs H">H.M. Jacobs</name></author><author><name sortKey="Arkatkar, T" uniqKey="Arkatkar T">T. Arkatkar</name></author><author><name sortKey="Dam, E M" uniqKey="Dam E">E.M. Dam</name></author><author><name sortKey="Scharping, N E" uniqKey="Scharping N">N.E. Scharping</name></author><author><name sortKey="Kolhatkar, N S" uniqKey="Kolhatkar N">N.S. Kolhatkar</name></author><author><name sortKey="Hou, B" uniqKey="Hou B">B. Hou</name></author><author><name sortKey="Buckner, J H" uniqKey="Buckner J">J.H. Buckner</name></author><author><name sortKey="Rawlings, D J" uniqKey="Rawlings D">D.J. Rawlings</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jeltsch, K M" uniqKey="Jeltsch K">K.M. Jeltsch</name></author><author><name sortKey="Hu, D" uniqKey="Hu D">D. Hu</name></author><author><name sortKey="Brenner, S" uniqKey="Brenner S">S. Brenner</name></author><author><name sortKey="Zoller, J" uniqKey="Zoller J">J. Zöller</name></author><author><name sortKey="Heinz, G A" uniqKey="Heinz G">G.A. Heinz</name></author><author><name sortKey="Nagel, D" uniqKey="Nagel D">D. Nagel</name></author><author><name sortKey="Vogel, K U" uniqKey="Vogel K">K.U. Vogel</name></author><author><name sortKey="Rehage, N" uniqKey="Rehage N">N. Rehage</name></author><author><name sortKey="Warth, S C" uniqKey="Warth S">S.C. Warth</name></author><author><name sortKey="Edelmann, S L" uniqKey="Edelmann S">S.L. Edelmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuleshov, M V" uniqKey="Kuleshov M">M.V. Kuleshov</name></author><author><name sortKey="Jones, M R" uniqKey="Jones M">M.R. Jones</name></author><author><name sortKey="Rouillard, A D" uniqKey="Rouillard A">A.D. Rouillard</name></author><author><name sortKey="Fernandez, N F" uniqKey="Fernandez N">N.F. Fernandez</name></author><author><name sortKey="Duan, Q" uniqKey="Duan Q">Q. Duan</name></author><author><name sortKey="Wang, Z" uniqKey="Wang Z">Z. Wang</name></author><author><name sortKey="Koplev, S" uniqKey="Koplev S">S. Koplev</name></author><author><name sortKey="Jenkins, S L" uniqKey="Jenkins S">S.L. Jenkins</name></author><author><name sortKey="Jagodnik, K M" uniqKey="Jagodnik K">K.M. Jagodnik</name></author><author><name sortKey="Lachmann, A" uniqKey="Lachmann A">A. Lachmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lasko, P" uniqKey="Lasko P">P. Lasko</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Y" uniqKey="Li Y">Y. Li</name></author><author><name sortKey="Huang, X" uniqKey="Huang X">X. Huang</name></author><author><name sortKey="Huang, S" uniqKey="Huang S">S. Huang</name></author><author><name sortKey="He, H" uniqKey="He H">H. He</name></author><author><name sortKey="Lei, T" uniqKey="Lei T">T. Lei</name></author><author><name sortKey="Saaoud, F" uniqKey="Saaoud F">F. Saaoud</name></author><author><name sortKey="Yu, X Q" uniqKey="Yu X">X.Q. Yu</name></author><author><name sortKey="Melnick, A" uniqKey="Melnick A">A. Melnick</name></author><author><name sortKey="Kumar, A" uniqKey="Kumar A">A. Kumar</name></author><author><name sortKey="Papasian, C J" uniqKey="Papasian C">C.J. Papasian</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liang, J" uniqKey="Liang J">J. Liang</name></author><author><name sortKey="Wang, J" uniqKey="Wang J">J. Wang</name></author><author><name sortKey="Azfer, A" uniqKey="Azfer A">A. Azfer</name></author><author><name sortKey="Song, W" uniqKey="Song W">W. Song</name></author><author><name sortKey="Tromp, G" uniqKey="Tromp G">G. Tromp</name></author><author><name sortKey="Kolattukudy, P E" uniqKey="Kolattukudy P">P.E. Kolattukudy</name></author><author><name sortKey="Fu, M" uniqKey="Fu M">M. Fu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liao, Y" uniqKey="Liao Y">Y. Liao</name></author><author><name sortKey="Smyth, G K" uniqKey="Smyth G">G.K. Smyth</name></author><author><name sortKey="Shi, W" uniqKey="Shi W">W. Shi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lichti, J" uniqKey="Lichti J">J. Lichti</name></author><author><name sortKey="Gallus, C" uniqKey="Gallus C">C. Gallus</name></author><author><name sortKey="Glasmacher, E" uniqKey="Glasmacher E">E. Glasmacher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, J" uniqKey="Liu J">J. Liu</name></author><author><name sortKey="Karypis, G" uniqKey="Karypis G">G. Karypis</name></author><author><name sortKey="Hippen, K L" uniqKey="Hippen K">K.L. Hippen</name></author><author><name sortKey="Vegoe, A L" uniqKey="Vegoe A">A.L. Vegoe</name></author><author><name sortKey="Ruiz, P" uniqKey="Ruiz P">P. Ruiz</name></author><author><name sortKey="Gilkeson, G S" uniqKey="Gilkeson G">G.S. Gilkeson</name></author><author><name sortKey="Behrens, T W" uniqKey="Behrens T">T.W. Behrens</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, L" uniqKey="Liu L">L. Liu</name></author><author><name sortKey="Zhou, Z" uniqKey="Zhou Z">Z. Zhou</name></author><author><name sortKey="Huang, S" uniqKey="Huang S">S. Huang</name></author><author><name sortKey="Guo, Y" uniqKey="Guo Y">Y. Guo</name></author><author><name sortKey="Fan, Y" uniqKey="Fan Y">Y. Fan</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J. Zhang</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J. Zhang</name></author><author><name sortKey="Fu, M" uniqKey="Fu M">M. Fu</name></author><author><name sortKey="Chen, Y E" uniqKey="Chen Y">Y.E. Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, S" uniqKey="Liu S">S. Liu</name></author><author><name sortKey="Cai, X" uniqKey="Cai X">X. Cai</name></author><author><name sortKey="Wu, J" uniqKey="Wu J">J. Wu</name></author><author><name sortKey="Cong, Q" uniqKey="Cong Q">Q. Cong</name></author><author><name sortKey="Chen, X" uniqKey="Chen X">X. Chen</name></author><author><name sortKey="Li, T" uniqKey="Li T">T. Li</name></author><author><name sortKey="Du, F" uniqKey="Du F">F. Du</name></author><author><name sortKey="Ren, J" uniqKey="Ren J">J. Ren</name></author><author><name sortKey="Wu, Y T" uniqKey="Wu Y">Y.T. Wu</name></author><author><name sortKey="Grishin, N V" uniqKey="Grishin N">N.V. Grishin</name></author><author><name sortKey="Chen, Z J" uniqKey="Chen Z">Z.J. Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lu, W" uniqKey="Lu W">W. Lu</name></author><author><name sortKey="Ning, H" uniqKey="Ning H">H. Ning</name></author><author><name sortKey="Gu, L" uniqKey="Gu L">L. Gu</name></author><author><name sortKey="Peng, H" uniqKey="Peng H">H. Peng</name></author><author><name sortKey="Wang, Q" uniqKey="Wang Q">Q. Wang</name></author><author><name sortKey="Hou, R" uniqKey="Hou R">R. Hou</name></author><author><name sortKey="Fu, M" uniqKey="Fu M">M. Fu</name></author><author><name sortKey="Hoft, D F" uniqKey="Hoft D">D.F. Hoft</name></author><author><name sortKey="Liu, J" uniqKey="Liu J">J. Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mao, R" uniqKey="Mao R">R. Mao</name></author><author><name sortKey="Yang, R" uniqKey="Yang R">R. Yang</name></author><author><name sortKey="Chen, X" uniqKey="Chen X">X. Chen</name></author><author><name sortKey="Harhaj, E W" uniqKey="Harhaj E">E.W. Harhaj</name></author><author><name sortKey="Wang, X" uniqKey="Wang X">X. Wang</name></author><author><name sortKey="Fan, Y" uniqKey="Fan Y">Y. Fan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Matsushita, K" uniqKey="Matsushita K">K. Matsushita</name></author><author><name sortKey="Takeuchi, O" uniqKey="Takeuchi O">O. Takeuchi</name></author><author><name sortKey="Standley, D M" uniqKey="Standley D">D.M. Standley</name></author><author><name sortKey="Kumagai, Y" uniqKey="Kumagai Y">Y. Kumagai</name></author><author><name sortKey="Kawagoe, T" uniqKey="Kawagoe T">T. Kawagoe</name></author><author><name sortKey="Miyake, T" uniqKey="Miyake T">T. Miyake</name></author><author><name sortKey="Satoh, T" uniqKey="Satoh T">T. Satoh</name></author><author><name sortKey="Kato, H" uniqKey="Kato H">H. Kato</name></author><author><name sortKey="Tsujimura, T" uniqKey="Tsujimura T">T. Tsujimura</name></author><author><name sortKey="Nakamura, H" uniqKey="Nakamura H">H. Nakamura</name></author><author><name sortKey="Akira, S" uniqKey="Akira S">S. Akira</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Meissl, K" uniqKey="Meissl K">K. Meissl</name></author><author><name sortKey="Macho Maschler, S" uniqKey="Macho Maschler S">S. Macho-Maschler</name></author><author><name sortKey="Muller, M" uniqKey="Muller M">M. Müller</name></author><author><name sortKey="Strobl, B" uniqKey="Strobl B">B. Strobl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Minagawa, K" uniqKey="Minagawa K">K. Minagawa</name></author><author><name sortKey="Wakahashi, K" uniqKey="Wakahashi K">K. Wakahashi</name></author><author><name sortKey="Kawano, H" uniqKey="Kawano H">H. Kawano</name></author><author><name sortKey="Nishikawa, S" uniqKey="Nishikawa S">S. Nishikawa</name></author><author><name sortKey="Fukui, C" uniqKey="Fukui C">C. Fukui</name></author><author><name sortKey="Kawano, Y" uniqKey="Kawano Y">Y. Kawano</name></author><author><name sortKey="Asada, N" uniqKey="Asada N">N. Asada</name></author><author><name sortKey="Sato, M" uniqKey="Sato M">M. Sato</name></author><author><name sortKey="Sada, A" uniqKey="Sada A">A. Sada</name></author><author><name sortKey="Katayama, Y" uniqKey="Katayama Y">Y. Katayama</name></author><author><name sortKey="Matsui, T" uniqKey="Matsui T">T. Matsui</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mino, T" uniqKey="Mino T">T. Mino</name></author><author><name sortKey="Takeuchi, O" uniqKey="Takeuchi O">O. Takeuchi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mino, T" uniqKey="Mino T">T. Mino</name></author><author><name sortKey="Murakawa, Y" uniqKey="Murakawa Y">Y. Murakawa</name></author><author><name sortKey="Fukao, A" uniqKey="Fukao A">A. Fukao</name></author><author><name sortKey="Vandenbon, A" uniqKey="Vandenbon A">A. Vandenbon</name></author><author><name sortKey="Wessels, H H" uniqKey="Wessels H">H.H. Wessels</name></author><author><name sortKey="Ori, D" uniqKey="Ori D">D. Ori</name></author><author><name sortKey="Uehata, T" uniqKey="Uehata T">T. Uehata</name></author><author><name sortKey="Tartey, S" uniqKey="Tartey S">S. Tartey</name></author><author><name sortKey="Akira, S" uniqKey="Akira S">S. Akira</name></author><author><name sortKey="Suzuki, Y" uniqKey="Suzuki Y">Y. Suzuki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Oeckinghaus, A" uniqKey="Oeckinghaus A">A. Oeckinghaus</name></author><author><name sortKey="Ghosh, S" uniqKey="Ghosh S">S. Ghosh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Okabe, Y" uniqKey="Okabe Y">Y. Okabe</name></author><author><name sortKey="Medzhitov, R" uniqKey="Medzhitov R">R. Medzhitov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Paul, W E" uniqKey="Paul W">W.E. Paul</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Paun, A" uniqKey="Paun A">A. Paun</name></author><author><name sortKey="Pitha, P M" uniqKey="Pitha P">P.M. Pitha</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pichlmair, A" uniqKey="Pichlmair A">A. Pichlmair</name></author><author><name sortKey="Reis E Sousa, C" uniqKey="Reis E Sousa C">C. Reis e Sousa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Redecke, V" uniqKey="Redecke V">V. Redecke</name></author><author><name sortKey="Wu, R" uniqKey="Wu R">R. Wu</name></author><author><name sortKey="Zhou, J" uniqKey="Zhou J">J. Zhou</name></author><author><name sortKey="Finkelstein, D" uniqKey="Finkelstein D">D. Finkelstein</name></author><author><name sortKey="Chaturvedi, V" uniqKey="Chaturvedi V">V. Chaturvedi</name></author><author><name sortKey="High, A A" uniqKey="High A">A.A. High</name></author><author><name sortKey="H Cker, H" uniqKey="H Cker H">H. Häcker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Robinson, M D" uniqKey="Robinson M">M.D. Robinson</name></author><author><name sortKey="Mccarthy, D J" uniqKey="Mccarthy D">D.J. McCarthy</name></author><author><name sortKey="Smyth, G K" uniqKey="Smyth G">G.K. Smyth</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sanjuan, M A" uniqKey="Sanjuan M">M.A. Sanjuan</name></author><author><name sortKey="Dillon, C P" uniqKey="Dillon C">C.P. Dillon</name></author><author><name sortKey="Tait, S W" uniqKey="Tait S">S.W. Tait</name></author><author><name sortKey="Moshiach, S" uniqKey="Moshiach S">S. Moshiach</name></author><author><name sortKey="Dorsey, F" uniqKey="Dorsey F">F. Dorsey</name></author><author><name sortKey="Connell, S" uniqKey="Connell S">S. Connell</name></author><author><name sortKey="Komatsu, M" uniqKey="Komatsu M">M. Komatsu</name></author><author><name sortKey="Tanaka, K" uniqKey="Tanaka K">K. Tanaka</name></author><author><name sortKey="Cleveland, J L" uniqKey="Cleveland J">J.L. Cleveland</name></author><author><name sortKey="Withoff, S" uniqKey="Withoff S">S. Withoff</name></author><author><name sortKey="Green, D R" uniqKey="Green D">D.R. Green</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schulz, C" uniqKey="Schulz C">C. Schulz</name></author><author><name sortKey="Gomez Perdiguero, E" uniqKey="Gomez Perdiguero E">E. Gomez Perdiguero</name></author><author><name sortKey="Chorro, L" uniqKey="Chorro L">L. Chorro</name></author><author><name sortKey="Szabo Rogers, H" uniqKey="Szabo Rogers H">H. Szabo-Rogers</name></author><author><name sortKey="Cagnard, N" uniqKey="Cagnard N">N. Cagnard</name></author><author><name sortKey="Kierdorf, K" uniqKey="Kierdorf K">K. Kierdorf</name></author><author><name sortKey="Prinz, M" uniqKey="Prinz M">M. Prinz</name></author><author><name sortKey="Wu, B" uniqKey="Wu B">B. Wu</name></author><author><name sortKey="Jacobsen, S E" uniqKey="Jacobsen S">S.E. Jacobsen</name></author><author><name sortKey="Pollard, J W" uniqKey="Pollard J">J.W. Pollard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sha, W C" uniqKey="Sha W">W.C. Sha</name></author><author><name sortKey="Liou, H C" uniqKey="Liou H">H.C. Liou</name></author><author><name sortKey="Tuomanen, E I" uniqKey="Tuomanen E">E.I. Tuomanen</name></author><author><name sortKey="Baltimore, D" uniqKey="Baltimore D">D. Baltimore</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Skalniak, A" uniqKey="Skalniak A">A. Skalniak</name></author><author><name sortKey="Boratyn, E" uniqKey="Boratyn E">E. Boratyn</name></author><author><name sortKey="Tyrkalska, S D" uniqKey="Tyrkalska S">S.D. Tyrkalska</name></author><author><name sortKey="Horwacik, I" uniqKey="Horwacik I">I. Horwacik</name></author><author><name sortKey="Durbas, M" uniqKey="Durbas M">M. Durbas</name></author><author><name sortKey="Lastowska, M" uniqKey="Lastowska M">M. Lastowska</name></author><author><name sortKey="Jura, J" uniqKey="Jura J">J. Jura</name></author><author><name sortKey="Rokita, H" uniqKey="Rokita H">H. Rokita</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stetson, D B" uniqKey="Stetson D">D.B. Stetson</name></author><author><name sortKey="Medzhitov, R" uniqKey="Medzhitov R">R. Medzhitov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Suk, F M" uniqKey="Suk F">F.M. Suk</name></author><author><name sortKey="Chang, C C" uniqKey="Chang C">C.C. Chang</name></author><author><name sortKey="Lin, R J" uniqKey="Lin R">R.J. Lin</name></author><author><name sortKey="Lin, S Y" uniqKey="Lin S">S.Y. Lin</name></author><author><name sortKey="Chen, Y T" uniqKey="Chen Y">Y.T. Chen</name></author><author><name sortKey="Liang, Y C" uniqKey="Liang Y">Y.C. Liang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Supek, F" uniqKey="Supek F">F. Supek</name></author><author><name sortKey="Bosnjak, M" uniqKey="Bosnjak M">M. Bošnjak</name></author><author><name sortKey="Skunca, N" uniqKey="Skunca N">N. Škunca</name></author><author><name sortKey="Smuc, T" uniqKey="Smuc T">T. Šmuc</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Suzuki, H I" uniqKey="Suzuki H">H.I. Suzuki</name></author><author><name sortKey="Arase, M" uniqKey="Arase M">M. Arase</name></author><author><name sortKey="Matsuyama, H" uniqKey="Matsuyama H">H. Matsuyama</name></author><author><name sortKey="Choi, Y L" uniqKey="Choi Y">Y.L. Choi</name></author><author><name sortKey="Ueno, T" uniqKey="Ueno T">T. Ueno</name></author><author><name sortKey="Mano, H" uniqKey="Mano H">H. Mano</name></author><author><name sortKey="Sugimoto, K" uniqKey="Sugimoto K">K. Sugimoto</name></author><author><name sortKey="Miyazono, K" uniqKey="Miyazono K">K. Miyazono</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Swamydas, M" uniqKey="Swamydas M">M. Swamydas</name></author><author><name sortKey="Luo, Y" uniqKey="Luo Y">Y. Luo</name></author><author><name sortKey="Dorf, M E" uniqKey="Dorf M">M.E. Dorf</name></author><author><name sortKey="Lionakis, M S" uniqKey="Lionakis M">M.S. Lionakis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tsoi, L C" uniqKey="Tsoi L">L.C. Tsoi</name></author><author><name sortKey="Spain, S L" uniqKey="Spain S">S.L. Spain</name></author><author><name sortKey="Knight, J" uniqKey="Knight J">J. Knight</name></author><author><name sortKey="Ellinghaus, E" uniqKey="Ellinghaus E">E. Ellinghaus</name></author><author><name sortKey="Stuart, P E" uniqKey="Stuart P">P.E. Stuart</name></author><author><name sortKey="Capon, F" uniqKey="Capon F">F. Capon</name></author><author><name sortKey="Ding, J" uniqKey="Ding J">J. Ding</name></author><author><name sortKey="Li, Y" uniqKey="Li Y">Y. Li</name></author><author><name sortKey="Tejasvi, T" uniqKey="Tejasvi T">T. Tejasvi</name></author><author><name sortKey="Gudjonsson, J E" uniqKey="Gudjonsson J">J.E. Gudjonsson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Uehata, T" uniqKey="Uehata T">T. Uehata</name></author><author><name sortKey="Akira, S" uniqKey="Akira S">S. Akira</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Uehata, T" uniqKey="Uehata T">T. Uehata</name></author><author><name sortKey="Iwasaki, H" uniqKey="Iwasaki H">H. Iwasaki</name></author><author><name sortKey="Vandenbon, A" uniqKey="Vandenbon A">A. Vandenbon</name></author><author><name sortKey="Matsushita, K" uniqKey="Matsushita K">K. Matsushita</name></author><author><name sortKey="Hernandez Cuellar, E" uniqKey="Hernandez Cuellar E">E. Hernandez-Cuellar</name></author><author><name sortKey="Kuniyoshi, K" uniqKey="Kuniyoshi K">K. Kuniyoshi</name></author><author><name sortKey="Satoh, T" uniqKey="Satoh T">T. Satoh</name></author><author><name sortKey="Mino, T" uniqKey="Mino T">T. Mino</name></author><author><name sortKey="Suzuki, Y" uniqKey="Suzuki Y">Y. Suzuki</name></author><author><name sortKey="Standley, D M" uniqKey="Standley D">D.M. Standley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Varet, H" uniqKey="Varet H">H. Varet</name></author><author><name sortKey="Brillet Gueguen, L" uniqKey="Brillet Gueguen L">L. Brillet-Guéguen</name></author><author><name sortKey="Coppee, J Y" uniqKey="Coppee J">J.Y. Coppée</name></author><author><name sortKey="Dillies, M A" uniqKey="Dillies M">M.A. Dillies</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vinuesa, C G" uniqKey="Vinuesa C">C.G. Vinuesa</name></author><author><name sortKey="Cook, M C" uniqKey="Cook M">M.C. Cook</name></author><author><name sortKey="Angelucci, C" uniqKey="Angelucci C">C. Angelucci</name></author><author><name sortKey="Athanasopoulos, V" uniqKey="Athanasopoulos V">V. Athanasopoulos</name></author><author><name sortKey="Rui, L" uniqKey="Rui L">L. Rui</name></author><author><name sortKey="Hill, K M" uniqKey="Hill K">K.M. Hill</name></author><author><name sortKey="Yu, D" uniqKey="Yu D">D. Yu</name></author><author><name sortKey="Domaschenz, H" uniqKey="Domaschenz H">H. Domaschenz</name></author><author><name sortKey="Whittle, B" uniqKey="Whittle B">B. Whittle</name></author><author><name sortKey="Lambe, T" uniqKey="Lambe T">T. Lambe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wack, A" uniqKey="Wack A">A. Wack</name></author><author><name sortKey="Terczy Ska Dyla, E" uniqKey="Terczy Ska Dyla E">E. Terczyńska-Dyla</name></author><author><name sortKey="Hartmann, R" uniqKey="Hartmann R">R. Hartmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, G G" uniqKey="Wang G">G.G. Wang</name></author><author><name sortKey="Calvo, K R" uniqKey="Calvo K">K.R. Calvo</name></author><author><name sortKey="Pasillas, M P" uniqKey="Pasillas M">M.P. Pasillas</name></author><author><name sortKey="Sykes, D B" uniqKey="Sykes D">D.B. Sykes</name></author><author><name sortKey="H Cker, H" uniqKey="H Cker H">H. Häcker</name></author><author><name sortKey="Kamps, M P" uniqKey="Kamps M">M.P. Kamps</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, R" uniqKey="Yang R">R. Yang</name></author><author><name sortKey="Wu, Y" uniqKey="Wu Y">Y. Wu</name></author><author><name sortKey="Ming, Y" uniqKey="Ming Y">Y. Ming</name></author><author><name sortKey="Xu, Y" uniqKey="Xu Y">Y. Xu</name></author><author><name sortKey="Wang, S" uniqKey="Wang S">S. Wang</name></author><author><name sortKey="Shen, J" uniqKey="Shen J">J. Shen</name></author><author><name sortKey="Wang, C" uniqKey="Wang C">C. Wang</name></author><author><name sortKey="Chen, X" uniqKey="Chen X">X. Chen</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name></author><author><name sortKey="Mao, R" uniqKey="Mao R">R. Mao</name></author><author><name sortKey="Fan, Y" uniqKey="Fan Y">Y. Fan</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list></list><tree><noCountry><name sortKey="Behrens, Gesine" sort="Behrens, Gesine" uniqKey="Behrens G" first="Gesine" last="Behrens">Gesine Behrens</name><name sortKey="Busch, Benjamin" sort="Busch, Benjamin" uniqKey="Busch B" first="Benjamin" last="Busch">Benjamin Busch</name><name sortKey="Chauhan, Dhruv" sort="Chauhan, Dhruv" uniqKey="Chauhan D" first="Dhruv" last="Chauhan">Dhruv Chauhan</name><name sortKey="Davari, Kathrin" sort="Davari, Kathrin" uniqKey="Davari K" first="Kathrin" last="Davari">Kathrin Davari</name><name sortKey="Ehrlich, Andreas" sort="Ehrlich, Andreas" uniqKey="Ehrlich A" first="Andreas" last="Ehrlich">Andreas Ehrlich</name><name sortKey="Essig, Katharina" sort="Essig, Katharina" uniqKey="Essig K" first="Katharina" last="Essig">Katharina Essig</name><name sortKey="Feederle, Regina" sort="Feederle, Regina" uniqKey="Feederle R" first="Regina" last="Feederle">Regina Feederle</name><name sortKey="Feuchtinger, Annette" sort="Feuchtinger, Annette" uniqKey="Feuchtinger A" first="Annette" last="Feuchtinger">Annette Feuchtinger</name><name sortKey="Friedel, Caroline C" sort="Friedel, Caroline C" uniqKey="Friedel C" first="Caroline C." last="Friedel">Caroline C. Friedel</name><name sortKey="Geerlof, Arie" sort="Geerlof, Arie" uniqKey="Geerlof A" first="Arie" last="Geerlof">Arie Geerlof</name><name sortKey="Glasmacher, Elke" sort="Glasmacher, Elke" uniqKey="Glasmacher E" first="Elke" last="Glasmacher">Elke Glasmacher</name><name sortKey="Hauck, Stefanie M" sort="Hauck, Stefanie M" uniqKey="Hauck S" first="Stefanie M." last="Hauck">Stefanie M. Hauck</name><name sortKey="Heikenwalder, Mathias" sort="Heikenwalder, Mathias" uniqKey="Heikenwalder M" first="Mathias" last="Heikenwalder">Mathias Heikenwalder</name><name sortKey="Heissmeyer, Vigo" sort="Heissmeyer, Vigo" uniqKey="Heissmeyer V" first="Vigo" last="Heissmeyer">Vigo Heissmeyer</name><name sortKey="Hornung, Veit" sort="Hornung, Veit" uniqKey="Hornung V" first="Veit" last="Hornung">Veit Hornung</name><name sortKey="Jones, Alisha N" sort="Jones, Alisha N" uniqKey="Jones A" first="Alisha N." last="Jones">Alisha N. Jones</name><name sortKey="Lichti, Johannes" sort="Lichti, Johannes" uniqKey="Lichti J" first="Johannes" last="Lichti">Johannes Lichti</name><name sortKey="Macht, Anna" sort="Macht, Anna" uniqKey="Macht A" first="Anna" last="Macht">Anna Macht</name><name sortKey="Pircher, Joachim" sort="Pircher, Joachim" uniqKey="Pircher J" first="Joachim" last="Pircher">Joachim Pircher</name><name sortKey="Sattler, Michael" sort="Sattler, Michael" uniqKey="Sattler M" first="Michael" last="Sattler">Michael Sattler</name><name sortKey="Schaub, Annalisa" sort="Schaub, Annalisa" uniqKey="Schaub A" first="Annalisa" last="Schaub">Annalisa Schaub</name><name sortKey="Schulz, Christian" sort="Schulz, Christian" uniqKey="Schulz C" first="Christian" last="Schulz">Christian Schulz</name><name sortKey="Tschop, Matthias H" sort="Tschop, Matthias H" uniqKey="Tschop M" first="Matthias H." last="Tschöp">Matthias H. Tschöp</name><name sortKey="Von Gamm, Matthias" sort="Von Gamm, Matthias" uniqKey="Von Gamm M" first="Matthias" last="Von Gamm">Matthias Von Gamm</name><name sortKey="Wolf, Christine" sort="Wolf, Christine" uniqKey="Wolf C" first="Christine" last="Wolf">Christine Wolf</name><name sortKey="Wurst, Wolfgang" sort="Wurst, Wolfgang" uniqKey="Wurst W" first="Wolfgang" last="Wurst">Wolfgang Wurst</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000754 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000754 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= ChloroquineV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:6605757
|texte= Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:31126966" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a ChloroquineV1
| This area was generated with Dilib version V0.6.33. |  |